The major metabolite of progesterone is (A) Pregnenolone (B) Pregnanediol (C) Estradiol (D) Norethindrone

The major metabolite of progesterone is (A) Pregnenolone (B) Pregnanediol (C) Estradiol (D) Norethindrone
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Synthetic progesterone used in oral contraceptive is (A) Norethindrone (B) Pregnenolone (C) Androstenodione (D) Stilbestrol

Description : Synthetic progesterone used in oral contraceptive is (A) Norethindrone (B) Pregnenolone (C) Androstenodione (D) Stilbestrol

Last Answer : Answer : A

A common intermediate in the synthesis of all the steroid hormones is (A) Pregnenolone (B) 17-Hydroxypregnenolone (C) Corticosterone (D) Progesterone

Description : A common intermediate in the synthesis of all the steroid hormones is (A) Pregnenolone (B) 17-Hydroxypregnenolone (C) Corticosterone (D) Progesterone

Last Answer : Answer : A

In the biosynthesis of testosterone the rate limiting step is conversion of (A) Cholesterol to pregnenolone (B) Pregnenolone to progesterone (C) Progesterone to 17 α-hydroxy progesterone (D) 17 α-Hydroxy progesterone to androstenedione

Description : In the biosynthesis of testosterone the rate limiting step is conversion of (A) Cholesterol to pregnenolone (B) Pregnenolone to progesterone (C) Progesterone to 17 α-hydroxy progesterone (D) 17 α-Hydroxy progesterone to androstenedione

Last Answer : Answer : A

Select the progestin preparation for coadministration with estrogen for hormone replacement therapy that does not counteract the beneficial effect of the latter on lipid profile due to lack of androgenic activity: A. Micronized oral progesterone B. Norethindrone C. Lynestrenol D. Medroxyprogesterone acetate (p. 281-282)

Description : Select the progestin preparation for coadministration with estrogen for hormone replacement therapy that does not counteract the beneficial effect of the latter on lipid profile due to lack of ... oral progesterone B. Norethindrone C. Lynestrenol D. Medroxyprogesterone acetate (p. 281-282)

Last Answer : Select the indication for which a progestin is used alone without combining with an estrogen: A. Threatened abortion B. Dysfunctional uterine bleeding C. Hormone replacement therapy D. Premenstrual tension

A common intermediate in the synthesis of cortisol and aldosterone is (A) Progesterone (B) Testosterone (C) Estradiol (D) None of these

Description : A common intermediate in the synthesis of cortisol and aldosterone is (A) Progesterone (B) Testosterone (C) Estradiol (D) None of these

Last Answer : Answer : A

The immediate cause of induction of ovulation in human female is the large plasma surge of (a) LH (b) FSH (c) progesterone (d) estradiol.

Description : The immediate cause of induction of ovulation in human female is the large plasma surge of (a) LH (b) FSH (c) progesterone (d) estradiol.

Last Answer : (a) LH

Duodenum has characteristic Brunner’s gland which secrete two hormones called (a) kinase, estrogen (b) secretin, cholecystokinin (c) prolactin, parathormone (d) estradiol, progesterone

Description : Duodenum has characteristic Brunner’s gland which secrete two hormones called (a) kinase, estrogen (b) secretin, cholecystokinin (c) prolactin, parathormone (d) estradiol, progesterone

Last Answer : (b) secretin, cholecystokinin

Precursor of ACTH is (A) Cholesterol (B) Pregnenolone (C) Corticotropin (D) Pro-opiomelanocortin

Description : Precursor of ACTH is (A) Cholesterol (B) Pregnenolone (C) Corticotropin (D) Pro-opiomelanocortin

Last Answer : Answer : D

The precursor of testosterone is (A) Aldosterone (B) Methyl testosterone (C) Estrone (D) Pregnenolone

Description : The precursor of testosterone is (A) Aldosterone (B) Methyl testosterone (C) Estrone (D) Pregnenolone

Last Answer : Answer : D

Main metabolic end product of cholesterol: (A) Coprosterol (B) 5-pregnenolone (C) Bile acid (D) Glycine

Description : Main metabolic end product of cholesterol: (A) Coprosterol (B) 5-pregnenolone (C) Bile acid (D) Glycine

Last Answer : Answer : C

Pregnanediol?

Description : Pregnanediol?

