Which of the following drugs exhibits ‘therapeutic window’ phenomenon: A. Captopril B. Furosemide C. Diazepam D. Imipramine

Which of the following drugs exhibits ‘therapeutic
window’ phenomenon:
A. Captopril
B. Furosemide
C. Diazepam
D. Imipramine
by

1 Answer

Answer :

D. Imipramine
by

Related questions

Which of the following drugs exhibits ‘therapeutic window’ phenomenon: A. Captopril B. Furosemide C. Diazepam D. Imipramine

Description : Which of the following drugs exhibits ‘therapeutic window’ phenomenon: A. Captopril B. Furosemide C. Diazepam D. Imipramine

Last Answer : D. Imipramine

Compared to the drug named within parenthesis, which of the following drugs has a higher potency but lower efficacy: A. Pethidine (morphine) B. Furosemide (hydrochlorothiazide) C. Diazepam (pentobarbitone) D. Enalapril (captopril)

Description : Compared to the drug named within parenthesis, which of the following drugs has a higher potency but lower efficacy: A. Pethidine (morphine) B. Furosemide (hydrochlorothiazide) C. Diazepam (pentobarbitone) D. Enalapril (captopril)

Last Answer : C. Diazepam (pentobarbitone)

Compared to the drug named within parenthesis, which of the following drugs has a higher potency but lower efficacy: A. Pethidine (morphine) B. Furosemide (hydrochlorothiazide) C. Diazepam (pentobarbitone) D. Enalapril (captopril)

Description : Compared to the drug named within parenthesis, which of the following drugs has a higher potency but lower efficacy: A. Pethidine (morphine) B. Furosemide (hydrochlorothiazide) C. Diazepam (pentobarbitone) D. Enalapril (captopril)

Last Answer : C. Diazepam (pentobarbitone)

The following drug/drugs does/do not produce any overt CNS effect in normal individuals but exert(s) clear cut therapeutic effect at the same dose in the presence of a specific neurological/psychiatric disorder: A. Chlorpromazine B. Levodopa C. Imipramine D. All of the above

Description : The following drug/drugs does/do not produce any overt CNS effect in normal individuals but exert(s) clear cut therapeutic effect at the same dose in the presence of a specific neurological/psychiatric disorder: A. Chlorpromazine B. Levodopa C. Imipramine D. All of the above

Last Answer : B. Levodopa

Diabetic and other types of neuropathic pain often responds to: A. Chlorpromazine B. Diazepam C. Imipramine D. Lithium

Description : Diabetic and other types of neuropathic pain often responds to: A. Chlorpromazine B. Diazepam C. Imipramine D. Lithium

Last Answer : C. Imipramine

Use of potassium sparing diuretics in patients receiving the following drug needs close monitoring: A. Furosemide B. Hydrochlorothiazide C. Captopril D. Verapami

Description : Use of potassium sparing diuretics in patients receiving the following drug needs close monitoring: A. Furosemide B. Hydrochlorothiazide C. Captopril D. Verapami

Last Answer : C. Captopril

A woman in the 28th week of pregnancy has developed pregnancy induced hypertension with a blood pressure reading of 150/100 mm Hg. Select the most appropriate antihypertensive drug for her: A. Furosemide B. Methyldopa C. Propranolol D. Captopril

Description : A woman in the 28th week of pregnancy has developed pregnancy induced hypertension with a blood pressure reading of 150/100 mm Hg. Select the most appropriate antihypertensive drug for her: A. Furosemide B. Methyldopa C. Propranolol D. Captopril

Last Answer : B. Methyldopa

A patient of endogenous depression was put on imipramine therapy. After what interval the therapeutic effect is likely to manifest: A. Three days B. One week C. Three weeks D. Three months

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Last Answer : C. Three weeks

A 55-year-old patient currently receiving other drugs for another condition is to be started on diuretic therapy for mild heart failure. Thiazides are known to reduce the excretion of (a) Diazepam (b) Fluoxetine (c) Imipramine (d) Lithium (e) Potassium

