Description : Allergy is immediate hypersensitivity mediated by _____and mast cell degranulation a) IgG b) IgE c) IgM d) IgA e) IgD
Last Answer : Ans: B
Description : Immunodeficiency: a) A localized protective reaction of tissue to irritation, injury, or infection, characterized by pain, redness, swelling, and sometimes a loss of function b) A disorder or deficiency ... effect and damage the liver. e) It is an immunity disorder which is genetically transferred.
Description : If fever is accompanied by ________, drug toxicity is more likely than allergy and is much more serious. a) Granulocytopenia b) Thrombocytopenia c) Histamine d) Leukopenia e) Hypotension
Last Answer : Ans: A
Description : Answer: b, c, d Eosinophils constitute 1% to 3% of the leukocyte population of the bloodstream. They also reside in tissues and they exhibit phagocytic capabilities. They are less ... the cycle of events that result in recruitment and activation of inflammatory cells at sites of inflammation
Last Answer : Cellular injury from oxidants may be manifest by which of the following? a. Cell membrane lipid peroxidation b. DNA strand breaks c. Cytoskeletal disassembly d. ATP depletion
Description : Which one of the following statements is false ? Allergic asthma is characterized by: a) Response to cyclosporin therapy in severe disease. b) Is characterised by reversible airways obstruction. c) T2 ... fluid. d) Affects 5% of the population. e) Is diagnosed routinely by use of ELISA
Last Answer : Ans: E
Description : Zinc is involved in storage and release of (A) Histamine (B) Acetylcholine (C) Epinephrine (D) Insulin
Last Answer : Answer : D
Description : A mother comes to the pharmacy with her 3-year-old son who has a cough. Which of the following list of symptoms is most likely to indicate an allergy? a) fever b) chesty cough c) rhinorrhoea d) headache e) malaise
Last Answer : Ans: C
Description : Reduction in fever within ___ h withdrawal of drug strongly suggests that suspected drug causing allergy. a) 38 h b) 24h c) 48h d) 16 h e) 20 h
Description : Influenza vaccines can be contraindicated to patients who are allergic to the preservatives of the vaccine, e.g. _____ a) Neomycin b) Streptomycin c) Gentamycin d) Doxycycline e) Clavulanic acid
Description : Penicillin Allergy is usually caused by its chemical degradation to a) Penicillamine b) Penilloic acid c) Penicillenic acid d) Penaldic acid e) Penicilloic acid
Description : Which one of the following is a false statement about atopic eczema? a) It commonly begins by drug reaction. b) Super-added herpes simplex infection is a serious complication. c) The serum IgE ... . d) The skin lesions are typically itchy. e) Treatment with systemic steroids is often necessary.
Description : Delayed allergy reaction (type IV allergic reaction) is: a) An An allergic or immune response that begins within a period lasting from a few minutes to about an hour after exposure to ... of antigen-antibody complexes that cause tissue damage e) An allergic disorder which is transferred genetically.
Description : Immediate allergy reaction (type I allergic reaction) is: a) An allergic or immune response that begins within a period lasting from a few minutes to about an hour after exposure to an ... cause tissue damage e) It occurs during blood transfusion reactions and in hemolytic disease of the newborn.
Description : The primary reason for a physician to prescribe human insulin is that: a) It has a faster onset of action than other insulins b) It has a shorter duration of action than other insulins c ... in preventing the complications of diabetes than animal insulins e) It is more sterile than other insolines.
