Description : Pilocarpine reduces intraocular tension in open angle glaucoma by: A. Contracting sphincter pupillae B. Increasing tone of ciliary muscle C. Reducing aqueous formation D. Enhancing uveo-scleral outflow
Last Answer : B. Increasing tone of ciliary muscle
Description : Timolol eye drops are preferred over pilocarpine eye drops by glaucoma patients because: A. Timolol is more effective than pilocarpine B. Timolol acts by enhancing uveo-scleral outflow C. Timolol produces less ocular side effects D. There are no contraindications to timolol
Last Answer : C. Timolol produces less ocular side effects
Description : The site of action of miotics for therapeutic effect in angle closure glaucoma is: A. Canal of Schlemm B. Ciliary body C. Ciliary muscle D. Sphincter pupillae muscle
Last Answer : D. Sphincter pupillae muscle
Description : Beta adrenergic blockers lower intraocular tension by: A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors B. Constricting ciliary blood vessels ... action on trabecular meshwork D. Reducing aqueous formation unrelated to beta adrenoceptor mediation
Last Answer : A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors
Description : Which of the following categories of medications increases aqueous fluid outflow in the patient with glaucoma? a) Cholinergics Cholinergics increase aqueous fluid outflow by contracting ... production. d) Carbonic anhydrase inhibitors Carbonic anhydrase inhibitors decrease aqueous humor production.
Last Answer : a) Cholinergics Cholinergics increase aqueous fluid outflow by contracting the ciliary muscle, causing miosis, and opening the trabecular meshwork.
Description : The effects of topically applied anticholinesterase on the eye include: a. conjunctival hyperaemia b. raised intraocular pressure c. ciliary muscle contraction d. sphincter pupillae muscle relaxation e. retraction of the upper lids
Last Answer : ciliary muscle contraction
Description : Agonistic action on which of the following adrenergic receptors located on ciliary epithelial cells reduces aqueous secretion: A. β1 receptor B. β2 receptor C. α1 receptor D. α2 receptor
Last Answer : D. α2 receptor
Description : The ciliary ganglion: a. is found between the optic nerve and the medial rectus b. contains sympathetic nerve that supplies the sphincter pupillae c. is a parasympathetic relay ganglion for fibers from ... nucleus d. contains sensory nerve e. has a motor nerve that goes to the inferior oblique
Last Answer : is a parasympathetic relay ganglion for fibers from the Edinger-Westphal nucleus
Description : Pilocarpine is used for: A. Glaucoma B. Paralytic ileus C. Urinary retention D. All of the above
Last Answer : A. Glaucoma
Description : Currently, the first choice drug for open angle glaucoma is: A. Miotic eye drops B. Ocular α2 adrenergic agonists C. Ocular prostaglandin analogues D. Ocular β adrenergic blockers
Last Answer : D. Ocular β adrenergic blockers
Description : Actions of pilocarpine include the following except: A. Sweating B. Salivation C. Miosis D. Cycloplegia
Last Answer : D. Cycloplegia
Description : Dantrolene sodium reduces skeletal muscle tone by: A. Reducing acetylcholine release from motor nerve endings B. Suppressing spinal polysynaptic reflexes C. Inhibiting the generation of muscle action potential D. Reducing Ca2+ release from sarcoplasmic reticulum in the muscle fibre
Last Answer : D. Reducing Ca2+ release from sarcoplasmic reticulum in the muscle fibre
Description : Select the drug(s) which afford(s) relief in gastroesophageal reflux by increasing lower esophageal sphincter tone and promoting gastric emptying, but without affecting acidity of gastric contents: A. Sodium alginate B. Metoclopramide C. Cisapride D. Both ‘B’ and ‘C
Last Answer : D. Both ‘B’ and ‘C’
Description : Betaxolol differs from timolol in that it: A. Is a β1 selective blocker B. Is more efficacious in glaucoma C. Produces less ocular side effects D. Is longer acting
Last Answer : A. Is a β1 selective blocker
Description : A direct-acting cholinomimetic that is lipid-soluble and often used in the treatment of glaucoma is (a) Acetylcholine (b) Bethanechol (c) Physostigmine (d) Pilocarpine (e) Neostigmine
Last Answer : Ans: D
Description : Best site where intraocular lens is fitted: a. Capsular ligament b. Endosulcus c. Ciliary supported d. Capsular bag
Last Answer : ANSWER: D
Description : A 60-year-old woman has glaucoma following cataract surgery. Which of the following can be used to reduce intraocular pressure? (a) Leukotriene LTD4 or its analogs (b) Prostaglandin E2 or its analogs ( ... analogs (d) Slow-reacting substance of anaplylaxis (SRS-A) (e) Thromboxane A2 or its analogs
Last Answer : Ans: C
Description : The intraocular pressure: a. shows a higher diurnal variation in glaucoma patients b. is highest in the morning c. gives a falsely higher reading in patients with thick cornea d. all
Last Answer : all
Description : Which of the following terms refers to the decrease in lens flexibility that occurs with age, resulting in the near point of focus getting farther away? a) Presbyopia Presbyopia usually begins in ... lens of the eye. d) Glaucoma Glaucoma is a disease characterized by increased intraocular pressure.
Last Answer : a) Presbyopia Presbyopia usually begins in the fifth decade of life, when reading glasses are required to magnify objects.
