Description : Select the drug having a narrow spectrum antiepileptic activity restricted to absence seizures: A. Lamotrigine B. Ethosuccimide C. Sodium valproate D. Primidone
Last Answer : . Ethosuccimide
Description : The preferred drug for suppressing febrile convulsions is: A. Intramuscular phenobarbitone B. Intravenous phenytoin C. Rectal diazepam D. Oral sodium valproate
Last Answer : C. Rectal diazepam
Description : An epileptic woman controlled by phenytoin therapy conceives. Which of the following measures is most appropriate: A. Medical termination of pregnancy B. Withdraw phenytoin therapy C. ... lowest effective level D. Substitute phenytoin with a combination of carbamazepine and sodium valproate
Last Answer : C. Gradually reduce phenytoin dose to the lowest effective level
Description : he antiepileptic drug which suppresses maximal electroshock as well as kindled seizures, raises pentylenetetrazol threshold and is effective in both generalized tonic-clonic as well as absence seizures is: A. Phenytoin B. Carbamazepine C. Sodium valproate D. Ethosuximide
Last Answer : C. Sodium valproate
Description : Olanzapine has the following features except: A. It is an antipsychotic drug with weak D2 receptor blocking action B. It has potent 5-HT2 blocking and antimuscarinic actions C. It lowers seizure threshold D. It produces prominent extrapyramidal side effects
Last Answer : D. It produces prominent extrapyramidal side effect
Description : Which one of the followings is used as a mood stabilizer for bipolar disorder and also in certain epileptic convulsions? (A) Phenytoin (B) Lithium (C) Sodium valproate (D) Fluoxetine
Last Answer : (C) Sodium valproate
Description : Which of the following is the most suitable drug for a 6-year-old girl suffering from absence seizures with occasional generalized tonic-clonic seizures: A. Ethosuccimide B. Sodium valproate C. Carbamazepine D. Phenytoin
Last Answer : B. Sodium valproate
Description : Sodium valproate should be used with caution in young children because they are particularly at risk of developing the following adverse effect: A. Hepatitis B. Loss of hair C. Anorexia D. Tremor
Last Answer : A. Hepatitis
Description : Sodium valproate has been shown to: A. Prolong neuronal Na+ channel inactivation B. Attenuate ‘T’ type Ca2+ current in neurones C. Inhibit degradation of GABA by GABA-transaminase D. All of the above
Last Answer : D. All of the above
Description : The following antiepileptic drug is likely to cause hyponatremia as a side effect, especially in elderly patients: A. Primidone B. Carbamazepine C. Phenytoin D. Sodium valproate
Last Answer : B. Carbamazepine
Description : The following drug displaces plasma protein bound phenytoin as well as decreases its metabolism: A. Carbamazepine B. Sodium valproate C. Cimetidine D. Chloramphenicol
Description : The distinctive features of fluoxetine compared to the typical tricyclic antidepressants include the following except: A. It is less likely to produce cardiac arrhythmias in overdose B. It infrequently ... suffering from chronic somatic illness D. It does not block neuronal uptake of biogenic amines
Last Answer : D. It does not block neuronal uptake of biogenic amines
Description : The following drug can be used as an alternative to lithium in mania and bipolar illness: A. Carbamazepine B. Carisoprodol C. Clomipramine D. Diethyl carbamazine
Last Answer : A. Carbamazepine
Description : Which of the following drugs exhibits ‘therapeutic window’ phenomenon: A. Captopril B. Furosemide C. Diazepam D. Imipramine
Last Answer : D. Imipramine
Description : The following is true of procainamide except: A. It generates an active metabolite in the body B. Its plasma half-life is longer than that of quinidine C. On long-term use, it ... erythematosus like illness D. It is effective in many cases of ventricular extrasystoles, not responding to lignocaine
Last Answer : A. Disopyramide
Description : Which of the following is a high potency antipsychotic drug having minimal sedative and autonomic effects and no propensity to cause weight gain: A. Chlorpromazine B. Triflupromazine C. Haloperidol D. Olanzapine
Last Answer : C. Haloperido
Description : Which of the following is an atypical neuroleptic drug: A. Loxapine B. Olanzapine C. Pimozide D. Flupenthixol
Last Answer : B. Olanzapin
Description : The preferred drug for status epilepticus is: A. Intravenous diazepam B. Intravenous phenytoin sodium C. Intramuscular phenobarbitone D. Rectal diazepam
Last Answer : A. Intravenous diazepam
Description : Residual CNS depression is least marked after the use of the following anaesthetic: A. Diazepam B. Thiopentone sodium C. Lorazepam D. Propofo
Last Answer : D. Propofol
Description : Select the antiepileptic drug that in addition is a preferred treatment for post herpetic neuralgia and pain due to diabetic neuropathy: A. Carbamazepine B. Gabapentin C. Lamotrigine D. Primidone
Last Answer : B. Gabapentin
Description : Choose the correct statement about lamotrigine: A. It is a dopaminergic agonist used in parkinsonism B. It acts by blocking NMDA-type of glutamate receptors C. It is a broad spectrum antiepileptic drug D. It suppresses tonic-clonic seizures, but worsens absence seizures
Last Answer : C. It is a broad spectrum antiepileptic drug
Description : Diazepam is indicated in the following conditions except: A. Generalized tonic-clonic (grand mal) epilepsy B. Tetanus C. Febrile convulsions D. Cardiac catheterization
Last Answer : A. Generalized tonic-clonic (grand mal) epilepsy
Description : Despite having anticonvulsant action, diazepam is not used in the treatment of epilepsy because: A. It is not effective orally B. It causes sedation C. Its anticonvulsant action wanes off with chronic use D. Both ‘B’ and ‘C’ are correct
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : The drugs used to treat Mycobact. avium complex infection in AIDS patients include the following except: A. Isoniazid B. Clarithromycin C. Ethambutol D. Ciprofloxacin
