Description : The most potent Vitamin D metabolite is (A) 25-Hydroxycholecalciferol (B) 1,25-Dihydroxycholecalciferol (C) 24, 25-Dihydroxycholecalciferol (D) 7-Dehydrocholesterol
Last Answer : (B) 1,25-Dihydroxycholecalciferol
Description : Calcitriol inhibits the conversion of (A) Cholesterol into 7-dehydrocholesterol (B) Cholecalciferol into 1-hydroxycholecalciferol (C) Cholecalciferol into 25-hydroxycholecalciferol (D) 25-Hydroxycholecalciferol into 1,25- dihydroxycholecalciferol
Last Answer : Answer : D
Description : The most active form of Vitamin D is (A) 25-Hydroxycholecalciferol (B) 1, 25-dihydroxycholecalciferol (C) 25-dihydroxyergocalciferol (D) None of these
Last Answer : Answer : A
Description : Parathormone is required for the conversion of (A) Cholecalciferol into 1-hydroxycholecalciferol (B) Cholecalciferol into 25-hydroxycholecalciferol (C) 25-Hydroxycholecalciferol into calcitriol (D) Cholesterol into 7-dehydrocholesterol
Last Answer : Answer : C
Description : A provitamin D synthesized in human beings is (A) Ergosterol (B) 7-Dehydrocholesterol (C) Cholecalciferol (D) 25-Hydroxycholecalciferol
Last Answer : Answer : B
Description : The structure shown below is of (A) Cholecalciferol (B) 25-Hydroxycholecalciferol (C) Ergocalciferol (D) 7-Dehydrocholesterol
Description : A metabolite which is common to pathways of cholesterol biosynthesis from acetyl-CoA and cholecalciferol formation from cholesterol is (A) Zymosterol (B) Lumisterol (C) Ergosterol (D) 7 Dehydrocholesterol
Description : The normal serum concentration of 24,25- dihydroxycholecalciferol in ng/ml is (A) 8–20 (B) 25–50 (C) 1–5 (D) 60–100
Description : The normal serum concentration of 1,25- dihydroxycholecalciferol in pg/ml is (A) 26–65 (B) 1–5 (C) 5–20 (D) 80–100
Description : Carbimazole differs from propylthiouracil in that: A. It is dose to dose less potent B. It has a shorter plasma half life C. It does not produce an active metabolite D. It does not inhibit peripheral conversion of thyroxine to triiodothyronine
Last Answer : D. It does not inhibit peripheral conversion of thyroxine to triiodothyronine
Description : Tubular reabsorption of calcium is increased by (A) Cholecalciferol (B) 25-Hydroxycholecalciferol (C) Calcitriol (D) All of these
Description : The normal serum concentration of 25-hydroxycholecalciferol in ng/ml is (A) 0–8 (B) 60–100 (C) 100–150 (D) 8–55
Description : Steroid hormones are synthesised from (A) Cholesterol (B) 7-Dehydrocholesterol (C) Calcitriol (D) 7-Hydroxycholesterol
Description : Provitamin D3 is (A) Cholecalciferol (B) Ergosterol (C) 7-Dehydrocholesterol (D) Ergocaliferol
Description : The β-ring of 7-dehydrocholesterol is cleaved to form cholecalciferol by (A) Infrared light (B) Dim light (C) Ultraviolet irridation with sunlight (D) Light of the tube lights
Description : This interferes with cholesterol absorption (A) Lipoprotein lipase (B) Creatinase (C) 7-dehydrocholesterol (D) β-sitosterol
Description : In renal rickets, the following hydroxylation of Vitamin D3 does not take place: (A) 25 (B) 1 (C) 24 (D) 7
Description : In retinal rickets, the following hydroxylation of Vitamin D3 does not take place: (A) 25 (B) 1 (C) 24 (D) 7
Description : Which of the vitamins is a potent antioxidant of Vitamin A? (A) Vitamin C (B) Vitamin E (C) Vitamin K (D) Vitamin D
Description : This vitamin is a potent antioxidant of vitamin A: (A) Vitamin C (B) Vitamin E (C) Vitamin K (D) Vitamin D
Description : Metformin is preferred over phenformin because: A. It is more potent B. It is less liable to cause lactic acidosis C. It does not interfere with vitamin B12 absorption D. It is not contraindicated in patients with kidney disease
Last Answer : B. It is less liable to cause lactic acidosis
Description : Methylmalonyl CoA is a metabolite of (A) Valine (B) Leucine (C) Isoleucine (D) All of these
Description : N-Formiminoglutamate is a metabolite of (A) Glutamate (B) Histidine (C) Tryptophan (D) Methionine
Description : The major metabolite of progesterone is (A) Pregnenolone (B) Pregnanediol (C) Estradiol (D) Norethindrone
Description : The chief metabolite of catecholamines is (A) Metanephrine (B) Normetanephrine (C) 3, 4-Dihydroxymandelic acid (D) Vanillylmandelic acid
Description : This abnormal metabolite may be responsible for the neurological manifestation of pernicious anemia. (A) Taurine (B) Methyl malonic acid (C) Xanthurenic acid (D) Phenyl pyruvic acid
Description : This abnormal metabolite may be responsible for the neurological manifestation of pernicious anemia: (A) Taurine (B) Methyl malonic acid (C) Xantherunic acid (D) Phenyl pyruvic acid
Description : At normal levels of creatinine in the blood, this metabolite is (A) Filtered at the glomerulus but not secreted nor reabsorbed by the tubule (B) Secreted by the tubule (C) Reabsorbed by the tubule (D) Secreted and reabsorbed by tubule
Description : Xanthuric acid is an abnormal metabolite of (A) Xanthine (B) Uric acid (C) Tyrosine (D) Tryptophan
