β-Subunits of insulin receptor are present (A) Outside the cell membrane (B) In the cell membrane (C) Across the cell membrane (D) In the cytosol

β-Subunits of insulin receptor are present (A) Outside the cell membrane (B) In the cell membrane (C) Across the cell membrane (D) In the cytosol
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α-Subunits of insulin receptor are present (A) Outside the cell membrane (B) In the cell membrane (C) Across the cell membrane (D) In the cytosol

Description : α-Subunits of insulin receptor are present (A) Outside the cell membrane (B) In the cell membrane (C) Across the cell membrane (D) In the cytosol

Last Answer : Answer : A

In the insulin receptor, tyrosine kinase domain is present in (A) α-Subunits (B) β-Subunits (C) γ-Subunits (D) δ-Subunits

Description : In the insulin receptor, tyrosine kinase domain is present in (A) α-Subunits (B) β-Subunits (C) γ-Subunits (D) δ-Subunits

Last Answer : Answer : B

Insulin binding sites are present on the (A) α-subunits of insulin receptor (B) β-subunits of insulin receptor (C) γ-subunits of insulin receptor (D) α-and β−subunits of insulin receptor

Description : Insulin binding sites are present on the (A) α-subunits of insulin receptor (B) β-subunits of insulin receptor (C) γ-subunits of insulin receptor (D) α-and β−subunits of insulin receptor

Last Answer : Answer : A

The only correct statement about hormone receptors is (A) Receptors for protein hormones are present in cytosol (B) Receptors for steroid hormones are membrane bound (C) Hormone-receptor binding is irreversible (D) Receptors can undergo down regulation and up regulatoin

Description : The only correct statement about hormone receptors is (A) Receptors for protein hormones are present in cytosol (B) Receptors for steroid hormones are membrane bound (C) Hormone-receptor binding is irreversible (D) Receptors can undergo down regulation and up regulatoin

Last Answer : Answer : D

All the following statements about TSH are true except (A) It is a glycoprotein (B) It is made up of α- and β-subunits (C) Receptor recognition involves both the subunits (D) Its subunit is identical with those of FSH and LH

Description : All the following statements about TSH are true except (A) It is a glycoprotein (B) It is made up of α- and β-subunits (C) Receptor recognition involves both the subunits (D) Its subunit is identical with those of FSH and LH

Last Answer : Answer : D

Insulin receptor is made up of (A) One α-and one β-subunit (B) Two α-and two β-subunit (C) Two, α two β-and two γ-subunit (D) One α, one β-one γ-and one δ-subunit

Description : Insulin receptor is made up of (A) One α-and one β-subunit (B) Two α-and two β-subunit (C) Two, α two β-and two γ-subunit (D) One α, one β-one γ-and one δ-subunit

Last Answer : Answer : B

Which of the following receptors does not span the cell membrane 7 times a. β-Adrenergic receptor b. Rhodopsin c. 5-HTic receptor d. Mineralocorticoid receptor

Description : Which of the following receptors does not span the cell membrane 7 times a. β-Adrenergic receptor b. Rhodopsin c. 5-HTic receptor d. Mineralocorticoid receptor

Last Answer : Mineralocorticoid receptor

Which one of the following pairs of hormones are the examples of those that can easily pass through the cell membrane of the target cell and bind to a receptor inside it (mostly in the nucleus)?(a) Insulin, glucagon (b) Thyroxine, insulin (c) Somatostatin, oxytocin (d) Cortisol, testosterone

Description : Which one of the following pairs of hormones are the examples of those that can easily pass through the cell membrane of the target cell and bind to a receptor inside it (mostly in the nucleus)? (a) Insulin, glucagon (b) Thyroxine, insulin (c) Somatostatin, oxytocin (d) Cortisol, testosterone

Last Answer : (d) Cortisol, testosterone

81. Which one of the following pairs of hormones are the examples of those that can easily pass through the cell membrane of the target cell and bind to a receptor inside it (mostly in the nucleus) (1) Cortisol, testosterone (2) Insulin, glucagon (3) Thyroxin, Insulin (4) Somatostatin, oxytocin

