Which of the following is a long acting neuroleptic having specific antidopaminergic action, but little adrenergic or cholinergic blocking activity: A. Triflupromazine B. Thioridazine C. Clozapine D. Pimozide

Which of the following is a long acting neuroleptic
having specific antidopaminergic action, but little
adrenergic or cholinergic blocking activity:
A. Triflupromazine
B. Thioridazine
C. Clozapine
D. Pimozide
by

1 Answer

Answer :

D. Pimozide
by

Related questions

Clozapine is considered to be an atypical neuroleptic because: A. It has weak antidopaminergic action but high antipsychotic efficacy B. Its side effect profile is different from that of chlorpromazine C. It is not a phenothiazine derivative D. Both ‘A’ and ‘B’ are correct

Description : Clozapine is considered to be an atypical neuroleptic because: A. It has weak antidopaminergic action but high antipsychotic efficacy B. Its side effect profile is different from that of chlorpromazine C. It is not a phenothiazine derivative D. Both ‘A’ and ‘B’ are correct

Last Answer : D. Both ‘A’ and ‘B’ are correct

The following antipsychotic drug has weak dopamine D2 but additional 5-HT2 blocking activity and benefits both positive and negative symptoms of schizophrenia: A. Loxapine B. Clozapine C. Pimozide D. Penfluridol

Description : The following antipsychotic drug has weak dopamine D2 but additional 5-HT2 blocking activity and benefits both positive and negative symptoms of schizophrenia: A. Loxapine B. Clozapine C. Pimozide D. Penfluridol

Last Answer : B. Clozapin

Choose the phenothiazine compound which has selective labyrinthine suppressant action, is used for vomiting and vertigo, but not in schizophrenia: A. Triflupromazine B. Prochlorperazine C. Trifluoperazine D. Thioridazine

Description : Choose the phenothiazine compound which has selective labyrinthine suppressant action, is used for vomiting and vertigo, but not in schizophrenia: A. Triflupromazine B. Prochlorperazine C. Trifluoperazine D. Thioridazine

Last Answer : B. Prochlorperazine

The antipsychotic drug most likely to cause ocular toxicity on long-term use is: A. Thioridazine B. Haloperidol C. Flupenthixol D. Pimozide

Description : The antipsychotic drug most likely to cause ocular toxicity on long-term use is: A. Thioridazine B. Haloperidol C. Flupenthixol D. Pimozide

Last Answer : A. Thioridazine

Procainamide differs from quinidine in the following respect(s): A. It does not cause paradoxical tachycardia B. It has no α adrenergic blocking activity C. It has little antivagal action D. Both ‘B’ and ‘C’ are corre

Description : Procainamide differs from quinidine in the following respect(s): A. It does not cause paradoxical tachycardia B. It has no α adrenergic blocking activity C. It has little antivagal action D. Both ‘B’ and ‘C’ are corre

Last Answer : D. Both ‘B’ and ‘C’ are correct

Procainamide differs from quinidine in the following respect(s): A. It does not cause paradoxical tachycardia B. It has no α adrenergic blocking activity C. It has little antivagal action D. Both ‘B’ and ‘C’ are correct

Description : Procainamide differs from quinidine in the following respect(s): A. It does not cause paradoxical tachycardia B. It has no α adrenergic blocking activity C. It has little antivagal action D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

Blockade of both dopamine D2 and serotonin 5-HT2A/2C receptors is a distinctive feature of: A. Pimozide B. Haloperidol C. Ketanserin D. Clozapine

Description : Blockade of both dopamine D2 and serotonin 5-HT2A/2C receptors is a distinctive feature of: A. Pimozide B. Haloperidol C. Ketanserin D. Clozapine

Last Answer : D. Clozapine

Choose the correct statement(s) about dofetilide: A. It is a pure class III antiarrhythmic B. It has no adrenergic/cholinergic receptor blocking property C. It selectively depresses the rapid component of delayed rectifier K+ current in myocardial fibres D. All of the above

Description : Choose the correct statement(s) about dofetilide: A. It is a pure class III antiarrhythmic B. It has no adrenergic/cholinergic receptor blocking property C. It selectively depresses the rapid component of delayed rectifier K+ current in myocardial fibres D. All of the above

Last Answer : D. All of the above

Which of the following is an atypical neuroleptic drug: A. Loxapine B. Olanzapine C. Pimozide D. Flupenthixol

