All of the following statements about eukaryotic promoters are true except (A) They may be located upstream or down stream from the structural gene (B) They have two consensus sequences (C) One consensus sequence binds RNA polymerase (D) Mutations in promoter region can decrease the efficiency of transcription of the structural gene

All of the following statements about eukaryotic promoters are true except (A) They may be located upstream or down stream from the structural gene (B) They have two consensus sequences (C) One consensus sequence binds RNA polymerase (D) Mutations in promoter region can decrease the efficiency of transcription of the structural gene
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All of the following statements about bacterial promoters are true except (A) They are smaller than eukaryotic promoters (B) They have two consensus sequences upstream from the transcription star site (C) TATA box is the site for attachment of RNA polymerase (D) TATA box has a high melting temperature

Description : All of the following statements about bacterial promoters are true except (A) They are smaller than eukaryotic promoters (B) They have two consensus sequences upstream from the transcription star site (C) ... is the site for attachment of RNA polymerase (D) TATA box has a high melting temperature

Last Answer : Answer : D

Mutations in promoter regions of genes can cause (A) Premature termination of translation (B) Change in reading frame of downstream structural gene (C) Decreased efficiency of transcription (D) All of these

Description : Mutations in promoter regions of genes can cause (A) Premature termination of translation (B) Change in reading frame of downstream structural gene (C) Decreased efficiency of transcription (D) All of these

Last Answer : Answer : C

RNA polymerase holoenzyme binds to lac operon at the following site: (A) i gene (B) z gene (C) Operator locus (D) Promoter region

Description : RNA polymerase holoenzyme binds to lac operon at the following site: (A) i gene (B) z gene (C) Operator locus (D) Promoter region

Last Answer : Answer : D

Which one of the following binds to specific nucleotide sequences that are upstream and most distant from the start site? (A) RNA polymerase (B) Repressor (C) Inducer (D) Restriction

Description : Which one of the following binds to specific nucleotide sequences that are upstream and most distant from the start site? (A) RNA polymerase (B) Repressor (C) Inducer (D) Restriction

Last Answer : Answer : A

During transcription, the DNA site at which RNA polymerase binds is called (a) promoter (b) regulator (c) receptor (d) enhancer.

Description : During transcription, the DNA site at which RNA polymerase binds is called (a) promoter (b) regulator (c) receptor (d) enhancer.

Last Answer : d) enhancer

During transcription, the DNA site at which RNA polymerase binds is called (a) promoter (b) regulator (c) receptor (d) enhancer.

Description : During transcription, the DNA site at which RNA polymerase binds is called (a) promoter (b) regulator (c) receptor (d) enhancer.

Last Answer : (a) promoter

Eukaryotic promoters contain (A) TATA box 25bp upstream of transcription start site (B) CAAT box 70-80 bp upstream of transcription start site (C) Both (A) and (B) (D) None of these

Description : Eukaryotic promoters contain (A) TATA box 25bp upstream of transcription start site (B) CAAT box 70-80 bp upstream of transcription start site (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

CAAT box is present in (A) Prokaryotic promoters 10 bp upstream of transcription start site (B) Prokaryotic promoters 35 bp upstream of transcription start site (C) Eukaryotic promoters 25 bp upstream of transcription start site (D) Eukaryotic promoters 70–80 bp upstream of transcription start site

Description : CAAT box is present in (A) Prokaryotic promoters 10 bp upstream of transcription start site (B) Prokaryotic promoters 35 bp upstream of transcription start site (C) Eukaryotic promoters 25 bp upstream of transcription start site (D) Eukaryotic promoters 70–80 bp upstream of transcription start site

Last Answer : Answer : D

The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Description : The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Last Answer : .is located immediately upstream of the start codon

The rivosome binding site A- forms a sltem- loop structure in the RNA B- is located upstream of the promoter sequence C- is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Description : The rivosome binding site A- forms a sltem- loop structure in the RNA B- is located upstream of the promoter sequence C- is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Last Answer : is located immediately upstream of the start codon

The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Description : The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Last Answer : .is located immediately upstream of the start codon

Enhancer elements have all the following features except (A) They increase gene expression through a promoter (B) Each enhancer activates a specific promoter (C) They may be located far away from the promoter (D) They may be upstream or downstream from the promoter