Description : 81. Which one of the following pairs of hormones are the examples of those that can easily pass through the cell membrane of the target cell and bind to a receptor inside it (mostly in the nucleus) (1) Cortisol, testosterone (2) Insulin, glucagon (3) Thyroxin, Insulin (4) Somatostatin, oxytocin

Last Answer : Cortisol, testosterone

Thyroid stimulating hormone is a dimer. The α-subunits of TSH, LH, FSH are identical. Thus the biological specificity must therefore be β subunit in which the number of amino acids is (A) 78 (B) 112 (C) 130 (D) 199

Description : Thyroid stimulating hormone is a dimer. The α-subunits of TSH, LH, FSH are identical. Thus the biological specificity must therefore be β subunit in which the number of amino acids is (A) 78 (B) 112 (C) 130 (D) 199

Last Answer : Answer : B

The enzymes of β-oxidation are found in (A) Mitochondria (B) Cytosol (C) Golgi apparatus (D) Nucleus

Description : The enzymes of β-oxidation are found in (A) Mitochondria (B) Cytosol (C) Golgi apparatus (D) Nucleus

Last Answer : Answer : A

Insulin increases the permeability of glucose across the plasma membrane of muscle cells by (A) Acting on adenylate cycle (B) By loosening the integrity of the membrane (C) Through Ca2+ ions (D) By membrane cruting the hexose carries of intracellular organelles and making them fuse with the plasma membrane

Description : Insulin increases the permeability of glucose across the plasma membrane of muscle cells by (A) Acting on adenylate cycle (B) By loosening the integrity of the membrane (C) Through Ca2 ... membrane cruting the hexose carries of intracellular organelles and making them fuse with the plasma membrane

Last Answer : Answer : D

Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Description : Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Last Answer : C. Alter its folding or alignment of subunits

Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Description : Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation

Last Answer : C. Alter its folding or alignment of subunits

De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by insulin (C) NADH is required in synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis

Description : De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by ... synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis

Last Answer : Answer : A

The synthesis of glucose from pyruvate by gluconeogenesis (A) Requires the participation of biotin (B) Occurs exclusively in the cytosol (C) Is inhibited by elevated level of insulin (D) Requires oxidation/reduction of FAD

Description : The synthesis of glucose from pyruvate by gluconeogenesis (A) Requires the participation of biotin (B) Occurs exclusively in the cytosol (C) Is inhibited by elevated level of insulin (D) Requires oxidation/reduction of FAD

Last Answer : A

Tyrosine kinase activity is present in (A) α-Adrenergic receptors (B) β-Adrenergic receptors (C) Cholinergic receptors (D) Insulin receptors

Description : Tyrosine kinase activity is present in (A) α-Adrenergic receptors (B) β-Adrenergic receptors (C) Cholinergic receptors (D) Insulin receptors

Last Answer : Answer : D

Which of these statements is incorrect? (a) Enzymes of TCA cycle are present in mitochondrial matrix. (b) Glycolysis occurs in cytosol. (c) Glycolysis operates as long as it is supplied with NAD that can pick up hydrogen atoms. (d) Oxidative phosphorylation takes place in outer mitochondrial membrane

Description : Which of these statements is incorrect? (a) Enzymes of TCA cycle are present in mitochondrial matrix. (b) Glycolysis occurs in cytosol. (c) Glycolysis operates as long as it is supplied ... that can pick up hydrogen atoms. (d) Oxidative phosphorylation takes place in outer mitochondrial membrane

Last Answer : (d) Oxidative phosphorylation takes place in outer mitochondrial membrane

Which of these statements is incorrect ? (1) Enzymes of TCA cycle are present in mitochondrial matrix. (2) Glycolysis occurs in cytosol. (3) Glycolysis operates as long as it is supplied with NAD that can pick up hydrogen atoms. (4) Oxidative phosphorylation takes place in outer mitochondrial membrane.

