Green papaya latex, which is rich in the main papaya enzyme papain, has been traditionally used by various cultures in Asia to induce a miscarriage during pregnancy. For this purpose it was often applied directly to the uterus, but food forms such as green papaya salad, the seeds of papaya in the parasite killing papaya seed smoothie ahead, as well as supplements containing papain enzyme are best avoided by pregnant women. This warning does not extend to a fully ripe fresh fruit with no green on it. These papaya fruit contain much lower levels of papain and are generally considered very healthy for pregnant women with its rich antioxidant and vitamin content and many other health benefits.