The following type of vasodilator is not beneficial in CHF due to systolic dysfunction: A. Calcium channel blocker B. Angiotensin converting enzyme inhibitor C. Nitrate D. Hydralazine

The following type of vasodilator is not beneficial in
CHF due to systolic dysfunction:
A. Calcium channel blocker
B. Angiotensin converting enzyme inhibitor
C. Nitrate
D. Hydralazine
by

1 Answer

Answer :

A. Calcium channel blocker
by

Related questions

Hydralazine is a directly acting vasodilator, but is not used alone as an antihypertensive because: A. By itself, it is a low efficacy antihypertensive B. Effective doses cause marked postural hypotension C. Tolerance to the antihypertensive action develops early due to counterregulatory mechanisms D. It primarily reduces systolic blood pressure with little effect on diastolic blood pressure

Description : Hydralazine is a directly acting vasodilator, but is not used alone as an antihypertensive because: A. By itself, it is a low efficacy antihypertensive B. Effective doses cause marked ... mechanisms D. It primarily reduces systolic blood pressure with little effect on diastolic blood pressure

Last Answer : C. Tolerance to the antihypertensive action develops early due to counterregulatory mechanisms

Choose the correct statement about use of βadrenergic blockers in CHF: A. All β blockers are equally effective in CHF B. They are used as alternative to conventional therapy with ACE inhibitors ± digitalis/ diuretic C. They are most useful in mild to moderate cases with systolic dysfunction due to dilated cardiomyopathy D. They are indicated only in asymptomatic left ventricular dysfunction

Description : Choose the correct statement about use of βadrenergic blockers in CHF: A. All β blockers are equally effective in CHF B. They are used as alternative to conventional therapy with ... dysfunction due to dilated cardiomyopathy D. They are indicated only in asymptomatic left ventricular dysfunction

Last Answer : C. They are most useful in mild to moderate cases with systolic dysfunction due to dilated cardiomyopathy

Which vasodilator is most suitable for a patient of CHF who is symptomatic even at rest and has a central venous pressure of 25 mm Hg and cardiac index 1.8 L/min/m2 : A. Glyceryl trinitrate B. Enalapril C. Hydralazine D. Nifedipine

Description : Which vasodilator is most suitable for a patient of CHF who is symptomatic even at rest and has a central venous pressure of 25 mm Hg and cardiac index 1.8 L/min/m2 : A. Glyceryl trinitrate B. Enalapril C. Hydralazine D. Nifedipine

Last Answer : B. Enalapril

Vasodilators are used to treat: A. Acute heart failure attending myocardial infarction B. Chronic heart failure due to diastolic dysfunction C. Chronic heart failure due to both systolic as well as diastolic dysfunction D. All of the above

Description : Vasodilators are used to treat: A. Acute heart failure attending myocardial infarction B. Chronic heart failure due to diastolic dysfunction C. Chronic heart failure due to both systolic as well as diastolic dysfunction D. All of the above

Last Answer : D. All of the above

Angiotensin converting enzyme inhibitors are contraindicated in: A. High renin hypertensives B. Diabetics C. Congestive heart failure patients D. Pregnant women

Description : Angiotensin converting enzyme inhibitors are contraindicated in: A. High renin hypertensives B. Diabetics C. Congestive heart failure patients D. Pregnant women

Last Answer : D. Pregnant women

Clinically, the angiotensin antagonists share the following features of angiotensin converting enzyme inhibitors except: A. Antihypertensive efficacy B. Potential to reverse left ventricular hypertrophy C. Lack of effect on carbohydrate tolerance D. Potential to induce cough in susceptible individuals

Description : Clinically, the angiotensin antagonists share the following features of angiotensin converting enzyme inhibitors except: A. Antihypertensive efficacy B. Potential to reverse left ventricular hypertrophy ... of effect on carbohydrate tolerance D. Potential to induce cough in susceptible individuals

