Description : Binding of acetylcholine to its receptors increases the permeability of cell membrane to (A) Ca++ (B) Na+ (C) K+ (D) Na+ and K+
Last Answer : Answer : D
Description : In myasthenia gravis: a. the vertical muscles of the eye are more commonly involved than the horizontal muscles b. the pupil reaction to light is sluggish c. absent antibody to acetylcholine receptors exclude the diagnosis d. Cogan's twitch refers to involuntary twitching of the orbicularis
Last Answer : the vertical muscles of the eye are more commonly involved than the horizontal muscles
Description : The following are true about acetylcholine: a. it has a strong affinity for nicotinic receptors b. is derived from acetyl CoA and choline c. is synthesized by a reaction involving choline acetyltransferase d. all above
Last Answer : all above
Description : The following are true: a. heroin causes miosis by increasing the release of acetylcholine. b. botulinum toxin causes mydriasis by inhibiting the release of acetylcholine c. ... mydriasis by stimulating the alpha receptors d. amphetamine causes mydriasis by inhibiting noradrenaline reuptake
Last Answer : phenylephrine causes mydriasis by stimulating the alpha receptors
Description : The following are true about acetylcholine receptors: a. receptors at all autonomic ganglia are nicotinic b. receptors at the skeletal neuromuscular junction are muscarinic c. ... atropine d. acetylcholine receptors in the neuromuscular junction can be selectively blocked by tubocurarine
Last Answer : acetylcholine receptors in the neuromuscular junction can be selectively blocked by tubocurarine
Description : With regard to the autonomic nervous system: a. the dorsal root ganglia is made up mainly of the cell bodies of the sympathetic nerves b. the preganglionic sympathetic fibres ... the ganglia of both sympathetic and parasympathetic nervous system d. botulin toxin blocks acetylcholine receptors
Last Answer : the dorsal root ganglia is made up mainly of the cell bodies of the sympathetic nerves
Description : Myasthenia Gravis is characterized by Options: 1) Decrease in acetylcholine reserve in motor nerve terminal 2) Decrease in dopamine reserve in motor nerve terminal 3) Decrease in receptors for acetylcholine 4) Decrease in dopamine receptors
Last Answer : Correct Answer: 3) Decrease in receptors for acetylcholine
Description : Select the prokinetic-antiemetic drug which at relatively higher doses blocks both dopamine D2 as well as 5-HT3 receptors and enhances acetylcholine release from myenteric neurones: A. Cisapride B. Prochlorperazine C. Metoclopramide D. Domperidon
Last Answer : C. Metoclopramide
Description : Activation of the following type of receptors present on myenteric neurones by metoclopramide is primarily responsible for enhanced acetylcholine release improving gastric motility: A. Muscarinic M1 B. Serotonergic 5-HT3 C. Serotonergic 5-HT4 D. Dopaminergic D2
Last Answer : C. Serotonergic 5-HT4
Description : Histamine H2 blockers attenuate the gastric secretory response to acetylcholine and pentagastrin as well because: A. H2 blockers block gastric mucosal cholinergic and gastrin receptors as well B. H2 ... acetylcholine and gastrin all act through the phospholipase C-IP3:DAG pathway in gastric mucosa
Last Answer : C. Acetylcholine and gastrin act partly by releasing histamine in gastric mucosa
Description : The mechanism by which neostigmine improves contraction of myasthenic muscle involves: A. Repetitive binding of the acetylcholine molecules to the same receptors at the muscle endplate B. Diffusion of ... Activation of motor end-plate receptors by neostigmine molecules themselves D. All of the above
Last Answer : D. All of the above
Description : With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the ... is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.
Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.
Description : In which category of muscle fibers, contraction can be regulated by acetylcholine neurotransmitter ?
Last Answer : In which category of muscle fibers, contraction can be regulated by acetylcholine neurotransmitter ? A. ... . Smooth muscle fibers D. all of these
Description : Tyrosine kinase activity is present in (A) Acetylcholine receptor (B) PDGF receptor (C) ADH receptor (D) All of these
Last Answer : Answer : B
Description : Zinc is involved in storage and release of (A) Histamine (B) Acetylcholine (C) Epinephrine (D) Insulin
Description : Which one of the following can be blocked by atropine? (a) Decreased blood pressure caused by hexamethonium (b) Increased blood pressure caused by nicotine (c) Increased skeleton muscle ... by neostigmine (d) Tachycardia caused by exercise (e) Tachycardia caused by infusion of acetylcholine
Last Answer : Ans: E
Description : Which of the following agents is a prodrug that is much less toxic in mammals than in insects ? (a) Acetylcholine (b) Bethanechol (c) Physostigmine (d) Pilocarpine (e) Neostigmine
Last Answer : Ans: C
Description : A direct-acting cholinomimetic that is lipid-soluble and often used in the treatment of glaucoma is (a) Acetylcholine (b) Bethanechol (c) Physostigmine (d) Pilocarpine (e) Neostigmine
Last Answer : Ans: D
Description : The neurotransmitter agent that is normally released in the sinoatrial node of the heart in response to a blood pressure increase is (a) Acetylcholine (b) Dopamine (c) Epinephrine (d) Glutamate (e) Norepinephrine
Last Answer : Ans: A
Description : A mast cell (or mastocyte) is a resident cells of several types of tissues and contains many granules rich in_______. a) Acetylcholine b) Nicotine c) Epinephrine d) Histamine e) Histadine
Description : The muscle fatigue occurs due to the release of (a) acetylcholine (b) lactic acid (c) adrenaline (d) none of these
Last Answer : Ans:(b)
Description : Benzimidazoles work against parasites by A A. Binding with protein tubulin B. Mimicking acetylcholine C. Both D. None of above
Last Answer : Binding with protein tubuli
Description : Nicotine acts as a stimulant, because it mimics the effect of (a) testosterone (b) dopamine (c) thyroxine (d) acetylcholine.
