Nicotinic action of acetylcholine is blocked by the drug (A) Atropine (B) Carvedilol (C) Neostigmine ( D ) d-Tubocurarine

Nicotinic action of acetylcholine is blocked by the drug
(A) Atropine (B) Carvedilol
(C) Neostigmine ( D ) d-Tubocurarine
by

1 Answer

Answer :

( D ) d-Tubocurarine
by

Related questions

The following are true about acetylcholine receptors: a. receptors at all autonomic ganglia are nicotinic b. receptors at the skeletal neuromuscular junction are muscarinic c. acetylcholine receptors in the autonomic ganglia can be selectively blocked by atropine d. acetylcholine receptors in the neuromuscular junction can be selectively blocked by tubocurarine

Description : The following are true about acetylcholine receptors: a. receptors at all autonomic ganglia are nicotinic b. receptors at the skeletal neuromuscular junction are muscarinic c. ... atropine d. acetylcholine receptors in the neuromuscular junction can be selectively blocked by tubocurarine

Last Answer : acetylcholine receptors in the neuromuscular junction can be selectively blocked by tubocurarine

Which one of the following can be blocked by atropine? (a) Decreased blood pressure caused by hexamethonium (b) Increased blood pressure caused by nicotine (c) Increased skeleton muscle strength caused by neostigmine (d) Tachycardia caused by exercise (e) Tachycardia caused by infusion of acetylcholine

Description : Which one of the following can be blocked by atropine? (a) Decreased blood pressure caused by hexamethonium (b) Increased blood pressure caused by nicotine (c) Increased skeleton muscle ... by neostigmine (d) Tachycardia caused by exercise (e) Tachycardia caused by infusion of acetylcholine

Last Answer : Ans: E

The vitamin essential in tissue culture medium is (A) Pyridoxine (B) Thiamine (C) Nicotinic acid (D) Inositol

Description : The vitamin essential in tissue culture medium is (A) Pyridoxine (B) Thiamine (C) Nicotinic acid (D) Inositol

Last Answer : (B) Thiamine

The neuromuscular blocker that does not need reversal of action by neostigmine at the end of the operation is: A. d-Tubocurarine B. Doxacurium C. Pipecuronium D. Mivacurium

Description : The neuromuscular blocker that does not need reversal of action by neostigmine at the end of the operation is: A. d-Tubocurarine B. Doxacurium C. Pipecuronium D. Mivacurium

Last Answer : D. Mivacurium

Pancuronium differs from tubocurarine in that: A. It is a depolarizing blocker B. Its action is not reversed by neostigmine C. It can cause rise in BP on rapid I.V. injection D. It causes marked histamine release

Description : Pancuronium differs from tubocurarine in that: A. It is a depolarizing blocker B. Its action is not reversed by neostigmine C. It can cause rise in BP on rapid I.V. injection D. It causes marked histamine release

Last Answer : C. It can cause rise in BP on rapid I.V. injection

Myasthenia gravis is diagnosed with improved neuromuscular function by using (A) Donepezil (B) Edrophonium (C) Atropine (D) Pancuronium

Description : Myasthenia gravis is diagnosed with improved neuromuscular function by using (A) Donepezil (B) Edrophonium (C) Atropine (D) Pancuronium

Last Answer : (B) Edrophonium

Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Description : Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Last Answer : C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate

Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Description : Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Last Answer : C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate

A 70-year-old man has severe urinary hesitancy associated with benign prostatic hyperplasia. He has tried alpha blockers with little relief. His physician recommends a drug that blocks 5a - reductase in the prostate and writes a prescription for (a) Atropine (b) Clonidine (c) Hydralazine (d) Neostigmine (e) Propranolol

Description : A 70-year-old man has severe urinary hesitancy associated with benign prostatic hyperplasia. He has tried alpha blockers with little relief. His physician recommends a drug that blocks 5a - reductase in ... prescription for (a) Atropine (b) Clonidine (c) Hydralazine (d) Neostigmine (e) Propranolol

