Description : The protein IRS-1 is phosphorylated by (A) Protein kinase A (B) Protein kinase C (C) Tyrosine kinase activity of insulin receptor (D) Tyrosine kinase activity of IGF-1 receptor
Last Answer : Answer : B
Description : G-proteins: a. are activated by the binding of an extracellular ligand to a membrane receptor b. can be mutated in tumour cells c. mediate the action of glucocorticoid hormone d. they are inactivated by cholera toxins
Last Answer : are activated by the binding of an extracellular ligand to a membrane receptor
Description : TSH hormone biochemically is a (A) Protein (B) Fat (C) Glycoprotein (D) Carbohydrate 232 MCQs IN BIOCHEMISTRY
Last Answer : Answer : C
Description : Whcih of the following hormone is a peptide of less than ten amino acids? (A) Insulin (B) Growth hormone (C) Oxytocin (D) Parathyroid hormone 228 MCQs IN BIOCHEMISTRY
Description : Adrenocorticotropic hormone (ACTH) is a single polypeptide containing (A) 25 amino acid (B) 39 amino acid (C) 49 amino acid (D) 52 amino acid 208 MCQs IN BIOCHEMISTRY
Description : Binding of thyroxine to its receptors (A) Activates Adenylate cyclase (B) Activates guanylate cyclase (C) Activates a stimulatory G-protein (D) Increases transcription
Last Answer : Answer : D
Description : Binding of insulin to its receptor activates (A) Adenylate cyclase (B) Guanylate cyclase (C) Phospholipase C (D) Tyrosine kinase
Description : Which does NOT occur in a cell stimulated by a steroid hormone? A) The steroid hormone enters the cell by crossing the plasma membrane. B) The hormone binds to a receptor molecule in the ... activates certain genes. E) DNA is transcribed, mRNA is translated, and the result is protein synthesis.
Last Answer : C) The second messenger cyclic AMP is stimulated by the hormone-receptor complex. D) The hormone-receptor complex binds the chromatin and activates certain genes.
Description : Which of the following is a G protein coupled receptor: A. Muscarinic cholinergic receptor B. Nicotinic cholinergic receptor C. Glucocorticoid receptor D. Insulin receptor
Last Answer : A. Muscarinic cholinergic receptor
Description : The only correct statement about hormone receptors is (A) Receptors for protein hormones are present in cytosol (B) Receptors for steroid hormones are membrane bound (C) Hormone-receptor binding is irreversible (D) Receptors can undergo down regulation and up regulatoin
Description : Binding of growth hormone to its receptor results in increased transcription of (A) c-fos gene (B) c-myc gene (C) p-53 gene (D) None of these
Last Answer : Answer : A
Description : Binding of growth hormone to its receptor results in phosphorylation of (A) JAK-2 (B) Growth hormone receptor (C) STATs (D) All of these
Description : Adrenalin is synthesized from (A) Adenine (B) Adenosine (C) Tyrosine (D) Tryptophan 230 MCQs IN BIOCHEMISTRY
Description : Mineralocorticoids increase the tubular reabsorption of (A) Sodium and calcium (B) Sodium and potassium (C) Sodium and chloride (D) Potassium and chloride 224 MCQs IN BIOCHEMISTRY
Description : Tyrosine is required for the synthesis of all of the following except (A) Melatonin (B) Epinephrine (C) Norepinephrine (D) Thyroxine 222 MCQs IN BIOCHEMISTRY
Description : Secretion of thyroid hormones is regulated by (A) Hypothalamus (B) Anterior pituitary (C) Feedback regulation (D) All of these 220 MCQs IN BIOCHEMISTRY
Description : All the following statements about proopiomelanocortin are true except (A) It is made up of 285 amino acids (B) It is synthesised in pars intermedia and anterior lobe of pituitary gland ... ) It is the precursor of corticotropin like intermediate lobe peptide and endorphins 218 MCQs IN BIOCHEMISTRY
Description : Cyclic AMP acts as the second messenger for all of the following except (A) Oxytocin (B) TSH (C) ACTH (D) FSH 216 MCQs IN BIOCHEMISTRY
