Description : Binding of growth hormone to its receptor results in phosphorylation of (A) JAK-2 (B) Growth hormone receptor (C) STATs (D) All of these
Last Answer : Answer : D
Description : Phosphorylated IRS-1 activates GRB-2 which is (A) G-protein receptor binding protein-2 (B) Growth factor receptor binding protein-2 (C) Growth hormone receptor binding protein-2 (D) Glucocorticoid receptor binding protein-2 226 MCQs IN BIOCHEMISTRY
Last Answer : Answer : B
Description : Transcription of structural genes of lac operon is prevented by binding of the repressor tetramer to (A) i gene (B) Operator locus (C) Promoter (D) z gene
Description : The only correct statement about hormone receptors is (A) Receptors for protein hormones are present in cytosol (B) Receptors for steroid hormones are membrane bound (C) Hormone-receptor binding is irreversible (D) Receptors can undergo down regulation and up regulatoin
Description : Ras proto-oncogene encodes (A) Epidermal growth factor (EGF) (B) Receptor for EGF (C) Signal transducer for EGF (D) Nuclear transcription factor
Last Answer : Answer : C
Description : `Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as
Last Answer : `Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as
Description : Most hormone receptors are localized on the cell membrane and transduce hormone binding into altered levels of intracellular messengers. A limited number of intracellular receptors do exist. Which of ... protein serves as an inhibitor protein blocking the DNA-binding domain of the steroid receptor
Last Answer : Answer: a, d Although most hormone and other messenger receptors are extracellular, intracellular receptors have been identified. The hormone messengers involved for these receptors are primarily ... DNA-binding domain of the receptor. Activation involves the dissociation of the inhibitor protein
Description : G-proteins: a. are activated by the binding of an extracellular ligand to a membrane receptor b. can be mutated in tumour cells c. mediate the action of glucocorticoid hormone d. they are inactivated by cholera toxins
Last Answer : are activated by the binding of an extracellular ligand to a membrane receptor
Description : Which is associated with a steroid hormone? A) cyclic AMP B) the second messenger system C) production of new proteins D) activation of proteins present in an inactive form E) binding of a protein to a surface receptor on the plasma membrane
Last Answer : C) production of new proteins
Description : Retinoblastoma can result from a mutation in (A) ras proto-oncogene (B) erbB proto-oncogene (C) p 53 gene (D) RB 1 gene
Description : P 53 gene: (A) A proto-oncogene (B) An oncogene (C) A tumour suppressor gene (D) None of these
Description : Hormone which regulate gene expression or chromosome by interation of hormone receptor complex with the genome are
Last Answer : Hormone which regulate gene expression or chromosome by interation of hormone receptor complex with the genome are
Description : How does steroid hormone influence the cellular activities? (a) Using aquaporin channels ‘as second messenger’ (b) Changing the permeability of the cell membrane (c) Binding to DNA and forming a gene-hormone complex (d) Activating cyclic AMP located on the cell membrane
Last Answer : (c) Binding to DNA and forming a gene-hormone complex
Description : The condition that results when there is an increased production of human growth hormone in an adult is termed A) Cushing's syndrome. B) Addison's disease. C) gigantism. D) dwarfism. E) acromegaly.
Last Answer : E) acromegaly.
Description : Binding of thyroxine to its receptors (A) Activates Adenylate cyclase (B) Activates guanylate cyclase (C) Activates a stimulatory G-protein (D) Increases transcription
Description : Binding of insulin to its receptor activates (A) Adenylate cyclase (B) Guanylate cyclase (C) Phospholipase C (D) Tyrosine kinase
Description : The ‘rho’ (ρ) factor is involved (A) To increase the rate of RNA synthesis (B) In binding catabolite repressor to the promoter region (C) In proper termination of transcription (D) To allow proper initiation of transcriptide
Description : The function of a repressor protein in an operon system is to prevent synthesis by binding to (A) The ribosome (B) A specific region of the operon preventing transcription of structural genes (C) The RNA polymerase (D) A specific region of the mRNA preventing translation to protein
Description : In the process of transcription in bacterial cells (A) Initiation requires rho protein (B) RNA polymerase incorporates methylated bases in correct sequence (C) Both the sigma unit and core ... RNA polymerase are required for accurate promotor site binding (D) Primase is necessary for initiation
Description : Fibronectin has binding sites for all of the following except (A) Glycophorin (B) Collagen (C) Heparin (D) Integrin receptor
Description : Insulin binding sites are present on the (A) α-subunits of insulin receptor (B) β-subunits of insulin receptor (C) γ-subunits of insulin receptor (D) α-and β−subunits of insulin receptor
Last Answer : Answer : A
Description : What is the best ankle brace available in India fos ankle ligament injury?
