The function of a repressor protein in an operon system is to prevent synthesis by binding to (A) The ribosome (B) A specific region of the operon preventing transcription of structural genes (C) The RNA polymerase (D) A specific region of the mRNA preventing translation to protein

The function of a repressor protein in an operon system is to prevent synthesis by binding to (A) The ribosome (B) A specific region of the operon preventing transcription of structural genes (C) The RNA polymerase (D) A specific region of the mRNA preventing translation to protein
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Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) Attaching to promoter region and facilitating the binding of RNA polymerase holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus

Description : Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) ... holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus

Last Answer : Answer : D

Which one of the following is wrongly matched? (a) Transcription - Writing information from DNA to tRNA. (b) Translation - Using information in mRNA to make protein. (c) Repressor protein - Binds to operator to stop enzyme synthesis. (d) Operon - Structural genes, operator and promoter.

Description : Which one of the following is wrongly matched? (a) Transcription - Writing information from DNA to tRNA. (b) Translation - Using information in mRNA to make protein. (c) Repressor protein - Binds to operator to stop enzyme synthesis. (d) Operon - Structural genes, operator and promoter.

Last Answer : (c) Repressor protein - Binds to operator to stop enzyme synthesis.

Which one of the following is wrongly matched? (a) Transcription - Writing information from DNA to tRNA. (b) Translation - Using information in mRNA to make protein. (c) Repressor protein - Binds to operator to stop enzyme synthesis. (d) Operon - Structural genes, operator and promoter.

Description : Which one of the following is wrongly matched? (a) Transcription - Writing information from DNA to tRNA. (b) Translation - Using information in mRNA to make protein. (c) Repressor protein - Binds to operator to stop enzyme synthesis. (d) Operon - Structural genes, operator and promoter.

Last Answer : (d) Operon - Structural genes, operator and promoter

Transcription of structural genes of lac operon is prevented by binding of the repressor tetramer to (A) i gene (B) Operator locus (C) Promoter (D) z gene

Description : Transcription of structural genes of lac operon is prevented by binding of the repressor tetramer to (A) i gene (B) Operator locus (C) Promoter (D) z gene

Last Answer : Answer : B

Select the incorrect statement out of the five given below about lac operon when Lactose is present in the medium. a) Gene – A gets transcribed into mRNA which produces β-galactoside permease b) Inducer-Repressor complex is formed c) Lactose inactivates repressor protein d) RNA polymerase transcribe Z-gene, Y-gene and A-gene e) Allolactose is the inducer of lac operon

Description : Select the incorrect statement out of the five given below about lac operon when Lactose is present in the medium. a) Gene - A gets transcribed into mRNA which produces β-galactoside permease b) ... polymerase transcribe Z-gene, Y-gene and A-gene e) Allolactose is the inducer of lac operon

Last Answer : Gene – A gets transcribed into mRNA which produces β-galactoside permease b) Inducer-Repressor complex is formed

The ‘rho’ (ρ) factor is involved (A) To increase the rate of RNA synthesis (B) In binding catabolite repressor to the promoter region (C) In proper termination of transcription (D) To allow proper initiation of transcriptide

Description : The ‘rho’ (ρ) factor is involved (A) To increase the rate of RNA synthesis (B) In binding catabolite repressor to the promoter region (C) In proper termination of transcription (D) To allow proper initiation of transcriptide

Last Answer : Answer : C

Chloramphenicol inhibits bacterial protein synthesis by: A. Binding to 30S ribosome and inhibiting attachment of aminoacyl tRNA B. Binding to 50S ribosome and preventing peptide bond formation C. Binding to 50S ribosome and blocking translocation of peptide chain D. Binding to both 30S and 50S ribosome and inducing misreading of mRNA code

Description : Chloramphenicol inhibits bacterial protein synthesis by: A. Binding to 30S ribosome and inhibiting attachment of aminoacyl tRNA B. Binding to 50S ribosome and preventing peptide bond formation C. Binding to ... chain D. Binding to both 30S and 50S ribosome and inducing misreading of mRNA code