Description : Which of the following is an atypical neuroleptic drug: A. Loxapine B. Olanzapine C. Pimozide D. Flupenthixol

Last Answer : B. Olanzapin

What is true of risperidone: A. It is an atypical neuroleptic which produces few extrapyramidal side effects B. It has combined dopamine D2 and 5-HT2 receptor blocking activity C. It does not cause hyperprolactinemia D. Both 'A' and 'B' are correct

Description : What is true of risperidone: A. It is an atypical neuroleptic which produces few extrapyramidal side effects B. It has combined dopamine D2 and 5-HT2 receptor blocking activity C. It does not cause hyperprolactinemia D. Both 'A' and 'B' are correct

Last Answer : D. Both 'A' and 'B' are correct

The following is a tetracyclic antidepressant that has additional dopamine blocking and neuroleptic properties, as well as greater propensity to cause seizures in overdose: A. Amoxapine B. Doxepin C. Dothiepin D. Trazodone

Description : The following is a tetracyclic antidepressant that has additional dopamine blocking and neuroleptic properties, as well as greater propensity to cause seizures in overdose: A. Amoxapine B. Doxepin C. Dothiepin D. Trazodone

Last Answer : A. Amoxapine

Procainamide differs from quinidine in the following respect (a) It does not cause paradoxical tachycardia (b) It has no alfa adrenergic blocking activity (c) It has little antivagal action (d) Both (b) and (c) Ans: D 68. In heart, potassium channels determine (a) Pacemaker function (b) Resting potential (c) Action potential duration (d) All of the above

Description : Procainamide differs from quinidine in the following respect (a) It does not cause paradoxical tachycardia (b) It has no alfa adrenergic blocking activity (c) It has little antivagal action (d) Both (b ... a) Pacemaker function (b) Resting potential (c) Action potential duration (d) All of the above

Last Answer : Ans: D

The following drug claimed to have a therapeutic effect in senile dementia has α adrenergic blocking activity: A. Piracetam B. Pyritinol C. Codergocrine D. Methylphenidate

Description : The following drug claimed to have a therapeutic effect in senile dementia has α adrenergic blocking activity: A. Piracetam B. Pyritinol C. Codergocrine D. Methylphenidate

Last Answer : C. Codergocrine

Labetalol has: A. More potent β adrenergic blocking than α blocking activity B. More potent α adrenergic blocking than β blocking activity C. Equal α and β adrenergic blocking activity D. β1 agonistic activity in addition to α and β adrenergic blockade

Description : Labetalol has: A. More potent β adrenergic blocking than α blocking activity B. More potent α adrenergic blocking than β blocking activity C. Equal α and β adrenergic blocking activity D. β1 agonistic activity in addition to α and β adrenergic blockade

Last Answer : A. More potent β adrenergic blocking than α blocking activity

Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve

Description : Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve

Last Answer : C. Do not block any effect of injected adrenaline

Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve stimulation

Description : Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve stimulation

Last Answer : C. Do not block any effect of injected adrenaline

Metoclopramide blocks apomorphine induced vomiting, produces muscle dystonias and increases prolactin release indicates that it has: A. Anticholinergic action B. Antihistaminic action C. Anti 5-HT3 action D. Antidopaminergic action

Description : Metoclopramide blocks apomorphine induced vomiting, produces muscle dystonias and increases prolactin release indicates that it has: A. Anticholinergic action B. Antihistaminic action C. Anti 5-HT3 action D. Antidopaminergic action

Last Answer : D. Antidopaminergic action

The following action of chlorpromazine is not based on its antidopaminergic property: A. Antipsychotic B. Hyperprolactinemic C. Antiemetic D. Hypotensive

Description : The following action of chlorpromazine is not based on its antidopaminergic property: A. Antipsychotic B. Hyperprolactinemic C. Antiemetic D. Hypotensive

Last Answer : D. Hypotensive

Compared to other antipsychotic drugs, the distinctive feature of penfluridol is: A. Very long duration of action B. Weak dopamine D2 blocking activity C. Lack of extrapyramidal side effects D. Additional 5-HT2 receptor blocking activity

Description : Compared to other antipsychotic drugs, the distinctive feature of penfluridol is: A. Very long duration of action B. Weak dopamine D2 blocking activity C. Lack of extrapyramidal side effects D. Additional 5-HT2 receptor blocking activity

