Assertion: Uric acid is produced by the metabolism of purine and pyrimidine. Reason: Uric acid has high toxicity and is soluble in water.

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Assertion: Uric acid is produced by the metabolism of purine and pyrimidine. Reason: Uric acid has ... D. If both Assertion and Reason are false

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Description : Thiamine is (A) Water-soluble vitamin (B) Fat soluble vitamin (C) Purine base (D) Pyrimidine base

Last Answer : Answer : D

Description : Thymine is (A) Water soluble vitamin (B) Fat soluble vitamin (C) Purine base (D) Pyrimidine base

Last Answer : Answer : D

Description : True statements about the nucleic acid include: a. contains purine and pyrimidine which are bound together by covalent bonds b. there is always an equal concentration of purine and pyrimidine c. in RNA, ... d. introns is more common than exons on the DNA e. the histones mark the excision site

Last Answer : there is always an equal concentration of purine and pyrimidine

Description : In inherited deficiency of hypoxanthine guanine phosphoribosyl transferase (A) De novo synthesis of purine nucleotides is decreased (B) Salvage of purines is decreased (C) Salvage of purines is increased (D) Synthesis of uric acid is decreased

Last Answer : Answer : B

Description : Uric acid is the end product of purine as well as protein catabolism in (A) Man (B) Fish (C) Birds (D) None of these

Last Answer : Answer : C

Description : The end product of purine catabolism in man is (A) Inosine (B) Hypoxanthine (C) Xanthine (D) Uric acid

Last Answer : Answer : D

Description : In humans purine are catabolised to uric acid due to lack of the enzyme: (A) Urease (B) Uricase (C) Xanthine oxidase (D) Guanase

Last Answer : Answer : B

Description : In humans end product of purine catabolism is (A) Uric acid (B) Urea (C) Allantoin (D) Xanthine

Last Answer : Answer : A

Description : A 73 year old male presented with an acute attack of gout in his left knee. What is the most likely underlying metabolic cause? 1) decreased renal excretion of uric acid 2) endogenous overproduction of uric acid 3) excessive dietary purine intake 4) lactic acidosis 5) starvation

Last Answer : Answers-1 The aetiology of gout can broadly be divided into cases where there is underexcretion of urate via the kidney (90%) or endogenous overproduction of uric acid (10%) although in practical ... diuretic use. Excessive dietary intake of purines is unlikely to be the main cause in this case.

Description : Assertion `:-` Uricotelism is terrestrial adaptation. Reason `:-` Uric acid is least toxic and can be removed with a minimum loss of water.

Last Answer : Assertion `:-` Uricotelism is terrestrial adaptation. Reason `:-` Uric acid is least toxic and can be ... . D. If both Assertion & Reason are false.

Description : Difference between purine and pyrimidine. -Biology

Last Answer : answer:

Description : Which one of the following contributes nitrogen atoms to both purine and pyrimidine rings? (A) Aspartate (B) Carbanoyl phosphate (C) Carbondioxide (D) Tetrahydrofolate

Last Answer : Answer : A

Description : Which one of the following causes frame shift mutation? (A) Transition (B) Transversion (C) Deletion (D) Substitution of purine to pyrimidine

Last Answer : Answer : C

Description : In DNA, genetic information is located in (A) Purine bases (B) Pyrimidine bases (C) Purine and pyrimidine bases (D) sugar

Last Answer : Answer : C

Description : The structural stability of the double helix of DNA is as cribbed largely to (A) Hydrogen bonding between adjacent purine bases (B) Hydrophobic bonding between staked purine and ... Hydrogen bonding between adjacent pyrimidine bases (E) Hydrogen bonding between purine and pyrimidine bases

Last Answer : Answer : D

Description : The available PRPP is used preferentially for (A) De novo synthesis of purine nucleotides (B) De novo synthesis of pyrimidine nucleotides (C) Salvage of purine bases (D) Salvage of pyrimidine bases

Last Answer : Answer : C

Description : 5-Phosphoribosyl-1-pyrophosphate is required for the synthesis of (A) Purine nucleotides (B) Pyrimidine nucleotides (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

Description : Ultraviolet light can damage a DNA strand causing (A) Two adjacent purine residue to form a covalently bounded dimer (B) Two adjacent pyrimidine residues to form covalently bonded dimer (C) Disruption of phosphodiesterase linkage (D) Disruption of non-covalent linkage

Last Answer : Answer : B

Description : Genetic code is (A) Collection of codon (B) Collection of amino acids (C) Collection of purine nucleotide (D) Collection of pyrimidine nucleotide

Last Answer : Answer : A

Description : Gout is a metabolic disorder of catabolism of (A) Pyrimidine (B) Purine (C) Alanine (D) Phenylalanine

Last Answer : Answer : B

Description : Pyrimidine and purine nucleoside biosynthesis share a common precursor: (A) PRPP (B) Glycine (C) Fumarate (D) Alanine

Last Answer : Answer : A

Description : Intestinal nucleosidases act on nucleosides and produce (A) Purine base only (B) Phosphate only (C) Sugar only (D) Purine or pyrimidine bases and sugars

Last Answer : Answer : D

Description : In RNA molecule guanine content does not necessarily equal its cytosine content nor does its adenine content necessarily equal its uracil content since it is a (A) Single strand molecule ( ... stranded molecule (C) Double stranded helical molecule (D) Polymer of purine and pyrimidine ribonucleotides

Last Answer : Answer : A

Description : A nucleotide consists of (A) A nitrogenous base like choline (B) Purine + pyrimidine base + sugar + phosphorous (C) Purine or pyrimidine base + sugar (D) Purine or pyrimidine base + phosphorous