Description : Enhancer elements have all the following features except (A) They increase gene expression through a promoter (B) Each enhancer activates a specific promoter (C) They may be located far away from the promoter (D) They may be upstream or downstream from the promoter

Last Answer : Answer : B

The region of the Lac operon which must be free from structural gene transcription to occur is (A) The operator locus (B) The promoter site (C) The ‘a’ gene (D) The ‘i’ gene

Description : The region of the Lac operon which must be free from structural gene transcription to occur is (A) The operator locus (B) The promoter site (C) The ‘a’ gene (D) The ‘i’ gene

Last Answer : Answer : A

To commence structural gene transcription the region which should be free on lac operation is (A) Promoter site (B) Operator locus (C) Y gene (D) A gene

Description : To commence structural gene transcription the region which should be free on lac operation is (A) Promoter site (B) Operator locus (C) Y gene (D) A gene

Last Answer : Answer : B

During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called? (a) AAAT box (b) TATA box (c) GGTT box (d) CAAT box

Description : During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called? (a) AAAT box (b) TATA box (c) GGTT box (d) CAAT box

Last Answer : (c) GGTT box

During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called? (a) AAAT box (b) TATA box (c) GGTT box (d) CAAT box

Description : During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called? (a) AAAT box (b) TATA box (c) GGTT box (d) CAAT box

Last Answer : (b) TATA box

Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) Attaching to promoter region and facilitating the binding of RNA polymerase holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus

Description : Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) ... holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus

Last Answer : Answer : D

Binding of RNA polymerase holoenzyme to the promoter region of lac operon is facilitated by (A) Catabolite gene activator protein (CAP) (B) cAMP (C) CAP-cAMP complex (D) None of these

Description : Binding of RNA polymerase holoenzyme to the promoter region of lac operon is facilitated by (A) Catabolite gene activator protein (CAP) (B) cAMP (C) CAP-cAMP complex (D) None of these

Last Answer : Answer : C

The function of a repressor protein in an operon system is to prevent synthesis by binding to (A) The ribosome (B) A specific region of the operon preventing transcription of structural genes (C) The RNA polymerase (D) A specific region of the mRNA preventing translation to protein

Description : The function of a repressor protein in an operon system is to prevent synthesis by binding to (A) The ribosome (B) A specific region of the operon preventing transcription of structural genes (C) The RNA polymerase (D) A specific region of the mRNA preventing translation to protein

Last Answer : Answer : B

Which one of the following binds to specific nucleotide sequences? (A) RNA polymerase (B) Repressor (C) Inducer (D) Restriction

Description : Which one of the following binds to specific nucleotide sequences? (A) RNA polymerase (B) Repressor (C) Inducer (D) Restriction

Last Answer : Answer : A

Which one of the following is wrongly matched? (a) Transcription - Writing information from DNA to tRNA. (b) Translation - Using information in mRNA to make protein. (c) Repressor protein - Binds to operator to stop enzyme synthesis. (d) Operon - Structural genes, operator and promoter.

Description : Which one of the following is wrongly matched? (a) Transcription - Writing information from DNA to tRNA. (b) Translation - Using information in mRNA to make protein. (c) Repressor protein - Binds to operator to stop enzyme synthesis. (d) Operon - Structural genes, operator and promoter.

Last Answer : (c) Repressor protein - Binds to operator to stop enzyme synthesis.

Which one of the following is wrongly matched? (a) Transcription - Writing information from DNA to tRNA. (b) Translation - Using information in mRNA to make protein. (c) Repressor protein - Binds to operator to stop enzyme synthesis. (d) Operon - Structural genes, operator and promoter.

Description : Which one of the following is wrongly matched? (a) Transcription - Writing information from DNA to tRNA. (b) Translation - Using information in mRNA to make protein. (c) Repressor protein - Binds to operator to stop enzyme synthesis. (d) Operon - Structural genes, operator and promoter.

