Description : Xeroderma pigmentosum results from a defect in (A) uvr ABC excinuclease (B) DNA polymerase I (C) DNA ligase (D) All of these
Last Answer : Answer : A
Description : Damage to DNA caused by ultraviolet radiation can be repaired by (A) uvr ABC excinuclease (B) DNA polymerase I (C) DNA ligase (D) All of these
Last Answer : Answer : D
Description : Zinc deficiency occurs commonly in (A) Acrodermatitis enteropathica (B) Wilson’s disease (C) Xeroderma pigmentosum (D) Menke’s disease
Description : All of the following statements about Tangier disease are true except (A) It is a disorder of HDL metabolism (B) Its inheritance is autosomal recessive (C) Apoproteins A-I and A-II are not synthesised (D) Plasma HDL is increased
Description : All are true about lesch-nyhan syndrome except (A) Produces self-mutilation (B) Genetic deficiency of the enzyme (C) Elevated levels of uric acid in blood (D) Inheritance is autosomal recessive
Last Answer : Answer : B
Description : Which of the following diseases is a chronic, progressive, hereditary disease of the nervous system that results in progressive involuntary dance-like movement and dementia? a) Huntington's ... the central nervous system characterized by spongiform degeneration of the gray matter of the brain.
Last Answer : a) Huntington’s disease Because it is transmitted as an autosomal dominant genetic disorder, each child of a parent with HD has a 50% risk of inheriting the illness.
Description : Which type of Mendelian inherited condition results in both genders being affected equally in a vertical pattern? a) Automosomal dominant inheritance An individual who has an autosomal dominant ... that combine during early embryonic development leading to incomplete closure of the neural tube.
Last Answer : a) Automosomal dominant inheritance An individual who has an autosomal dominant inherited condition carries a gene mutation for that condition on one chromosome of a pair.
Description : A man and a woman, who do not show any apparent signs of a certain inherited disease, have seven children (2 daughters and 5 sons). Three of the sons suffer from the given disease but none ... ? (a) Sex-linked dominant (b) Sex-linked recessive (c) Sex-limited recessive (d) Autosomal dominant
Last Answer : (b) Sex-linked recessive
Description : Inheritance of primary gout is (A) Autosomal recessive (B) Autosomal dominant (C) X-linked recessive (D) X-linked dominant
Last Answer : Answer : C
Description : Which of the following is a characteristic feature of familial hypercholesterolaemia? 1) Autosomal dominant inheritance 2) elevated chylomicrons 3) hypertriglyceridaemia 4) increased expression of LDL receptors 5) Palmar xanthomas
Last Answer : Answers-1 Familial hypercholesterolaemia is an autosomal dominant condition manifest by increased LDL concentrations (not chylomicrons) due to constitutional abnormalities and reduced numbers of ... are characteristic and the condition is associated with a premature cardiovascular mortality.
Description : What is an autosomal dominant pattern of inheritance?
Last Answer : Need answer
Description : What type of inheritance pattern (are the A and B alleles to each other (Autosomal dominant-Regular dominant-recessive relationship, X linked, co-dominant, incomplete dominant)?
Last Answer : Incomplete dominance
Description : All the following statements about restriction fragment length polymorphism are true except (A) It results from mutations in restriction sites (B) Mutations in restriction sites can occur in coding or non- ... It is inherited in Mendelian fashion (D) It can be used to diagnose any genetic disease
Description : What are the autosomal dominant genetic disorders?
Last Answer : What is the answer ?
Description : All the following statements about cystic fibrosis are correct except (A) It is inherited as an autosomal recessive disease (B) It affects a number of exocrine glands (C) It causes increased sweating (D) Sweat chlorides are above 60 mEq/L in this disease
Description : Which of the following is true of Gilbert's syndrome? 1) inheritance is autosomal recessive 2) serum conjugated bilirubin levels are elevated 3) serum bilirubin levels are decreased by fasting 4) serum bilirubin levels are decreased by liver enzyme inducers 5) there is bilirubinuria
Last Answer : Answers-4 Gilbert's syndrome is inherited in autosomal dominant fashion and affects 2-5% of the population. UDP glucuronyl transferase levels are reduced leading to an unconjugated hyperbilirubinaemia. ... the bilirubin is reabsorbed in the proximal tubule some bilirubin is detectable in the urine.
Description : How is analyzing the inheritance patterns of sickle cell disease through pedigrees allowed scientists to determine that the disease is autosomal recessive?
Last Answer : Feel Free to Answer
Description : Study the pedigree chart given below. What does it show? (a) Inheritance of a condition like phenylketonuria as an autosomal recessive trait. (b) The pedigree chart is wrong as this is ... disease like haemophilia. (d) Inheritance of a sex-linked inborn error of metabolism like phenylketonuria
Last Answer : (a) Inheritance of a condition like phenylketonuria as an autosomal recessive trait.
