Why in inflammatory and infectious conditions may clinical signs related to the lymphatic system occur?

Why in inflammatory and infectious conditions may clinical signs related to the lymphatic system occur?
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The lymph nodes, or lymph glands, have lymphoid tissue that produces lymphocytes (a type of leukocyte). In inflammatory and infectious conditions the enlargement of lymph nodes of the lymphatic circuits that drain the affected region due to the reactive proliferation of leukocytes is common. This enlargement is known as lymphadenomegaly and sometimes it is accompanied by pain. The search for enlarged or painful lymph nodes is part of the medical examination since these findings may suggest inflammation, infection or other diseases. The Circulatory System - Image Diversity: lymphadenopathy
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