Last Answer : Ans: B

Neostigmine reverses the following actions of d-tubocurarine except: A. Motor weakness B. Ganglionic blockade C. Histamine release D. Respiratory paralysis

Description : Neostigmine reverses the following actions of d-tubocurarine except: A. Motor weakness B. Ganglionic blockade C. Histamine release D. Respiratory paralysis

Last Answer : C. Histamine release

It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 hr and Vd of 5 L. The dose required in a sustained release product will be (A) 600 mg (B) 300 mg (C) 30 mg (D) 60 mg

Description : It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 hr and Vd of 5 L. The dose required in a sustained release product will be (A) 600 mg (B) 300 mg (C) 30 mg (D) 60 mg

Last Answer : (B) 300 mg

The Volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be (A)10 L (B) 100 L (C) 1.0 L (D) 0.10 L

Description : The Volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be (A)10 L (B) 100 L (C) 1.0 L (D) 0.10 L

Last Answer : (A)10 L

A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram hr/mL, respectively. The absolute availability of the drug through oral administration is : (A) 125% (B) 250 % (C) 12.5% (D) 1.25%

Description : A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram hr/mL, respectively. The absolute availability of the drug through oral administration is : (A) 125% (B) 250 % (C) 12.5% (D) 1.25%

Last Answer : (C) 12.5%

The temperature condition for storage of drug products under cold temperature is given as : (A) temperature between 8°C and 25°C (B) temperature below 20 C (C) temperature at 0°C (D) temperature between 2c C and S: C

Description : The temperature condition for storage of drug products under cold temperature is given as : (A) temperature between 8°C and 25°C (B) temperature below 20 C (C) temperature at 0°C (D) temperature between 2c C and S: C

Last Answer : (D) temperature between 2c C and S: C

Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products? (A) Sodium chloride (B) Mannitol (C) Starch (D) HPMC

Description : Which one of the following is the commonly used bulking agent in the formulation of freeze dried low dose drug products? (A) Sodium chloride (B) Mannitol (C) Starch (D) HPMC

Last Answer : (B) Mannitol

Measurement of inulin renal clearance is a measure for (A) Effective renal blood flow (B) Renal drug excretion rate (C) Active renal secretion (D) Glomerular filtration rate

Description : Measurement of inulin renal clearance is a measure for (A) Effective renal blood flow (B) Renal drug excretion rate (C) Active renal secretion (D) Glomerular filtration rate

Last Answer : (D) Glomerular filtration rate

Which one of the following is a flocculating agent for a negatively charged drug? (A) Aluminium chloride (B) Bentonite (C) Tragacanth (D) Sodium biphosphate

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Last Answer : (A) Aluminium chloride

The characteristic of non-linear pharmacokinetics include : (A) Area under the curve is proportional to the dose (B) Elimination half-life remains constant, (C) Area under the curve is not proportional to the dose (D) Amount of drug excreted through remains constant

Description : The characteristic of non-linear pharmacokinetics include : (A) Area under the curve is proportional to the dose (B) Elimination half-life remains constant, (C) Area under the curve is not proportional to the dose (D) Amount of drug excreted through remains constant

Last Answer : (C) Area under the curve is not proportional to the dose

Identify the drug which is NOT used in the treatment of malaria caused by Plasmodium falciparum : (A.) Artemisinin (B) Primaquine (C) Quinine (D) Mefloquine

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Which of the following agents is a prodrug that is much less toxic in mammals than in insects ? (a) Acetylcholine (b) Bethanechol (c) Physostigmine (d) Pilocarpine (e) Neostigmine

Description : Which of the following agents is a prodrug that is much less toxic in mammals than in insects ? (a) Acetylcholine (b) Bethanechol (c) Physostigmine (d) Pilocarpine (e) Neostigmine