Last Answer : B. Binding to 50S ribosome and preventing peptide bond formation

Binding of RNA polymerase holoenzyme to the promoter region of lac operon is facilitated by (A) Catabolite gene activator protein (CAP) (B) cAMP (C) CAP-cAMP complex (D) None of these

Description : Binding of RNA polymerase holoenzyme to the promoter region of lac operon is facilitated by (A) Catabolite gene activator protein (CAP) (B) cAMP (C) CAP-cAMP complex (D) None of these

Last Answer : Answer : C

Negative regulation of protein synthesis is accomplished by A- allosteric inhibition B- the binding of RNA polymerase to the promoter C- the binding of a repressor to the DNA D- the binding of a repressor to the RNA polymerase

Description : Negative regulation of protein synthesis is accomplished by A- allosteric inhibition B- the binding of RNA polymerase to the promoter C- the binding of a repressor to the DNA D- the binding of a repressor to the RNA polymerase

Last Answer : the binding of a repressor to the DNA

The regulatory i gene of lac operon (A) Is inhibited by lacotse (B) Is inhibited by its own product, the repressor protein (C) Forms a regulatory protein which increases the expression of downstream structural genes (D) Is constitutively expressed

Description : The regulatory i gene of lac operon (A) Is inhibited by lacotse (B) Is inhibited by its own product, the repressor protein (C) Forms a regulatory protein which increases the expression of downstream structural genes (D) Is constitutively expressed

Last Answer : Answer : D

An important step in protein synthesis is transcription. Which of the following statement(s) is/are true concerning this process? a. The first step in gene transcription involves separating the double helix of DNA by an enzyme known as DNA polymerase b. The initial product of DNA transcription is called heterogeneous nuclear RNA which codes directly for proteins c. After processing is complete, the mRNA is exported from the nucleus to the cytoplasm d. Only one protein can be produced from an initial mRNA strand

Description : An important step in protein synthesis is transcription. Which of the following statement(s) is/are true concerning this process? a. The first step in gene transcription involves separating the double helix ... nucleus to the cytoplasm d. Only one protein can be produced from an initial mRNA strand

Last Answer : Answer: c Transcription of a gene begins at an initiation site associated with a specific DNA sequence, termed a promoter region. After binding to DNA, the RNA polymerase opens up a short ... different proteins from the same gene. mRNA is exported from the nucleus only after processing is complete

Expression of structural genes of lac operon is affected by all the following except (A) Lactose or its analogues (B) Repressor tetramer (C) cAMP (D) CAP-cAMP complex

Description : Expression of structural genes of lac operon is affected by all the following except (A) Lactose or its analogues (B) Repressor tetramer (C) cAMP (D) CAP-cAMP complex

Last Answer : Answer : C

The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Description : The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Last Answer : .is located immediately upstream of the start codon

The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Description : The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Last Answer : .is located immediately upstream of the start codon

All of the following statements about eukaryotic promoters are true except (A) They may be located upstream or down stream from the structural gene (B) They have two consensus sequences (C) One consensus sequence binds RNA polymerase (D) Mutations in promoter region can decrease the efficiency of transcription of the structural gene

Description : All of the following statements about eukaryotic promoters are true except (A) They may be located upstream or down stream from the structural gene (B) They have two consensus sequences ( ... (D) Mutations in promoter region can decrease the efficiency of transcription of the structural gene

Last Answer : Answer : A

In the process of transcription in bacterial cells (A) Initiation requires rho protein (B) RNA polymerase incorporates methylated bases in correct sequence (C) Both the sigma unit and core enzymes of RNA polymerase are required for accurate promotor site binding (D) Primase is necessary for initiation

Description : In the process of transcription in bacterial cells (A) Initiation requires rho protein (B) RNA polymerase incorporates methylated bases in correct sequence (C) Both the sigma unit and core ... RNA polymerase are required for accurate promotor site binding (D) Primase is necessary for initiation

Last Answer : Answer : C

The RNA that pick up specific amino acid from amino acid pool in the cytoplasm to ribosome during protein synthesis is called (a) rRNA (b) RNA (c) mRNA (d) tRNA.

