Select the correct statement about flumazenil: A. It is a CNS stimulant used as an antidote for benzodiazepine poisoning B. It is a CNS depressant but blocks the action of diazepam C. It has no CNS effect of its own but blocks the depressant effects of benzodiazepines as well as barbiturates D. It has no CNS effect of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines

Select the correct statement about flumazenil:
A. It is a CNS stimulant used as an antidote for
benzodiazepine poisoning
B. It is a CNS depressant but blocks the action
of diazepam
C. It has no CNS effect of its own but blocks the
depressant effects of benzodiazepines as well
as barbiturates
D. It has no CNS effect of its own but blocks the
depressant effect of diazepam as well as stimulant effect of beta carbolines
by

1 Answer

Answer :

D. It has no CNS effect of its own but blocks the
depressant effect of diazepam as well as stimulant effect of beta carbolines
by

Related questions

The mechanism of action of barbiturates differs from that of benzodiazepines in that they: A. Do not affect the GABA-benzodiazepine receptor-chloride channel complex B. Act as inverse agonists at the benzodiazepine receptor C. Increase the frequency of chloride channel opening without affecting its life time D. Have both GABA-facilitatory as well as GABA-mimetic actions

Description : The mechanism of action of barbiturates differs from that of benzodiazepines in that they: A. Do not affect the GABA-benzodiazepine receptor-chloride channel complex B. Act as inverse agonists at the ... without affecting its life time D. Have both GABA-facilitatory as well as GABA-mimetic actions

Last Answer : D. Have both GABA-facilitatory as well as GABA-mimetic actions

Select the correct statement about benzodiazepines (BZDs): A. All BZDs facilitate GABA mediated Cl¯ influx into neurones B. Different BZDs exert the same degrees of hypnotic, anxiolytic and anticonvulsant actions C. The BZD receptor is homogeneous at all neuronal sites D. The muscle relaxant action of BZDs is not blocked by flumazenil

Description : Select the correct statement about benzodiazepines (BZDs): A. All BZDs facilitate GABA mediated Cl¯ influx into neurones B. Different BZDs exert the same degrees of hypnotic, anxiolytic and anticonvulsant ... at all neuronal sites D. The muscle relaxant action of BZDs is not blocked by flumazenil

Last Answer : A. All BZDs facilitate GABA mediated Cl¯ influx into neurones

The following drug is used to reverse the CNS depression produced by diazepam: A. Dexamphetamine B. Doxapram C. Physostigmine D. Flumazenil

Description : The following drug is used to reverse the CNS depression produced by diazepam: A. Dexamphetamine B. Doxapram C. Physostigmine D. Flumazenil

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Select the drug that antagonises diazepam action noncompetitively: A. Adenosine B. Flumazenil C. Bicuculline D. Valproic acid

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elect the drug which relieves anxiety but neither reacts with benzodiazepine receptor nor produces any overt CNS effect: A. Oxazepam B. Thioproperazine C. Buspirone D. Chlordiazepoxide

Description : elect the drug which relieves anxiety but neither reacts with benzodiazepine receptor nor produces any overt CNS effect: A. Oxazepam B. Thioproperazine C. Buspirone D. Chlordiazepoxide

Last Answer : C. Buspirone

Hyoscine differs from atropine in that it: A. Exerts depressant effects on the CNS at relatively low doses B. Exerts more potent effects on the heart than on the eye C. Is longer acting D. Has weaker antimotion sickness activity

Description : Hyoscine differs from atropine in that it: A. Exerts depressant effects on the CNS at relatively low doses B. Exerts more potent effects on the heart than on the eye C. Is longer acting D. Has weaker antimotion sickness activity

Last Answer : A. Exerts depressant effects on the CNS at relatively low doses

Which of the following statements is not true of zopiclone: A. It is a nonbenzodiazepine hypnotic with efficacy and safety similar to benzodiazepines B. It does not produce rebound sleep disturbances on discontinuation C. It does not act by potentiating GABA D. It is used to wean off insomniacs from regular benzodiazepine use

Description : Which of the following statements is not true of zopiclone: A. It is a nonbenzodiazepine hypnotic with efficacy and safety similar to benzodiazepines B. It does not produce rebound sleep disturbances ... act by potentiating GABA D. It is used to wean off insomniacs from regular benzodiazepine use

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Benzodiazepines differ from barbiturates in the following aspects except: A. They have a steeper dose response curve B. They have higher therapeutic index C. They have lower abuse liability D. They do not induce microsomal drug metabolizing enzymes

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Last Answer : A. They have a steeper dose response curve

What is TRUE about Benzodiazepine and diazepam in 5-10mg oral dose used for oral sedation in dentistry: A. Good analgesic effect if given 1 hour prior to dental sessions B. Would be reversed by flumazepil because it is a Benzodiazepam C. Post operative headache D. There is a profound amnesic action and no side affects

