The binding of prokaryotic DNA dependent RNA polymerase to promoter sites of genes is inhibited by the antibiotic: (A) Puromycin (B) Rifamycin (C) Terramycin (D) Streptomycin

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Answer :  B

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Description : The binding of prokaryotic DNA dependent RNA polymerase to promoter sits of genes is inhibited by the antibiotic: (A) Streptomycin (B) Rifamcin (C) Aueromycin (D) Puromycin

Last Answer : Answer : B

Description : The antibiotic which inhibits DNA dependent RNA polymerase is (A) Mitomycin C (B) Actinomycin d (C) Streptomycin (D) Puromycin

Last Answer : Answer : B

Description : The antibiotic which cleaves DNA is (A) Actinomycin d (B) Streptomycin (C) Puromycin (D) Mitomycin C

Last Answer : Answer : D

Description : Negative regulation of protein synthesis is accomplished by A- allosteric inhibition B- the binding of RNA polymerase to the promoter C- the binding of a repressor to the DNA D- the binding of a repressor to the RNA polymerase

Last Answer : the binding of a repressor to the DNA

Description : The region of DNA known as TATA BOX is the site for binding of (A) DNA polymerase (B) DNA topoisomerase (C) DNA dependent RNA polymerase (D) Polynucleotide phosphorylase

Last Answer : Answer : C

Description : The antibiotic which has a structure similar to the amino acyl end of tRNA tyrosine is (A) Actinomycin d (B) Streptomycin (C) Puromycin (D) Mitomycin c

Last Answer : Answer : C

Description : Lactose or its analogues act as positive regulators of lac operon by (A) Attaching to i gene and preventing its expression (B) Increasing the synthesis of catabolite gene activator protein (C) ... holoenzyme (D) Binding to repressor subunits so that the repressor cannot attach to the operator locus

Last Answer : Answer : D

Description : Binding of RNA polymerase holoenzyme to the promoter region of lac operon is facilitated by (A) Catabolite gene activator protein (CAP) (B) cAMP (C) CAP-cAMP complex (D) None of these

Last Answer : Answer : C

Description : Which was the first antibiotic - (1) Terramycin (2) Neomycin (3) Penicilin (4) Streptomycin

Last Answer : (3) Penicilin Explanation: Penicillin is a group of antibiotics derived from Penicillium fungi. They include penicillin G, procaine penicillin, benzathine penicillin, and penicillin V. Penicillin ... Penicillins are still widely used today, though many types of bacteria are now resistant.

Description : Which was the first antibiotic ? (1) Terramycin (2) Neomycin (3) Penicilin (4) Streptomycin

Last Answer : Penicilin

Description : The mechanism of antibacterial action of tetracycline involves (a) Binding to a component of the 50S ribosomal subunit (b) Inhibition of translocase activity (c) Blockade of binding of ... (d) Selective inhibition of ribosomal peptidyl transferases (e) Inhibition of DNA-dependent RNA polymerase

Last Answer : Ans: C

Description : Rifampin kills tubercle bacilli by: A. Binding to mycobacterial DNA dependent RNA polymerase B. Inhibiting mycobacterial DNA synthesis C. Inhibiting synthesis of mycolic acids in mycobacteria D. Damaging mycobacterial mitochondria

Last Answer : A. Binding to mycobacterial DNA dependent RNA polymerase

Description : The function of a repressor protein in an operon system is to prevent synthesis by binding to (A) The ribosome (B) A specific region of the operon preventing transcription of structural genes (C) The RNA polymerase (D) A specific region of the mRNA preventing translation to protein

Last Answer : Answer : B

Description : Binding of formylmehtionyl tRNA to 30 S ribosomal subunit of prokaryotes is inhibited by (A) Streptomycin (B) Chloramphenicol (C) Erythromycin (D) Mitomycin

Last Answer : Answer : A

Description : During transcription, the DNA site at which RNA polymerase binds is called (a) promoter (b) regulator (c) receptor (d) enhancer.

