Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It is a synthetic atropine substitute used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation

Choose the correct statement about drotaverine:
A. It is a smooth muscle antispasmodic acting by
non-anticholinergic mechanisms
B. It is a papaverine congener used in peripheral
vascular diseases
C. It is a synthetic atropine substitute used to
control diarrhoea
D. It is a M1/M3 selective antagonist used for
spastic constipation
by

1 Answer

Answer :

A. It is a smooth muscle antispasmodic acting by
non-anticholinergic mechanisms
by

Related questions

Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It is a synthetic atropine substitute used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation

Description : Choose the correct statement about drotaverine: A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms B. It is a papaverine congener used in peripheral vascular diseases C. It ... used to control diarrhoea D. It is a M1/M3 selective antagonist used for spastic constipation

Last Answer : A. It is a smooth muscle antispasmodic acting by non-anticholinergic mechanisms

The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are incompletely absorbed after oral administration C. They are devoid of CNS and ocular effects D. Dose to dose they are more potent than atropine

Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine

Last Answer : C. They are devoid of CNS and ocular effects

Choose the correct statement about sibutramine: A. It is an anorectic drug used to assist weight reduction B. It is an atypical antidepressant C. It is a 5-HT1D receptor antagonist D. Both A and C are correct

Description : Choose the correct statement about sibutramine: A. It is an anorectic drug used to assist weight reduction B. It is an atypical antidepressant C. It is a 5-HT1D receptor antagonist D. Both A and C are correct

Last Answer : A. It is an anorectic drug used to assist weight reduction

Hyoscine differs from atropine in that it: A. Exerts depressant effects on the CNS at relatively low doses B. Exerts more potent effects on the heart than on the eye C. Is longer acting D. Has weaker antimotion sickness activity

Description : Hyoscine differs from atropine in that it: A. Exerts depressant effects on the CNS at relatively low doses B. Exerts more potent effects on the heart than on the eye C. Is longer acting D. Has weaker antimotion sickness activity

Last Answer : A. Exerts depressant effects on the CNS at relatively low doses

The organ most sensitive to actions of atropine is: A. Gastric glands B. Salivary glands C. Urinary bladder muscle D. Heart

Description : The organ most sensitive to actions of atropine is: A. Gastric glands B. Salivary glands C. Urinary bladder muscle D. Heart

Last Answer : B. Salivary glands

Select the drug which is administered orally for erectile dysfunction in men: A. Yohimbine B. Papaverine C. Alprostadil D. Sildenafil

Description : Select the drug which is administered orally for erectile dysfunction in men: A. Yohimbine B. Papaverine C. Alprostadil D. Sildenafil

Last Answer : D. Sildenafil

Select the drug which is administered orally for erectile dysfunction in men: A. Yohimbine B. Papaverine C. Alprostadil D. Sildenafil

Description : Select the drug which is administered orally for erectile dysfunction in men: A. Yohimbine B. Papaverine C. Alprostadil D. Sildenafil

Last Answer : D. Sildenafil

Betaxolol differs from timolol in that it: A. Is a β1 selective blocker B. Is more efficacious in glaucoma C. Produces less ocular side effects D. Is longer acting

Description : Betaxolol differs from timolol in that it: A. Is a β1 selective blocker B. Is more efficacious in glaucoma C. Produces less ocular side effects D. Is longer acting

Last Answer : A. Is a β1 selective blocker

Edrophonium is more suitable for differentiating myasthenic crisis from cholinergic crisis because of its: A. Shorter duration of action B. Longer duration of action C. Direct action on muscle end-plate D. Selective inhibition of true cholinesterase

Description : Edrophonium is more suitable for differentiating myasthenic crisis from cholinergic crisis because of its: A. Shorter duration of action B. Longer duration of action C. Direct action on muscle end-plate D. Selective inhibition of true cholinesterase

Last Answer : A. Shorter duration of action

The smooth muscle structure that is relaxed by cholinergic drugs is: A. Colon B. Gastric fundus C. Major bronchi D. Bladder trigone

Description : The smooth muscle structure that is relaxed by cholinergic drugs is: A. Colon B. Gastric fundus C. Major bronchi D. Bladder trigone

Last Answer : D. Bladder trigone

Low doses of adrenaline dilate the following vascular bed: A. Cutaneous B. Mucosal C. Renal D. Skeletal muscle

Description : Low doses of adrenaline dilate the following vascular bed: A. Cutaneous B. Mucosal C. Renal D. Skeletal muscle