Description : The RNA that pick up specific amino acid from amino acid pool in the cytoplasm to ribosome during protein synthesis is called (a) rRNA (b) RNA (c) mRNA (d) tRNA.

Last Answer : a) rRNA

The RNA that pick up specific amino acid from amino acid pool in the cytoplasm to ribosome during protein synthesis is called (a) rRNA (b) RNA (c) mRNA (d) tRNA

Description : The RNA that pick up specific amino acid from amino acid pool in the cytoplasm to ribosome during protein synthesis is called (a) rRNA (b) RNA (c) mRNA (d) tRNA

Last Answer : tRNA

.Gene regulation governing lactose operon of E.coli that involves the lac I gene product is (a) negative and repressible because repressor protein prevents transcription (b) feedback inhibition because excess of β-galactosidase can switch off transcription (c) positive and inducible because it can be induced by lactose (d) negative and inducible because repressor protein prevents transcription.

Description : .Gene regulation governing lactose operon of E.coli that involves the lac I gene product is (a) negative and repressible because repressor protein prevents transcription (b) feedback inhibition ... be induced by lactose (d) negative and inducible because repressor protein prevents transcription.

Last Answer : (d) negative and inducible because repressor protein prevents transcription.

Gene regulation governing lactose operon of E.coli that involves the lac I gene product is (a) negative and repressible because repressor protein prevents transcription (b) feedback inhibition because excess of β-galactosidase can switch off transcription (c) positive and inducible because it can be induced by lactose (d) negative and inducible because repressor protein prevents transcription.

Description : Gene regulation governing lactose operon of E.coli that involves the lac I gene product is (a) negative and repressible because repressor protein prevents transcription (b) feedback inhibition ... be induced by lactose (d) negative and inducible because repressor protein prevents transcription.

Last Answer : (d) negative and inducible because repressor protein prevents transcription.

The process of translation is (a) ribosome synthesis (b) protein synthesis (c) DNA synthesis (d) RNA synthesis.

Description : The process of translation is (a) ribosome synthesis (b) protein synthesis (c) DNA synthesis (d) RNA synthesis.

Last Answer : (c) DNA synthesis

The process of translation is (a) ribosome synthesis (b) protein synthesis (c) DNA synthesis (d) RNA synthesis

Description : The process of translation is (a) ribosome synthesis (b) protein synthesis (c) DNA synthesis (d) RNA synthesis

Last Answer : (b) protein synthesis

Tetracylin prevents synthesis of polypeptide by (A) Blocking mRNA formation from DNA (B) Releasing peptides from mRNA-tRNA complex (C) Competing with mRNA for ribosomal binding sites (D) Preventing binding of aminoacyl tRNA

Description : Tetracylin prevents synthesis of polypeptide by (A) Blocking mRNA formation from DNA (B) Releasing peptides from mRNA-tRNA complex (C) Competing with mRNA for ribosomal binding sites (D) Preventing binding of aminoacyl tRNA

Last Answer : Answer : D

Mutations in promoter regions of genes can cause (A) Premature termination of translation (B) Change in reading frame of downstream structural gene (C) Decreased efficiency of transcription (D) All of these

Description : Mutations in promoter regions of genes can cause (A) Premature termination of translation (B) Change in reading frame of downstream structural gene (C) Decreased efficiency of transcription (D) All of these

Last Answer : Answer : C

The region of the Lac operon which must be free from structural gene transcription to occur is (A) The operator locus (B) The promoter site (C) The ‘a’ gene (D) The ‘i’ gene

Description : The region of the Lac operon which must be free from structural gene transcription to occur is (A) The operator locus (B) The promoter site (C) The ‘a’ gene (D) The ‘i’ gene

Last Answer : Answer : A

Which one of the following binds to specific nucleotide sequences that are upstream and most distant from the start site? (A) RNA polymerase (B) Repressor (C) Inducer (D) Restriction