Last Answer : d) enhancer

Description : During transcription, the DNA site at which RNA polymerase binds is called (a) promoter (b) regulator (c) receptor (d) enhancer.

Last Answer : (a) promoter

Description : Another name for reverse transcriptase is (A) DNA dependent DNA polymerase (B) DNA dependent RNA polymerase (C) RNA dependent DNA polymerase (D) RNA dependent RNA polymerase

Last Answer : Answer : C

Description : α-Amanitin inhibits (A) DNA polymerase II of prokaryotes (B) DNA polymerase α of eukaryotes (C) RNA polymerase II of eukaryotes (D) RNA-dependent DNA polymerase

Last Answer : Answer : C

Description : A consensus sequence on DNA, called TATA box, is the site for attachment of (A) RNA-dependent DNA polymerase (B) DNA-dependent RNA polymerase (C) DNA-dependent DNA polymerase (D) DNA topoisomerase II

Last Answer : Answer : B

Description : The termination site for transcription is recognized by (A) α−Subunit of DNA-dependent RNA polymerase (B) β−Subunit of DNA-dependent RNA polymerase (C) Sigma factor (D) Rho factor

Last Answer : Answer : D

Description : The initiation site for transcription is recognized by (A) α−Subunit of DNA-dependent RNA polymerase (B) β−Subunit of DNA-dependent RNA polymerase (C) Sigma factor (D) Rho factor

Last Answer : Answer : C

Description : DNA-dependent RNA polymerase requires the following for its catalytic activity: (A) Mg++ (B) Mn++ (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

Description : DNA-dependent RNA polymerase is a (A) Monomer (B) Dimer (C) Trimer (D) Tetramer

Last Answer : Answer : D

Description : All of the following statements about RNA-dependent DNA polymerase are true except: (A) It synthesizes DNA using RNA as a template (B) It is also known as reverse transcriptase (C) It synthesizes DNA in 5’→3’ direction (D) It is present in all the viruses

Last Answer : Answer : D

Description : The coupling of oxidation and phosphorylation in intact mitochondria: (A) Puromycin (B) Oligomycin (C) Streptomycin (D) Gentamycin

Last Answer : Answer : B

Description : Transcription of structural genes of lac operon is prevented by binding of the repressor tetramer to (A) i gene (B) Operator locus (C) Promoter (D) z gene

Last Answer : Answer : B

Description : RNA polymerase holoenzyme binds to lac operon at the following site: (A) i gene (B) z gene (C) Operator locus (D) Promoter region

Last Answer : Answer : D

Description : All of the following statements about eukaryotic promoters are true except (A) They may be located upstream or down stream from the structural gene (B) They have two consensus sequences ( ... (D) Mutations in promoter region can decrease the efficiency of transcription of the structural gene

Last Answer : Answer : A

Description : The ‘rho’ (ρ) factor is involved (A) To increase the rate of RNA synthesis (B) In binding catabolite repressor to the promoter region (C) In proper termination of transcription (D) To allow proper initiation of transcriptide

Last Answer : Answer : C

Description : The role of molecular chaperones is to A-facilitate binding of ribosomes to mRNA B-degrade newly synthesized polypeptides that contain inaccurate sequences C-.facilitate binding of RNA polymerase to DNA D-aid a newly synthesized polypeptide in folding to its proper shape

Last Answer : -aid a newly synthesized polypeptide in folding to its proper shape

Description : The role of molecular chaperones is to A-facilitate binding of ribosomes to mRNA B-degrade newly synthesized polypeptides that contain inaccurate sequences C-.facilitate binding of RNA polymerase to DNA D-aid a newly synthesized polypeptide in folding to its proper shape

Last Answer : aid a newly synthesized polypeptide in folding to its proper shape

Description : Which of the following is effective against tuberculosis? (1) Penicillin (2) Chloromycetin (3) Terramycin (4) Streptomycin

Last Answer : (4) Streptomycin Explanation: Streptomycin is an antibiotic drug, the first of a class of drugs called amino glycosides to be discovered, and it was the first antibiotic remedy for ... antibiotic. Streptomycin cannot be given orally, but must be administered by regular intramuscular injections.