Description : Normal serum free testosterone in adult men varies between (A) 1–5 ng/dl (B) 6–9 ng/dl (C) 10–30 ng/dl (D) 50–100 ng/dl 214 MCQs IN BIOCHEMISTRY
Description : Calcitonin causes (A) Calcinuria and phosphaturia (B) Decrease in urinary calcium (C) Decrease in urinary phosphorous (D) Increase in blood calcium level 212 MCQs IN BIOCHEMISTRY
Description : ADH (A) Reabsorbs water from renal tubules (B) Excretes water from renal tubules (C) Excretes hypotonic urine (D) Causes low specific gravity of urine 210 MCQs IN BIOCHEMISTRY
Description : Most hormone receptors are localized on the cell membrane and transduce hormone binding into altered levels of intracellular messengers. A limited number of intracellular receptors do exist. Which of ... protein serves as an inhibitor protein blocking the DNA-binding domain of the steroid receptor
Last Answer : Answer: a, d Although most hormone and other messenger receptors are extracellular, intracellular receptors have been identified. The hormone messengers involved for these receptors are primarily ... DNA-binding domain of the receptor. Activation involves the dissociation of the inhibitor protein
Description : Which is associated with a steroid hormone? A) cyclic AMP B) the second messenger system C) production of new proteins D) activation of proteins present in an inactive form E) binding of a protein to a surface receptor on the plasma membrane
Last Answer : C) production of new proteins
Description : Which of the following statement(s) is/are true concerning cell membrane receptors? a. The largest family of cell surface receptors are the G-protein-linked receptors b. Activities of the ... through the use adenylate cyclase d. Tyrosine kinase receptors are considered G-protein-linked receptors
Last Answer : Answer: a, c All water-soluble regulatory molecules bind to the cell surface receptor proteins. Binding of the appropriate ligand evokes an intracellular signal which usually regulates ... are adenylate cyclase, which converts ATP to cAMP, and the polyphosphoinositide-specific phospholipase C
Description : Glucagon activates the enzyme adenylcyclase which causes the increase of blood sugar level. Hence this hormone is called (A) Hypoglycemic factor (B) Hyper glycemic factor (C) Antidiauritic factor (D) Thyrotropin-releasing factor
Description : All the following statements about epidermal growth factor are true except (A) It is a protein (B) It possess quaternary structure (C) Its receptor is made up of a single polypeptide chain (D) Its receptor possesses tyrosine kinase domain
Description : `Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as
Last Answer : `Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as
Description : The glucocorticoid receptor is located: A. On the outer surface of the cell membrane B. On the inner surface of the cell membrane C. In the cytoplasm D. Inside the nucleus
Last Answer : C. In the cytoplasm
Description : Both Acyl carrier protein (ACP) of fatty acid synthetase and coenzyme (CoA) are (A) Contain reactive phosphorylated (B) Contain thymidine (C) Contain phosphopantetheine reactive groups (D) Contain cystine reactive groups
Description : Calcium is important in skeletal muscle contraction because it (a) binds to troponin to remove the masking of active sites on actin for myosin (b) activates the myosin ATPase by binding to it ... filament (d) prevents the formation of bonds between the myosin cross bridges and the actin filament.
Last Answer : (a) binds to troponin to remove the masking of active sites on actin for myosin
Description : Calcium is important in skeletal muscle contraction because it :- (1) binds to troponin to remove the masking of active sites on actin for myosin. (2) activates the myosin ATPase by binding to ... filament. (4) prevents the formation of bonds between the myosin cross bridges and the actin filament.
Last Answer : (1) binds to troponin to remove the masking of active sites on actin for myosin.