Last Answer : (d) Operon - Structural genes, operator and promoter

A consensus sequence on DNA, called TATA box, is the site for attachment of (A) RNA-dependent DNA polymerase (B) DNA-dependent RNA polymerase (C) DNA-dependent DNA polymerase (D) DNA topoisomerase II

Description : A consensus sequence on DNA, called TATA box, is the site for attachment of (A) RNA-dependent DNA polymerase (B) DNA-dependent RNA polymerase (C) DNA-dependent DNA polymerase (D) DNA topoisomerase II

Last Answer : Answer : B

Transcription of structural genes of lac operon is prevented by binding of the repressor tetramer to (A) i gene (B) Operator locus (C) Promoter (D) z gene

Description : Transcription of structural genes of lac operon is prevented by binding of the repressor tetramer to (A) i gene (B) Operator locus (C) Promoter (D) z gene

Last Answer : Answer : B

In E. coli, during lactose metabolism repressor binds to (a) regulator gene (b) operator gene (c) structural gene (d) promoter gen

Description : In E. coli, during lactose metabolism repressor binds to (a) regulator gene (b) operator gene (c) structural gene (d) promoter gen

Last Answer : (b) operator gene

The ‘rho’ (ρ) factor is involved (A) To increase the rate of RNA synthesis (B) In binding catabolite repressor to the promoter region (C) In proper termination of transcription (D) To allow proper initiation of transcriptide

Description : The ‘rho’ (ρ) factor is involved (A) To increase the rate of RNA synthesis (B) In binding catabolite repressor to the promoter region (C) In proper termination of transcription (D) To allow proper initiation of transcriptide

Last Answer : Answer : C

Which one of the following is not a part of a transcription unit in DNA? (a) The inducer (b) A terminator (c) A promoter (d) The structural gene

Description : Which one of the following is not a part of a transcription unit in DNA? (a) The inducer (b) A terminator (c) A promoter (d) The structural gene

Last Answer : (c) A promoter

Which one of the following is not a part of a transcription unit in DNA? (a) The inducer (b) A terminator (c) A promoter (d) The structural gene

Description : Which one of the following is not a part of a transcription unit in DNA? (a) The inducer (b) A terminator (c) A promoter (d) The structural gene

Last Answer : (a) The inducer

Which one of the following is not a part of a transcription unit in DNA ? (1) The structural gene (2) The inducer (3) A terminator (4) A promoter

Description : Which one of the following is not a part of a transcription unit in DNA ? (1) The structural gene (2) The inducer (3) A terminator (4) A promoter

Last Answer : (2) The inducer

In the process of transcription in bacterial cells (A) Initiation requires rho protein (B) RNA polymerase incorporates methylated bases in correct sequence (C) Both the sigma unit and core enzymes of RNA polymerase are required for accurate promotor site binding (D) Primase is necessary for initiation

Description : In the process of transcription in bacterial cells (A) Initiation requires rho protein (B) RNA polymerase incorporates methylated bases in correct sequence (C) Both the sigma unit and core ... RNA polymerase are required for accurate promotor site binding (D) Primase is necessary for initiation

Last Answer : Answer : C

An important step in protein synthesis is transcription. Which of the following statement(s) is/are true concerning this process? a. The first step in gene transcription involves separating the double helix of DNA by an enzyme known as DNA polymerase b. The initial product of DNA transcription is called heterogeneous nuclear RNA which codes directly for proteins c. After processing is complete, the mRNA is exported from the nucleus to the cytoplasm d. Only one protein can be produced from an initial mRNA strand

Description : An important step in protein synthesis is transcription. Which of the following statement(s) is/are true concerning this process? a. The first step in gene transcription involves separating the double helix ... nucleus to the cytoplasm d. Only one protein can be produced from an initial mRNA strand

Last Answer : Answer: c Transcription of a gene begins at an initiation site associated with a specific DNA sequence, termed a promoter region. After binding to DNA, the RNA polymerase opens up a short ... different proteins from the same gene. mRNA is exported from the nucleus only after processing is complete

Suppressor tRNAs can neutralize the effects of mutations in (A) Structural genes (B) Promoter regions (C) Enhancer elements(D) All of these

Description : Suppressor tRNAs can neutralize the effects of mutations in (A) Structural genes (B) Promoter regions (C) Enhancer elements(D) All of these

Last Answer : Answer : A

Suppressor mutations occur in (A) Structural genes (B) Promoter regions (C) Silencer elements (D) Anticodons of tRNA