Description : The organ which involve most frequent hypersensitivity reaction is a) Liver b) Kidney c) Skin d) Lungs e) Stomach
Description : Hypersensitivity refers to undesirable reactions produced by a) circulatory system b) Respiratory system c) Immune System d) Endocrine system e) Autonomic nervous system
Description : Immediate Allergy is what type of hypersensitivity reaction a) Type I Hypersensitivity b) Type II Hypersensitivity c) Type III Hypersensitivity d) Type IV Hypersensitivity e) Type V Hypersensitivity
Description : Which of the following is a prophylactic agent that appears to stabilize mast cells? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Description : Histamine is synthesised in (A) Brain (B) Mast cells (C) Basophils (D) All of these
Description : Histamine (a) May be released from mast cells by a number of therapeutic agents (b) Causes sedation (c) Decreases the force of contraction of ventricular muscle (d) Can cause strong contractions of the gravid human uterus
Last Answer : Ans: D
Description : In mammals, histamine is secreted by (a) lymphocytes (b) mast cells (c) fibroblasts (d) histiocytes.
Last Answer : b) mast cells
Description : Mast cells of connective tissue contain (a) vasopressin and relaxin (b) heparin and histamine (c) heparin and calcitonin (d) serotonin and melanin.
Last Answer : (b) heparin and histamine
Description : Mast cells secrete (a) haemoglobin (b) hippurin (c) myoglobin (d) histamine
Last Answer : (d) histamine.
Description : ________ bind to_________ on microbial invaders. a. Toll-like receptors; PAM Ps b. Mast cells; histamine c. Toll-like receptors; complement d. Macrophages; defensins
Last Answer : a. Toll-like receptors; PAM Ps
Description : The drug that can directly release histamine from mast cells without involving antigen-antibody reaction is: A. Aspirin B. Procaine C. Morphine D. Sulfadiazine
Last Answer : C. Morphine
Description : Following is an example of preformed and not lipid derived mast cell mediator of inflammatory process (a) LTC4 (b) PGD2 (c) PAF (d) Histamine
Description : Which one of the following can be blocked by atropine? (a) Decreased blood pressure caused by hexamethonium (b) Increased blood pressure caused by nicotine (c) Increased skeleton muscle ... by neostigmine (d) Tachycardia caused by exercise (e) Tachycardia caused by infusion of acetylcholine
Description : Match the following columns and select the correct option. Column-I Column - II (A) Eosinophils (i) Immune response (B) Basophils (ii) Phagocytosis (C) Neutrophils (iii) Release histaminase, destructive enzymes (D) Lymphocytes (iv) ... (iii) (c) (i) (ii) (iv) (iii) (d) (ii) (i) (iii) (iv)
Last Answer : (a) (iii) (iv) (ii) (i)
Description : The neurotransmitter agent that is normally released in the sinoatrial node of the heart in response to a blood pressure increase is (a) Acetylcholine (b) Dopamine (c) Epinephrine (d) Glutamate (e) Norepinephrine
Description : Nicotine acts as a stimulant, because it mimics the effect of (a) testosterone (b) dopamine (c) thyroxine (d) acetylcholine.
Last Answer : (d) acetylcholine.
Description : Which of the following hormones is NOT correctly matched with its description? A) thymosin--aids in production of T cells B) thyroxin--needed for growth and development in vertebrates ... by removing glucose into tissues E) epinephrine--released by the adrenal medulla under stressful conditions
Last Answer : D) cortisol--lowers blood glucose level by removing glucose into tissues E) epinephrine--released by the adrenal medulla under stressful conditions
Description : Which one of the following does not act as a neurotransmitter? (a) Cortisone (b) Acetylcholine (c) Epinephrine (d) Norepinephrine
Last Answer : (a) Cortisone
Description : Histamine H2 blockers attenuate the gastric secretory response to acetylcholine and pentagastrin as well because: A. H2 blockers block gastric mucosal cholinergic and gastrin receptors as well B. H2 ... acetylcholine and gastrin all act through the phospholipase C-IP3:DAG pathway in gastric mucosa
Last Answer : C. Acetylcholine and gastrin act partly by releasing histamine in gastric mucosa
Description : Histamine secreting cells are found in (a) connective tissues (b) lungs (c) muscular tissue (d) nervous tissue
Last Answer : (a) connective tissues
Description : During the course of a cellular hypersensitivity a. Antibodies react with antigens in tissues. b. Serotonin and histamine are released by cells. c. Immune complexes form on blood vessel surfaces. d. A skin thickening called an induration may form.