Description : Which of these statements is incorrect ? (1) Enzymes of TCA cycle are present in mitochondrial matrix. (2) Glycolysis occurs in cytosol. (3) Glycolysis operates as long as it is supplied ... that can pick up hydrogen atoms. (4) Oxidative phosphorylation takes place in outer mitochondrial membrane.

Last Answer : (4) Oxidative phosphorylation takes place in outer mitochondrial membrane.

Oxidation of fatty acids occurs (A) In the cytosol (B) In the matrix of mitochondria (C) On inner mitochondrial membrane (D) On the microsomes

Description : Oxidation of fatty acids occurs (A) In the cytosol (B) In the matrix of mitochondria (C) On inner mitochondrial membrane (D) On the microsomes

Last Answer : Answer : B

Receptors for thyroid hormones are present (A) On the cell membrane (B) Across the cell membrane (C) Inside the cells (D) In association with G-proteins

Description : Receptors for thyroid hormones are present (A) On the cell membrane (B) Across the cell membrane (C) Inside the cells (D) In association with G-proteins

Last Answer : Answer : C

A striking feature of living cells is a marked difference between the composition of the cytosol and the extracellular milieu. Which of the following statement(s) concerning the mechanisms of maintenance of these differences is/are true? a. The cell membrane is able to maintain a 10,000 fold gradient between the extracellular concentration of ionized calcium and the intracellular concentration b. The key to these differences is the fact that the plasma membrane is normally impermeable to sodium, potassium and calcium c. The selectivity of biologic membranes is highly consistent and seldom changes d. The selectivity of cell membranes relates only to ions and not organic compounds

Description : A striking feature of living cells is a marked difference between the composition of the cytosol and the extracellular milieu. Which of the following statement(s) concerning the mechanisms of maintenance ... d. The selectivity of cell membranes relates only to ions and not organic compounds

Last Answer : Answer: a The survival of the cell requires that cytosolic composition be maintained within narrow limits, despite the constant influx of nutrients and the simultaneous outflow of waste. A ... be altered drastically as a result of regulatory or signaling processes that occur within the cell

Which of the following ribosomes are engaged in protein synthesis in animal cell? (a) Ribosomes which occur on nuclear membrane and ER (b) Ribosomes of only cytosol (c) Ribosomes of only nucleolus and cytosol (d) Ribosomes of only mitochondria and cytosol

Description : Which of the following ribosomes are engaged in protein synthesis in animal cell? (a) Ribosomes which occur on nuclear membrane and ER (b) Ribosomes of only cytosol (c) Ribosomes of only nucleolus and cytosol (d) Ribosomes of only mitochondria and cytosol

Last Answer : (a) poleward movement

Ribozymes are (A) Enzymes present in ribosomes (B) Enzymes which combine the ribosomal subunits (C) Enzymes which dissociate (D) Enzymes made up of RNA

Description : Ribozymes are (A) Enzymes present in ribosomes (B) Enzymes which combine the ribosomal subunits (C) Enzymes which dissociate (D) Enzymes made up of RNA

Last Answer : Answer : D

The protein IRS-1 is phosphorylated by (A) Protein kinase A (B) Protein kinase C (C) Tyrosine kinase activity of insulin receptor (D) Tyrosine kinase activity of IGF-1 receptor

Description : The protein IRS-1 is phosphorylated by (A) Protein kinase A (B) Protein kinase C (C) Tyrosine kinase activity of insulin receptor (D) Tyrosine kinase activity of IGF-1 receptor

Last Answer : Answer : B

Binding of insulin to its receptor activates (A) Adenylate cyclase (B) Guanylate cyclase (C) Phospholipase C (D) Tyrosine kinase

Description : Binding of insulin to its receptor activates (A) Adenylate cyclase (B) Guanylate cyclase (C) Phospholipase C (D) Tyrosine kinase

Last Answer : Answer : D

Insulin receptor is a (A) Monomer (B) Dimer (C) Trimer (D) Tetramer

Description : Insulin receptor is a (A) Monomer (B) Dimer (C) Trimer (D) Tetramer

Last Answer : Answer : D

What is the structural feature of insulin receptor?