Last Answer : Answer : B

Description : A nucleoside consists of (A) Nitrogenous base (B) Purine or pyrimidine base + sugar (C) Purine or pyrimidine base + phosphorous (D) Purine + pyrimidine base + sugar + phosphorous

Last Answer : Answer : B

Description : Which one of the following causes frame shift mutation? (A) Transition (B) Transversion (C) Deletion (D) Substitution of purine to pyrimidine

Last Answer : Answer : C

Description : All mammalian steroid hormones are formed from (A) Purine (B) Pyrimidine (C) Cholesterol (D) Pyrrole

Last Answer : Answer : C

Description : Vitamin B12 has a complex ring structure (corrin ring) consisting of four (A) Purine rings (B) Pyrimidine rings (C) Pyrrole rings (D) Pteridine rings

Last Answer : Answer : C

Description : Which of the following contributes nitrogen atoms to both purine and pyrimidine rings? (A) Aspartate (B) Carbamoyl phosphate (C) CO2 (D) Glutamine

Last Answer : Answer : A

Description : n the DNA molecule, (a) the proportion of adenine in relation to thymine varies with the organism (b) there are two strands which run anti- parallel-one in 5′ → 3′ direction and other in 3′ → ... is not always equal (d) there are two strands which run parallel in the 5′ → 3′ direction.

Last Answer : (b) there are two strands which run anti- parallel-one in 5′ → 3′ direction and other in 3′ → 5′

Description : A nucleotide is formed of (a) purine, pyrimidine and phosphate (b) purine, sugar and phosphate (c) nitrogen base, sugar and phosphate (d) pyrimidine, sugar and phosphate

Last Answer : (c) nitrogen base, sugar and phosphate

Description : Adenine is (a) purine (b) pyrimidine (c) nucleoside (d) nucleotide.

Last Answer : (a) purine

Description : Uridine, present only in RNA is a (a) nucleoside (b) nucleotide (c) purine (d) pyrimidine.

Last Answer : a) nucleoside

Description : Alkylating agents exert cytotoxic action by inducing: A. Breakage of DNA strand B. Cross linking of DNA strands C. Abnormal pairing of purine and pyrimidine bases D. All of the above

Last Answer : D. All of the above

Description : All of the following statements about uric acid are true except (A) It is a catabolite of purines (B) It is excreted by the kidneys (C) It is undissociated at pH above 5.8 (D) It is less soluble than sodium urate

Last Answer : Answer : C

Description : The end product of amino acid nitrogen metabolism in uricotelic organisms (reptiles and birds) is (A) Bilirubin (B) Urea (C) Uric acid (D) Biliverdin

Last Answer : Answer : C

Description : The major end product of protein nitrogen metabolism in man is (A) Glycine (B) Uric acid (C) Urea (D) NH3

Last Answer : Answer : C

Description : Choose the correct statement about paracetamol: A. It increases uric acid excretion B. It is the most common drug implicated in causing analgesic nephropathy C. In equianalgesic doses it is safer than aspirin D. It stimulates cellular metabolism

Last Answer : C. In equianalgesic doses it is safer than aspirin

Description : Assertion : Insulin is not given orally. Reason : Insulin hormone is lipid-soluble and directily enters inside the cell membrane.

Last Answer : Assertion : Insulin is not given orally. Reason : Insulin hormone is lipid-soluble and directily enters ... D. If both Assertion and Reason are false.

Description : Assertion(A): Ethyl alcohol is soluble in organic solvents Reason (R): Ethyl alcohol is having non polar ethyl group

Last Answer : Assertion(A): Ethyl alcohol is soluble in organic solvents Reason (R): Ethyl alcohol is having non polar ... is false D. A is false but R is true

Description : Assertion (A): Ethyl alcohol is soluble in organic solvents Reason(R): Calcium chloride can form an addition compound with ethyl alcohol

Last Answer : Assertion (A): Ethyl alcohol is soluble in organic solvents Reason(R): Calcium chloride can form an addition ... is false D. A is false but R is true

Description : Assertion `:` Vitamins are essential for healthyl life. Reason `:` Vitamins regulate metabolism

Last Answer : Assertion `:` Vitamins are essential for healthyl life. Reason `:` Vitamins regulate metabolism A. If ... D. If both Assertion & Reason are false.

Description : Bioavailability differences among oral formulations of a drug are most likely to occur if the drug: A. Is freely water soluble B. Is completely absorbed C. Is incompletely absorbed D. Undergoes little first-pass metabolism

Last Answer : C. Is incompletely absorbed

Description : Bioavailability differences among oral formulations of a drug are most likely to occur if the drug: A. Is freely water soluble B. Is completely absorbed C. Is incompletely absorbed D. Undergoes little first-pass metabolism

Last Answer : C. Is incompletely absorbed

Description : Uric acid is produced by the breakdown of

Last Answer : Uric acid is produced by the breakdown of A. Proteins B. Amino acids C. Nucleic acids D. Starch

Description : If therapy with multiple drugs causes induction of drug metabolism in your asthma patient, it will (a) Result in increased smooth endoplasmic reticulum (b) Result in increased rough endoplasmic reticulum ... soluble cytoplasmic fraction (d) Require 3-4 months to reach completion (e) Be irreversible

Last Answer : Ans: A

Description : 5 A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination ... : A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution

Last Answer : D. Redistribution

Description : A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination of ... : A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution

Last Answer : D. Redistribution

Description : A nonvolatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination of ... : A. Metabolism in liver B. Plasma protein binding C. Excretion by kidney D. Redistribution

Last Answer : D. Redistribution

Description : Folinic acid is specifically indicated for: A. Prophylaxis of neural tube defect in the offspring of women receiving anticonvulsant medication B. Counteracting toxicity of high dose methotrexate C. Pernicious anaemia D. Anaemia associated with renal failure

Last Answer : C. Pernicious anaemia