Description : Which of the following is effective against tuberculosis ? (1) Penicillin (2) Chloromycetin (3) Terramycin (4) Streptomycin

Last Answer : Streptomycin

Description : DNA-dependent RNA polymerase catalyzes transcription on one strand of the DNA which is called the

Last Answer : DNA-dependent RNA polymerase catalyzes transcription on one strand of the DNA which is called the ... Antistrand C. Template strand D. Coding strand

Description : DNA-dependent RNA polymerase catalyses transcription on one strand of the DNA which is called the (a) template strand (b) coding strand (c) alpha strand (d) antistrand

Last Answer : (a) template strand

Description : DNA-dependent RNA polymerase catalyses transcription on one strand of the DNA which is called the (a) template strand (b) coding strand (c) alpha strand (d) antistrand.

Last Answer : (a) template strand

Description : Which of the following statements is not true for retroviruses? (a) DNA is not present at any stage in the life cycle of retroviruses. (b) Retroviruses carry gene for RNA-dependent DNA ... mature retroviruses is RNA. (d) Retroviruses are causative agents for certain kinds of cancer in man.

Last Answer : (a) DNA is not present at any stage in the life cycle of retroviruses

Description : In the process of transcription in bacterial cells (A) Initiation requires rho protein (B) RNA polymerase incorporates methylated bases in correct sequence (C) Both the sigma unit and core ... RNA polymerase are required for accurate promotor site binding (D) Primase is necessary for initiation

Last Answer : Answer : C

Description : The given antibiotic is an example of ansamycins : (A) Roxythromycin (B) Adriamycin (C) Aureomycin (D) Rifamycin

Last Answer : (D) Rifamycin

Description : The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Last Answer : .is located immediately upstream of the start codon

Description : The rivosome binding site A- forms a sltem- loop structure in the RNA B- is located upstream of the promoter sequence C- is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Last Answer : is located immediately upstream of the start codon

Description : The ribosome binding site A- forms a stem-loop structure in the RNA B- is located upstream of the promoter sequence C- .is located immediately upstream of the start codon D- is more likely to be associated with an operon than with a gene encoding a single protein

Last Answer : .is located immediately upstream of the start codon

Description : Which binding is inhibited by pactamycin? A- Aminoacyl-tRNA to the A-site of 30S subunit B- Initiator-tRNA to 30S/40S initiation complexes C- Peptidyl t-RNA to the 50S subunit D- Formation of peptide bond in P site

Last Answer : Initiator-tRNA to 30S/40S initiation complexes

Description : After termination of the synthesis of RNA molecule, the core enzymes separate from the DNA template. The core enzymes then recognize a promoter at which the synthesis of a new RNA molecule commences, with the assistance of (A) Rho (ρ) factor (B) δ factor (C) β factor (D) σ factor

Last Answer : Answer : D

Description : Template-directed DNA synthesis occurs in all the following except (A) The replication fork (B) Polymerase chain reaction (C) Growth of RNA tumor viruses (D) Expression of oncogenes

Last Answer : Answer : C

Description : Template-directed DNA synthesis occurs in all the following except (A) The replication fork (B) Polymerase chain reaction (C) Growth of RNA tumor viruses (D) Expression of oneogenes

Last Answer : Answer : C

Description : RNA directed DNA polymerase is (A) Replicase (B) Transcriptase (C) Reversetranscriptase (D) Polymerase–III

Last Answer : Answer : C

Description : DNA directed RNA polymerase is (A) Replicase (B) Transcriptase (C) Reverse transcriptase (D) Polymerase III

Last Answer : Answer : B

Description : Ribonucleotides of RNA primer are replaced by deoxyribonucleotides by the enzyme: (A) DNA polymerase I (B) DNA polymerase II (C) DNA polymerase III holoenzyme (D) All of these

Last Answer : Answer : A

Description : Deoxyribonucleotides are added to RNA primer by (A) DNA polymerase I (B) DNA polymerase II (C) DNA polymerase III holoenzyme (D) All of these

Last Answer : Answer : C