Description : Low doses of adrenaline dilate the following vascular bed: A. Cutaneous B. Mucosal C. Renal D. Skeletal muscle
Last Answer : D. Skeletal muscle
Description : Low doses of adrenaline dilate the following vascular bed (a) Cutaneous (b) Mucosal (c) Renal (d) Skeletal muscle
Last Answer : Ans: D
Description : Blood flow in the following vascular bed generally decreases under the influence of glyceryl trinitrate: A. Coronary B. Cutaneous C. Renal D. Cranial
Last Answer : C. Renal
Description : Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It ... used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation
Last Answer : A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms
Description : Hyoscine differs from atropine in that it: A. Exerts depressant effects on the CNS at relatively low doses B. Exerts more potent effects on the heart than on the eye C. Is longer acting D. Has weaker antimotion sickness activity
Last Answer : A. Exerts depressant effects on the CNS at relatively low doses
Description : Adrenaline injected with a local anaesthetic: A. Reduces local toxicity of the local anaesthetic B. Reduces systemic toxicity of the local anaesthetic C. Shortens duration of local anaesthesia D. Makes the injection less painful
Last Answer : B. Reduces systemic toxicity of the local anaesthetic
Description : Ephedrine is similar to adrenaline in the following feature: A. Potency B. Inability to penetrate blood-brain barrier C. Duration of action D. Producing both α and β adrenergic effects
Last Answer : D. Producing both α and β adrenergic effects
Description : The following action of adrenaline is mediated by both α and β receptors producing the same directional effect: A. Cardiac stimulation B. Intestinal relaxation C. Dilatation of pupil D. Bronchodilatation
Last Answer : B. Intestinal relaxation
Description : The following sympathomimetic amine has agonistic action on α1 + α2 + β1 + β3 adrenoceptors, but not on β2 receptors: A. Adrenaline B. Noradrenaline C. Isoprenaline D. Phenylephrine
Last Answer : B. Noradrenaline
Description : Which is the most important drug in the treatment of organophosphate poisoning: A. Atropine sulfate B. Pralidoxime C. Diazepam D. Adrenaline
Last Answer : A. Atropine sulfate
Description : The following action of adrenaline is not mediated by β receptors: A. Dilatation of blood vessels B. Dilatation of pupil C. Bronchodilation D. Renin release from kidney
Last Answer : B. Dilatation of pupil
Description : The following sympathomimetic amine has agonistic action on α 1 + α 2 + β 1 + β 3 adrenoceptors, but not on β 2 receptors: A. Adrenaline B. Noradrenaline C. Isoprenaline D. Phenylephrine
Description : Fentanyl transdermal patches have been used postoperatively to provide transdermal analgesia. The most dangerous adverse effect of this mode of administration is (a) Cutaneous reactions (b) Diarrhea (c) Hypertension (d) Relaxation of skeletal muscle (e) Respiratory depression
Last Answer : Ans: E
Description : Select the β adrenergic blocker that is primarily eliminated unchanged by renal excretion: A. Propranolol B. Metoprolol C. Esmolol D. Atenolol
Last Answer : D. Atenolol
Description : Select the β adrenergic blocker that is primarily eliminated unchanged by renal excretion: A. Propranolol B. Metoprolol C. Esmolol D. Atenolol Select the β adrenergic blocker that is primarily eliminated unchanged by renal excretion: A. Propranolol B. Metoprolol C. Esmolol D. Atenolol
Description : Muscarinic cholinergic receptors: A. Are located only on parasympathetically innervated effector cells B. Mediate responses by opening an intrinsic Na+ ion channel C. Are present on vascular endothelium which has no cholinergic nerve supply D. Predominate in the autonomic ganglia
Last Answer : C. Are present on vascular endothelium which has no cholinergic nerve supply
Description : The following vascular bed is constricted by caffeine: A. Coronary B. Cutaneous C. Cranial D. Mesenteric
Last Answer : C. Cranial
Description : The following is not a feature of cardioselective beta blockers, when compared to propranolol: A. They are ineffective in suppressing muscle tremor B. They are safer in diabetics C. They are less likely to cause bradycardia D. They are less likely to worsen Raynaud’s disease
Last Answer : C. They are less likely to cause bradycardia
Description : The organ most sensitive to actions of atropine is: A. Gastric glands B. Salivary glands C. Urinary bladder muscle D. Heart
Last Answer : B. Salivary glands
Description : Edrophonium is more suitable for differentiating myasthenic crisis from cholinergic crisis because of its: A. Shorter duration of action B. Longer duration of action C. Direct action on muscle end-plate D. Selective inhibition of true cholinesterase
Last Answer : A. Shorter duration of action
Description : The mechanism by which neostigmine improves contraction of myasthenic muscle involves: A. Repetitive binding of the acetylcholine molecules to the same receptors at the muscle endplate B. Diffusion of ... Activation of motor end-plate receptors by neostigmine molecules themselves D. All of the above
Last Answer : D. All of the above
Description : Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier
Last Answer : C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate
Description : The smooth muscle structure that is relaxed by cholinergic drugs is: A. Colon B. Gastric fundus C. Major bronchi D. Bladder trigone
Last Answer : D. Bladder trigone
Description : Which of the following organs is innervated only by parasympathetic nerves: A. Iris muscles B. Ciliary musclele C. Sweat glands D. Splenic capsu
Last Answer : B. Ciliary musclele
Description : Which of the following organs is innervated only by parasympathetic nerves: A. Iris muscles B. Ciliary muscle C. Sweat glands D. Splenic capsule
Last Answer : B. Ciliary muscle
Description : Which of the following statement(s) is/are correct concerning the cardiovascular response to shock? a. Changes in cardiac contractile function shift the Frank Starling curve up and down b. ... d. The total circulating blood volume is equally split between the arterial and venous system
Last Answer : Answer: a Central in the general cardiovascular response to shock is the action of the heart itself. The principle determinants of cardiac function in the normal heart are the volume of blood ... Blood flow to the skin is sacrificed early, followed by that to the kidneys and splanchnic viscera
Description : Which of the following statements regarding cytokines is incorrect? A. Cytokines act directly on target cells and may potentiate the actions of one another. B. Interleukin 1 (IL-1) ... organ dysfunction syndrome because of its multiple actions and the secondary cascades that it stimulates.