Description : A 55-year-old patient currently receiving other drugs for another condition is to be started on diuretic therapy for mild heart failure. Thiazides are known to reduce the excretion of (a) Diazepam (b) Fluoxetine (c) Imipramine (d) Lithium (e) Potassium

Last Answer : Ans: D

When therapeutic effects decline both below and above a narrow range of doses, a drug is said to exhibit: A. Ceiling effect B. Desensitization C. Therapeutic window phenomenon D. Nonreceptor mediated action

Description : When therapeutic effects decline both below and above a narrow range of doses, a drug is said to exhibit: A. Ceiling effect B. Desensitization C. Therapeutic window phenomenon D. Nonreceptor mediated action

Last Answer : C. Therapeutic window phenomenon

Which of the following drugs attenuates the antihypertensive action of β-blockers: A. Cimetidine B. Indomethacin C. Chlorpromazine D. Imipramine

Description : Which of the following drugs attenuates the antihypertensive action of β-blockers: A. Cimetidine B. Indomethacin C. Chlorpromazine D. Imipramine

Last Answer : B. Indomethacin

Which of the following drugs attenuates the antihypertensive action of β -blockers: A. Cimetidine B. Indomethacin C. Chlorpromazine D. Imipramine

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Last Answer : B. Indomethacin

Thiazide diuretics do not potentiate the antihypertensive action of one of the following drugs: A. Metoprolol B. Nifedipine C. Hydralazine D. Captopril

Description : Thiazide diuretics do not potentiate the antihypertensive action of one of the following drugs: A. Metoprolol B. Nifedipine C. Hydralazine D. Captopril

Last Answer : B. Nifedipine

Drugs effective in bipolar illness include the following except: A. Olanzapine B. Diazepam C. Sodium valproate D. Lamotrigine

Description : Drugs effective in bipolar illness include the following except: A. Olanzapine B. Diazepam C. Sodium valproate D. Lamotrigine

Last Answer : B. Diazepam

Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop of Henle. C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion

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Last Answer : A. Preventing prostaglandin mediated intrarenal haemodynamic actions

Which of the following drugs can afford both haemodynamic improvement as well as disease modifying benefits in CHF: A. Furosemide B. Milrinone C. Losartan D. Digoxin

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Last Answer : C. Losartan

Interaction between the following pair of drugs can be avoided by making suitable adjustments: A. Levodopa and metoclopramide B. Furosemide and indomethacin C. Tetracyclines and ferrous sulfate D. Clonidine and chlorpromazine

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Last Answer : C. Tetracyclines and ferrous sulfate

Concurrent administration of aspirin interacts unfavourably with the following drugs except: A. Furosemide B. Spironolactone C. Codeine D. Methotrexate

Description : Concurrent administration of aspirin interacts unfavourably with the following drugs except: A. Furosemide B. Spironolactone C. Codeine D. Methotrexate

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The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case

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Last Answer : D. They are the preferred drugs in advanced cases

When therapeutic effects decline both below and above a narrow range of doses, a drug is said to exhibit: A. Ceiling effect B. Desensitization C. Therapeutic window phenomenon D. Nonreceptor mediated action

Description : When therapeutic effects decline both below and above a narrow range of doses, a drug is said to exhibit: A. Ceiling effect B. Desensitization C. Therapeutic window phenomenon D. Nonreceptor mediated action

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The side effect of a drug which has been used as a therapeutic effect in another condition is: A. Constipation caused by codeine B. Cough caused by captopril C. Uterine stimulation caused by quinine D. Diarrhoea caused by ampicillin

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The side effect of a drug which has been used as a therapeutic effect in another condition is: A. Constipation caused by codeine B. Cough caused by captopril C. Uterine stimulation caused by quinine D. Diarrhoea caused by ampicillin

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The following drug has been found to improve urine flow in elderly males with benign prostatic hypertrophy: A. Nifedipine B. Prazosin C. Disopyramide D. Imipramine

