DefinitionThe CSF-VDRL test is used to diagnose neurosyphilis. This test looks for antibodies called reagins, which are sometimes produced by the body in reaction to the syphilis-causing bacteria.See also: VDRLAlternative NamesVenereal disease research laboratory slide test - CSFHow the test is performedThe test is performed on a CSF sample obtained by lumbar puncture (spinal tap).How to prepare for the testBefore the procedure, you will be asked to review the risks and sign a consent form.How the test will feelUsually, discomfort associated with the lumbar puncture is mild to moderate. The entire procedure usually takes about 30 minutes but may take longer. The actual fluid collection only takes a few minutes.Why the test is performedThe CSF-VDRL test is used to diagnose syphilis in the b