Last Answer : DefinitionPregnanediol is an inactive product that forms when the body breaks down the hormone progesterone. A test can be done to measure the amount of pregnanediol in urine. The urine test offers ... this test was used to monitor pregnancies and check for possible problems with the ovaries or adre

The following is/are beneficial in endometriosis: A. Norethindrone B. Nafarelin C. Danazol D. All of the above

Description : The following is/are beneficial in endometriosis: A. Norethindrone B. Nafarelin C. Danazol D. All of the above

Last Answer : D. All of the above

Conversion of testosterone to estradiol requires the enzyme: (A) Aromatase (B) Dehydrogenase (C) Lyase (D) Isomerase HORMONE METABOLISM 215

Description : Conversion of testosterone to estradiol requires the enzyme: (A) Aromatase (B) Dehydrogenase (C) Lyase (D) Isomerase HORMONE METABOLISM 215

Last Answer : Answer : A

Stein-leventhal syndrome is due to overproduction of (A) Estrogens (B) Androgens (C) Gastogens (D) Ethinyl estradiol

Description : Stein-leventhal syndrome is due to overproduction of (A) Estrogens (B) Androgens (C) Gastogens (D) Ethinyl estradiol

Last Answer : Answer : B

The serum estradiol level in women during 21–30 days of menstrual cycle is (A) 10-20 pg/ml (B) 22-66 pg/ml (C) 73-149 pg/ml (D) 1000 pg/ml

Description : The serum estradiol level in women during 21–30 days of menstrual cycle is (A) 10-20 pg/ml (B) 22-66 pg/ml (C) 73-149 pg/ml (D) 1000 pg/ml

Last Answer : Answer : C

The serum estradiol level in women during 11–20 days of menstrual cycle is (A) 5–30 pg/ml (B) 50–300 pg/ml (C) 500–900 pg/ml (D) 1000 pg/ml

Description : The serum estradiol level in women during 11–20 days of menstrual cycle is (A) 5–30 pg/ml (B) 50–300 pg/ml (C) 500–900 pg/ml (D) 1000 pg/ml

Last Answer : Answer : B

The serum estradiol level in women during 1–10 days of menstrual cycle is (A) 0–10 pg/ml (B) 12–20 pg/ml (C) 24–68 pg/ml (D) 80–100 pg/ml

Description : The serum estradiol level in women during 1–10 days of menstrual cycle is (A) 0–10 pg/ml (B) 12–20 pg/ml (C) 24–68 pg/ml (D) 80–100 pg/ml

Last Answer : Answer : C

The serum estradiol level in men is (A) 0–5 pg/ml (B) 5–10 pg/ml (C) 24–68 pg/ml (D) 40–60 pg/ml

Description : The serum estradiol level in men is (A) 0–5 pg/ml (B) 5–10 pg/ml (C) 24–68 pg/ml (D) 40–60 pg/ml

Last Answer : Answer : C

During late pregnancy, the major source of progesterone is (A) Adrenal cortex (B) Placenta (C) Corpus luteum (D) Graafian follicles

Description : During late pregnancy, the major source of progesterone is (A) Adrenal cortex (B) Placenta (C) Corpus luteum (D) Graafian follicles

Last Answer : Answer : B

Methylmalonyl CoA is a metabolite of (A) Valine (B) Leucine (C) Isoleucine (D) All of these

Description : Methylmalonyl CoA is a metabolite of (A) Valine (B) Leucine (C) Isoleucine (D) All of these

Last Answer : Answer : A

N-Formiminoglutamate is a metabolite of (A) Glutamate (B) Histidine (C) Tryptophan (D) Methionine

Description : N-Formiminoglutamate is a metabolite of (A) Glutamate (B) Histidine (C) Tryptophan (D) Methionine

Last Answer : Answer : B

The chief metabolite of catecholamines is (A) Metanephrine (B) Normetanephrine (C) 3, 4-Dihydroxymandelic acid (D) Vanillylmandelic acid

Description : The chief metabolite of catecholamines is (A) Metanephrine (B) Normetanephrine (C) 3, 4-Dihydroxymandelic acid (D) Vanillylmandelic acid

Last Answer : Answer : D

This abnormal metabolite may be responsible for the neurological manifestation of pernicious anemia. (A) Taurine (B) Methyl malonic acid (C) Xanthurenic acid (D) Phenyl pyruvic acid

Description : This abnormal metabolite may be responsible for the neurological manifestation of pernicious anemia. (A) Taurine (B) Methyl malonic acid (C) Xanthurenic acid (D) Phenyl pyruvic acid

Last Answer : Answer : B

This abnormal metabolite may be responsible for the neurological manifestation of pernicious anemia: (A) Taurine (B) Methyl malonic acid (C) Xantherunic acid (D) Phenyl pyruvic acid

Description : This abnormal metabolite may be responsible for the neurological manifestation of pernicious anemia: (A) Taurine (B) Methyl malonic acid (C) Xantherunic acid (D) Phenyl pyruvic acid

Last Answer : Answer : A

The most potent Vitamin D metabolite is (A) 25-Hydroxycholecalciferol (B) 1,25-Dihydroxycholecalciferol (C) 24, 25-Dihydroxycholecalciferol (D) 7-Dehydrocholesterol