Description : Suppressor mutations occur in (A) Structural genes (B) Promoter regions (C) Silencer elements (D) Anticodons of tRNA

Last Answer : Answer : D

Nondisjunction of a chromosome results in which of the following diagnoses? a) Down Syndrome When a pair of chromosomes fails to separate completely and creates a sperm or oocyte that contains two copies of a particular chromosome (nondisjunction) Down syndrome results from three number 21 chromosomes. b) Huntingon Disease Huntington disease is one example of a germ-line mutation. c) Duchenne Muscular Dystrophy Duchenne muscular dystrophy, an inherited form of muscular dystrophy, is an example of a genetic caused by structural gene mutations. d) Marphan Syndrome Marphan Syndrome is a genetic condition that may occur in a single family member as a result of spontaneous mutation.

Description : Nondisjunction of a chromosome results in which of the following diagnoses? a) Down Syndrome When a pair of chromosomes fails to separate completely and creates a sperm or oocyte that contains two ... genetic condition that may occur in a single family member as a result of spontaneous mutation.

Last Answer : a) Down Syndrome When a pair of chromosomes fails to separate completely and creates a sperm or oocyte that contains two copies of a particular chromosome (nondisjunction) Down syndrome results from three number 21 chromosomes.

Ras proto-oncogene is converted into oncogene by (A) A point mutation (B) Chromosomal translocation (C) Insertion of a viral promoter upstream of the gene (D) Gene amplification

Description : Ras proto-oncogene is converted into oncogene by (A) A point mutation (B) Chromosomal translocation (C) Insertion of a viral promoter upstream of the gene (D) Gene amplification

Last Answer : Answer : A

The coding sequences in lac operon include (A) i gene (B) i gene, operator locus and promoter (C) z, y and a genes (D) i, z, y and a genes

Description : The coding sequences in lac operon include (A) i gene (B) i gene, operator locus and promoter (C) z, y and a genes (D) i, z, y and a genes

Last Answer : Answer : D

All the following statements about retino blastoma are true except (A) At least two mutations are required for its development (B) One mutation can be inherited from a parent (C) Children who have inherited one mutation develop retinoblastoma at a younger age (D) RB 1 gene promotes the development of retinoblastoma

Description : All the following statements about retino blastoma are true except (A) At least two mutations are required for its development (B) One mutation can be inherited from a parent (C) Children ... mutation develop retinoblastoma at a younger age (D) RB 1 gene promotes the development of retinoblastoma

Last Answer : Answer : D

How would the transcription of the eukaryotic gene be affected if a replication error changed the nucleotide sequence of the termination signal for that gene?

Description : How would the transcription of the eukaryotic gene be affected if a replication error changed the nucleotide sequence of the termination signal for that gene?

Last Answer : Extra long proteins are likely to fold improperly and notfunction correctly. The overall health of the individual would bedestroyed.

Cistron is a) The coding sequence of DNA b) The functional unit of DNA molecule that codes for a particular gene product c) Intervening non coding sequence of DNA d) The sequences which are removed during RNA splicing.

Description : Cistron is a) The coding sequence of DNA b) The functional unit of DNA molecule that codes for a particular gene product c) Intervening non coding sequence of DNA d) The sequences which are removed during RNA splicing.

Last Answer : b) The functional unit of DNA molecule that codes for a particular gene product c) Intervening non coding sequence of DNA

The binding of prokaryotic DNA dependent RNA polymerase to promoter sits of genes is inhibited by the antibiotic: (A) Streptomycin (B) Rifamcin (C) Aueromycin (D) Puromycin

Description : The binding of prokaryotic DNA dependent RNA polymerase to promoter sits of genes is inhibited by the antibiotic: (A) Streptomycin (B) Rifamcin (C) Aueromycin (D) Puromycin

Last Answer : Answer : B

The binding of prokaryotic DNA dependent RNA polymerase to promoter sites of genes is inhibited by the antibiotic: (A) Puromycin (B) Rifamycin (C) Terramycin (D) Streptomycin

Description : The binding of prokaryotic DNA dependent RNA polymerase to promoter sites of genes is inhibited by the antibiotic: (A) Puromycin (B) Rifamycin (C) Terramycin (D) Streptomycin

