Description : Pilocarpine is used for: A. Glaucoma B. Paralytic ileus C. Urinary retention D. All of the above
Last Answer : A. Glaucoma
Description : A 3-year-old child was given one tablet three times a day to control loose motions. The diarrhoea stopped but next day the child was brought in a toxic condition with abdominal ... drug could have caused this condition: A. Iodochlorhydroxyquinoline B. Furazolidone C. Loperamide D. Metronidazole
Last Answer : C. Loperamide
Description : Actions of pilocarpine include the following except: A. Sweating B. Salivation C. Miosis D. Cycloplegia
Last Answer : D. Cycloplegia
Description : The following disease is worsened by propranolol: A. Glaucoma B. Raynaud’s disease C. Benign prostatic hypertrophy D. Parkinsonism
Last Answer : B. Raynaud’s disease
Description : Select the diuretic that is most effective in acute congestive glaucoma: A. Indapamide B. Amiloride C. Mannitol D. Furosemide
Last Answer : C. Mannitol
Description : Betaxolol differs from timolol in that it: A. Is a β1 selective blocker B. Is more efficacious in glaucoma C. Produces less ocular side effects D. Is longer acting
Last Answer : A. Is a β1 selective blocker
Description : The organ most sensitive to actions of atropine is: A. Gastric glands B. Salivary glands C. Urinary bladder muscle D. Heart
Last Answer : B. Salivary glands
Description : A direct-acting cholinomimetic that is lipid-soluble and often used in the treatment of glaucoma is (a) Acetylcholine (b) Bethanechol (c) Physostigmine (d) Pilocarpine (e) Neostigmine
Last Answer : Ans: D
Description : Timolol eye drops are preferred over pilocarpine eye drops by glaucoma patients because: A. Timolol is more effective than pilocarpine B. Timolol acts by enhancing uveo-scleral outflow C. Timolol produces less ocular side effects D. There are no contraindications to timolol
Last Answer : C. Timolol produces less ocular side effects
Description : Pilocarpine reduces intraocular tension in open angle glaucoma by: A. Contracting sphincter pupillae B. Increasing tone of ciliary muscle C. Reducing aqueous formation D. Enhancing uveo-scleral outflow
Last Answer : B. Increasing tone of ciliary muscle
Description : Select the β-adrenergic blocker that has additional α1 blocking, vasodilator and antioxidant properties: A. Carvedilol B. Celiprolol C. Acebutolol D. Metoprolol
Last Answer : C. Acebutolol
Last Answer : A. Carvedilol
Description : In a patient of myocardial infarction, β adrenergic blockers are used with the following aim/aims: A. To reduce the incidence of reinfarction B. To prevent cardiac arrhythmias C. To limit size of the infarct D. All of the above
Last Answer : D. All of the above
Description : Select the β adrenergic blocker that is primarily eliminated unchanged by renal excretion: A. Propranolol B. Metoprolol C. Esmolol D. Atenolol
Last Answer : D. Atenolol
Description : The following is not a feature of cardioselective beta blockers, when compared to propranolol: A. They are ineffective in suppressing muscle tremor B. They are safer in diabetics C. They are less likely to cause bradycardia D. They are less likely to worsen Raynaud’s disease
Last Answer : C. They are less likely to cause bradycardia
Description : Esmolol has the following features except: A. Rapidly developing, shortlasting β adrenergic blockade B. Cardioselectivity of action C. Intrinsic sympathomimetic activity D. Suitability for intraoperative use
Last Answer : C. Intrinsic sympathomimetic activity
Description : Select the ultrashort acting cardioselective β adrenergic blocker: A. Bisoprolol B. Timolol C. Sotalol D. Esmolol
Last Answer : D. Esmolol
Description : β-adrenergic blockers are indicated in the following conditions except: A. Hypertrophic cardiomyopathy B. Congestive heart failure C. Vasospastic angina pectoris D. Dissecting aortic aneurysm
Last Answer : C. Vasospastic angina pectoris
Description : Select the drug which can impair carbohydrate tolerance in prediabetics but prolongs insulin hypoglycaemia: A. Salbutamol B. Propranolol C. Prazosin D. Nifedipine
Last Answer : B. Propranolol
Description : The β adrenergic blocker having β1 selectivity, intrinsic sympathomimetic activity and membrane stabilizing property is: A. Carvedilol B. Atenolol C. Acebutolol D. Metoprolol
Description : Select the drug which is administered orally for erectile dysfunction in men: A. Yohimbine B. Papaverine C. Alprostadil D. Sildenafil
Last Answer : D. Sildenafil
Description : What is true of sildenafil: A. It enhances sexual enjoyment in normal men B. It delays ejaculation C. It improves penile tumescence in men with erectile dysfunction D. It blocks cavernosal α2 adrenoceptors
Last Answer : C. It improves penile tumescence in men with erectile dysfunction
Description : Sildenafil is contraindicated in patients taking the following class of drugs: A. α-adrenergic blockers B. β-adrenergic blockers C. Organic nitrates D. Angiotensin converting enzyme inhibitors
Last Answer : C. Organic nitrates
Description : Which of the following is a selective α1A receptor blocker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure: A. Terazosin B. Doxazosin C. Trimazosin D. Tamsulosin
Last Answer : D. Tamsulosin