Description : Which one of the following binds to specific nucleotide sequences that are upstream and most distant from the start site? (A) RNA polymerase (B) Repressor (C) Inducer (D) Restriction

Last Answer : Answer : A

Which one of the following binds to specific nucleotide sequences? (A) RNA polymerase (B) Repressor (C) Inducer (D) Restriction

Description : Which one of the following binds to specific nucleotide sequences? (A) RNA polymerase (B) Repressor (C) Inducer (D) Restriction

Last Answer : Answer : A

During translation initiation in prokaryotes, a GTP molecule is needed in (a) formation of formyl-met-tRNA (b) binding of 30S subunit of ribosome with mRNA (c) association of 30S mRNA with formyl-met- tRNA (d) association of 50S subunit of ribosome with initiation complex.

Description : During translation initiation in prokaryotes, a GTP molecule is needed in (a) formation of formyl-met-tRNA (b) binding of 30S subunit of ribosome with mRNA (c) association of 30S mRNA with formyl-met- tRNA (d) association of 50S subunit of ribosome with initiation complex.

Last Answer : (c) association of 30S mRNA with formyl-met- tRNA

.The first phase of translation is (a) binding of mRNA to ribosome (b) recognition of DNA molecule (c) aminoacylation of tRNA (d) recognition of an anti-codon

Description : .The first phase of translation is (a) binding of mRNA to ribosome (b) recognition of DNA molecule (c) aminoacylation of tRNA (d) recognition of an anti-codon

Last Answer : (d) recognition of an anti-codon.

.During translation initiation in prokaryotes, a GTP molecule is needed in (a) formation of formyl-met-tRNA (b) binding of 30S subunit of ribosome with mRNA (c) association of 30S mRNA with formyl-met- tRNA (d) association of 50S subunit of ribosome with initiation complex.

Description : .During translation initiation in prokaryotes, a GTP molecule is needed in (a) formation of formyl-met-tRNA (b) binding of 30S subunit of ribosome with mRNA (c) association of 30S mRNA with formyl-met- tRNA (d) association of 50S subunit of ribosome with initiation complex.

Last Answer : (c) association of 30S mRNA with formyl-met- tRNA

The first phase of translation is (a) binding of mRNA to ribosome (b) recognition of DNA molecule (c) aminoacylation of tRNA (d) recognition of an anti-codon.

Description : The first phase of translation is (a) binding of mRNA to ribosome (b) recognition of DNA molecule (c) aminoacylation of tRNA (d) recognition of an anti-codon.

Last Answer : c) aminoacylation of tRNA

The structural genes of lac operon transcribe mRNA which is a) polycistronic b) replicative c) monokaryotic d) monocistronic

Description : The structural genes of lac operon transcribe mRNA which is a) polycistronic b) replicative c) monokaryotic d) monocistronic

Last Answer : a) polycistronic

Silencer elements (A) Are trans-acting factors (B) Are present between promoters and the structural genes (C) Decrease the expression of some structural genes (D) Encode specific repressor proteins

Description : Silencer elements (A) Are trans-acting factors (B) Are present between promoters and the structural genes (C) Decrease the expression of some structural genes (D) Encode specific repressor proteins

Last Answer : Answer : C

The binding of prokaryotic DNA dependent RNA polymerase to promoter sits of genes is inhibited by the antibiotic: (A) Streptomycin (B) Rifamcin (C) Aueromycin (D) Puromycin

Description : The binding of prokaryotic DNA dependent RNA polymerase to promoter sits of genes is inhibited by the antibiotic: (A) Streptomycin (B) Rifamcin (C) Aueromycin (D) Puromycin

Last Answer : Answer : B

The binding of prokaryotic DNA dependent RNA polymerase to promoter sites of genes is inhibited by the antibiotic: (A) Puromycin (B) Rifamycin (C) Terramycin (D) Streptomycin

Description : The binding of prokaryotic DNA dependent RNA polymerase to promoter sites of genes is inhibited by the antibiotic: (A) Puromycin (B) Rifamycin (C) Terramycin (D) Streptomycin