Last Answer : D. Potential to induce cough in susceptible individuals

Angiotensin converting enzyme inhibitors afford maximum protection against progression of heart failure when used: A. At the higher therapeutic dose range over long term B. At the maximum tolerated dose only till haemodynamic compensation is restored C. At low doses over long term D. At low doses along with diuretics/digoxi

Description : Angiotensin converting enzyme inhibitors afford maximum protection against progression of heart failure when used: A. At the higher therapeutic dose range over long term B. At the maximum tolerated dose only till ... restored C. At low doses over long term D. At low doses along with diuretics/digoxi

Last Answer : A. At the higher therapeutic dose range over long term

Angiotensin converting enzyme inhibitors reduce the following haemodynamic parameters in congestive heart failure except: A. Systemic vascular resistance B. Right atrial pressure C. Cardiac output D. Heart rate × pressure product

Description : Angiotensin converting enzyme inhibitors reduce the following haemodynamic parameters in congestive heart failure except: A. Systemic vascular resistance B. Right atrial pressure C. Cardiac output D. Heart rate × pressure product

Last Answer : C. Cardiac output

Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs C. They do not worsen blood lipid profile D. They do not impair work performance

Description : Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal ... . They do not worsen blood lipid profile D. They do not impair work performance

Last Answer : B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs

Potentiation of bradykinin appears to play a role in the following effects of angiotensin converting enzyme inhibitors except: A. Fall in BP in the short term B. Fall in BP in the long term C. Cough in susceptible individuals D. Angioedema in susceptible individuals

Description : Potentiation of bradykinin appears to play a role in the following effects of angiotensin converting enzyme inhibitors except: A. Fall in BP in the short term B. Fall in BP in the long term C. Cough in susceptible individuals D. Angioedema in susceptible individuals

Last Answer : B. Fall in BP in the long term

Under physiological conditions the rate limiting enzyme in the generation of angiotensin II is: A. Renin B. Angiotensin converting enzyme C. Aminopeptidase D. Angiotensinase

Description : Under physiological conditions the rate limiting enzyme in the generation of angiotensin II is: A. Renin B. Angiotensin converting enzyme C. Aminopeptidase D. Angiotensinase

Last Answer : A. Renin

Beneficial effects of β-adrenoceptor blockers in CHF include the following except: A. Antagonism of ventricular wall stress enhancing action of sympathetic overactivity B. Antagonism of vasoconstriction due to sympathetic overactivity C. Prevention of pathological remodeling of ventricular myocardium D. Prevention of dangerous cardiac arrhythmias

Description : Beneficial effects of β-adrenoceptor blockers in CHF include the following except: A. Antagonism of ventricular wall stress enhancing action of sympathetic overactivity B. Antagonism ... Prevention of pathological remodeling of ventricular myocardium D. Prevention of dangerous cardiac arrhythmias

Last Answer : B. Antagonism of vasoconstriction due to sympathetic overactivity

The following is true of β-adrenergic blocker therapy in CHF: A. They are added to conventional therapy after cardiac compensation is restored B. They are indicated only in severe (NYHA class IV) heart failure C. They are to be used only at low doses D. All of the above

Description : The following is true of β-adrenergic blocker therapy in CHF: A. They are added to conventional therapy after cardiac compensation is restored B. They are indicated only in severe (NYHA class IV) heart failure C. They are to be used only at low doses D. All of the above

Last Answer : A. They are added to conventional therapy after cardiac compensation is restored

A patient of CHF was treated with furosemide and digoxin. He became symptom-free and is stable for the last 3 months with resting heart rate 68/min in sinus rhythm but left ventricular ejection fraction is low. Which of the following lines of action is warranted: A. Stop above medication and start an ACE inhibitor B. Continue all medication as before C. Continue the diuretic but stop digoxin D. Continue digoxin but stop the diuretic

Description : A patient of CHF was treated with furosemide and digoxin. He became symptom-free and is stable for the last 3 months with resting heart rate 68/min in sinus rhythm but left ventricular ... medication as before C. Continue the diuretic but stop digoxin D. Continue digoxin but stop the diuretic