Description : The primary reason for preferring phentolamine as the α adrenergic blocker for performing diagnostic test for pheochromocytoma is: A. It produces rapid and short lasting α-adrenergic blockade B. It equally ... It is the most potent α blocker D. It has no additional β adrenergic blocking property
Last Answer : A. It produces rapid and short lasting α-adrenergic blockade
Description : The bladder trigone and prostatic muscles are relaxed by: A. Adrenergic α1 agonists B. Adrenergic α1 antagonists C. Adrenergic α2 agonists D. Adrenergic α2 antagonists
Last Answer : B. Adrenergic α1 antagonists
Description : The drug which produces vasoconstriction despite being an α adrenergic blocker is: A. Phenoxybenzamine B. Ergotamine C. Dihydroergotoxine D. Tolazoline
Last Answer : B. Ergotamine
Description : The nonselective α adrenergic blockers produce the following actions except: A. Postural hypotension B. Bradycardia C. Miosis D. Inhibition of ejaculation
Last Answer : B. Bradycardia
Description : Adrenaline injected with a local anaesthetic: A. Reduces local toxicity of the local anaesthetic B. Reduces systemic toxicity of the local anaesthetic C. Shortens duration of local anaesthesia D. Makes the injection less painful
Last Answer : B. Reduces systemic toxicity of the local anaesthetic
Description : Vasoconstrictors should not be used in: A. Neurogenic shock B. Haemorrhagic shock C. Secondary shock D. Hypotension due to spinal anaesthesia
Last Answer : C. Secondary shock
Description : Choose the correct statement about sibutramine: A. It is an anorectic drug used to assist weight reduction B. It is an atypical antidepressant C. It is a 5-HT1D receptor antagonist D. Both A and C are correct
Last Answer : A. It is an anorectic drug used to assist weight reduction
Description : The following is true of fenfluramine except: A. It lacks CNS stimulant action B. Its use has been associated with cardiac abnormalities and pulmonary hypertension C. It causes weight loss independent of reduced food intake D. It enhances serotonergic transmission in the brain
Last Answer : C. It causes weight loss independent of reduced food intake
Description : Which of the following drugs has been used both as orally active nasal decongestant as well as appetite suppressant, and has been implicated in precipitating haemorrhagic stroke: A. Dexfenfluramine B. Phenylpropanolamine C. Isoxsuprine D. Oxymetazoline
Last Answer : B. Phenylpropanolamine
Description : Ephedrine is similar to adrenaline in the following feature: A. Potency B. Inability to penetrate blood-brain barrier C. Duration of action D. Producing both α and β adrenergic effects
Last Answer : D. Producing both α and β adrenergic effects
Description : Choose the drug which is used as a short-term inotropic in severe congestive heart failure and has selective adrenergic β1 agonistic activity but no dopaminergic agonistic activity: A. Dopamine B. Dobutamine C. Amrinone D. Salmeterol
Last Answer : B. Dobutamine
Description : Dobutamine differs from dopamine in that: A. It does not activate peripheral dopaminergic receptors B. It does not activate adrenergic β receptors C. It causes pronounced tachycardia D. It has good blood-brain barrier penetrability
Last Answer : A. It does not activate peripheral dopaminergic receptors
Description : Dopaminergic D1 and D2 as well as adrenergic α and β1, but not β2 receptors are activated by: A. Dopamine B. Dobutamine C. Methoxamine D. Phenylephrine
Last Answer : A. Dopamine
Description : Noradrenaline is administered by: A. Subcutaneous injection B. Intramuscular injection C. Slow intravenous infusion D. All of the above routes
Last Answer : C. Slow intravenous infusion
Description : Low doses of adrenaline dilate the following vascular bed: A. Cutaneous B. Mucosal C. Renal D. Skeletal muscle
Last Answer : D. Skeletal muscle
Description : The following action of adrenaline is mediated by both α and β receptors producing the same directional effect: A. Cardiac stimulation B. Intestinal relaxation C. Dilatation of pupil D. Bronchodilatation
Last Answer : B. Intestinal relaxation
Description : The following sympathomimetic amine has agonistic action on α1 + α2 + β1 + β3 adrenoceptors, but not on β2 receptors: A. Adrenaline B. Noradrenaline C. Isoprenaline D. Phenylephrine
Last Answer : B. Noradrenaline
Description : A sympathomimetic amine that acts almost exclusively by releasing noradrenaline from the nerve endings is: A. Ephedrine B. Dopamine C. Isoprenaline D. Tyramine
Last Answer : D. Tyramine
Description : The principal process which terminates the action of noradrenaline released from adrenergic nerve ending is: A. Degradation by MAO B. Methylation by COMT C. Axonal uptake D. Extraneuronal uptake
Last Answer : C. Axonal uptake
Description : The following type/types of noradrenaline uptake is blocked by reserpine: A. Axonal uptake B. Granular uptake C. Extraneuronal uptake D. All of the above
Last Answer : B. Granular uptake
Description : Tyramine induces release of noradrenaline from adrenergic nerve endings: A. By depolarizing the axonal membrane B. By mobilizing Ca2+ C. By a nonexocytotic process D. Only in the presence of MAO inhibitors
Last Answer : C. By a nonexocytotic process
Description : The most efficacious inhibitor of catecholamine synthesis in the body is: A. α-methyl-p-tyrosine B. α-methyldopa C. α-methyl-norepinephrine D. Entacapone
Last Answer : A. α-methyl-p-tyrosine