Last Answer : D. Skeletal muscle

Low doses of adrenaline dilate the following vascular bed: A. Cutaneous B. Mucosal C. Renal D. Skeletal muscle

Description : Low doses of adrenaline dilate the following vascular bed: A. Cutaneous B. Mucosal C. Renal D. Skeletal muscle

Last Answer : D. Skeletal muscle

Atropine does not exert relaxant/ antispasmodic effect on the following muscle (a) Intestinal (b) Ureteric (c) Bronchial (d) Layngeal

Description : Atropine does not exert relaxant/ antispasmodic effect on the following muscle (a) Intestinal (b) Ureteric (c) Bronchial (d) Layngeal

Last Answer : Ans: D

Atropine does not exert relaxant/antispasmodic effect on the following muscle: A. Intestinal B. Ureteric C. Bronchial D. Laryngeal

Description : Atropine does not exert relaxant/antispasmodic effect on the following muscle: A. Intestinal B. Ureteric C. Bronchial D. Laryngeal

Last Answer : D. Laryngeal

Atropine does not exert relaxant/antispasmodic effect on the following muscle: A. Intestinal B. Ureteric C. Bronchial D. Laryngeal

Description : Atropine does not exert relaxant/antispasmodic effect on the following muscle: A. Intestinal B. Ureteric C. Bronchial D. Laryngeal

Last Answer : D. Laryngeal

Tetrodotoxin blocks nerve impulse/junctional transmission by: A. Anticholinergic action B. Depleting acetylcholine C. Blocking Na+ channels D. Blocking Ca2+ channels

Description : Tetrodotoxin blocks nerve impulse/junctional transmission by: A. Anticholinergic action B. Depleting acetylcholine C. Blocking Na+ channels D. Blocking Ca2+ channels

Last Answer : C. Blocking Na+ channels

Tetrodotoxin blocks nerve impulse/junctional transmission by: A. Anticholinergic action B. Depleting acetylcholine C. Blocking Na+ channels D. Blocking Ca2+ channels

Description : Tetrodotoxin blocks nerve impulse/junctional transmission by: A. Anticholinergic action B. Depleting acetylcholine C. Blocking Na+ channels D. Blocking Ca2+ channels

Last Answer : C. Blocking Na+ channels

The cardiac muscarinic receptors: A. Are of the M1 subtype B. Are of the M2 subtype C. Are selectively blocked by pirenzepine D. Function through the PIP2 → IP3/DAG pathway

Description : The cardiac muscarinic receptors: A. Are of the M1 subtype B. Are of the M2 subtype C. Are selectively blocked by pirenzepine D. Function through the PIP2 → IP3/DAG pathway

Last Answer : B. Are of the M2 subtype

Choose the drug which is used as a short-term inotropic in severe congestive heart failure and has selective adrenergic β1 agonistic activity but no dopaminergic agonistic activity: A. Dopamine B. Dobutamine C. Amrinone D. Salmeterol

Description : Choose the drug which is used as a short-term inotropic in severe congestive heart failure and has selective adrenergic β1 agonistic activity but no dopaminergic agonistic activity: A. Dopamine B. Dobutamine C. Amrinone D. Salmeterol

Last Answer : B. Dobutamine

Choose the drug which is used as a short-term inotropic in severe congestive heart failure and has selective adrenergic β 1 agonistic activity but no dopaminergic agonistic activity: A. Dopamine B. Dobutamine C. Amrinone D. Salmeterol

Description : Choose the drug which is used as a short-term inotropic in severe congestive heart failure and has selective adrenergic β 1 agonistic activity but no dopaminergic agonistic activity: A. Dopamine B. Dobutamine C. Amrinone D. Salmeterol

Last Answer : B. Dobutamine

Oxytremorine is a selective agonist of muscarinic _______ receptors (a) M1 (b) M2 (c) M3 (d) M4

Description : Oxytremorine is a selective agonist of muscarinic _______ receptors (a) M1 (b) M2 (c) M3 (d) M4

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Choose the selective estrogen receptor modulator that is useful in dysfunctional uterine bleeding by acting as estrogen antagonist in endometrium, but does not alter vaginal epithelium or cervical mucus: A. Ormeloxifene B. Tamoxifen C. Centchroman D. Danazol

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The mydriatic incapable of producing cycloplegia sufficient for refraction testing in children is: A. Atropine B. Hyoscine C. Homatropine D. Cyclopentolate