Last Answer : Ans: C

A direct-acting cholinomimetic that is lipid-soluble and often used in the treatment of glaucoma is (a) Acetylcholine (b) Bethanechol (c) Physostigmine (d) Pilocarpine (e) Neostigmine

Description : A direct-acting cholinomimetic that is lipid-soluble and often used in the treatment of glaucoma is (a) Acetylcholine (b) Bethanechol (c) Physostigmine (d) Pilocarpine (e) Neostigmine

Last Answer : Ans: D

The mechanism by which neostigmine improves contraction of myasthenic muscle involves: A. Repetitive binding of the acetylcholine molecules to the same receptors at the muscle endplate B. Diffusion of acetylcholine released from motor nerve endings to a wider area activating neighbouring receptors C. Activation of motor end-plate receptors by neostigmine molecules themselves D. All of the above

Description : The mechanism by which neostigmine improves contraction of myasthenic muscle involves: A. Repetitive binding of the acetylcholine molecules to the same receptors at the muscle endplate B. Diffusion of ... Activation of motor end-plate receptors by neostigmine molecules themselves D. All of the above

Last Answer : D. All of the above

The mechanism by which neostigmine improves contraction of myasthenic muscle involves: A. Repetitive binding of the acetylcholine molecules to the same receptors at the muscle endplate B. Diffusion of acetylcholine released from motor nerve endings to a wider area activating neighbouring receptors C. Activation of motor end-plate receptors by neostigmine molecules themselves D. All of the above

Description : The mechanism by which neostigmine improves contraction of myasthenic muscle involves: A. Repetitive binding of the acetylcholine molecules to the same receptors at the muscle endplate B. Diffusion of ... Activation of motor end-plate receptors by neostigmine molecules themselves D. All of the above

Last Answer : D. All of the above

Aliskiren acts by (A) inhibiting the conversion of Angiotensin I to II (B) inhibiting the release of rennin (C) inhibiting the binding of Angiotensin II to the receptor (D) inhibiting the action of aldosterone

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Last Answer : (B) inhibiting the release of rennin

Humectants added in cosmetic preparations generally act by (A) hydrogen bond formation (B) covalent bond formation (C) complex formation (D) the action of London forces

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The following are true about acetylcholine: a. it has a strong affinity for nicotinic receptors b. is derived from acetyl CoA and choline c. is synthesized by a reaction involving choline acetyltransferase d. all above

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Last Answer : all above

The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are incompletely absorbed after oral administration C. They are devoid of CNS and ocular effects D. Dose to dose they are more potent than atropine

Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine

Last Answer : C. They are devoid of CNS and ocular effects

The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are incompletely absorbed after oral administration C. They are devoid of CNS and ocular effects D. Dose to dose they are more potent than atropine

Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine

Last Answer : C. They are devoid of CNS and ocular effects

The release of acetylcholine is blocked by: a. hemicholinum b. venom of black widow spidec. cocaine d. botulinum toxins r

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Last Answer : botulinum toxins

A patient has been taking digoxin for several years for chronic heart failure is about to receive atropine for another condition. A common effect of digoxin (at therapeutic blood levels) that can be almost entirely blocked by atropine is (a) Decreased appetite (b) Increased atrial contractility (c) Increased PR interval on the ECG (d) Headaches (e) Tachycardia

Description : A patient has been taking digoxin for several years for chronic heart failure is about to receive atropine for another condition. A common effect of digoxin (at therapeutic blood levels) that can ... Increased atrial contractility (c) Increased PR interval on the ECG (d) Headaches (e) Tachycardia

Last Answer : Ans: C

The following are true about the muscarinic receptors: a. they are found at the postganglionic parasympathetic synapses b. they can be selectively blocked by atropine c. M1 muscarinic receptors are found in the brain d. all above

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Last Answer : (D) The Director of Pharmacopoeia Laboratory

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Last Answer : (D) all of the above

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