Description : The most potent Vitamin D metabolite is (A) 25-Hydroxycholecalciferol (B) 1,25-Dihydroxycholecalciferol (C) 24, 25-Dihydroxycholecalciferol (D) 7-Dehydrocholesterol

Last Answer : Answer : B

A metabolite which is common to pathways of cholesterol biosynthesis from acetyl-CoA and cholecalciferol formation from cholesterol is (A) Zymosterol (B) Lumisterol (C) Ergosterol (D) 7 Dehydrocholesterol

Description : A metabolite which is common to pathways of cholesterol biosynthesis from acetyl-CoA and cholecalciferol formation from cholesterol is (A) Zymosterol (B) Lumisterol (C) Ergosterol (D) 7 Dehydrocholesterol

Last Answer : Answer : D

At normal levels of creatinine in the blood, this metabolite is (A) Filtered at the glomerulus but not secreted nor reabsorbed by the tubule (B) Secreted by the tubule (C) Reabsorbed by the tubule (D) Secreted and reabsorbed by tubule

Description : At normal levels of creatinine in the blood, this metabolite is (A) Filtered at the glomerulus but not secreted nor reabsorbed by the tubule (B) Secreted by the tubule (C) Reabsorbed by the tubule (D) Secreted and reabsorbed by tubule

Last Answer : Answer : A

Xanthuric acid is an abnormal metabolite of (A) Xanthine (B) Uric acid (C) Tyrosine (D) Tryptophan

Description : Xanthuric acid is an abnormal metabolite of (A) Xanthine (B) Uric acid (C) Tyrosine (D) Tryptophan

Last Answer : Answer : D

The metabolite which sustains urea cycle is (A) Ornithine (B) Citrulline (C) Carbamoyl phosphate (D) n-acetyl glutamate

Description : The metabolite which sustains urea cycle is (A) Ornithine (B) Citrulline (C) Carbamoyl phosphate (D) n-acetyl glutamate

Last Answer : Answer : C

All the following statements about serotonin are true except (A) It causes vasolidatation (B) It causes bronchoconstriction (C) It is metabolized by monoamine oxidase (D) Its metabolite is 5-hydroxyindole acetic acid

Description : All the following statements about serotonin are true except (A) It causes vasolidatation (B) It causes bronchoconstriction (C) It is metabolized by monoamine oxidase (D) Its metabolite is 5-hydroxyindole acetic acid

Last Answer : Answer : A

Pentagastrin is a (A) Naturally occurring form of gastrin (B) Inactive metabolite of gastrin (C) Active metabolite of gastrin (D) Synthetic form of gastrin

Description : Pentagastrin is a (A) Naturally occurring form of gastrin (B) Inactive metabolite of gastrin (C) Active metabolite of gastrin (D) Synthetic form of gastrin

Last Answer : Answer : D

Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate

Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate

Last Answer : A

Blood pressure may be increased by the excessive secretion of (1) Thyroxine (2) Testosterone (3) Estradiol (4) Estrol

Description : Blood pressure may be increased by the excessive secretion of (1) Thyroxine (2) Testosterone (3) Estradiol (4) Estrol

Last Answer : (1) Thyroxine Explanation: With its excess secretion, also known as hyper secretion, thyroxin (T4) causes an increased heart rate, high blood pressure, possible palpitations, and could lead to heart failure. It is related to hyperthyroidism.

Which of the following events is not associated with ovulation in human female? (a) Release of secondary oocyte (b) LH surge (c) Decrease in estradiol (d) Full development of Graafian follicle

Description : Which of the following events is not associated with ovulation in human female? (a) Release of secondary oocyte (b) LH surge (c) Decrease in estradiol (d) Full development of Graafian follicle

Last Answer : (c) Decrease in estradiol

Which of the following is an amino acid derived hormone? (a) Epinephrine (b) Ecdysone (c) Estradiol (d) Estriol

Description : Which of the following is an amino acid derived hormone? (a) Epinephrine (b) Ecdysone (c) Estradiol (d) Estriol

Last Answer : (a) Epinephrine

The estrogen commonly used for hormone replacement therapy in menopausal women is: A. Ethinylestradiol B. Estradiol benzoate C. Diethylstilbestrol D. Conjugated estrogens

Description : The estrogen commonly used for hormone replacement therapy in menopausal women is: A. Ethinylestradiol B. Estradiol benzoate C. Diethylstilbestrol D. Conjugated estrogens

Last Answer : D. Conjugated estrogen

Transdermal estradiol differs from oral estrogen therapy in that it: A. Causes less induction of hepatic synthesis of clotting factors B. Does not inhibit FSH secretion C. Does not affect vaginal cytology D. All of the above are correct

Description : Transdermal estradiol differs from oral estrogen therapy in that it: A. Causes less induction of hepatic synthesis of clotting factors B. Does not inhibit FSH secretion C. Does not affect vaginal cytology D. All of the above are correct