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The most suitable mydriatic for a patient of corneal ulcer is: A. Atropine sulfate B. Homatropine C. Cyclopentolate D. Tropicamide

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Which of the following mydriatics has the fastest and briefest action: A. Atropine B. Homatropine C. Tropicamide D. Cyclopentolate

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Which is the most important drug in the treatment of organophosphate poisoning: A. Atropine sulfate B. Pralidoxime C. Diazepam D. Adrenaline

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Dobutamine differs from dopamine in that: A. It does not activate peripheral dopaminergic receptors B. It does not activate adrenergic β receptors C. It causes pronounced tachycardia D. It has good blood-brain barrier penetrability

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Dobutamine differs from dopamine in that: A. It does not activate peripheral dopaminergic receptors B. It does not activate adrenergic β receptors C. It causes pronounced tachycardia D. It has good blood-brain barrier penetrability

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Which of the following is a selective α1A receptor blocker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure: A. Terazosin B. Doxazosin C. Trimazosin D. Tamsulosin

Description : Which of the following is a selective α1A receptor blocker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure: A. Terazosin B. Doxazosin C. Trimazosin D. Tamsulosin

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Which of the following is a selective α 1A receptor blocker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure: A. Terazosin B. Doxazosin C. Trimazosin D. Tamsulosin

Description : Which of the following is a selective α 1A receptor blocker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure: A. Terazosin B. Doxazosin C. Trimazosin D. Tamsulosin

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Muscarinic cholinergic receptors: A. Are located only on parasympathetically innervated effector cells B. Mediate responses by opening an intrinsic Na+ ion channel C. Are present on vascular endothelium which has no cholinergic nerve supply D. Predominate in the autonomic ganglia

Description : Muscarinic cholinergic receptors: A. Are located only on parasympathetically innervated effector cells B. Mediate responses by opening an intrinsic Na+ ion channel C. Are present on vascular endothelium which has no cholinergic nerve supply D. Predominate in the autonomic ganglia

Last Answer : C. Are present on vascular endothelium which has no cholinergic nerve supply

Choose the correct statement about nonopioid analgesics: A. All have antiinflammatory property B. All lack dependence producing liability C. All act exclusively at peripheral pain mechanisms D. All inhibit prostaglandin synthesis

Description : Choose the correct statement about nonopioid analgesics: A. All have antiinflammatory property B. All lack dependence producing liability C. All act exclusively at peripheral pain mechanisms D. All inhibit prostaglandin synthesis

Last Answer : B. All lack dependence producing liability

The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are incompletely absorbed after oral administration C. They are devoid of CNS and ocular effects D. Dose to dose they are more potent than atropine

Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine

Last Answer : C. They are devoid of CNS and ocular effects

Select the ultrashort acting cardioselective β adrenergic blocker: A. Bisoprolol B. Timolol C. Sotalol D. Esmolol

Description : Select the ultrashort acting cardioselective β adrenergic blocker: A. Bisoprolol B. Timolol C. Sotalol D. Esmolol

Last Answer : D. Esmolol

Select the longer acting ocular beta blocker: A. Timolol B. Betaxolol C. Cartiolol D. Levobunolol

Description : Select the longer acting ocular beta blocker: A. Timolol B. Betaxolol C. Cartiolol D. Levobunolol

Last Answer : D. Levobunolol

Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors

Description : Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors

Last Answer : B. It is longer acting

Select the ultrashort acting cardioselective β adrenergic blocker: A. Bisoprolol B. Timolol C. Sotalol D. Esmolol

Description : Select the ultrashort acting cardioselective β adrenergic blocker: A. Bisoprolol B. Timolol C. Sotalol D. Esmolol

Last Answer : D. Esmolol

The following is not a feature of cardioselective beta blockers, when compared to propranolol: A. They are ineffective in suppressing muscle tremor B. They are safer in diabetics C. They are less likely to cause bradycardia D. They are less likely to worsen Raynaud’s disease

Description : The following is not a feature of cardioselective beta blockers, when compared to propranolol: A. They are ineffective in suppressing muscle tremor B. They are safer in diabetics C. They are less likely to cause bradycardia D. They are less likely to worsen Raynaud’s disease