Last Answer : A. Very long duration of action

The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case

Description : The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case

Last Answer : D. They are the preferred drugs in advanced cases

Tyrosine kinase activity is present in (A) α-Adrenergic receptors (B) β-Adrenergic receptors (C) Cholinergic receptors (D) Insulin receptors

Description : Tyrosine kinase activity is present in (A) α-Adrenergic receptors (B) β-Adrenergic receptors (C) Cholinergic receptors (D) Insulin receptors

Last Answer : Answer : D

The following is true of propafenone except: A. It is a weak Na+ channel blocker B. It markedly delays recovery of myocardial Na+ channels C. It has additional β-adrenergic blocking property D. It slows anterograde as well as retrograde conduction in the WPW bypass tract

Description : The following is true of propafenone except: A. It is a weak Na+ channel blocker B. It markedly delays recovery of myocardial Na+ channels C. It has additional β-adrenergic blocking property D. It slows anterograde as well as retrograde conduction in the WPW bypass tract

Last Answer : A. It is a weak Na+ channel blocker

Ergotamine relieves migraine by: A. Blocking vascular α adrenergic receptors B. Blocking vascular 5-HT2 receptors C. Dilating cranial arterio-venous shunt channels D. Constricting cranial vessels and reducing perivascular neurogenic inflammation

Description : Ergotamine relieves migraine by: A. Blocking vascular α adrenergic receptors B. Blocking vascular 5-HT2 receptors C. Dilating cranial arterio-venous shunt channels D. Constricting cranial vessels and reducing perivascular neurogenic inflammation

Last Answer : D. Constricting cranial vessels and reducing perivascular neurogenic inflammation

Which of the following is a high potency antipsychotic drug having minimal sedative and autonomic effects and no propensity to cause weight gain: A. Chlorpromazine B. Triflupromazine C. Haloperidol D. Olanzapine

Description : Which of the following is a high potency antipsychotic drug having minimal sedative and autonomic effects and no propensity to cause weight gain: A. Chlorpromazine B. Triflupromazine C. Haloperidol D. Olanzapine

Last Answer : C. Haloperido

e primary mechanism by which general anaesthetics produce their action is: A. Affecting receptor operated ion channels in cerebral neurones B. Blocking voltage sensitive Na+ channels in neuronal membrane C. Depressing metabolic activity of cerebral neurones D. Blocking production of high energy phosphates in the brain

Description : e primary mechanism by which general anaesthetics produce their action is: A. Affecting receptor operated ion channels in cerebral neurones B. Blocking voltage sensitive Na+ channels in neuronal ... activity of cerebral neurones D. Blocking production of high energy phosphates in the brain

Last Answer : A. Affecting receptor operated ion channels in cerebral neurones

Choose the correct statement about long acting calcium channel blocking drugs as antihypertensives: A. They are the most effective drugs in suppressing hypertensive left ventricular hypertrophy B. They are as effective as diuretics or β blockers in reducing cardiovascular/total mortality C. They compromise quality of life more than β blockers D. They have no beneficial effect in hypertensive/diabetic nephropath

Description : Choose the correct statement about long acting calcium channel blocking drugs as antihypertensives: A. They are the most effective drugs in suppressing hypertensive left ventricular hypertrophy B. They ... more than β blockers D. They have no beneficial effect in hypertensive/diabetic nephropath

Last Answer : B. They are as effective as diuretics or β blockers in reducing cardiovascular/total mortality

Hydralazine is a directly acting vasodilator, but is not used alone as an antihypertensive because: A. By itself, it is a low efficacy antihypertensive B. Effective doses cause marked postural hypotension C. Tolerance to the antihypertensive action develops early due to counterregulatory mechanisms D. It primarily reduces systolic blood pressure with little effect on diastolic blood pressure

Description : Hydralazine is a directly acting vasodilator, but is not used alone as an antihypertensive because: A. By itself, it is a low efficacy antihypertensive B. Effective doses cause marked ... mechanisms D. It primarily reduces systolic blood pressure with little effect on diastolic blood pressure

Last Answer : C. Tolerance to the antihypertensive action develops early due to counterregulatory mechanisms

The most rapidly acting nondepolarizing neuromuscular blocking agent which can be used as an alternative to succinylcholine for tracheal intubation is: A. Rocuronium B. Pancuronium C. Doxacurium D. Pipecuronium

