Gout is a metabolic disorder of catabolism of (A) Pyrimidine (B) Purine (C) Alanine (D) Phenylalanine

Gout is a metabolic disorder of catabolism of (A) Pyrimidine (B) Purine (C) Alanine (D) Phenylalanine
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Pyrimidine and purine nucleoside biosynthesis share a common precursor: (A) PRPP (B) Glycine (C) Fumarate (D) Alanine

Description : Pyrimidine and purine nucleoside biosynthesis share a common precursor: (A) PRPP (B) Glycine (C) Fumarate (D) Alanine

Last Answer : Answer : A

A 73 year old male presented with an acute attack of gout in his left knee. What is the most likely underlying metabolic cause? 1) decreased renal excretion of uric acid 2) endogenous overproduction of uric acid 3) excessive dietary purine intake 4) lactic acidosis 5) starvation

Description : A 73 year old male presented with an acute attack of gout in his left knee. What is the most likely underlying metabolic cause? 1) decreased renal excretion of uric acid 2) endogenous overproduction of uric acid 3) excessive dietary purine intake 4) lactic acidosis 5) starvation

Last Answer : Answers-1 The aetiology of gout can broadly be divided into cases where there is underexcretion of urate via the kidney (90%) or endogenous overproduction of uric acid (10%) although in practical ... diuretic use. Excessive dietary intake of purines is unlikely to be the main cause in this case.

The following coenzyme is required for catabolism of pyrimidine bases: (A) NADH (B) NADPH (C) FADH2 (D) None of these

Description : The following coenzyme is required for catabolism of pyrimidine bases: (A) NADH (B) NADPH (C) FADH2 (D) None of these

Last Answer : Answer : B

Uric acid is the end product of purine as well as protein catabolism in (A) Man (B) Fish (C) Birds (D) None of these

Description : Uric acid is the end product of purine as well as protein catabolism in (A) Man (B) Fish (C) Birds (D) None of these

Last Answer : Answer : C

The enzyme common to catabolism of all the purines is (A) Adenosine deaminase (B) Purine nucleoside phosphorylase (C) Guanase (D) None of these

Description : The enzyme common to catabolism of all the purines is (A) Adenosine deaminase (B) Purine nucleoside phosphorylase (C) Guanase (D) None of these

Last Answer : Answer : B

The end product of purine catabolism in man is (A) Inosine (B) Hypoxanthine (C) Xanthine (D) Uric acid

Description : The end product of purine catabolism in man is (A) Inosine (B) Hypoxanthine (C) Xanthine (D) Uric acid

Last Answer : Answer : D

In humans end product of purine catabolism is (A) Uric acid (B) Urea (C) Allantoin (D) Xanthine

Description : In humans end product of purine catabolism is (A) Uric acid (B) Urea (C) Allantoin (D) Xanthine

Last Answer : Answer : A

Catabolism of thymidylate gives (A) α-alanine (B) β-alanine (C) α-aminoisobutyrate (D) β-aminoisobutyrate

Description : Catabolism of thymidylate gives (A) α-alanine (B) β-alanine (C) α-aminoisobutyrate (D) β-aminoisobutyrate

Last Answer : Answer : D

β -Alanine is formed from catabolism of (A) Thymine (B) Thymine and cytosine (C) Thymine and uracil (D) Cytosine and uracil

Description : β -Alanine is formed from catabolism of (A) Thymine (B) Thymine and cytosine (C) Thymine and uracil (D) Cytosine and uracil

Last Answer : Answer : D

Thyroid hormones are synthesized by the iodination of the amino acid: (A) Glycine (B) Phenylalanine (C) Alanine (D) Tyrosine

Description : Thyroid hormones are synthesized by the iodination of the amino acid: (A) Glycine (B) Phenylalanine (C) Alanine (D) Tyrosine

Last Answer : Answer : D

The amino acid which synthesizes many hormornes: (A) Valine (B) Phenylalanine (C) Alanine (D) Histidine

Description : The amino acid which synthesizes many hormornes: (A) Valine (B) Phenylalanine (C) Alanine (D) Histidine