Last Answer : b. Serotonin and histamine are released by cells.
Description : The following statement(s) is/are true concerning host defense mechanisms to intraabdominal infection. a. Bacterial clearance can occur via translymphatic absorption b. Phagocytic activity and bacterial killing can ... may be walled off but are seldom sealed by the omentum and other mobile viscera
Last Answer : Answer: a, b, c The introduction of microorganisms into the normally sterile peritoneal environment invoke several potent specialized host antimicrobial defense mechanisms. Bacterial clearance, ... the contaminated enteric contents walled off, preventing continued soilage of the peritoneal cavity
Description : Proteins that are secreted by cells are generally a. not synthesized on membrane-bound ribosomes b. initially synthesized with a signal peptide or leader sequence at their C terminal c. found in ... endocytosis e. secreted in a form that is larger than the form present in the endoplasmic reticulum
Last Answer : found in vesicles and secretory granules
Description : The symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cell (e) Decreased prostaglandin production
Description : Deep fried food materials are carcinogenic because they are rich in - (1) Fats (2) Hydrocarbons (3) Cooking oil (4) Nicotine
Last Answer : (2) Hydrocarbons Explanation: If foods are overheated or burnt, a group of carcinogenic substances called polycyclic aromatic hydrocarbons (PAHs) are produced. PAHs represent a very large group of ... , PAHs can be absorbed in the intestine and distributed to other organs through blood circulation.
Description : Deep fried food materials are carcinogenic because they are rich in (1) Fats (2) Hydrocarbons (3) Cooking oil (4) Nicotine
Last Answer : Hydrocarbons
Description : Secretory granules are prominent in all of the following EXCEPT: C A. Eosinophils B. Pancreatic islet cells C. Lymphocytes D. None of these
Last Answer : Lymphocytes
Description : Epithelial cells of the intestine involved in food absorption have on their surface (a) pinocytic vesicles (b) microvilli (c) zymogen granules (d) phagocytic vesicles.
Last Answer : (b) microvilli
Description : Acquired immunity consists of humoral immunity maintained by _____ and _____, and cell-mediated immunity controlled by _____ a. T cells, complement, B cells b. T cells, Interleukin, B cells c. B cells, antibodies, T cells d. B cells, histamine, T cells
Last Answer : c. B cells, antibodies, T cells
Description : Cromolyn has as its major action (a) Block of calcium channels in lymphocytes (b) Block of mediator release from mast cells (c) Block of phosphodiesterase in mast cells and basophils (d) Smooth muscle relaxation in the bronchi (e) Stimulation of cortisol release by the adrenals
Description : The Symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cells (e) Decreased prostaglandin production
Description : Methylxanthine drugs such as aminophylline cause which one of the following? (a) Vasoconstriction in many vascular beds (b) Decrease in the amount of cAMP in mast cells (c) Bronchodilation (d) Activation of the enzyme phosphodiesterase (e) Sedation
Description : Tissues are constructed from many distinct cell types that perform different functions in response to signals from each other and the extracellular matrix. During tissue development and tissue regeneration, ... that stem cells undergo when they are required to generate a particular type of cell?
Last Answer : Asymmetric cell division. After asymmetric division, each of the two resulting daughter cells has a unique life course. For example, one daughter cell may differentiate into a specific cell type ( ... cell), whereas the other daughter cell may remain a stem cell with unlimited proliferative ability.
Description : Kashmir Day was first observed in_______ on call of Nawaz Sharif, who was the opposition leader and chief minister of Punjab at the time. A. 1991 B. 1990 C. 1988 D. 1993
Last Answer : ANSWER: A
Description : 36 Kashmir Day was first observed in_______ on call of Nawaz Sharif, who was the opposition leader and chief minister of Punjab at the time. A. 1991 B. 1990 C. 1988 D. 1993