Last Answer : A. Stop above medication and start an ACE inhibitor

Choose the correct statement about trimetazidine: A. It is a novel calcium channel blocker B. It improves tissue perfusion by modifying rheological property of blood C. It is an antianginal drug which acts by nonhaemodynamic mechanisms D. Both 'A' and 'B' are correct

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Last Answer : C. It is an antianginal drug which acts by nonhaemodynamic mechanisms

The following calcium channel blocker should not be used in patients with ischaemic heart disease: A. Verapamil sustained release tablet B. Amlodipine tablet C. Nifedipine soft geletin capsule D. Nifedipine extended release tablet

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Last Answer : C. Nifedipine soft geletin capsule

The following calcium channel blocker is specifically indicated to counteract cerebral vasospasm and neurological sequelae following subarachnoid haemorrhage: A. Lacidipine B. Nimodipine C. Nicardipine D. Nitrendipine

Description : The following calcium channel blocker is specifically indicated to counteract cerebral vasospasm and neurological sequelae following subarachnoid haemorrhage: A. Lacidipine B. Nimodipine C. Nicardipine D. Nitrendipine

Last Answer : B. Nimodipine

The calcium channel blocker used for prophylaxis of migraine but not for angina pectoris is: A. Verapamil B. Diltiazem C. Flunarizine D. Amlodipine

Description : The calcium channel blocker used for prophylaxis of migraine but not for angina pectoris is: A. Verapamil B. Diltiazem C. Flunarizine D. Amlodipine

Last Answer : C. Flunarizine

Beneficial effect/effects of diuretics in CHF patients include the following: A. Symptomatic relief B. Regression of pathological changes C. Prolongation of life expectancy D. Both ‘A’ and ‘C’

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Last Answer : A. Symptomatic relief

The preferred class of drugs for long term treatment of severe anxiety disorder with intermittent panic attacks is: A. Phenothiazine (chlorpromazine like) B. Azapirone (buspirone like) C. β-blocker (propranolol like) D. Selective serotonin reuptake inhibitor (sertraline like)

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Last Answer : DD. Selective serotonin reuptake inhibitor (sertraline like)

Choose the correct statement about latanoprost: A. It is a PGF2α derivative used in glaucoma B. It is a selective α1 blocker used in benign hypertrophy of prostate C. It is a 5-α-reductase inhibitor used to reduce the size of enlarged prostate gland D. It is a PGE2 analogue used intravaginally for cervical priming

Description : Choose the correct statement about latanoprost: A. It is a PGF2α derivative used in glaucoma B. It is a selective α1 blocker used in benign hypertrophy of prostate C. It is a 5-α- ... reduce the size of enlarged prostate gland D. It is a PGE2 analogue used intravaginally for cervical priming

Last Answer : A. It is a PGF2α derivative used in glaucoma

Choose the correct statement about latanoprost: A. It is a PGF2α derivative used in glaucoma B. It is a selective α1 blocker used in benign hypertrophy of prostate C. It is a 5-α-reductase inhibitor used to reduce the size of enlarged prostate gland D. It is a PGE2 analogue used intravaginally for cervical priming

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Last Answer : A. It is a PGF2α derivative used in glaucoma

Which of the following is a specific inhibitor of the enzyme alcohol dehydrogenase and is useful in the treatment of methanol poisoning: A. Disulfiram B. Ethylene glycol C. Calcium leucovorin D. Fomepizole

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Last Answer : D. Fomepizole

Choose the correct statement about long acting calcium channel blocking drugs as antihypertensives: A. They are the most effective drugs in suppressing hypertensive left ventricular hypertrophy B. They are as effective as diuretics or β blockers in reducing cardiovascular/total mortality C. They compromise quality of life more than β blockers D. They have no beneficial effect in hypertensive/diabetic nephropath

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Last Answer : B. They are as effective as diuretics or β blockers in reducing cardiovascular/total mortality

Which of the following drugs is a potassium channel opener: A. Nicorandil B. Hydralazine C. Glibenclamide D. Amiloride