Description : The most rapidly acting nondepolarizing neuromuscular blocking agent which can be used as an alternative to succinylcholine for tracheal intubation is: A. Rocuronium B. Pancuronium C. Doxacurium D. Pipecuronium

Last Answer : A. Rocuronium

Which of the following is an idiosyncratic adverse drug reaction: A. Muscle dystonia caused by triflupromazine B. Insomnia after taking pentobarbitone C. Precipitation of asthma by morphine D. Gum hyperplasia caused by phenytoin

Description : Which of the following is an idiosyncratic adverse drug reaction: A. Muscle dystonia caused by triflupromazine B. Insomnia after taking pentobarbitone C. Precipitation of asthma by morphine D. Gum hyperplasia caused by phenytoin

Last Answer : B. Insomnia after taking pentobarbitone

The major limitation in the use of clozapine for treatment of schizophrenia is: A. Its potential to cause agranulocytosis B. Its inability to benefit negative symptoms of schizophrenia C. High incidence of extrapyramidal side effects

Description : The major limitation in the use of clozapine for treatment of schizophrenia is: A. Its potential to cause agranulocytosis B. Its inability to benefit negative symptoms of schizophrenia C. High incidence of extrapyramidal side effects

Last Answer : A. Its potential to cause agranulocytosis

The following is a selective 5-HT4 agonist: A. Buspirone B. Sumatriptan C. Cisapride D. Clozapine

Description : The following is a selective 5-HT4 agonist: A. Buspirone B. Sumatriptan C. Cisapride D. Clozapine

Last Answer : C. Cisapride

Beta adrenergic blockers lower intraocular tension by: A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors B. Constricting ciliary blood vessels C. Blocking adrenergic action on trabecular meshwork D. Reducing aqueous formation unrelated to beta adrenoceptor mediation

Description : Beta adrenergic blockers lower intraocular tension by: A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors B. Constricting ciliary blood vessels ... action on trabecular meshwork D. Reducing aqueous formation unrelated to beta adrenoceptor mediation

Last Answer : A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors

Beta adrenergic blockers lower intraocular tension by: A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors B. Constricting ciliary blood vessels C. Blocking adrenergic action on trabecular meshwork D. Reducing aqueous formation unrelated to beta adrenoceptor mediation

Description : Beta adrenergic blockers lower intraocular tension by: A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors B. Constricting ciliary blood vessels ... action on trabecular meshwork D. Reducing aqueous formation unrelated to beta adrenoceptor mediation

Last Answer : A. Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 adrenoceptors

Which of the following adverse effects of neuroleptic drugs is positively correlated to the antipsychotic potency of the different compounds: A. Sedation B. Extrapyramidal motor disturbances C. Postural hypotension D. Lowering of seizure threshold

Description : Which of the following adverse effects of neuroleptic drugs is positively correlated to the antipsychotic potency of the different compounds: A. Sedation B. Extrapyramidal motor disturbances C. Postural hypotension D. Lowering of seizure threshold

Last Answer : B. Extrapyramidal motor disturbances

The ‘neuroleptic syndrome’ produced by chlorpromazine like drugs is characterized by the following except: A. Emotional quietening B. Paucity of movements C. Ataxia D. Indifference to external cues

Description : The ‘neuroleptic syndrome’ produced by chlorpromazine like drugs is characterized by the following except: A. Emotional quietening B. Paucity of movements C. Ataxia D. Indifference to external cues

Last Answer : C. Ataxia

Glaucoma is treated by which of the following: w) androgenic drug x) androgenic blocking drug y) cholinergic drug z) anticholinergic drug

Description : Glaucoma is treated by which of the following: w) androgenic drug x) androgenic blocking drug y) cholinergic drug z) anticholinergic drug

Last Answer : ANSWER: Y -- CHOLINERGIC DRUG

The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are incompletely absorbed after oral administration C. They are devoid of CNS and ocular effects D. Dose to dose they are more potent than atropine

Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine

Last Answer : C. They are devoid of CNS and ocular effects

Improvement of memory in Alzheimer's disease is brought about by drugs which increase transmission in (A) cholinergic receptors (B) dopaminergic receptors (C) GABAergic receptors (D) adrenergic receptors

Description : Improvement of memory in Alzheimer's disease is brought about by drugs which increase transmission in (A) cholinergic receptors (B) dopaminergic receptors (C) GABAergic receptors (D) adrenergic receptors

