DefinitionInfectious endocarditis is an infection of the lining of the heart chambers and heart valves that is caused by bacteria, fungi, or other infectious substances.See also:Culture-negative endocarditisEndocarditisAlternative NamesEndocarditis - infectiousCauses, incidence, and risk factorsEndocarditis is usually a result of a blood infection. Bacteria or other infectious substance can enter the bloodstream during certain medical procedures, including dental procedures, and travel to the heart, where it can settle on damaged heart valves. The bacteria can grow and may form infected clots that break off and travel to the brain, lungs, kidneys, or spleen.Most people who develop infectious endocarditis have underlying heart disease or valve problems.However, an organism commonly found in