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Last Answer : D. Amiloride

Which of the following is a vasodilator drug used for hypertension that lacks a direct effect on autonomic receptors but may provoke anginal attacks? (a) Amyl nitrite (b) Hydralazine (c) Isosorbide mononitrate (d) Nifedipine (e) Nimodipine

Description : Which of the following is a vasodilator drug used for hypertension that lacks a direct effect on autonomic receptors but may provoke anginal attacks? (a) Amyl nitrite (b) Hydralazine (c) Isosorbide mononitrate (d) Nifedipine (e) Nimodipine

Last Answer : Ans: B

Which of the following statements about hypertension in diabetes patients is/are correct? A. Hypertension worsens the macrovascular disease of diabetes patients. B. Hypertension accelerates the progression of diabetic nephropathy. C. Hypertension is associated with sodium retention in diabetes patients. D. Angiotensin-converting enzyme (ACE) inhibitors should be used in all patients with chronic hyperglycemia, regardless of the presence of hypertension. E. Diuretics, as single-drug therapy, are not indicated in the treatment of hypertension in diabetes patients.

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Last Answer : C. Organic nitrates

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Last Answer : Answer : C

Which of the following statements most closely describes the current status of angiotensin converting enzyme inhibitors in congestive heart failure: A. They are the first choice drugs unless contraindicated B. They are used when diuretics alone fail C. They are a substitute for digitalis D. They are to be used as adjuncts only in resistant cases

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Last Answer : D. They are to be used as adjuncts only in resistant cases

The following is true of propafenone except: A. It is a weak Na+ channel blocker B. It markedly delays recovery of myocardial Na+ channels C. It has additional β-adrenergic blocking property D. It slows anterograde as well as retrograde conduction in the WPW bypass tract

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Last Answer : A. It is a weak Na+ channel blocker

Select the β-adrenergic blocker that has additional α1 blocking, vasodilator and antioxidant properties: A. Carvedilol B. Celiprolol C. Acebutolol D. Metoprolol

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Last Answer : A. Carvedilol

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Last Answer : A. Carvedilol

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Description : The following is a competitive type of enzyme inhibitor: A. Acetazolamide B. Disulfiram C. Physostigmine D. Theophylline

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Digitalis is most suitable for treatment of CHF when it is due to: A. Cor pulmonale B. Arterio-venous shunt C. Thiamine deficiency D. Long-standing uncontrolled hypertension

Description : Digitalis is most suitable for treatment of CHF when it is due to: A. Cor pulmonale B. Arterio-venous shunt C. Thiamine deficiency D. Long-standing uncontrolled hypertension

Last Answer : D. Long-standing uncontrolled hypertensio

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Last Answer : (c) Calcium ammonium nitrate

Tolerance does not develop to the vasodilator action of sodium nitroprusside while it develops to glyceryl trinitrate because: A. Intact sod. nitroprusside molecule acts like nitric oxide B. Enzymes which generate nitric oxide from nitroprusside are different C. Sod. nitroprusside has a long duration of action D. Sod. nitroprusside has additional K+ channel opening action

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Last Answer : B. Enzymes which generate nitric oxide from nitroprusside are different

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Last Answer : C. Sodium nitroprusside

The following vasodilator(s) act(s) by opening K+ channels in the vascular smooth muscle: A. Dipyridamole B. Minoxidil C. Diazoxide D. Both ‘B’ and ‘C’

Description : The following vasodilator(s) act(s) by opening K+ channels in the vascular smooth muscle: A. Dipyridamole B. Minoxidil C. Diazoxide D. Both ‘B’ and ‘C’

Last Answer : D. Both ‘B’ and ‘C

Select the drug which can markedly potentiate the vasodilator action of organic nitrates: A. Propranolol B. Fluoxetine C. Hydrochlorothiazide D. Sildenafil

Description : Select the drug which can markedly potentiate the vasodilator action of organic nitrates: A. Propranolol B. Fluoxetine C. Hydrochlorothiazide D. Sildenafil