Description : Which of the following is a Dominant Autosomal Disorder? (1) Albinism (2) Cystic Fibrosis (3) Phenyl Ketorunia (4) Alzheimer's Disease
Last Answer : (4) Alzheimer's Disease Explanation: In an autosomal dominant disorder, the mutated gene is a dominant gene located on one of the nonsex chromosomes (autosomes). The early-onset form of Alzheimer ... the disorder. In most cases, an affected person inherits the altered gene from one affected parent.
Description : .A diseased man marries a normal woman. They get three daughters and five sons. All the daughters were diseased and sons were normal. The gene of this disease is (a) sex linked dominant (b) sex linked recessive (c) sex limited character (d) autosomal dominant.
Last Answer : (a) sex linked dominant
Description : Which of the following is a Dominant Autosomal Disorder? (1) Albinism (2) Cystic Fibrosis (3) Phenyl Ketorunia (4) Alzheimer’s Disease
Last Answer : Alzheimer’s Disease
Description : Which one is the incorrect statement with regard to the importance of pedigree analysis? (a) It confirms that DNA is the carrier of genetic information. (b) It helps to understand whether the trait in ... linked to one of the autosome. (d) It helps to trace the inheritance of a specific trait.
Last Answer : (a) It confirms that DNA is the carrier of genetic information.
Description : Which of the following is a characteristic feature of acute intermittent porphyria? 1) autosomal recessive inheritance 2) excessive faecal protoporphyrin excretion 3) excessive urinary porphobilinigoen between acute attacks 4) hypernatraemia during attacks 5) photosensitivity
Last Answer : Answers-3 Features of acute intermittent porphyria include urinary porphobilinogen excretion raised between attacks, hyponatraemia during an acute attack and autosomal dominant inheritance.
Description : Which of the following is associated with Hyperuricaemia? 1) is usually due to an excess purine consumption 2) occurs in association with acute lymphoblastic leukaemia 3) in primary gout is inherited in ... with low dose aspirin therapy 5) can be treated with uricosuric drugs even in renal failure
Last Answer : Answers-2 Hyperuricaemia may be due to increased purine intake, urate production or reduced urate clearance, and is most commonly due to the latter. Therefore it can occur in association with enhanced ... . Many of the uricosuric drugs may be detrimental in renal failure and may not be effective.
Description : All the following statements about recognition of a codon on mRNA by an anticodon on tRNA are correct except (A) The recognition of the third base of the codon is not very precise (B) ... degeneracy of the genetic code (D) Wobble results in incorporation of incorrect amino acids in the protein
Description : Situations in which one allele for a gene is not completely dominant over another allele for that gene are called a. multiple alleles. b. incomplete dominance. c. polygenic inheritance. d. multiple genes.
Last Answer : b. incomplete dominance.
Description : All the following statements about primary gout are true except (A) Its inheritance is X-linked recessive (B) It can be due to increased activity of PRPP synthetase (C) It can be ... activity of hypoxanthine guanine phosphoribosyl transferase (D) De novo synthesis of purines is increased in it
Description : All the following statements about Wilson’s disease are correct except (A) It is a genetic disease (B) The defect involves copper-dependent P-type ATPase (C) Copper is deposited in liver, basal ganglia and around cornea (D) Plasma copper level is increased in it
Description : All the following statements about albinism are correct except (A) Tyrosine hydroxylase (tyrosinase) is absent or deficient in melanocytes (B) Skin is hypopigmented (C) It results in mental retardation (D) Eyes are hypopigmented
Description : In autosomal recessive inheritance: a. the rarer the trait the higher the possibility of marriages within the same family b. most recessive gene defects cause problem through failure to produce functional protein c. both males and females are affected equally severely d. all above
Last Answer : all above
Description : Autosomal dominant?
Last Answer : DefinitionAutosomal dominant is one of several ways that a trait or disorder can be passed down through families.If a disease is autosomal dominant, it means you only need to get the abnormal ... means an abnormal gene from one parent is capable of causing disease, even though the matchin
Description : With regard to blood groups and blood products: a. the ABO system is inherited in an autosomal dominant pattern b. group O and Rhesus positive is the universal donors' blood. ... dextrose, phosphate and citrate d. stored blood becomes progressively more acidotic and hyperkalaemic with time
Last Answer : stored blood becomes progressively more acidotic and hyperkalaemic with time
Description : . Sickle-cell anaemia is (a) caused by substitution of valine by glutamic acid in the beta globin chain of haemoglobin (b) caused by a change in a single base pair of DNA (c) characterized by elongated sickle like RBCs with a nucleus (d) an autosomal linked dominant trait.