Description : What is TRUE about Benzodiazepine and diazepam in 5-10mg oral dose used for oral sedation in dentistry: A. Good analgesic effect if given 1 hour prior to dental sessions B. Would be reversed ... Benzodiazepam C. Post operative headache D. There is a profound amnesic action and no side affects

Last Answer : B. Would be reversed by flumazepil because it is a Benzodiazepam

Barbiturates exert the following actions except: A. Anticonvulsant B. Analgesic C. Antianxiety D. Respiratory depressant

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Last Answer : B. Analgesic

Which of the following is not a CNS depressant but increases the tendency to fall asleep at night: A. Pyridoxine B. Diphenhydramine C. Melatonin D. Ethanol

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Last Answer : C. Melatonin

Residual CNS depression is least marked after the use of the following anaesthetic: A. Diazepam B. Thiopentone sodium C. Lorazepam D. Propofo

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What is NOT TRUE in relation to the prescription of 5mg or 10mg of diazepam for sedation?check A. Patient commonly complain of post operative headache T B. An acceptable level of anxiolytic action is obtained when the drug is given one hour preoperatively T C. There is a profound amnesic action and no side affects not sure D. Active metabolites can give a level of sedation up to 8 hours post operatively T E. As Benzodiazepine the action can be reversed with FlumazepilNE T

Description : What is NOT TRUE in relation to the prescription of 5mg or 10mg of diazepam for sedation?check A. Patient commonly complain of post operative headache T B. An acceptable level of anxiolytic ... to 8 hours post operatively T E. As Benzodiazepine the action can be reversed with FlumazepilNE T

Last Answer : C. There is a profound amnesic action and no side affects not sure

Choose the ergot alkaloid that is well absorbed orally, has weak vascular but prominent uterine stimulant action: A. Ergometrine B. Ergotamine C. Dihydroergotamine D. Dihydroergotoxine

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Last Answer : A. Ergometrine

The following is true of fenfluramine except: A. It lacks CNS stimulant action B. Its use has been associated with cardiac abnormalities and pulmonary hypertension C. It causes weight loss independent of reduced food intake D. It enhances serotonergic transmission in the brain

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Last Answer : C. It causes weight loss independent of reduced food intake

Hyoscine differs from atropine in that it (a) Exerts depressant effects on the CNS at relatively low doses (b) Exerts more potent effects on the heart than on the eye (c) Is longer acting (d) Has weaker antimotion sickness activity

Description : Hyoscine differs from atropine in that it (a) Exerts depressant effects on the CNS at relatively low doses (b) Exerts more potent effects on the heart than on the eye (c) Is longer acting (d) Has weaker antimotion sickness activity

Last Answer : Ans: A

Hyoscine differs from atropine in that it: A. Exerts depressant effects on the CNS at relatively low doses B. Exerts more potent effects on the heart than on the eye C. Is longer acting D. Has weaker antimotion sickness activity

Description : Hyoscine differs from atropine in that it: A. Exerts depressant effects on the CNS at relatively low doses B. Exerts more potent effects on the heart than on the eye C. Is longer acting D. Has weaker antimotion sickness activity

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The antidote of choice for morphine poisoning is: A. Nalorphine B. Nalbuphine C. Naltrexone D. Naloxone

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The most effective antidote for belladonna poisoning is: A. Neostigmine B. Physostigmine C. Pilocarpine D. Methacholine

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The most effective antidote for belladonna poisoning is: A. Neostigmine B. Physostigmine C. Pilocarpine D. Methacholine

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As antihypertensives the thiazide diuretics have the following advantages except: A. High ceiling antihypertensive action B. Absence of CNS side effects C. Absence of tolerance development D. Low cost

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Last Answer : A. High ceiling antihypertensive action

The following statement is correct about buspirone: A. It interacts with benzodiazepine receptor as an inverse agonist B. It is a rapidly acting anxiolytic, good for panic states C. It produces physical dependence and suppresses barbiturate withdrawal syndrome D. It has anxiolytic but no anticonvulsant or muscle relaxant propert

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Select the drug which should not be used to treat neurotic anxiety and tension syndromes despite having antianxiety action: A. Buspirone B. Chlorpromazine C. Diazepam D. Alprazolam

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Choose the drug that has been found to be more selective for the ω1 subtype of BZD receptor, and produces hypnotic action but little antianxiety, muscle relaxant or anticonvulsant actions: A. Zopiclone B. Zolpidem C. Flumazenil D. Melatonin

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The following is a competitive antagonist of GABA but a noncompetitive antagonist of diazepam: A. Picrotoxin B. Muscimol C. Flumazenil D. Bicuculline