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Imipramine given to nondepressed individuals produces: A. Euphoria B. Insomnia C. Lethargy and light headedness D. Inappropriate behaviour

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Of the following, choose the antidepressant having both high sedative and high anticholinergic activity: A. Imipramine B. Amitriptyline C. Fluoxetine D. Trazodone

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Last Answer : B. Amitriptyline

Imipramine given to nondepressed individuals produces: A. Euphoria B. Insomnia C. Lethargy and light headedness D. Inappropriate behaviour

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Last Answer : C. Lethargy and light headedness

The drug of choice for trigeminal neuralgia is: A. Aspirin B. Imipramine C. Carbamazepine D. Valproic acid

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Vasomotor reversal phenomenon after administration of an α adrenergic blocker is seen with: A. Adrenaline B. Noradrenaline C. Isoprenaline D. All of the above drugs

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Vasomotor reversal phenomenon after administration of an α adrenergic blocker is seen with: A. Adrenaline B. Noradrenaline C. Isoprenaline D. All of the above drugs

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Last Answer : A. Adrenaline

The following antihypertensive drug tends to lower plasma renin activity: A. Clonidine B. Hydralazine C. Nifedipine D. Captopril

Description : The following antihypertensive drug tends to lower plasma renin activity: A. Clonidine B. Hydralazine C. Nifedipine D. Captopril

Last Answer : A. Clonidine

Used alone the following antihypertensive drug tends to increase cardiac work and can precipitate angina: A. Clonidine B. Hydralazine C. Captopril D. Prazosin

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Last Answer : B. Hydralazine

Loss of taste sensation can be a side effect of the following antihypertensive drug: A. Clonidine B. Captopril C. Verapamil D. Prazosin

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Last Answer : B. Captopril

An elderly hypertensive was treated with hydrochlorothiazide 50 mg daily. Even after a month, his BP was not reduced to the desired level and another antihypertensive was added. After 2 hours of taking the other drug his BP fell precipitously. The most likely other drug given to him is: A. Atenolol B. Captopril C. Methyldopa D. Amlodipine

Description : An elderly hypertensive was treated with hydrochlorothiazide 50 mg daily. Even after a month, his BP was not reduced to the desired level and another antihypertensive was added. After 2 hours of taking the ... likely other drug given to him is: A. Atenolol B. Captopril C. Methyldopa D. Amlodipine

Last Answer : B. Captopril

The following drug increases cardiac output in congestive heart failure without having any direct myocardial action: A. Captopril B. Digoxin C. Amrinone D. Dobutamine

Description : The following drug increases cardiac output in congestive heart failure without having any direct myocardial action: A. Captopril B. Digoxin C. Amrinone D. Dobutamine

Last Answer : A. Captopril

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Last Answer : D. Lisinopri

Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Description : Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Last Answer : C. It is less liable to cause abrupt first dose hypotension

Captopril produces greater fall in blood pressure in: A. Diuretic treated patients B. Patients having low plasma renin activity C. Sodium replete normotensive individuals D. Untreated CHF patient

Description : Captopril produces greater fall in blood pressure in: A. Diuretic treated patients B. Patients having low plasma renin activity C. Sodium replete normotensive individuals D. Untreated CHF patient

Last Answer : A. Diuretic treated patients

Captopril pretreatment: A. Inhibits the pressor action of angiotensin I B. Inhibits the pressor action of angiotensin II C. Potentiates the depressor action of bradykinin D. Both ‘A’ and ‘C’ are correct

Description : Captopril pretreatment: A. Inhibits the pressor action of angiotensin I B. Inhibits the pressor action of angiotensin II C. Potentiates the depressor action of bradykinin D. Both ‘A’ and ‘C’ are correct

Last Answer : D. Both ‘A’ and ‘C’ are correct

Loss or alteration of taste sensation can occur a side effect of: A. Levodopa B. Captopril C. Penicillamine D. All of the above

Description : Loss or alteration of taste sensation can occur a side effect of: A. Levodopa B. Captopril C. Penicillamine D. All of the above