Description : What is the structural feature of insulin receptor?

Last Answer : Insulin receptor has four subunits, two alpha and two beta subunits. The alpha units are located on the extracellular side, to which insulin binds. The beta subunits are towards cytoplasmic side. Beta subunit has tyrosine kinase activity. 

`Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as

Description : `Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as

Last Answer : `Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as

Receptor sites for neurotransmitters are present on (a) pre-synaptic membrane (b) tips of axons (c) post-synaptic membrane (d) membranes of synaptic vesicles.

Description : Receptor sites for neurotransmitters are present on (a) pre-synaptic membrane (b) tips of axons (c) post-synaptic membrane (d) membranes of synaptic vesicles.

Last Answer : (c) post-synaptic membrane

Which is associated with a steroid hormone? A) cyclic AMP B) the second messenger system C) production of new proteins D) activation of proteins present in an inactive form E) binding of a protein to a surface receptor on the plasma membrane

Description : Which is associated with a steroid hormone? A) cyclic AMP B) the second messenger system C) production of new proteins D) activation of proteins present in an inactive form E) binding of a protein to a surface receptor on the plasma membrane

Last Answer : C) production of new proteins

Receptor sites for neurotransmitters are present on : (1) Pre-synaptic membrane (2) Tips of axons (3) Post-synaptic membrane (4) Membrane of synaptic vesicles

Description : Receptor sites for neurotransmitters are present on : (1) Pre-synaptic membrane (2) Tips of axons (3) Post-synaptic membrane (4) Membrane of synaptic vesicles

Last Answer : (3) Post-synaptic membrane

β-cells of islet of langerhans of the pancreas secrete (A) Insulin (B) Glucagon (C) Somatostatin (D) Pancreatic polypeptide

Description : β-cells of islet of langerhans of the pancreas secrete (A) Insulin (B) Glucagon (C) Somatostatin (D) Pancreatic polypeptide

Last Answer : Answer : A

Which are the cholesterol esters that enter cells through the receptor-mediated endocytosis of lipoproteins hydrolyzed? (A) Endoplasmin reticulum (B) Lysosomes (C) Plasma membrane receptor (D) Mitochondria

Description : Which are the cholesterol esters that enter cells through the receptor-mediated endocytosis of lipoproteins hydrolyzed? (A) Endoplasmin reticulum (B) Lysosomes (C) Plasma membrane receptor (D) Mitochondria

Last Answer : B

The enzyme pyruvate carboxylase is present in (A) Cytosol (B) Mitochondria (C) Nucleus (D) Golgi bodies

Description : The enzyme pyruvate carboxylase is present in (A) Cytosol (B) Mitochondria (C) Nucleus (D) Golgi bodies

Last Answer : Answer : B

The following enzyme of urea cycle is present in cytosol: (A) Argininosuccinic acid synthetase (B) Argininosuccinase (C) Arginase (D) All of these

Description : The following enzyme of urea cycle is present in cytosol: (A) Argininosuccinic acid synthetase (B) Argininosuccinase (C) Arginase (D) All of these

Last Answer : Answer : D

The matrix surrounding the grana in the inner membrane of chloroplasts is (A) Cytosol (B) Frets (C) Stroma (D) Inter-granal lamellae

Description : The matrix surrounding the grana in the inner membrane of chloroplasts is (A) Cytosol (B) Frets (C) Stroma (D) Inter-granal lamellae

Last Answer : (C) Stroma

Most hormone receptors are localized on the cell membrane and transduce hormone binding into altered levels of intracellular messengers. A limited number of intracellular receptors do exist. Which of the following statement(s) is/are true concerning intracellular receptors? a. The messengers or hormones must by lipophilic b. These intracellular receptors generally regulate protein synthesis c. The intracellular receptors are located entirely in the nucleus of the cell d. A heat-shock protein serves as an inhibitor protein blocking the DNA-binding domain of the steroid receptor