Last Answer : Answer : B

Which one of the following contributes nitrogen atoms to both purine and pyrimidine rings? (A) Aspartate (B) Carbanoyl phosphate (C) Carbondioxide (D) Tetrahydrofolate

Description : Which one of the following contributes nitrogen atoms to both purine and pyrimidine rings? (A) Aspartate (B) Carbanoyl phosphate (C) Carbondioxide (D) Tetrahydrofolate

Last Answer : Answer : A

Which one of the following causes frame shift mutation? (A) Transition (B) Transversion (C) Deletion (D) Substitution of purine to pyrimidine

Description : Which one of the following causes frame shift mutation? (A) Transition (B) Transversion (C) Deletion (D) Substitution of purine to pyrimidine

Last Answer : Answer : C

In DNA, genetic information is located in (A) Purine bases (B) Pyrimidine bases (C) Purine and pyrimidine bases (D) sugar

Description : In DNA, genetic information is located in (A) Purine bases (B) Pyrimidine bases (C) Purine and pyrimidine bases (D) sugar

Last Answer : Answer : C

The structural stability of the double helix of DNA is as cribbed largely to (A) Hydrogen bonding between adjacent purine bases (B) Hydrophobic bonding between staked purine and pyrinuidine nuclei (C) Hydrogen bonding between adjacent pyrimidine bases (E) Hydrogen bonding between purine and pyrimidine bases

Description : The structural stability of the double helix of DNA is as cribbed largely to (A) Hydrogen bonding between adjacent purine bases (B) Hydrophobic bonding between staked purine and ... Hydrogen bonding between adjacent pyrimidine bases (E) Hydrogen bonding between purine and pyrimidine bases

Last Answer : Answer : D

The available PRPP is used preferentially for (A) De novo synthesis of purine nucleotides (B) De novo synthesis of pyrimidine nucleotides (C) Salvage of purine bases (D) Salvage of pyrimidine bases

Description : The available PRPP is used preferentially for (A) De novo synthesis of purine nucleotides (B) De novo synthesis of pyrimidine nucleotides (C) Salvage of purine bases (D) Salvage of pyrimidine bases

Last Answer : Answer : C

5-Phosphoribosyl-1-pyrophosphate is required for the synthesis of (A) Purine nucleotides (B) Pyrimidine nucleotides (C) Both (A) and (B) (D) None of these

Description : 5-Phosphoribosyl-1-pyrophosphate is required for the synthesis of (A) Purine nucleotides (B) Pyrimidine nucleotides (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

Ultraviolet light can damage a DNA strand causing (A) Two adjacent purine residue to form a covalently bounded dimer (B) Two adjacent pyrimidine residues to form covalently bonded dimer (C) Disruption of phosphodiesterase linkage (D) Disruption of non-covalent linkage

Description : Ultraviolet light can damage a DNA strand causing (A) Two adjacent purine residue to form a covalently bounded dimer (B) Two adjacent pyrimidine residues to form covalently bonded dimer (C) Disruption of phosphodiesterase linkage (D) Disruption of non-covalent linkage

Last Answer : Answer : B

Genetic code is (A) Collection of codon (B) Collection of amino acids (C) Collection of purine nucleotide (D) Collection of pyrimidine nucleotide

Description : Genetic code is (A) Collection of codon (B) Collection of amino acids (C) Collection of purine nucleotide (D) Collection of pyrimidine nucleotide

Last Answer : Answer : A

Intestinal nucleosidases act on nucleosides and produce (A) Purine base only (B) Phosphate only (C) Sugar only (D) Purine or pyrimidine bases and sugars

Description : Intestinal nucleosidases act on nucleosides and produce (A) Purine base only (B) Phosphate only (C) Sugar only (D) Purine or pyrimidine bases and sugars

Last Answer : Answer : D

In RNA molecule guanine content does not necessarily equal its cytosine content nor does its adenine content necessarily equal its uracil content since it is a (A) Single strand molecule (B) Double stranded molecule (C) Double stranded helical molecule (D) Polymer of purine and pyrimidine ribonucleotides

Description : In RNA molecule guanine content does not necessarily equal its cytosine content nor does its adenine content necessarily equal its uracil content since it is a (A) Single strand molecule ( ... stranded molecule (C) Double stranded helical molecule (D) Polymer of purine and pyrimidine ribonucleotides