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The following is a competitive antagonist of GABA but a noncompetitive antagonist of diazepam: A. Picrotoxin B. Muscimol C. Flumazenil D. Bicuculline

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The following statement(s) is/are correct in relation to diazepam and chlorpromazine: A. Both have anticonvulsant property B. Both do not carry abuse liability C. Both have antianxiety action D. All of the above are correc

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The following statement is not correct for uremic patients: A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened B. Pethidine can cause seizures C. Diazepam produces exaggerated CNS depression D. Tetracyclines further raise blood urea level

Description : The following statement is not correct for uremic patients: A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened B. Pethidine can cause seizures C. Diazepam produces exaggerated CNS depression D. Tetracyclines further raise blood urea level

Last Answer : A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened

The following statement is not correct for uremic patients: A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened B. Pethidine can cause seizures C. Diazepam produces exaggerated CNS depression D. Tetracyclines further raise blood urea level

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Last Answer : A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened

Ranitidine differs from cimetidine in the following respect: A. It is less potent B. It is shorter acting C. It does not have antiandrogenic action D. It produces more CNS side effect

Description : Ranitidine differs from cimetidine in the following respect: A. It is less potent B. It is shorter acting C. It does not have antiandrogenic action D. It produces more CNS side effect

Last Answer : C. It does not have antiandrogenic action

The major constraint in the long term use of benzodiazepines for treatment of generalized anxiety disorder is: A. Development of tolerance to antianxiety action of the benzodiazepines B. Possibility of drug dependence C. Cardiovascular depression D. Likelyhood of overdose toxicit

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Last Answer : B. Possibility of drug dependence

The following drugs exert their action through the GABAA-benzodiazepine–receptor Cl¯ channel complex except: A. Baclofen B. Zolpidem C. Bicuculline D. Phenobarbitone

Description : The following drugs exert their action through the GABAA-benzodiazepine–receptor Cl¯ channel complex except: A. Baclofen B. Zolpidem C. Bicuculline D. Phenobarbitone

Last Answer : A. Baclofen

Despite having anticonvulsant action, diazepam is not used in the treatment of epilepsy because: A. It is not effective orally B. It causes sedation C. Its anticonvulsant action wanes off with chronic use D. Both ‘B’ and ‘C’ are correct

Description : Despite having anticonvulsant action, diazepam is not used in the treatment of epilepsy because: A. It is not effective orally B. It causes sedation C. Its anticonvulsant action wanes off with chronic use D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

Is marijuana a stimulant or a depressant?

Description : Is marijuana a stimulant or a depressant?

Last Answer : It chillaxes you. I don’t think it would make you hyper unless it was laced with something!

Alcohol is a common - (a) stimulant (b) depressant (c) hallucinogen (d) none of these

Description : Alcohol is a common - (a) stimulant (b) depressant (c) hallucinogen (d) none of these

Last Answer : Ans:(b)

Which is the particular type of drug that is obtained from the plant whose one flowering branch is shown here? (a) Hallucinogen (b) Depressant (c) Stimulant (d) Pain killer

Description : Which is the particular type of drug that is obtained from the plant whose one flowering branch is shown here? (a) Hallucinogen (b) Depressant (c) Stimulant (d) Pain killer

Last Answer : (a) Hallucinogen

Select the correct statement about Naloxone: A. It equally blocks μ, κ and δ opioid receptors B. It blocks μ receptors at lower doses than those needed for others C. It blocks κ receptors at lower doses than those needed for others D. It blocks δ receptors at lower doses than those needed for others

Description : Select the correct statement about Naloxone: A. It equally blocks μ, κ and δ opioid receptors B. It blocks μ receptors at lower doses than those needed for others C. It blocks κ receptors at lower doses than those needed for others D. It blocks δ receptors at lower doses than those needed for others

Last Answer : B. It blocks μ receptors at lower doses than those needed for others

The anaesthetic action of thiopentone sodium is characterised by: A. Good muscle relaxation B. Poor analgesia C. Sensitization of heart to adrenaline D. No postoperative residual CNS depression

Description : The anaesthetic action of thiopentone sodium is characterised by: A. Good muscle relaxation B. Poor analgesia C. Sensitization of heart to adrenaline D. No postoperative residual CNS depression

Last Answer : B. Poor analgesia

Select the prokinetic-antiemetic drug which at relatively higher doses blocks both dopamine D2 as well as 5-HT3 receptors and enhances acetylcholine release from myenteric neurones: A. Cisapride B. Prochlorperazine C. Metoclopramide D. Domperidon