Description : Most hormone receptors are localized on the cell membrane and transduce hormone binding into altered levels of intracellular messengers. A limited number of intracellular receptors do exist. Which of ... protein serves as an inhibitor protein blocking the DNA-binding domain of the steroid receptor

Last Answer : Answer: a, d Although most hormone and other messenger receptors are extracellular, intracellular receptors have been identified. The hormone messengers involved for these receptors are primarily ... DNA-binding domain of the receptor. Activation involves the dissociation of the inhibitor protein

Cell regulation can be thought of as the effector side of cell communication. Most commonly cell regulation occurs by means of extracellular chemical messengers. Which of the following statement(s) is/are true concerning these messengers? a. Paracrine regulation involves a messenger which is produced and acts systemically b. The extracellular signal or stimulus is received by a receptor on or in the target cell c. Neurocrine regulation depends on a physical connection between the neuron and the target cell d. Most hormones, local mediators, and neurotransmitters readily cross the cell plasma membrane

Description : Cell regulation can be thought of as the effector side of cell communication. Most commonly cell regulation occurs by means of extracellular chemical messengers. Which of the following statement(s ... d. Most hormones, local mediators, and neurotransmitters readily cross the cell plasma membrane

Last Answer : Answer: b, c Depending on how the extracellular messenger arrives, cell regulation can be classified as paracrine, endocrine, or neurocrine. In paracrine regulation, a chemical messenger ... , local mediators, and neurotransmitters are water-soluble and cannot readily cross the plasma membrane

Which of the following statement(s) is/are true concerning cell membrane receptors? a. The largest family of cell surface receptors are the G-protein-linked receptors b. Activities of the G-protein involve binding and hydrolysis of ATP c. The G protein receptor generates an intracellular messenger commonly through the use adenylate cyclase d. Tyrosine kinase receptors are considered G-protein-linked receptors

Description : Which of the following statement(s) is/are true concerning cell membrane receptors? a. The largest family of cell surface receptors are the G-protein-linked receptors b. Activities of the ... through the use adenylate cyclase d. Tyrosine kinase receptors are considered G-protein-linked receptors

Last Answer : Answer: a, c All water-soluble regulatory molecules bind to the cell surface receptor proteins. Binding of the appropriate ligand evokes an intracellular signal which usually regulates ... are adenylate cyclase, which converts ATP to cAMP, and the polyphosphoinositide-specific phospholipase C

A _____ is a protein receptor on the surface of macrophages, dendritic cells, and endothelial cells that allow them to recognize foreign cell markers. a. Toll-like receptor (TLR) b. pathogen-associated c. Membrane attack complex (MAC) d. Natural killer cells (NK)

Description : A _____ is a protein receptor on the surface of macrophages, dendritic cells, and endothelial cells that allow them to recognize foreign cell markers. a. Toll-like receptor (TLR) b. pathogen-associated c. Membrane attack complex (MAC) d. Natural killer cells (NK)

Last Answer : b. pathogen-associated

Which does NOT occur in a cell stimulated by a steroid hormone? A) The steroid hormone enters the cell by crossing the plasma membrane. B) The hormone binds to a receptor molecule in the cytoplasm. C) The second messenger cyclic AMP is stimulated by the hormone-receptor complex. D) The hormone-receptor complex binds the chromatin and activates certain genes. E) DNA is transcribed, mRNA is translated, and the result is protein synthesis.

Description : Which does NOT occur in a cell stimulated by a steroid hormone? A) The steroid hormone enters the cell by crossing the plasma membrane. B) The hormone binds to a receptor molecule in the ... activates certain genes. E) DNA is transcribed, mRNA is translated, and the result is protein synthesis.

Last Answer : C) The second messenger cyclic AMP is stimulated by the hormone-receptor complex. D) The hormone-receptor complex binds the chromatin and activates certain genes.