Last Answer : Answer : B

RNA polymerase holoenzyme binds to lac operon at the following site: (A) i gene (B) z gene (C) Operator locus (D) Promoter region

Description : RNA polymerase holoenzyme binds to lac operon at the following site: (A) i gene (B) z gene (C) Operator locus (D) Promoter region

Last Answer : Answer : D

Initiation of protein synthesis begins with binding of (A) 40S ribosomal unit on mRNA (B) 60S ribosomal unit (C) Charging of tRNA with specific amino acid (D) Attachment of aminoacyl tRNA on mRNA

Description : Initiation of protein synthesis begins with binding of (A) 40S ribosomal unit on mRNA (B) 60S ribosomal unit (C) Charging of tRNA with specific amino acid (D) Attachment of aminoacyl tRNA on mRNA

Last Answer : Answer : A

Regulator gene controls chemical synthesis (Operon concept) by (a) Inhibiting transcription of mRNA (b) Inhibiting enzymes (c) Inhibiting passage of mRNA (d) Inhibiting substrate enzyme reaction

Description : Regulator gene controls chemical synthesis (Operon concept) by (a) Inhibiting transcription of mRNA (b) Inhibiting enzymes (c) Inhibiting passage of mRNA (d) Inhibiting substrate enzyme reaction

Last Answer : Ans. ((a))

Trancription of z, y and a genes of lac operon is prevented by (A) Lactose (B) Allo-lactose (C) Repressor (D) cAMP

Description : Trancription of z, y and a genes of lac operon is prevented by (A) Lactose (B) Allo-lactose (C) Repressor (D) cAMP

Last Answer : Answer : C

In mammals, synthesis of mRNA is catalysed by (A) RNA polymerase I (B) RNA polymerase II (C) RNA polymerase III(D) RNA polymerase IV

Description : In mammals, synthesis of mRNA is catalysed by (A) RNA polymerase I (B) RNA polymerase II (C) RNA polymerase III(D) RNA polymerase IV

Last Answer : Answer : B

Synthesis of RNA and a DNA template is known as (A) Replication (B) Translation (C) Transcription (D) Mutation

Description : Synthesis of RNA and a DNA template is known as (A) Replication (B) Translation (C) Transcription (D) Mutation

Last Answer : Answer : C

The role of molecular chaperones is to A-facilitate binding of ribosomes to mRNA B-degrade newly synthesized polypeptides that contain inaccurate sequences C-.facilitate binding of RNA polymerase to DNA D-aid a newly synthesized polypeptide in folding to its proper shape

Description : The role of molecular chaperones is to A-facilitate binding of ribosomes to mRNA B-degrade newly synthesized polypeptides that contain inaccurate sequences C-.facilitate binding of RNA polymerase to DNA D-aid a newly synthesized polypeptide in folding to its proper shape

Last Answer : -aid a newly synthesized polypeptide in folding to its proper shape

The role of molecular chaperones is to A-facilitate binding of ribosomes to mRNA B-degrade newly synthesized polypeptides that contain inaccurate sequences C-.facilitate binding of RNA polymerase to DNA D-aid a newly synthesized polypeptide in folding to its proper shape

Description : The role of molecular chaperones is to A-facilitate binding of ribosomes to mRNA B-degrade newly synthesized polypeptides that contain inaccurate sequences C-.facilitate binding of RNA polymerase to DNA D-aid a newly synthesized polypeptide in folding to its proper shape

Last Answer : aid a newly synthesized polypeptide in folding to its proper shape

The region of DNA known as TATA BOX is the site for binding of (A) DNA polymerase (B) DNA topoisomerase (C) DNA dependent RNA polymerase (D) Polynucleotide phosphorylase

Description : The region of DNA known as TATA BOX is the site for binding of (A) DNA polymerase (B) DNA topoisomerase (C) DNA dependent RNA polymerase (D) Polynucleotide phosphorylase