Last Answer : Answer : A

A nucleotide consists of (A) A nitrogenous base like choline (B) Purine + pyrimidine base + sugar + phosphorous (C) Purine or pyrimidine base + sugar (D) Purine or pyrimidine base + phosphorous

Description : A nucleotide consists of (A) A nitrogenous base like choline (B) Purine + pyrimidine base + sugar + phosphorous (C) Purine or pyrimidine base + sugar (D) Purine or pyrimidine base + phosphorous

Last Answer : Answer : B

A nucleoside consists of (A) Nitrogenous base (B) Purine or pyrimidine base + sugar (C) Purine or pyrimidine base + phosphorous (D) Purine + pyrimidine base + sugar + phosphorous

Description : A nucleoside consists of (A) Nitrogenous base (B) Purine or pyrimidine base + sugar (C) Purine or pyrimidine base + phosphorous (D) Purine + pyrimidine base + sugar + phosphorous

Last Answer : Answer : B

Which one of the following causes frame shift mutation? (A) Transition (B) Transversion (C) Deletion (D) Substitution of purine to pyrimidine

Description : Which one of the following causes frame shift mutation? (A) Transition (B) Transversion (C) Deletion (D) Substitution of purine to pyrimidine

Last Answer : Answer : C

All mammalian steroid hormones are formed from (A) Purine (B) Pyrimidine (C) Cholesterol (D) Pyrrole

Description : All mammalian steroid hormones are formed from (A) Purine (B) Pyrimidine (C) Cholesterol (D) Pyrrole

Last Answer : Answer : C

Thiamine is (A) Water-soluble vitamin (B) Fat soluble vitamin (C) Purine base (D) Pyrimidine base

Description : Thiamine is (A) Water-soluble vitamin (B) Fat soluble vitamin (C) Purine base (D) Pyrimidine base

Last Answer : Answer : D

Thymine is (A) Water soluble vitamin (B) Fat soluble vitamin (C) Purine base (D) Pyrimidine base

Description : Thymine is (A) Water soluble vitamin (B) Fat soluble vitamin (C) Purine base (D) Pyrimidine base

Last Answer : Answer : D

Vitamin B12 has a complex ring structure (corrin ring) consisting of four (A) Purine rings (B) Pyrimidine rings (C) Pyrrole rings (D) Pteridine rings

Description : Vitamin B12 has a complex ring structure (corrin ring) consisting of four (A) Purine rings (B) Pyrimidine rings (C) Pyrrole rings (D) Pteridine rings

Last Answer : Answer : C

Which of the following contributes nitrogen atoms to both purine and pyrimidine rings? (A) Aspartate (B) Carbamoyl phosphate (C) CO2 (D) Glutamine

Description : Which of the following contributes nitrogen atoms to both purine and pyrimidine rings? (A) Aspartate (B) Carbamoyl phosphate (C) CO2 (D) Glutamine

Last Answer : Answer : A

Mammals other than higher primates do not suffer from gout because they (A) Lack xanthine oxidase (B) Lack adenosine deaminase (C) Lack purine nucleoside phosphorylase (D) Possess uricase

Description : Mammals other than higher primates do not suffer from gout because they (A) Lack xanthine oxidase (B) Lack adenosine deaminase (C) Lack purine nucleoside phosphorylase (D) Possess uricase

Last Answer : Answer : D

Inherited deficiency of purine nucleoside phosphorylase causes (A) Dwarfism (B) Mental retardation (C) Immunodeficiency (D) Gout

Description : Inherited deficiency of purine nucleoside phosphorylase causes (A) Dwarfism (B) Mental retardation (C) Immunodeficiency (D) Gout

Last Answer : Answer : C

Which of the following is associated with Hyperuricaemia? 1) is usually due to an excess purine consumption 2) occurs in association with acute lymphoblastic leukaemia 3) in primary gout is inherited in an autosomal dominant manner 4) can be reduced with low dose aspirin therapy 5) can be treated with uricosuric drugs even in renal failure

Description : Which of the following is associated with Hyperuricaemia? 1) is usually due to an excess purine consumption 2) occurs in association with acute lymphoblastic leukaemia 3) in primary gout is inherited in ... with low dose aspirin therapy 5) can be treated with uricosuric drugs even in renal failure

Last Answer : Answers-2 Hyperuricaemia may be due to increased purine intake, urate production or reduced urate clearance, and is most commonly due to the latter. Therefore it can occur in association with enhanced ... . Many of the uricosuric drugs may be detrimental in renal failure and may not be effective.