Last Answer : C. They are less likely to cause bradycardia

The mechanism by which neostigmine improves contraction of myasthenic muscle involves: A. Repetitive binding of the acetylcholine molecules to the same receptors at the muscle endplate B. Diffusion of acetylcholine released from motor nerve endings to a wider area activating neighbouring receptors C. Activation of motor end-plate receptors by neostigmine molecules themselves D. All of the above

Description : The mechanism by which neostigmine improves contraction of myasthenic muscle involves: A. Repetitive binding of the acetylcholine molecules to the same receptors at the muscle endplate B. Diffusion of ... Activation of motor end-plate receptors by neostigmine molecules themselves D. All of the above

Last Answer : D. All of the above

Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Description : Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier

Last Answer : C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate

Which of the following organs is innervated only by parasympathetic nerves: A. Iris muscles B. Ciliary muscle C. Sweat glands D. Splenic capsule

Description : Which of the following organs is innervated only by parasympathetic nerves: A. Iris muscles B. Ciliary musclele C. Sweat glands D. Splenic capsu

Last Answer : B. Ciliary musclele

The following is not a feature of cardioselective beta blockers, when compared to propranolol: A. They are ineffective in suppressing muscle tremor B. They are safer in diabetics C. They are less likely to cause bradycardia D. They are less likely to worsen Raynaud’s disease

Description : The following is not a feature of cardioselective beta blockers, when compared to propranolol: A. They are ineffective in suppressing muscle tremor B. They are safer in diabetics C. They are less likely to cause bradycardia D. They are less likely to worsen Raynaud’s disease

Last Answer : C. They are less likely to cause bradycardia

Which of the following organs is innervated only by parasympathetic nerves: A. Iris muscles B. Ciliary muscle C. Sweat glands D. Splenic capsule

Description : Which of the following organs is innervated only by parasympathetic nerves: A. Iris muscles B. Ciliary muscle C. Sweat glands D. Splenic capsule

Last Answer : B. Ciliary muscle

Atropine overdose may cause which one of the following (a) Gastrointestinal smooth muscle crampine (b) Increased cardiac rate (c) Increased gastric secretion (d) Pupillary constriction (e) Urinary frequency

Description : Atropine overdose may cause which one of the following (a) Gastrointestinal smooth muscle crampine (b) Increased cardiac rate (c) Increased gastric secretion (d) Pupillary constriction (e) Urinary frequency

Last Answer : Ans: B

The most suitable laxative for a patient of irritable bowel disease with spastic constipation is: A. Dietary fibre B. Liquid paraffin C. Bisacodyl D. Senna

Description : The most suitable laxative for a patient of irritable bowel disease with spastic constipation is: A. Dietary fibre B. Liquid paraffin C. Bisacodyl D. Senna

Last Answer : A. Dietary fibre

Stimulant purgatives are contraindicated in the following: A. Bed ridden patients B. Before abdominal radiography C. Spastic constipation D. Atonic constipation

Description : Stimulant purgatives are contraindicated in the following: A. Bed ridden patients B. Before abdominal radiography C. Spastic constipation D. Atonic constipation

Last Answer : C. Spastic constipation

The following are true about the muscarinic receptors: a. they are found at the postganglionic parasympathetic synapses b. they can be selectively blocked by atropine c. M1 muscarinic receptors are found in the brain d. all above

Description : The following are true about the muscarinic receptors: a. they are found at the postganglionic parasympathetic synapses b. they can be selectively blocked by atropine c. M1 muscarinic receptors are found in the brain d. all above

Last Answer : all above

Which of the following drugs is believed to improve microcirculation in peripheral vascular diseases by promoting RBC flexibility ? (a) Cyclandelate (b) Theophyline (c) Pentoxiphyline (d) Nicotinic acid

Description : Which of the following drugs is believed to improve microcirculation in peripheral vascular diseases by promoting RBC flexibility ? (a) Cyclandelate (b) Theophyline (c) Pentoxiphyline (d) Nicotinic acid

Last Answer : Ans: C

The antihypertensive action of calcium channel blockers is characterized by the following except: A. Delayed onset; blood pressure starts falling after 1–2 weeks therapy B. Lack of central side effects C. No compromise of male sexual function D. Safety in peripheral vascular diseases

Description : The antihypertensive action of calcium channel blockers is characterized by the following except: A. Delayed onset; blood pressure starts falling after 1–2 weeks therapy B. Lack of central side effects C. No compromise of male sexual function D. Safety in peripheral vascular diseases

Last Answer : A. Delayed onset; blood pressure starts falling after 1–2 weeks therapy