Last Answer : protect.ankle laceup from the house of Pushpanjali medi India Pvt.Ltd. Offers a uniqe ankle brace with medial & lateral stabilization shell for ankle ligament injury, instability and after sprains
Description : Acromegaly results from overproduction of (A) ACTH during childhood (B) TSH during adult life (C) Growth hormone during childhood (D) Growth hormone during adult life HORMONE METABOLISM 219
Description : Acromegaly results due to excessive release of (A) Thyroxine (B) Growth hormone (C) Insulin (D) Glucagon
Description : The region of the Lac operon which must be free from structural gene transcription to occur is (A) The operator locus (B) The promoter site (C) The ‘a’ gene (D) The ‘i’ gene
Description : Mutations in promoter regions of genes can cause (A) Premature termination of translation (B) Change in reading frame of downstream structural gene (C) Decreased efficiency of transcription (D) All of these
Description : All of the following statements about eukaryotic promoters are true except (A) They may be located upstream or down stream from the structural gene (B) They have two consensus sequences ( ... (D) Mutations in promoter region can decrease the efficiency of transcription of the structural gene
Description : To commence structural gene transcription the region which should be free on lac operation is (A) Promoter site (B) Operator locus (C) Y gene (D) A gene
Description : Secretion of androgens is increased by (A) LH (B) FSH (C) ACTH (D) Growth hormone
Description : Growth hormone causes hyperglycemia. It is a result of (A) Decreased peripheral utilization of glucose (B) Decreased hepatic production via gluconeogenesis (C) Increased glycolysis in muscle (D) Decrersed lipolysis
Description : Release of free fatty acids from adipose tissue is increased by all of the following except (A) Glucagon (B) Epinephrine (C) Growth hormone (D) Insulin
Description : Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) ... holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus
Description : Binding of RNA polymerase holoenzyme to the promoter region of lac operon is facilitated by (A) Catabolite gene activator protein (CAP) (B) cAMP (C) CAP-cAMP complex (D) None of these
Description : During transcription, the DNA site at which RNA polymerase binds is called (a) promoter (b) regulator (c) receptor (d) enhancer.
Last Answer : d) enhancer
Last Answer : (a) promoter
Description : Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above
Last Answer : D. All of the above
Description : Hormone that bind to cell surface receptor and require the second messenger camp is (A) Antidiuretic hormone (B) Cholecystokinin (C) Calcitriol (D) Gastrin
Description : Hormone that binds to intracellular receptor is (A) Adrenocorticotropic hormone (B) Thyroxine (C) Follicle stimulating hormone (D) Glucagon
Description : The _____ cell contains on its surface a CD4 receptor site that enhances binding to the macrophage. a. Helper T b. molecular patterns (PAMPs) c. plasma d. B
Last Answer : a. IgG
Description : A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the ... is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs
Last Answer : Answer: a, b, c, d, e Tumor cachexia appears to be mediated by TNFa. Lipopolysaccharide (LPS), as well as other cytokines, activate a variety of inflammatory cells, most ... chronic syndromes of anorexia, weight loss, and cachexia that are associated with both chronic infection and malignancy
Description : Hormone receptors that stimulate cAMP production (A) are part of a complex of two proteins that transform the external signal into internal cAMP production (B) are proteins distinct and separate from those ... binding of the hormone (D) are not very specific and bind a number of different hormones
Description : Progesterone is transported in blood by (A) Transcortin (B) Sex hormone binding globulin (C) Albumin (D) Testosterone estrogen binding globulin
Description : When thyroxine binding globulin and thyroxine binding pre-albumin are saturated with thyroxine, the excess hormone is transported by (A) Albumin (B) Gamma globulins (C) Transcortin (D) None of these
Description : Which of the following statement(s) is/are true concerning cell membrane receptors? a. The largest family of cell surface receptors are the G-protein-linked receptors b. Activities of the ... through the use adenylate cyclase d. Tyrosine kinase receptors are considered G-protein-linked receptors
Last Answer : Answer: a, c All water-soluble regulatory molecules bind to the cell surface receptor proteins. Binding of the appropriate ligand evokes an intracellular signal which usually regulates ... are adenylate cyclase, which converts ATP to cAMP, and the polyphosphoinositide-specific phospholipase C
Description : _____ cells have antibodies on their surface that perform receptor functions by binding to antigen (epitope). a. T b. B c. NK d. A-C are correct
Last Answer : b. B
Description : Clonal selection includes a. Antigen-receptor binding on B cells. b. Antibody secretion recognizing same epitope as on B cell receptors. c. Differentiation of B cells into plasma cells and memory cells. d. All the above (A—C) are correct.
Last Answer : d. All the above (A—C) are correct.
Description : The function of a viral capsid is A.protection against the viral genome from physical and enzymatic destruction B.providing binding sites that enable the virus to attach to specific receptor sites on the host ... C.serving as a vehicle of transmission from one host to another D.all of the above
Last Answer : D.all of the above
Description : Aliskiren acts by (A) inhibiting the conversion of Angiotensin I to II (B) inhibiting the release of rennin (C) inhibiting the binding of Angiotensin II to the receptor (D) inhibiting the action of aldosterone
Last Answer : (B) inhibiting the release of rennin
Description : All the following statements about epidermal growth factor are true except (A) It is a protein (B) It possess quaternary structure (C) Its receptor is made up of a single polypeptide chain (D) Its receptor possesses tyrosine kinase domain
Description : A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic ... in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis
Last Answer : Answer: a, c One of the earliest consequence of a surgical procedure is the rise in levels of circulating cortisol that occur in response to a sudden outpouring of ACTH ... hepatic glucose production, and, with other hormones (epinephrine and glucocorticoids), gluconeogenesis is maintained