In purine nucleus nitrogen atom at 1 position is derived from (A) Aspartate (B) Glutamate (C) Glycine (D) Alanine

Description : In purine nucleus nitrogen atom at 1 position is derived from (A) Aspartate (B) Glutamate (C) Glycine (D) Alanine

Last Answer : Answer : A

In purine biosynthesis carbon atoms at 4 and 5 position and N at 7 position are contributed by (A) Glycine (B) Glutamine (C) Alanine (D) Threonine

Description : In purine biosynthesis carbon atoms at 4 and 5 position and N at 7 position are contributed by (A) Glycine (B) Glutamine (C) Alanine (D) Threonine

Last Answer : Answer : A

In humans, the principal metabolic product of pyrimidines is (A) Uric acid (B) Allantoin (C) Hypoxanthine (D) β-alanine

Description : In humans, the principal metabolic product of pyrimidines is (A) Uric acid (B) Allantoin (C) Hypoxanthine (D) β-alanine

Last Answer : Answer : D

Difference between purine and pyrimidine. -Biology

Description : Difference between purine and pyrimidine. -Biology

Last Answer : answer:

Assertion: Uric acid is produced by the metabolism of purine and pyrimidine. Reason: Uric acid has high toxicity and is soluble in water.

Description : Assertion: Uric acid is produced by the metabolism of purine and pyrimidine. Reason: Uric acid has high toxicity and is soluble in water.

Last Answer : Assertion: Uric acid is produced by the metabolism of purine and pyrimidine. Reason: Uric acid has ... D. If both Assertion and Reason are false

True statements about the nucleic acid include: a. contains purine and pyrimidine which are bound together by covalent bonds b. there is always an equal concentration of purine and pyrimidine c. in RNA, thymine is replaced by uracil d. introns is more common than exons on the DNA e. the histones mark the excision site

Description : True statements about the nucleic acid include: a. contains purine and pyrimidine which are bound together by covalent bonds b. there is always an equal concentration of purine and pyrimidine c. in RNA, ... d. introns is more common than exons on the DNA e. the histones mark the excision site

Last Answer : there is always an equal concentration of purine and pyrimidine

n the DNA molecule, (a) the proportion of adenine in relation to thymine varies with the organism (b) there are two strands which run anti- parallel-one in 5′ → 3′ direction and other in 3′ → 5′ (c) the total amount of purine nucleotides and pyrimidine nucleotides is not always equal (d) there are two strands which run parallel in the 5′ → 3′ direction.

Description : n the DNA molecule, (a) the proportion of adenine in relation to thymine varies with the organism (b) there are two strands which run anti- parallel-one in 5′ → 3′ direction and other in 3′ → ... is not always equal (d) there are two strands which run parallel in the 5′ → 3′ direction.

Last Answer : (b) there are two strands which run anti- parallel-one in 5′ → 3′ direction and other in 3′ → 5′

A nucleotide is formed of (a) purine, pyrimidine and phosphate (b) purine, sugar and phosphate (c) nitrogen base, sugar and phosphate (d) pyrimidine, sugar and phosphate

Description : A nucleotide is formed of (a) purine, pyrimidine and phosphate (b) purine, sugar and phosphate (c) nitrogen base, sugar and phosphate (d) pyrimidine, sugar and phosphate

Last Answer : (c) nitrogen base, sugar and phosphate

Adenine is (a) purine (b) pyrimidine (c) nucleoside (d) nucleotide.

Description : Adenine is (a) purine (b) pyrimidine (c) nucleoside (d) nucleotide.

Last Answer : (a) purine

Uridine, present only in RNA is a (a) nucleoside (b) nucleotide (c) purine (d) pyrimidine.

Description : Uridine, present only in RNA is a (a) nucleoside (b) nucleotide (c) purine (d) pyrimidine.