Last Answer : A. Isoniazid
Description : First line antitubercular drugs include the following except: A. Ciprofloxacin B. Streptomycin C. Pyrazinamide D. Ethambutol
Last Answer : A. Ciprofloxacin
Description : Indications for the use of antiplatelet drugs include the following except: A. Secondary prophylaxis of myocardial infarction B. Unstable angina pectoris C. Disseminated intravascular coagulation D. Stroke prevention in patients with transient ischaemic attacks
Last Answer : C. Disseminated intravascular coagulation
Description : Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal ... . They do not worsen blood lipid profile D. They do not impair work performance
Last Answer : B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs
Description : 16.8 Drugs that suppress growth hormone release in acromegaly include the following except: A. Bromocriptine B. Somatostatin C. Octreotide D. Nafarelin
Last Answer : D. Nafarelin
Description : The constellation of adverse effects associated with nonsteroidal antiinflammatory drugs include the following except: A. Sedation B. Gastric irritation C. Fluid retention D. Rashes
Last Answer : A. Sedation
Description : Drug/drugs effective in filariasis include: A. Ivermectin B. Albendazole C. Diethyl carbamazine citrate D. All of the above
Description : The following drugs are effective in systemic mycosis except: A. Terbinafine B. Itraconazole C. Ketoconazole D. Fluconazol
Last Answer : A. Terbinafine
Description : The following is true of proton pump inhibitors except: A. They are the most effective drugs for Zolinger Ellison syndrome B. Their prolonged use can cause atrophy of gastric mucosa C. They inhibit growth of H. pylori in stomach D. They have no effect on gastric motilit
Last Answer : B. Their prolonged use can cause atrophy of gastric mucosa
Description : The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case
Last Answer : D. They are the preferred drugs in advanced cases
Description : The uses of sodium/potassium iodide include the following except: A. Preoperative preparation of Grave’s disease patient B. Prophylaxis of endemic goiter C. As antiseptic D. As expectorant
Last Answer : C. As antiseptic
Description : Antimicrobials effective against anaerobic bacteria include the following except: A. Tobramycin B. Clindamicin C. Chloramphenicol D. Metronidazole
Last Answer : A. Tobramycin
Description : Selective inhibition of conditioned avoidance response in animals by a drug indicates that the drug is likely to be effective in: A. Anxiety B. Major depression C. Schizophrenia D. Manic-depressive illness
Last Answer : C. Schizophrenia
Description : Select the antiepileptic drug that is effective in manicdepressive illness as well: A. Ethosuccimide B. Primidone C. Phenobarbitone D. Carbamazepine
Last Answer : D. Carbamazepine
Description : Diabetic and other types of neuropathic pain often responds to: A. Chlorpromazine B. Diazepam C. Imipramine D. Lithium
Last Answer : C. Imipramine
Description : The following statement(s) is/are correct in relation to diazepam and chlorpromazine: A. Both have anticonvulsant property B. Both do not carry abuse liability C. Both have antianxiety action D. All of the above are correc
Last Answer : C. Both have antianxiety action
Description : Select the drug which should not be used to treat neurotic anxiety and tension syndromes despite having antianxiety action: A. Buspirone B. Chlorpromazine C. Diazepam D. Alprazolam
Last Answer : B. Chlorpromazine
Description : The following drug is not likely to produce dependence: A. Diazepam B. Chlorpromazine C. Pethidine D. Methadone
Description : A 3-year-old boy gets seizures whenever he develops fever. Which is the most appropriate strategy so that he does not develop febrile convulsions: A. Treat fever with paracetamol and ... Continuous diazepam prophylaxis for 3 years D. Intermittent diazepam prophylaxis started at the onset of fever
Last Answer : D. Intermittent diazepam prophylaxis started at the onset of fever
Description : Select the correct statement about flumazenil: A. It is a CNS stimulant used as an antidote for benzodiazepine poisoning B. It is a CNS depressant but blocks the action of diazepam C. It has ... of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines
Last Answer : D. It has no CNS effect of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines
Description : The following drug is used to reverse the CNS depression produced by diazepam: A. Dexamphetamine B. Doxapram C. Physostigmine D. Flumazenil
Last Answer : D. Flumazenil
Description : Zolpidem differs from diazepam in that: A. It is safer in overdose than diazepam B. Its hypnotic action shows little fading on repeated nightly use C. It causes more marked suppression of REM sleep D. It has more potent muscle relaxant action
Last Answer : B. Its hypnotic action shows little fading on repeated nightly use
Description : At a single hypnotic dose, the pharmacokinetics of diazepam is characterised by: A. Slow elimination and little redistribution B. Slow elimination with marked redistribution C. Rapid elimination and marked redistribution D. Ultra rapid elimination
Last Answer : B. Slow elimination with marked redistribution
Description : Select the drug that antagonises diazepam action noncompetitively: A. Adenosine B. Flumazenil C. Bicuculline D. Valproic acid
Last Answer : C. Bicuculline
Description : Hypnotic dose of diazepam produces the following action: A. Tachycardia B. Constipation C. Hyperalgesia D. Decreased nocturnal gastric secretion
Last Answer : D. Decreased nocturnal gastric secretion
Description : Select the anaesthetic that increases cardiac output and blood pressure: A. Halothane B. Fentanyl C. Ketamine D. Diazepam
Last Answer : C. Ketamine
Description : Diazepam is used as a muscle relaxant for: A. Deep intra-abdominal operation B. Tracheal intubation C. Tetanus D. Diagnosis of myasthenia gravis
Last Answer : C. Tetanus