The glucocorticoid receptor is located: A. On the outer surface of the cell membrane B. On the inner surface of the cell membrane C. In the cytoplasm D. Inside the nucleus

Description : The glucocorticoid receptor is located: A. On the outer surface of the cell membrane B. On the inner surface of the cell membrane C. In the cytoplasm D. Inside the nucleus

Last Answer : C. In the cytoplasm

Proteins that are secreted by cells are generally a. not synthesized on membrane-bound ribosomes b. initially synthesized with a signal peptide or leader sequence at their C terminal c. found in vesicles and secretory granules d. moved across the cell membranes by endocytosis e. secreted in a form that is larger than the form present in the endoplasmic reticulum

Description : Proteins that are secreted by cells are generally a. not synthesized on membrane-bound ribosomes b. initially synthesized with a signal peptide or leader sequence at their C terminal c. found in ... endocytosis e. secreted in a form that is larger than the form present in the endoplasmic reticulum

Last Answer : found in vesicles and secretory granules

Protein synthesis in an animal cell occurs (a) only on the ribosomes present in cytosol (b) only on ribosome attached to the nuclear envelope and endoplasmic reticulum (c) on ribosome present in the nucleolus as well as in cytoplasm (d) on ribosomes present in cytoplasm as well as in mitochondria.

Description : Protein synthesis in an animal cell occurs (a) only on the ribosomes present in cytosol (b) only on ribosome attached to the nuclear envelope and endoplasmic reticulum (c) on ribosome present in the ... as well as in cytoplasm (d) on ribosomes present in cytoplasm as well as in mitochondria.

Last Answer : (d) on ribosomes present in cytoplasm as well as in mitochondria.

.Protein synthesis in an animal cell occurs (a) only on the ribosomes present in cytosol (b) only on ribosome attached to the nuclear envelope and endoplasmic reticulum (c) on ribosome present in the nucleolus as well as in cytoplasm (d) on ribosomes present in cytoplasm as well as in mitochondria.

Description : .Protein synthesis in an animal cell occurs (a) only on the ribosomes present in cytosol (b) only on ribosome attached to the nuclear envelope and endoplasmic reticulum (c) on ribosome present in the ... as well as in cytoplasm (d) on ribosomes present in cytoplasm as well as in mitochondria.

Last Answer : (d) on ribosomes present in cytoplasm as well as in mitochondria.

The β3 adrenoceptor differs from the other subtypes of β receptor in that it: A. Is not blocked by the conventional doses of propranolol B. Is located primarily in the heart C. Regulates blood sugar level D. Is not coupled to G proteins

Description : The β3 adrenoceptor differs from the other subtypes of β receptor in that it: A. Is not blocked by the conventional doses of propranolol B. Is located primarily in the heart C. Regulates blood sugar level D. Is not coupled to G proteins

Last Answer : A. Is not blocked by the conventional doses of propranolol

The β 3 adrenoceptor differs from the other subtypes of β receptor in that it: A. Is not blocked by the conventional doses of propranolol B. Is located primarily in the heart C. Regulates blood sugar level D. Is not coupled to G proteins

Description : The β 3 adrenoceptor differs from the other subtypes of β receptor in that it: A. Is not blocked by the conventional doses of propranolol B. Is located primarily in the heart C. Regulates blood sugar level D. Is not coupled to G proteins

Last Answer : A. Is not blocked by the conventional doses of propranolol

Bulk transport across cell membrane is accomplished by (A) Phagocytosis (B) Pinocytosis (C) Extrusion (D) All of these

Description : Bulk transport across cell membrane is accomplished by (A) Phagocytosis (B) Pinocytosis (C) Extrusion (D) All of these

Last Answer : D

Degradations of Hb takes place in (A) Mitochondrion (B) Erythrocytes (C) Cytosol of cell (D) R.E. cells

Description : Degradations of Hb takes place in (A) Mitochondrion (B) Erythrocytes (C) Cytosol of cell (D) R.E. cells

Last Answer : Answer : D