Last Answer : a) nucleoside

Alkylating agents exert cytotoxic action by inducing: A. Breakage of DNA strand B. Cross linking of DNA strands C. Abnormal pairing of purine and pyrimidine bases D. All of the above

Description : Alkylating agents exert cytotoxic action by inducing: A. Breakage of DNA strand B. Cross linking of DNA strands C. Abnormal pairing of purine and pyrimidine bases D. All of the above

Last Answer : D. All of the above

61. A client with gout asks the nurse what food must be avoided so that the family can provide support. Which food has the highest in purine content and must be excluded from the dietary plan?

Description : 61. A client with gout asks the nurse what food must be avoided so that the family can provide support. Which food has the highest in purine content and must be excluded from the dietary plan?

Last Answer : D. Liver

In contrast to a patient undergoing an elective operation, which of the following statement(s) is/are true concerning a patient who has suffered a multiple trauma? a. Basal metabolic rates are similar b. The patient is highly sensitive to insulin c. Utilization of the amino acids, glutamine and alanine, is similar to their composition in skeletal muscle d. Fat and protein stores are rapidly depleted

Description : In contrast to a patient undergoing an elective operation, which of the following statement(s) is/are true concerning a patient who has suffered a multiple trauma? a. Basal metabolic rates are ... is similar to their composition in skeletal muscle d. Fat and protein stores are rapidly depleted

Last Answer : Answer: b, d The degree of hypermetabolism is generally related to the severity of injury. Patients with long-bone fractures have a 15-25% increase in metabolic rate, whereas metabolic ... in injured subjects, if unfed, severely injured patients rapidly deplete their fat and protein stores

Select the correct statement regarding the specific disorder of muscular or skeletal system. (a) Muscular dystrophy – Age related shortening of muscles (b) Osteoporosis – Decrease in bone mass and higher chances of fractures with advancing age (c) Myasthenia gravis – Autoimmune disorder which inhibits sliding of myosin filaments (d) Gout – Inflammation of joints due to extra deposition of calcium

Description : Select the correct statement regarding the specific disorder of muscular or skeletal system. (a) Muscular dystrophy - Age related shortening of muscles (b) Osteoporosis - Decrease in bone mass and ... of myosin filaments (d) Gout - Inflammation of joints due to extra deposition of calcium

Last Answer : (b) Osteoporosis – Decrease in bone mass and higher chances of fractures with advancing age

Assertion `:-` Analysis of urine helps in clinical diagnosis of many metabolic disorder. ltbr. Reason `:-` Glycosuria is indicative of disabetes insip

Description : Assertion `:-` Analysis of urine helps in clinical diagnosis of many metabolic disorder. ltbr. Reason `:-` Glycosuria is indicative of disabetes insip

Last Answer : Assertion `:-` Analysis of urine helps in clinical diagnosis of many metabolic disorder. ltbr. Reason `: ... D. If both Assertion & Reason are false.

A health disorder that results from the deficiency of thyroxine in adults and is characterized by (i) a low metabolic rate, (ii) increase in body weig

Description : A health disorder that results from the deficiency of thyroxine in adults and is characterized by (i) a low metabolic rate, (ii) increase in body weig

Last Answer : A health disorder that results from the deficiency of thyroxine in adults and is characterized by ( ... B. Myxedema C. Simple goiter D. Hypothyroidism

Where can I find a list of metabolic disorder symptoms?

Description : Where can I find a list of metabolic disorder symptoms?

Last Answer : Go to www.localhealth.com/article/metabolic-disorders. This has a great article on what the disorder is and what symptoms you should look out for. Some symptoms include breathing problems, organ failure, and seizure. This article will give you all the insight you need.

Haemophilia is – (1) an organic disorder (2) a metabolic disorder (3) a genetic disorder (4) a hormonal disorder

Description : Haemophilia is – (1) an organic disorder (2) a metabolic disorder (3) a genetic disorder (4) a hormonal disorder

Last Answer : (3) a genetic disorder Explanation: Haemophilia is a group of hereditary genetic disorders that impair the body's ability to control blood clotting or coagulation, which is used to stop bleeding when a blood ... the most common form of the disorder, present in about 1 in 5,00010,000 male births.