Last Answer : (A) cholinergic receptors

Which antiemetic selectively blocks levodopa induced vomiting without blocking its antiparkinsonian action: A. Metoclopramide B. Cisapride C. Domperidone D. Ondansetron

Description : Which antiemetic selectively blocks levodopa induced vomiting without blocking its antiparkinsonian action: A. Metoclopramide B. Cisapride C. Domperidone D. Ondansetron

Last Answer : C. Domperidone

Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop of Henle. C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion

Description : Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop ... C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion

Last Answer : A. Preventing prostaglandin mediated intrarenal haemodynamic actions

Olanzapine has the following features except: A. It is an antipsychotic drug with weak D2 receptor blocking action B. It has potent 5-HT2 blocking and antimuscarinic actions C. It lowers seizure threshold D. It produces prominent extrapyramidal side effects

Description : Olanzapine has the following features except: A. It is an antipsychotic drug with weak D2 receptor blocking action B. It has potent 5-HT2 blocking and antimuscarinic actions C. It lowers seizure threshold D. It produces prominent extrapyramidal side effects

Last Answer : D. It produces prominent extrapyramidal side effect

Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Last Answer : A. They have potent antiovulatory action of their own

Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action

Last Answer : B. They produce many side effects

Rapid intravenous injection of clonidine causes rise in BP due to: A. Stimulation of vasomotor centre B. Release of noradrenaline from adrenergic nerve endings C. Agonistic action on vascular α2 adrenergic receptors D. Cardiac stimulation

Description : Rapid intravenous injection of clonidine causes rise in BP due to: A. Stimulation of vasomotor centre B. Release of noradrenaline from adrenergic nerve endings C. Agonistic action on vascular α2 adrenergic receptors D. Cardiac stimulation

Last Answer : C. Agonistic action on vascular α2 adrenergic receptors

6.12 The most prominent action of bromocriptine is: A. Dopamine D2 agonism B. Dopamine D2 antagonism C. Dopamine D1 antagonism D. α adrenergic antagonism

Description : 6.12 The most prominent action of bromocriptine is: A. Dopamine D2 agonism B. Dopamine D2 antagonism C. Dopamine D1 antagonism D. α adrenergic antagonism

Last Answer : A. Dopamine D2 agonism

The principal process which terminates the action of noradrenaline released from adrenergic nerve ending is: A. Degradation by MAO B. Methylation by COMT C. Axonal uptake D. Extraneuronal uptake

Description : The principal process which terminates the action of noradrenaline released from adrenergic nerve ending is: A. Degradation by MAO B. Methylation by COMT C. Axonal uptake D. Extraneuronal uptake

Last Answer : C. Axonal uptake

he following anthelmintic acts as a cholinergic agonist in the nematodes and causes spastic paralysis of the worms: A. Piperazine B. Pyrantel pamoate C. Mebendazole D. Thiabendazole

Description : he following anthelmintic acts as a cholinergic agonist in the nematodes and causes spastic paralysis of the worms: A. Piperazine B. Pyrantel pamoate C. Mebendazole D. Thiabendazole

Last Answer : B. Pyrantel pamoate

Choose the drug which blocks basal as well as stimulated gastric acid secretion without affecting cholinergic, histaminergic or gastrin receptors: A. Famotidine B. Loxatidine C. Omeprazole D. Pirenzepine

Description : Choose the drug which blocks basal as well as stimulated gastric acid secretion without affecting cholinergic, histaminergic or gastrin receptors: A. Famotidine B. Loxatidine C. Omeprazole D. Pirenzepine

Last Answer : C. Omeprazole

Histamine H2 blockers attenuate the gastric secretory response to acetylcholine and pentagastrin as well because: A. H2 blockers block gastric mucosal cholinergic and gastrin receptors as well B. H2 blockers inhibit the proton pump in gastric mucosa C. Acetylcholine and gastrin act partly by releasing histamine in gastric mucosa D. Histamine, acetylcholine and gastrin all act through the phospholipase C-IP3:DAG pathway in gastric mucosa

Description : Histamine H2 blockers attenuate the gastric secretory response to acetylcholine and pentagastrin as well because: A. H2 blockers block gastric mucosal cholinergic and gastrin receptors as well B. H2 ... acetylcholine and gastrin all act through the phospholipase C-IP3:DAG pathway in gastric mucosa

Last Answer : C. Acetylcholine and gastrin act partly by releasing histamine in gastric mucosa