Last Answer : A. Causes less induction of hepatic synthesis of clotting factors

Which of the following is an amino acid derived hormone ? (1) Epinephrine (2) Ecdysone (3) Estradiol (4) Estriol

Description : Which of the following is an amino acid derived hormone ? (1) Epinephrine (2) Ecdysone (3) Estradiol (4) Estriol

Last Answer : (1) Epinephrine

Blood pressure may be increased by the excessive secretion of (1) Thyroxine (2) Testosterone (3) Estradiol (4) Estrol

Description : Blood pressure may be increased by the excessive secretion of (1) Thyroxine (2) Testosterone (3) Estradiol (4) Estrol 

Last Answer : Thyroxine

Lack of Glucocorticoids and mineral corticoids might be consequence of which of the following defects in the adrenal cortex? (A) Androstenadione deficiency (B) Estrone deficiency (C) 17 α-OH progesterone deficiency (D) C- α-Hydroxylase deficiency

Description : Lack of Glucocorticoids and mineral corticoids might be consequence of which of the following defects in the adrenal cortex? (A) Androstenadione deficiency (B) Estrone deficiency (C) 17 α-OH progesterone deficiency (D) C- α-Hydroxylase deficiency

Last Answer : Answer : D

Placenta secretes all of the following except (A) FSH (B) Progesterone (C) Estrogen (D) Chorionic gonadotropin HORMONE METABOLISM 225

Description : Placenta secretes all of the following except (A) FSH (B) Progesterone (C) Estrogen (D) Chorionic gonadotropin HORMONE METABOLISM 225

Last Answer : Answer : A

A hormone used for detection of pregnancy is (A) Estrogen (B) Progesterone (C) Oxytocin (D) Chorionic gonadotropin

Description : A hormone used for detection of pregnancy is (A) Estrogen (B) Progesterone (C) Oxytocin (D) Chorionic gonadotropin

Last Answer : Answer : D

Women become susceptible to osteoporosis after menopause due to decreased (A) Secretion of Parathormone (B) Conversion of vitamin D into calcitriol (C) Secretion of estrogen (D) Secretion of progesterone

Description : Women become susceptible to osteoporosis after menopause due to decreased (A) Secretion of Parathormone (B) Conversion of vitamin D into calcitriol (C) Secretion of estrogen (D) Secretion of progesterone

Last Answer : Answer : C

Secretion of progesterone (A) Is more in first half of menstrual cycle than in second half (B) Is more in second half of menstrual cycle than in first half (C) Remains constant during menstrual cycle (D) Decreases during pregnancy

Description : Secretion of progesterone (A) Is more in first half of menstrual cycle than in second half (B) Is more in second half of menstrual cycle than in first half (C) Remains constant during menstrual cycle (D) Decreases during pregnancy

Last Answer : Answer : B

Progesterone is transported in blood by (A) Transcortin (B) Sex hormone binding globulin (C) Albumin (D) Testosterone estrogen binding globulin

Description : Progesterone is transported in blood by (A) Transcortin (B) Sex hormone binding globulin (C) Albumin (D) Testosterone estrogen binding globulin

Last Answer : Answer : A

All the following statements about transcortin are true except (A) It is synthesised in liver (B) It transports glucocorticoids (C) It transports aldosterone (D) It transports progesterone

Description : All the following statements about transcortin are true except (A) It is synthesised in liver (B) It transports glucocorticoids (C) It transports aldosterone (D) It transports progesterone

Last Answer : Answer : C

Zona glomerulosa of adrenal cortex synthesises (A) Glucocorticoids (B) Mineralocorticoids (C) Androgens (D) Estrogen and progesterone HORMONE METABOLISM 223

Description : Zona glomerulosa of adrenal cortex synthesises (A) Glucocorticoids (B) Mineralocorticoids (C) Androgens (D) Estrogen and progesterone HORMONE METABOLISM 223

Last Answer : Answer : A

In structure and function, HCG resembles (A) FSH (B) LH (C) GnRH (D) Progesterone

Description : In structure and function, HCG resembles (A) FSH (B) LH (C) GnRH (D) Progesterone

Last Answer : Answer : B

Young women are protected against myocardial infaracation because of the activity of (A) Estrogen (B) Progesterone (C) Growth hormone (D) Oxytocin

Description : Young women are protected against myocardial infaracation because of the activity of (A) Estrogen (B) Progesterone (C) Growth hormone (D) Oxytocin

Last Answer : Answer : A

The hormone measured in urine to test pregnancy is (A) Anterior pituitary luteinizing hormone (B) Androgen (C) Progesterone (D) Choroinic gonadotropin

Description : The hormone measured in urine to test pregnancy is (A) Anterior pituitary luteinizing hormone (B) Androgen (C) Progesterone (D) Choroinic gonadotropin

Last Answer : Answer : D