Description : Select the prokinetic-antiemetic drug which at relatively higher doses blocks both dopamine D2 as well as 5-HT3 receptors and enhances acetylcholine release from myenteric neurones: A. Cisapride B. Prochlorperazine C. Metoclopramide D. Domperidon

Last Answer : C. Metoclopramide

Out of two anticholinesterases, drug ‘X’ is a tertiary amine while drug ‘Y’ is a quarternary ammonium compound. Then: A. Drug ‘X’ is likely to be more potent than ‘Y’ B. Drug ‘X’ will be more suitable to be used as a miotic C. Drug ‘Y’ will be completely metabolized in the body D. Drug ‘Y’ will produce CNS effects

Description : Out of two anticholinesterases, drug X' is a tertiary amine while drug Y' is a quarternary ammonium compound. Then: A. Drug X' is likely to be more potent than Y' B. Drug X' will be more ... a miotic C. Drug Y' will be completely metabolized in the body D. Drug Y' will produce CNS effects

Last Answer : B. Drug ‘X’ will be more suitable to be used as a miotic

The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are incompletely absorbed after oral administration C. They are devoid of CNS and ocular effects D. Dose to dose they are more potent than atropine

Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine

Last Answer : C. They are devoid of CNS and ocular effects

Select the anaesthetic that increases cardiac output and blood pressure: A. Halothane B. Fentanyl C. Ketamine D. Diazepam

Description : Select the anaesthetic that increases cardiac output and blood pressure: A. Halothane B. Fentanyl C. Ketamine D. Diazepam

Last Answer : C. Ketamine

The following drug/drugs does/do not produce any overt CNS effect in normal individuals but exert(s) clear cut therapeutic effect at the same dose in the presence of a specific neurological/psychiatric disorder: A. Chlorpromazine B. Levodopa C. Imipramine D. All of the above

Description : The following drug/drugs does/do not produce any overt CNS effect in normal individuals but exert(s) clear cut therapeutic effect at the same dose in the presence of a specific neurological/psychiatric disorder: A. Chlorpromazine B. Levodopa C. Imipramine D. All of the above

Last Answer : B. Levodopa

Zolpidem differs from diazepam in that: A. It is safer in overdose than diazepam B. Its hypnotic action shows little fading on repeated nightly use C. It causes more marked suppression of REM sleep D. It has more potent muscle relaxant action

Description : Zolpidem differs from diazepam in that: A. It is safer in overdose than diazepam B. Its hypnotic action shows little fading on repeated nightly use C. It causes more marked suppression of REM sleep D. It has more potent muscle relaxant action

Last Answer : B. Its hypnotic action shows little fading on repeated nightly use

Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Description : Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Last Answer : C. It is less liable to cause abrupt first dose hypotension

Hypnotic dose of diazepam produces the following action: A. Tachycardia B. Constipation C. Hyperalgesia D. Decreased nocturnal gastric secretion

Description : Hypnotic dose of diazepam produces the following action: A. Tachycardia B. Constipation C. Hyperalgesia D. Decreased nocturnal gastric secretion

Last Answer : D. Decreased nocturnal gastric secretion

Select the correct statement from the ones given below. (a) Barbiturates, when given to criminals, make them tell the truth. (b) Morphine is often given to persons, who have undergone surgery, as a pain killer. (c) Chewing tobacco lowers blood pressure and heart rate. (d) Cocaine is given to patients after surgery as it stimulates recovery.

Description : Select the correct statement from the ones given below. (a) Barbiturates, when given to criminals, make them tell the truth. (b) Morphine is often given to persons, who have undergone surgery, ... pressure and heart rate. (d) Cocaine is given to patients after surgery as it stimulates recovery.

Last Answer : (b) Morphine is often given to persons, who have undergone surgery, as a pain killer.

Hypnotic benzodiazepines increase the period of time spent in the following stage of sleep: A. Stage II B. Stage III C. Stage IV D. REM stage

Description : Hypnotic benzodiazepines increase the period of time spent in the following stage of sleep: A. Stage II B. Stage III C. Stage IV D. REM stage

Last Answer : A. Stage II

Clobazam is a benzodiazepine used as: A. Hypnotic B. Muscle relaxant C. Anxiolytic D. Antiepileptic

Description : Clobazam is a benzodiazepine used as: A. Hypnotic B. Muscle relaxant C. Anxiolytic D. Antiepileptic

Last Answer : D. Antiepileptic

The following is a very potent and short acting benzodiazepine whose use as hypnotic has been noted to cause psychiatric disturbances in some cases: A. Flurazepam B. Nitrazepam C. Temazepam D. Triazolam

Description : The following is a very potent and short acting benzodiazepine whose use as hypnotic has been noted to cause psychiatric disturbances in some cases: A. Flurazepam B. Nitrazepam C. Temazepam D. Triazolam

Last Answer : D. Triazolam