Last Answer : D. Sildenafil

Isoxsuprine increases limb blood flow in normal individuals, but is of limited efficacy in Buerger’s disease, because in this disease: A. Vasodilator β adrenoceptors are deficient B. There is loss of sympathetic innervation C. Blood flow to the affected limb is reduced by organic obstruction D. The drug is not delivered to the affected site

Description : Isoxsuprine increases limb blood flow in normal individuals, but is of limited efficacy in Buerger's disease, because in this disease: A. Vasodilator β adrenoceptors are deficient B. There is loss ... affected limb is reduced by organic obstruction D. The drug is not delivered to the affected site

Last Answer : C. Blood flow to the affected limb is reduced by organic obstruction

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Description : Tolerance is generally not acquired to: A. Antisecretory action of atropine B. Sedative action of chlorpromazine C. Emetic action of levodopa D. Vasodilator action of nitrates

Last Answer : A. Antisecretory action of atropine

Isoxsuprine increases limb blood flow in normal individuals, but is of limited efficacy in Buerger’s disease, because in this disease: A. Vasodilator β adrenoceptors are deficient B. There is loss of sympathetic innervation C. Blood flow to the affected limb is reduced by organic obstruction D. The drug is not delivered to the affected site

Description : Isoxsuprine increases limb blood flow in normal individuals, but is of limited efficacy in Buerger's disease, because in this disease: A. Vasodilator β adrenoceptors are deficient B. There is loss ... affected limb is reduced by organic obstruction D. The drug is not delivered to the affected site

Last Answer : C. Blood flow to the affected limb is reduced by organic obstruction

Because of proven beneficial effects on “cardiac remodeling”, these agents are now indicated as first line therapy in CHF patients. Which of the following is representative of this group of drugs? (a) Hydrochlorothiazide (b) Enalapril (c) Furosemide (d) Carvedilol (e) Bumetanide

Description : Because of proven beneficial effects on “cardiac remodeling”, these agents are now indicated as first line therapy in CHF patients. Which of the following is representative of this group of drugs? (a) Hydrochlorothiazide (b) Enalapril (c) Furosemide (d) Carvedilol (e) Bumetanide

Last Answer : Ans: B

A semiconscious patient of haemorrhagic cerebral stroke has been brought to the emergency. His blood pressure is 240/120 mmHg. Select the procedure to lower his blood pressure as rapidly as possible: A. Sublingual nifedipine B. Intramuscular injection of hydralazine C. Intravenous infusion of sodium nitroprusside D. Intravenous injection of clonidin

Description : A semiconscious patient of haemorrhagic cerebral stroke has been brought to the emergency. His blood pressure is 240/120 mmHg. Select the procedure to lower his blood pressure as ... injection of hydralazine C. Intravenous infusion of sodium nitroprusside D. Intravenous injection of clonidin

Last Answer : C. Intravenous infusion of sodium nitroprussid

The following antihypertensive combination is irrational, and therefore should not be used: A. Nifedipine + hydralazine B. Amlodipine + atenolol C. Enalapril + clonidine D. Enalapril + hydrochlorothiazide

Description : The following antihypertensive combination is irrational, and therefore should not be used: A. Nifedipine + hydralazine B. Amlodipine + atenolol C. Enalapril + clonidine D. Enalapril + hydrochlorothiazide

Last Answer : TA. Nifedipine + hydralazine

The following antihypertensive drug tends to lower plasma renin activity: A. Clonidine B. Hydralazine C. Nifedipine D. Captopril

Description : The following antihypertensive drug tends to lower plasma renin activity: A. Clonidine B. Hydralazine C. Nifedipine D. Captopril

Last Answer : A. Clonidine

The following antihypertensive is used topically to treat alopacia areata: A. Hydralazine B. Prazosin C. Minoxidil D. Indapamide

Description : The following antihypertensive is used topically to treat alopacia areata: A. Hydralazine B. Prazosin C. Minoxidil D. Indapamide

Last Answer : C. Minoxidil