Description : The metabolite which sustains urea cycle is (A) Ornithine (B) Citrulline (C) Carbamoyl phosphate (D) n-acetyl glutamate
Description : All the following statements about serotonin are true except (A) It causes vasolidatation (B) It causes bronchoconstriction (C) It is metabolized by monoamine oxidase (D) Its metabolite is 5-hydroxyindole acetic acid
Description : Pentagastrin is a (A) Naturally occurring form of gastrin (B) Inactive metabolite of gastrin (C) Active metabolite of gastrin (D) Synthetic form of gastrin
Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate
Last Answer : A
Description : The most potent hormone concerned with the retention of sodium in the body is (A) Cortisone (B) Aldosterone (C) Corticosterone (D) Cortisol
Description : One of the potent st imu lators of aldosterone secretion is (A) Increased sodium concentration (B) Decreased potassium concentration (C) Increased potassium concentration (D) Increased ECF volume
Description : A peptide which acts as potent smooth muscle hypotensive agent is (A) Glutathione (B) Bradykinin (C) Tryocidine (D) Gramicidin-s
Description : The normal concentration of vitamin A in blood in I.V/dl: (A) 20–55 (B) 24–60 (C) 30–65 (D) 35–70
Description : Is rubber a primary metabolite or a secondary metabolite? -Biology
Last Answer : answer:
Description : Which of the following is not an attribute of amlodipine ? (a) High and consistent oral bioavailability (b) Large volume of distribution (c) Generation of an active metabolite (d) Long elimination half-life
Last Answer : Ans: C
Description : Cefotaxime has the following properties except (a) It is highly active against aerobic gram negative bacteria (b) It is the most active cephalosporin against Pseudomonas aeruginosa (c) It produces an active metabolite (d) It has achieved high cure rates in serious hospital acquired infections
Last Answer : Ans: B
Description : Match the following. (A) Inhibitor of (i) Ricin catalytic activity (B) Possess peptide (ii) Malonate bonds (C) Cell wall material (iii)Chitin in fungi (D) Secondary (iv) Collagen metabolite Choose the correct option from the following: (A) ... iv) (ii) (c) (iii) (iv) (i) (ii) (d) (ii) (iii) (i) (iv)
Last Answer : (A) Inhibitor of (i) Ricin catalytic activity
Description : A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is (A) Fluvastatin (B) Cerivastatin (C) Lovastatin (D) Somatostatin
Last Answer : (C) Lovastatin
Description : Choose the correct statement about famciclovir: A. It is active against acyclovir resistant strains of herpes simplex virus B. It does not need conversion to an active metabolite C. It is used orally to treat genital herpes simplex D. It is the drug of choice for cytomegalovirus retinitis
Last Answer : C. It is used orally to treat genital herpes simplex
Description : The high virus selectivity of acyclovir is due to: A. Its preferential uptake by virus infected cells B. Need of virus specific enzyme for its conversion to the active metabolite C. Its action on ... reverse transcriptase which does not occur in noninfected cells D. Both A' and B' are correct
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : What is true of isonicotinic acid hydrazide (INH): A. An active transport mechanism concentrates INH inside sensitive mycobacteria B. Sensitive mycobacteria generate an active metabolite of INH through a catalaseperoxidase enzyme C. The most common mechanism of INH resistance is mutation i
Last Answer : D. Both 'A' and 'B' are correct
Description : Cefotaxime has the following properties except: A. It is highly active against aerobic gram negative bacteria B. It is the most active cephalosporin against Pseudomonas aeruginosa C. It produces an active metabolite D. It has achieved high cure rates in serious hospital acquired infections
Last Answer : B. It is the most active cephalosporin against Pseudomonas aeruginosa
Description : Which of the following is not an attribute of amlodipine: A. Generation of an active metabolite B. Large volume of distribution C. High and consistent oral bioavailability D. Long elimination half life
Last Answer : A. Generation of an active metabolit
Description : The following is true of procainamide except: A. It generates an active metabolite in the body B. Its plasma half-life is longer than that of quinidine C. On long-term use, it ... erythematosus like illness D. It is effective in many cases of ventricular extrasystoles, not responding to lignocaine
Last Answer : A. Disopyramide
Description : Norpethidine produced as a metabolite of pethidine is responsible for the following effect: A. Euphoria B. Excitement C. Analgesia D. Respiratory depression
Last Answer : B. Excitement
Description : The following is not true of morphine: A. Its 2-glucuronide metabolite is an active analgesic B. Its active metabolite penetrates blood-brain barrier better than morphine C. Its oral: parenteral activity ratio is 1:4 D. It undergoes enterohepatic cycling
Last Answer : B. Its active metabolite penetrates blood-brain barrier better than morphine