Last Answer : (d) acetylcholine.
Description : The following are true about pupil reaction to light: a. secretion of acetylcholine is responsible for pupil dilatation b. constriction of the pupil is mediated by nerve fibres travelling in ... fibres travelling in the long ciliary nerve d. the sympathetic nerve innervates the dilator muscles
Last Answer : the sympathetic nerve innervates the dilator muscles
Description : The release of acetylcholine is blocked by: a. hemicholinum b. venom of black widow spider c. cocaine d. botulinum toxins
Last Answer : botulinum toxins
Description : The following are neurotransmitters in the autonomic ganglia: a. GABA b. noradrenaline c. acetylcholine d. 5 HT
Last Answer : acetylcholine
Description : The following are neurotransmitters at the autonomic post-ganglionic nerve endings: a. GABA b. noradrenaline c. acetylcholine d. 5 HT
Description : The following are true about the neurotransmitters: a. acetylcholine is inactivated mainly by presynaptic reuptake b. tyrosine is essential for the formation of dopamine c. noradrenaline is inactivated mainly by hydrolysis d. adrenaline is formed from methylation of the noradrenaline
Last Answer : adrenaline is formed from methylation of the noradrenaline
Description : The following are true about acetylcholine: a. it is synthesized from acetyl-coenzyme A and choline b. its formation is catalysed by acetylcholinesterase c. at the synaptic cleft, ... inactivated by hydrolysis d. reuptake by the presynaptic neurones play an important in inactivating acetylcholine
Last Answer : at the synaptic cleft, it is inactivated by hydrolysis
Description : Acetylcholine is a neurotransmitter at: a. sweat glands b. the adrenal medulla c. parasympathetic ganglia d. all above
Description : The secretion of insulin is stimulated by: a. adrenaline b. somatostatin c. fatty acids d. acetylcholine
Last Answer : fatty acids
Description : The following enzymes on the left are responsible for the synthesis of the neurotransmitters on the right: a. monoamine oxidase: noradrenaline b. cholinesterase: acetylcholine c. catechol-o-methyl transferase: dopamine d. dopa decarboxylase: adrenaline
Last Answer : dopa decarboxylase: adrenaline
Description : Parkinson’s disease (characterized by tremors and progressive rigidity of limbs) is caused by degeneration of brain neurons that are involved in movement control and make use of neurotransmitter (a) acetylcholine (b) norepinephrine (c) dopamine (d) GABA.
Last Answer : c) dopamine
Description : Which one of the following does not act as a neurotransmitter? (a) Cortisone (b) Acetylcholine (c) Epinephrine (d) Norepinephrine
Last Answer : (a) Cortisone
Description : Alzheimer’s disease in humans is associated with the deficiency of (a) glutamic acid (b) acetylcholine (c) gamma aminobutyric acid (GABA) (d) dopamine.
Last Answer : b) acetylcholine
Description : Nicotinic action of acetylcholine is blocked by the drug (A) Atropine (B) Carvedilol (C) Neostigmine ( D ) d-Tubocurarine
Last Answer : ( D ) d-Tubocurarine
Description : The mechanisms involved in the causation of dangerous cardiac arrhythmias due to overdose of tricyclic antidepressants include the following except: A. Intraventricular conduction block B. Potentiation of noradrenaline C. Antagonism of acetylcholine D. Increased vagal tone
Last Answer : D. Increased vagal tone
Description : Dantrolene sodium reduces skeletal muscle tone by: A. Reducing acetylcholine release from motor nerve endings B. Suppressing spinal polysynaptic reflexes C. Inhibiting the generation of muscle action potential D. Reducing Ca2+ release from sarcoplasmic reticulum in the muscle fibre
Last Answer : D. Reducing Ca2+ release from sarcoplasmic reticulum in the muscle fibre
Description : The organophosphates produce irreversible inhibition of cholinesterase because: A. They bind to an allosteric site of the enzyme resulting in unfavourable conformation of esteratic site to bind ... degradation of enzyme molecules D. They are neither metabolized nor excreted from the body
Last Answer : B. Regeneration time of the phosphorylated enzyme is longer than the turnover time of the enzyme molecules
Description : Acetylcholine has no therapeutic application because: A. None of its actions are beneficial in any condition B. Its effects are transient C. It produces wide spread actions affecting many organs D. Both ‘B’ and ‘C’ are correct
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : Which of the following secretions is not stimulated by acetylcholine: A. Tear B. Bile C. Pancreatic juice D. Sweat
Last Answer : B. Bile
Description : Pseudocholinesterase differs from true cholinesterase in that: A. It does not hydrolyse acetylcholine B. It hydrolyses acetylcholine at a slower rate C. It is more susceptible to inhibition by physostigmine D. It is the only form of circulating cholinesterase
Last Answer : B. It hydrolyses acetylcholine at a slower rate
Description : Tetrodotoxin blocks nerve impulse/junctional transmission by: A. Anticholinergic action B. Depleting acetylcholine C. Blocking Na+ channels D. Blocking Ca2+ channels
Last Answer : C. Blocking Na+ channels