Last Answer : (b) caused by a change in a single base pair of DNA
Description : n the following human pedigree, the filled symbols represent the affected individuals. Identify the type of given pedigree. (i) (ii) (iii) (iv) (a) Autosomal recessive (b) X-linked dominant (c) Autosomal dominant (d) X-linked recessive
Last Answer : (a) Autosomal recessive
Description : Select the correct match. (a) Haemophilia – Y linked (b) Phenylketonuria – Autosomal dominant trait (c) Sickle cell anaemia – Autosomal recessive trait,chromosome -11 (d) Thalassemia – X linked
Last Answer : (c) Sickle cell anaemia – Autosomal recessive trait,chromosome -11
Description : Which of the following statements regarding neutrophils are true? a. The neutrophil undergoes final maturation after release into the circulation b. Patients with chronic granulomatous disease have a defective ... proteins d. The normal human neutrophil circulates in the blood for 7-10 days
Last Answer : Answer: b, c The neutrophil is a migratory phagocytic cell that defends the host against bacteria and eliminates necrotic tissue. The neutrophil matures in the bone marrow and is ... phagocytose bacteria, they are unable to kill the intracellular microbes and chronic, unresolved infections result
Description : Pick out the correct statements. (1) Haemophilia is a sex-linked recessive disease. (2) Down's syndrome is due to aneuploidy. (3) Phenylketonuria is an autosomal recessive gene disorder. (4) Sickle cell anaemia is an X- ... are correct. (c) (1) and (4) are correct. (d) (2) and (4) are correct.
Last Answer : (b) (1), (2) and (3) are correct.
Description : Depletion of which gas in the atmosphere can lead to an increased incidence of skin cancers:
Last Answer : Depletion of which gas in the atmosphere can lead to an increased incidence of skin cancers: A. Methane B. Nitrous oxide C. Ozone D. ammonia.
Last Answer : Depletion of which gas in the atmosphere can lead to an increased incidence of skin cancers: A. Nitrous oxide B. Ozone C. Ammonia D. Methane
Description : A genetically diseased father (male) marries with a normal female and gives birth to 3 carrier girls and 5 normal sons. It may be which type of genetic disease? (a) Sex-influenced disease (b) Blood group inheritance disease (c) Sex-linked disease (d) Sex-recessive disease
Last Answer : (c) Sex-linked disease
Description : In human beings, multiple genes are involved in the inheritance of (a) sickle-cell anaemia (b) skin colour (c) colour blindness (d) phenylketonuria.
Last Answer : ) skin colour
Description : A child is mentally retarded with defective teeth and loose wrinkled skin. a) From which disease is the child suffering? b) What is the disease due to?
Last Answer : The child is suffering from cretinism. The disease is caused in children due to improper functioning of thyroid gland.
Description : Mention autosomal genetic disorders with their symptoms. -Biology
Last Answer : answer:
Description : Which of the following genetic disorders in man are caused by a dominant gene? 1. Edwards Syndrome 2. Huntington's disease 3. Marfan Syndrome 4. Thalassemia Select the correct answer using codes given below: (a) 1 and 3 (b) 1 and 4 (c) 2 and 3 (d) 2 and 4
Last Answer : Ans:(c)
Description : All the following statements about endemic goiter are true except (A) It occurs in areas where soil and water have low iodine content (B) It leads to enlargement of thyroid gland (C) It results ultimately in hyperthyroidism (D) It can be prevented by consumption of iodised salt
Description : All of the following statements about generalized gangliosidosis are true except (A) It results from deficiency of GM1-βGangliosidase (B) Breakdown of GM1 ganglioside is impaired (C) GM2 ganglioside accumulates in liver and elsewhere (D) It leads to mental retardation
Description : All of the following statements about multiple sclerosis are true except (A) There is loss of phospholipids from white matter (B) There is loss of sphingolipids from white matter (C) There is loss of esterified cholesterol from white matter (D) White matter resembles gray matter in composition
Description : All of the following statements about bronzed diabetes are true except (A) It is caused by excessive intake of copper (B) Skin becomes pigmented (C) There is damage to β cells of Islets of Langerhans (D) Liver is damaged
Description : Three medications referred to as the ABC drugs' are currently the main pharmacological therapy for multiple sclerosis. Which of the following statements reflects information to be included in patient ... on an empty stomach. Glatiramer acetate is administed by intramuscular injection once a week.
Last Answer : a) Flu-like symptoms can be controlled with nonsteroidal antiinflammatory drugs (NSAIDs) and usually resolve after a few months of therapy. Seventy-five percent of patients taking one of the ... symptoms that can be controlled with NSAIDS and usually resolve after a few months of therapy.