Last Answer : Answer: C DISCUSSION: Cytokines are soluble peptide molecules that are synthesized and secreted by a number of cell types in response to injury, inflammation, and infection. Cytokines, which ... is thought to play a central role in the stress response, particularly in response to endotoxemia
Description : A suspected case of poisoning has been brought to the casualty with weakness, fainting, involuntary passage of urine and stools, profuse sweating, salivation, watering from nose and eyes. His pulse ... likely type of poisoning: A. Belladonna B. Barbiturate C. Anticholinesterase D. Dicophane (DDT
Last Answer : C. Anticholinesterase
Description : To be used as a topically applied ocular beta blocker a drug should have the following properties except: A. Strong local anaesthetic activity B. High lipophilicity C. High ocular capture D. Low systemic activity
Last Answer : A. Strong local anaesthetic activity
Description : A suspected case of poisoning has been brought to the casualty with weakness, fainting, involuntary passage of urine and stools, profuse sweating, salivation, watering from nose and eyes. His pulse ... likely type of poisoning: A. Belladonna B. Barbiturate C. Anticholinesterase D. Dicophane (DDT)
Description : The following tissue is most sensitive to vasopressin: A. Renal collecting ducts B. Intestinal smooth muscle C. Vascular smooth muscle D. Uterus
Last Answer : A. Renal collecting ducts
Description : Select the tissue that is most sensitive to oxytocin: A. Myometrium B. Myoepithelium of mammary alveoli C. Vascular smooth muscle D. Renal collecting ducts
Last Answer : B. Myoepithelium of mammary alveoli
Description : A 68-year-old male who underwent a repair of an abdominal aortic aneurysm 5 days ago, develops tachycardia, tachypnea, hypotension with cool, pale, mottled cyanotic extremities. He ... use of moderate doses of inotropic agents e. Afterload reduction with nitroprusside is absolutely contraindicated
Last Answer : Answer: a, b, d Intrinsic cardiogenic shock results from failure of the heart as an effective pump. Coronary artery disease is the most common cause of myocardial ... hemodynamic monitoring. Infusion of afterload-reducing agents can be administered in conjunction with inotropic support
Description : Select the β-adrenergic blocker that has additional α1 blocking, vasodilator and antioxidant properties: A. Carvedilol B. Celiprolol C. Acebutolol D. Metoprolol
Last Answer : C. Acebutolol
Last Answer : A. Carvedilol
Description : In a patient of myocardial infarction, β adrenergic blockers are used with the following aim/aims: A. To reduce the incidence of reinfarction B. To prevent cardiac arrhythmias C. To limit size of the infarct D. All of the above
Description : Esmolol has the following features except: A. Rapidly developing, shortlasting β adrenergic blockade B. Cardioselectivity of action C. Intrinsic sympathomimetic activity D. Suitability for intraoperative use
Last Answer : C. Intrinsic sympathomimetic activity
Description : Select the ultrashort acting cardioselective β adrenergic blocker: A. Bisoprolol B. Timolol C. Sotalol D. Esmolol
Last Answer : D. Esmolol
Description : β-adrenergic blockers are indicated in the following conditions except: A. Hypertrophic cardiomyopathy B. Congestive heart failure C. Vasospastic angina pectoris D. Dissecting aortic aneurysm
Last Answer : C. Vasospastic angina pectoris
Description : The following disease is worsened by propranolol: A. Glaucoma B. Raynaud’s disease C. Benign prostatic hypertrophy D. Parkinsonism
Last Answer : B. Raynaud’s disease
Description : Select the drug which can impair carbohydrate tolerance in prediabetics but prolongs insulin hypoglycaemia: A. Salbutamol B. Propranolol C. Prazosin D. Nifedipine
Last Answer : B. Propranolol
Description : The β adrenergic blocker having β1 selectivity, intrinsic sympathomimetic activity and membrane stabilizing property is: A. Carvedilol B. Atenolol C. Acebutolol D. Metoprolol
Description : Select the drug which is administered orally for erectile dysfunction in men: A. Yohimbine B. Papaverine C. Alprostadil D. Sildenafil
Last Answer : D. Sildenafil
Description : What is true of sildenafil: A. It enhances sexual enjoyment in normal men B. It delays ejaculation C. It improves penile tumescence in men with erectile dysfunction D. It blocks cavernosal α2 adrenoceptors
Last Answer : C. It improves penile tumescence in men with erectile dysfunction
Description : Sildenafil is contraindicated in patients taking the following class of drugs: A. α-adrenergic blockers B. β-adrenergic blockers C. Organic nitrates D. Angiotensin converting enzyme inhibitors
Last Answer : C. Organic nitrates
Description : Which of the following is a selective α1A receptor blocker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure: A. Terazosin B. Doxazosin C. Trimazosin D. Tamsulosin
Last Answer : D. Tamsulosin