Description : After 48 hours of a cataract extraction operation, a patient complained of ocular pain and visual loss. On examination, this eye looked red with ciliary injection, corneal oedema and absent red ... a. Secondary glaucoma. b. Anterior uveitis. c. Bacterial endophthalmitis. d. Acute conjunctivitis
Last Answer : ANSWER: C
Description : One of the following statements about muscular responses is not true. Choose that one (a) A muscle fibre contracts in all-or-none fashion (b) There is a slight latent period that occurs between when ... contraction (d) When a person is fully at rest, none of the muscles are contracting in the body
Last Answer : Ans:(d)
Description : ndicate the drug which does not improve lower esophageal sphincter tone or prevent gastroesophageal reflux, but is used as first line treatment of gastroesophageal reflux disease: A. Sodium alginate + aluminium hydroxide gel B. Omeprazole C. Mosapride D. Famotidine
Last Answer : B. Omeprazole
Description : Metoclopramide has the following actions except: A. Increases lower esophageal sphincter tone B. Increases tone of pyloric sphincter C. Increases gastric peristalsis D. Increases intestinal peristalsis
Last Answer : B. Increases tone of pyloric sphincter
Description : In parkinsonian patients levodopa exerts the following effects except: A. Reduces skeletal muscle contractility B. Decreases muscle tone C. Increases locomotor activity D. Inhibits muscle tremor
Last Answer : A. Reduces skeletal muscle contractility
Description : A. It is a clonidine congener used in spasticity due to stroke or spinal injury B. It reduces muscle tone by activating GABAB receptors C. It inhibits release of excitatory amino-acids in spinal interneurones D. It reduces muscle spasms without producing weaknes
Last Answer : B. It reduces muscle tone by activating GABAB receptors
Description : Which adverse drug effect is more common in children than in adults: A. Isoniazid induced neuropathy B. Chlorpromazine induced muscle dystonia C. Digoxin induced cardiac arrhythmia D. Penicillin hypersensitivity
Last Answer : B. Chlorpromazine induced muscle dystonia
Description : Edrophonium is more suitable for differentiating myasthenic crisis from cholinergic crisis because of its: A. Shorter duration of action B. Longer duration of action C. Direct action on muscle end-plate D. Selective inhibition of true cholinesterase
Last Answer : A. Shorter duration of action
Description : The mechanism by which neostigmine improves contraction of myasthenic muscle involves: A. Repetitive binding of the acetylcholine molecules to the same receptors at the muscle endplate B. Diffusion of ... Activation of motor end-plate receptors by neostigmine molecules themselves D. All of the above
Last Answer : D. All of the above
Description : Neostigmine is preferred over physostigmine for treating myasthenia gravis because: A. It is better absorbed orally B. It has longer duration of action C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate D. It penetrates blood-brain barrier
Last Answer : C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate
Description : The smooth muscle structure that is relaxed by cholinergic drugs is: A. Colon B. Gastric fundus C. Major bronchi D. Bladder trigone
Last Answer : D. Bladder trigone
Description : Which of the following is an idiosyncratic adverse drug reaction: A. Muscle dystonia caused by triflupromazine B. Insomnia after taking pentobarbitone C. Precipitation of asthma by morphine D. Gum hyperplasia caused by phenytoin
Last Answer : B. Insomnia after taking pentobarbitone
Description : Which of the following adverse drug reactions is due to a specific genetic abnormality: A. Tetracycline induced sunburn like skin lesions B. Quinidine induced thrombocytopenia C. Metoclopramide induced muscle dystonia D. Primaquine induced massive haemolysis
Last Answer : D. Primaquine induced massive haemolysis
Description : In patients with benign prostatic hypertrophy, finasteride exerts the following action/actions: A. Reduces size of the prostate gland B. Increases peak urinary flow rate C. Relaxes vesical sphincter D. Both 'A' and 'B' are correct
Last Answer : D. Both 'A' and 'B' are correct
Description : Agonists affect the receptor molecule in the following manner: A. Alter its amino acid sequence B. Denature the receptor protein C. Alter its folding or alignment of subunits D. Induce covalent bond formation
Last Answer : C. Alter its folding or alignment of subunits
Description : If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation
Last Answer : A. More than the glomerular filtration rate
Description : The following are true about tight junction: a. it forms a barrier to water b. it is found in the blood-aqueous barrier of the ciliary body c. it is found in the blood-retinal barrier at the apex of the retinal pigment epithelium d. all above
Last Answer : all above
Description : Parts A, B, C and D of the human eye are shown in the diagram. Select the option which gives correct identification along with its functions characteristics. (a) C-Aqueous chamber-Reflects the light which does not ... , i.e., rods and cones. (d) B - Blind spot-Has only a few rods and cones.
Last Answer : (c) A - Retina - Contains photoreceptors, i.e., rods and cones.
Description : Aqueous humour is formed by: a. Epithelium of ciliary body b. Posterior surface of iris c. Lens d. Pars plana
Last Answer : ANSWER: A
Description : Ergometrine stops postpartum haemorrhage by: A. Causing vasoconstriction of uterine arteries B. Increasing tone of uterine muscle C. Promoting coagulation D. Inducing platelet aggregation
Last Answer : B. Increasing tone of uterine muscle
Description : Atropine is contraindicated in: A. Pulmonary embolism B. Digitalis toxicity C. Iridocyclitis D. Raised intraocular tension
Last Answer : D. Raised intraocular tension
Description : Apraclonidine is a clonidine congener which is used: A. To suppress opioid withdrawal syndrome B. To suppress menopausal syndrome C. As Analgesic D. To reduce intraocular tension
Last Answer : D. To reduce intraocular tension
Description : Detergents dissolved in water help in cleaning clothes by A. Increasing the temperature of water B. Reacting chemically with dirt C. Reducing the surface tension of water D. Dissolving dirt