Last Answer : Answer : C

The smallest unit of DNA capable of coding for the synthesis of a polypeptide is (A) Operon (B) Repressor gene (C) Cistron (D) Replicon

Description : The smallest unit of DNA capable of coding for the synthesis of a polypeptide is (A) Operon (B) Repressor gene (C) Cistron (D) Replicon

Last Answer : Answer : C

Which of the following statement(s) is/are true concerning translation of the mRNA message to protein synthesis? a. An adaptor molecule, tRNA, recognizes specific nucleic acid bases and unites them with specific amino acids b. Covalent attachment of tRNA to amino acids is energy dependent c. The formation of a peptide bond between the growing peptide chain and the free amino acid occurs in the free cytoplasm d. Complete protein synthesis takes hours

Description : Which of the following statement(s) is/are true concerning translation of the mRNA message to protein synthesis? a. An adaptor molecule, tRNA, recognizes specific nucleic acid bases and unites them ... and the free amino acid occurs in the free cytoplasm d. Complete protein synthesis takes hours

Last Answer : Answer: a, b The synthesis of protein involves conversion from a four-letter nucleotide language to one of 20 chemically distinct amino acids. This process is referred to as ... translation and be moving down the mRNA molecules simultaneously, thus increasing the rate of protein synthesis

What happens at the ribosome in the production of a protein? a. mRNA brings the codon b. tRNA brings the anticodon c. the amino acids are linked by polypeptide bonds d. translation e. all the above

Description : What happens at the ribosome in the production of a protein? a. mRNA brings the codon b. tRNA brings the anticodon c. the amino acids are linked by polypeptide bonds d. translation e. all the above

Last Answer : c. the amino acids are linked by polypeptide bonds

Positive control of induction is best described as a control system in which an operon functions (A) Unless it is switched off by a derepressed repressor protein (B) Only after a repressor protein is inactivated by an inducer (C) Only after an inducer protein, which can be inactivated by a corepressor, switches it on (D) Only after an inducer protein, which is activated by an inducer, switch it on

Description : Positive control of induction is best described as a control system in which an operon functions (A) Unless it is switched off by a derepressed repressor protein (B) Only after a repressor protein is ... on (D) Only after an inducer protein, which is activated by an inducer, switch it on

Last Answer : Answer : D

Match the following genes of the Lac operon with their respective products. (A) i gene (i) b-galactosidase (B) z gene (ii) Permease (C) a gene (iii)Repressor (D) y gene (iv) Transacetylase Select the correct option. (A) (B) (C) (D) (a) (iii) (iv) (i) (ii) (b) (i) (iii) (ii) (iv) (c) (iii) (i) (ii) (iv) (d) (iii) (i) (iv) (ii)

Description : Match the following genes of the Lac operon with their respective products. (A) i gene (i) b-galactosidase (B) z gene (ii) Permease (C) a gene (iii)Repressor (D) y gene (iv) Transacetylase Select the correct option. (A) (B) (C) ( ... ) (iii) (ii) (iv) (c) (iii) (i) (ii) (iv) (d) (iii) (i) (iv) (ii)

Last Answer : (a) (iii) (iv) (i) (ii)

Match the following genes of the Lac operon with their respective products. (A) i gene (i) b-galactosidase (B) z gene (ii) Permease (C) a gene (iii)Repressor (D) y gene (iv) Transacetylase Select the correct option. (A) (B) (C) (D) (a) (iii) (iv) (i) (ii) (b) (i) (iii) (ii) (iv) (c) (iii) (i) (ii) (iv) (d) (iii) (i) (iv) (ii)

Description : Match the following genes of the Lac operon with their respective products. (A) i gene (i) b-galactosidase (B) z gene (ii) Permease (C) a gene (iii)Repressor (D) y gene (iv) Transacetylase Select the correct option. (A) (B) (C) ( ... ) (iii) (ii) (iv) (c) (iii) (i) (ii) (iv) (d) (iii) (i) (iv) (ii)

Last Answer : d) (iii) (i) (iv) (ii)