Description : Ras proto-oncogene encodes (A) Epidermal growth factor (EGF) (B) Receptor for EGF (C) Signal transducer for EGF (D) Nuclear transcription factor
Description : Fibronectin has binding sites for all of the following except (A) Glycophorin (B) Collagen (C) Heparin (D) Integrin receptor
Description : Insulin binding sites are present on the (A) α-subunits of insulin receptor (B) β-subunits of insulin receptor (C) γ-subunits of insulin receptor (D) α-and β−subunits of insulin receptor
Description : Main glucocorticoid hormone responsible for carbohydrate metabolism is
Last Answer : Main glucocorticoid hormone responsible for carbohydrate metabolism is
Description : Which of the following hormones is considered a glucocorticoid? A) aldosterone B) insulin C) thyroxin D) cortisol E) parathyroid hormone
Last Answer : D) cortisol
Description : The hormone which acts through intracellular receptor protein is
Last Answer : The hormone which acts through intracellular receptor protein is A. Growth hormone B. Prolactin C. Thyroxine D. Adrenaline
Description : Identify A, B and C in the diagramatic representation of the mechanism of hormone action. B A Response 1 C Physiological Responses Select the correct option from the following. (a) A-Steroid Hormone; B- ... ; C - Second Messenger (d) A-Protein Hormone; B-Cyclic AMP; C-Hormone-receptor Complex
Last Answer : (b) A-Protein Hormone; B-Receptor; C-Cyclic AMP
Description : Interleukin-6 is recognized as the cytokine primarily responsible for the alteration in hepatic protein synthesis recognized as the acute phase response. Which of the following statement(s) is/are true ... physiologic role of acute phase proteins are to reduce the systemic effects of tissue damage
Last Answer : Answer: c, d IL-6 is now recognized at the cytokine primarily responsible for the alteration in hepatic synthesis recognized as the acute phase response. Glucocorticoid hormones augment ... that generally inhibit the tissue destruction that is associated with the local initiation of inflammation
Description : The effects of glucocorticoid hormones include: a. increase hepatic glycogen synthesis b. decrease glucose uptake by the adipose tissue c. decrease hepatic gluconeogesis d. increase protein synthesis in the skeletal muscles
Last Answer : . increase hepatic glycogen synthesis
Description : The first protein synthesized by recombinant DNA technology was (A) Streptokinase (B) Human growth hormone (C) Tissue plasminogen activator (D) Human insulin
Description : Growth hormone increases (A) Protein synthesis (B) Lipogenesis (C) Glycogenolysis (D) All of these
Description : During fasting, glucose is phosphorylated mainly by (A) Hexokinase (B) Glucokinase (C) Both (A) and (B) (D) None of these
Description : In citric acid cycle, GDP is phosphorylated by (A) Succinate dehydrogenase (B) Aconitase (C) Succinate thiokinase (D) Fumarse
Description : Glucose 6-phosphate is converted to glucose 1-phosphate in a reaction catalysed by the enzyme phosphoglucomutase, which is (A) Phosphorylated (B) Dephosphorylated (C) Phosphorylated-dephosphorylated (D) Phosphorylated-dephosphorylatedrephosphorylated
Description : All the following vitamins give rise to cofactors that are phosphorylated in the active form except (A) Vitamin A (B) Vitamin B1 (C) Vitamin D (D) Vitamin E
Description : One of the following statement is correct: (A) Glycogen synthase ‘a’ is the phosphorylated (B) cAMP converts glycogen synthase b to ‘a’ (C) Insulin converts glycogen synthase b to a (D) UDP glucose molecules interact and grow into a Glycogen tree
Last Answer : C
Description : Galactose is phosphorylated by galactokinase to form (A) Galactose-6-phosphate (B) Galactose-1, 6 diphosphate (C) Galactose-1-phosphate (D) All of these
Description : The insulin receptor is a: A. Ion channel regulating receptor B. Tyrosine protein kinase receptor C. G-protein coupled receptor D. None of the above
Last Answer : B. Tyrosine protein kinase receptor