Last Answer : Answer : B

Silencer elements (A) Are trans-acting factors (B) Are present between promoters and the structural genes (C) Decrease the expression of some structural genes (D) Encode specific repressor proteins

Description : Silencer elements (A) Are trans-acting factors (B) Are present between promoters and the structural genes (C) Decrease the expression of some structural genes (D) Encode specific repressor proteins

Last Answer : Answer : C

All of the following statements about RNA-dependent DNA polymerase are true except: (A) It synthesizes DNA using RNA as a template (B) It is also known as reverse transcriptase (C) It synthesizes DNA in 5’→3’ direction (D) It is present in all the viruses

Description : All of the following statements about RNA-dependent DNA polymerase are true except: (A) It synthesizes DNA using RNA as a template (B) It is also known as reverse transcriptase (C) It synthesizes DNA in 5’→3’ direction (D) It is present in all the viruses

Last Answer : Answer : D

Select the two correct statements out of the four (i – iv) statements given below about lac operon. (i) Glucose or galactose may bind with the repressor and inactivate it. (ii) In the absence of lactose, the repressor binds with the operator region. (iii)The z-gene codes for permease. (iv) This was elucidated by Francois Jacob and Jacques Monod. The correct statements are (a) (ii) and (iii) (b) (i) and (iii) (c) (ii) and (iv) (d) (i) and (ii)

Description : Select the two correct statements out of the four (i - iv) statements given below about lac operon. (i) Glucose or galactose may bind with the repressor and inactivate it. (ii) In the absence of lactose, the repressor binds with the ... (iii) (b) (i) and (iii) (c) (ii) and (iv) (d) (i) and (ii)

Last Answer : (c) (ii) and (iv)

Repressor binds to DNA sequence and regulate the transcription. This sequence is called (A) Attenuator (B) Terminator (C) Anti terminator (D) Operator

Description : Repressor binds to DNA sequence and regulate the transcription. This sequence is called (A) Attenuator (B) Terminator (C) Anti terminator (D) Operator

Last Answer : Answer : D

What is antisense technology? (a) When a piece of RNA that is complementary in sequence is used to stop expression of a specific gene (b) RNA polymerase producing DNA (c) A cell displaying a foreign antigen used for synthesis of antigens (d) Production of somaclonal variants in tissue cultures

Description : What is antisense technology? (a) When a piece of RNA that is complementary in sequence is used to stop expression of a specific gene (b) RNA polymerase producing DNA (c) A cell displaying a foreign antigen used for synthesis of antigens (d) Production of somaclonal variants in tissue cultures

Last Answer : (a) When a piece of RNA that is complementary in sequence is used to stop expression of a specific gene

Which of the following statements is not true for retroviruses? (a) DNA is not present at any stage in the life cycle of retroviruses. (b) Retroviruses carry gene(c) The genetic material in mature retroviruses is RNA. (d) Retroviruses are causative agents for certain kinds of cancer in man. for RNA-dependent DNA polymerase.

Description : Which of the following statements is not true for retroviruses? (a) DNA is not present at any stage in the life cycle of retroviruses. (b) Retroviruses carry gene for RNA-dependent DNA ... mature retroviruses is RNA. (d) Retroviruses are causative agents for certain kinds of cancer in man.

Last Answer : (a) DNA is not present at any stage in the life cycle of retroviruses

Which of the following is transcribed during repression? (A) Structural gene (B) Promoter gene (C) Regulator gene (D) Operator gene

Description : Which of the following is transcribed during repression? (A) Structural gene (B) Promoter gene (C) Regulator gene (D) Operator gene

Last Answer : Answer : C

Lac operon is a cluster of (A) Three structural genes (B) Three structural genes and their promoter (C) A regulatory gene, an operator and a promoter (D) A regulatory gene, an operator, a promoter and three structural genes

Description : Lac operon is a cluster of (A) Three structural genes (B) Three structural genes and their promoter (C) A regulatory gene, an operator and a promoter (D) A regulatory gene, an operator, a promoter and three structural genes

Last Answer : Answer : D

The gene which is transcribed during repression is (A) Structural (B) Regulator (C) Promoter (D) Operator

Description : The gene which is transcribed during repression is (A) Structural (B) Regulator (C) Promoter (D) Operator

Last Answer : Answer : B