DefinitionCirrhosis is scarring of the liver and poor liver function as a result of chronic liver disease.Alternative NamesLiver cirrhosisCauses, incidence, and risk factorsCirrhosis is caused by chronic liver disease. Common causes of chronic liver disease in the United States include:Hepatitis CinfectionLong-term alcohol abuse (see alcoholic liver disease)Other causes of cirrhosis include:Autoimmune inflammation of the liverDisorders of the drainage system of the liver (the biliary system), such as primary biliary cirrhosisand primary sclerosing cholangitisHepatitis BMedicationsMetabolic disorders of iron and copper (hemochromatosis and Wilson's disease)Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH)SymptomsSymptoms may develop gradually, or there may be