Last Answer : D. All of the above

The following statement(s) is/are correct in relation to diazepam and chlorpromazine: A. Both have anticonvulsant property B. Both do not carry abuse liability C. Both have antianxiety action D. All of the above are correc

Description : The following statement(s) is/are correct in relation to diazepam and chlorpromazine: A. Both have anticonvulsant property B. Both do not carry abuse liability C. Both have antianxiety action D. All of the above are correc

Last Answer : C. Both have antianxiety action

Select the drug which should not be used to treat neurotic anxiety and tension syndromes despite having antianxiety action: A. Buspirone B. Chlorpromazine C. Diazepam D. Alprazolam

Description : Select the drug which should not be used to treat neurotic anxiety and tension syndromes despite having antianxiety action: A. Buspirone B. Chlorpromazine C. Diazepam D. Alprazolam

Last Answer : B. Chlorpromazine

The following drug is not likely to produce dependence: A. Diazepam B. Chlorpromazine C. Pethidine D. Methadone

Description : The following drug is not likely to produce dependence: A. Diazepam B. Chlorpromazine C. Pethidine D. Methadone

Last Answer : B. Chlorpromazine

The preferred drug for status epilepticus is: A. Intravenous diazepam B. Intravenous phenytoin sodium C. Intramuscular phenobarbitone D. Rectal diazepam

Description : The preferred drug for status epilepticus is: A. Intravenous diazepam B. Intravenous phenytoin sodium C. Intramuscular phenobarbitone D. Rectal diazepam

Last Answer : A. Intravenous diazepam

A 3-year-old boy gets seizures whenever he develops fever. Which is the most appropriate strategy so that he does not develop febrile convulsions: A. Treat fever with paracetamol and do not give any anticonvulsant drug B. Continuous phenobarbitone prophylaxis till the age of 10 years C. Continuous diazepam prophylaxis for 3 years D. Intermittent diazepam prophylaxis started at the onset of fever

Description : A 3-year-old boy gets seizures whenever he develops fever. Which is the most appropriate strategy so that he does not develop febrile convulsions: A. Treat fever with paracetamol and ... Continuous diazepam prophylaxis for 3 years D. Intermittent diazepam prophylaxis started at the onset of fever

Last Answer : D. Intermittent diazepam prophylaxis started at the onset of fever

Despite having anticonvulsant action, diazepam is not used in the treatment of epilepsy because: A. It is not effective orally B. It causes sedation C. Its anticonvulsant action wanes off with chronic use D. Both ‘B’ and ‘C’ are correct

Description : Despite having anticonvulsant action, diazepam is not used in the treatment of epilepsy because: A. It is not effective orally B. It causes sedation C. Its anticonvulsant action wanes off with chronic use D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

The preferred drug for suppressing febrile convulsions is: A. Intramuscular phenobarbitone B. Intravenous phenytoin C. Rectal diazepam D. Oral sodium valproate

Description : The preferred drug for suppressing febrile convulsions is: A. Intramuscular phenobarbitone B. Intravenous phenytoin C. Rectal diazepam D. Oral sodium valproate

Last Answer : C. Rectal diazepam

Select the correct statement about flumazenil: A. It is a CNS stimulant used as an antidote for benzodiazepine poisoning B. It is a CNS depressant but blocks the action of diazepam C. It has no CNS effect of its own but blocks the depressant effects of benzodiazepines as well as barbiturates D. It has no CNS effect of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines

Description : Select the correct statement about flumazenil: A. It is a CNS stimulant used as an antidote for benzodiazepine poisoning B. It is a CNS depressant but blocks the action of diazepam C. It has ... of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines

Last Answer : D. It has no CNS effect of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines

The following drug is used to reverse the CNS depression produced by diazepam: A. Dexamphetamine B. Doxapram C. Physostigmine D. Flumazenil

Description : The following drug is used to reverse the CNS depression produced by diazepam: A. Dexamphetamine B. Doxapram C. Physostigmine D. Flumazenil

Last Answer : D. Flumazenil