Description : Used alone the following antihypertensive drug tends to increase cardiac work and can precipitate angina: A. Clonidine B. Hydralazine C. Captopril D. Prazosin
Last Answer : B. Hydralazine
Description : Which of the following is a steroid 5α-reductase inhibitor that has been found useful in benign prostatic hypertrophy and male pattern baldness: A. Flutamide B. Finasteride C. Prazosin D. Minoxidil
Last Answer : B. Finasteride
Description : The following antihypertensive drug has been found to suppress certain manifestations of morphine withdrawal syndrome and to block postoperative pain when injected intrathecally: A. Prazosin B. Clonidine C. Reserpine D. Ketanserin
Last Answer : B. Clonidine
Description : The following antihypertensive drug has a favourable effect on plasma lipid profile: A. Prazosin B. Propranolol C. Hydrochlorothiazide D. Furosemide
Last Answer : A. Prazosin
Description : Which of the following feature(s) limit(s) the use of prazosin as a first line antihypertensive drug: A. Higher incidence of disturbing side effects B. Unfavourable metabolic effects C. Development of tolerance when used alone D. Both ‘A’ and ‘C’ are correct
Last Answer : D. Both ‘A’ and ‘C’ are correct
Description : Loss of taste sensation can be a side effect of the following antihypertensive drug: A. Clonidine B. Captopril C. Verapamil D. Prazosin
Last Answer : B. Captopril
Description : Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy
Last Answer : C. It does not concurrently enhance noradrenaline release
Description : The following antihypertensive combination is irrational, and therefore should not be used: A. Nifedipine + hydralazine B. Amlodipine + atenolol C. Enalapril + clonidine D. Enalapril + hydrochlorothiazide
Last Answer : TA. Nifedipine + hydralazine
Description : The following antihypertensive drug tends to lower plasma renin activity: A. Clonidine B. Hydralazine C. Nifedipine D. Captopril
Last Answer : A. Clonidine
Description : Hydralazine is a directly acting vasodilator, but is not used alone as an antihypertensive because: A. By itself, it is a low efficacy antihypertensive B. Effective doses cause marked ... mechanisms D. It primarily reduces systolic blood pressure with little effect on diastolic blood pressure
Last Answer : C. Tolerance to the antihypertensive action develops early due to counterregulatory mechanisms
Description : Features of clindamycin include the following: A. It is primarily active against aerobic gram negative bacilli B. It can be used topically to treat infected acne vulgaris C. It is not absorbed orally D. It is used to treat pseudomembranous enterocolitis
Last Answer : B. It can be used topically to treat infected acne vulgaris
Description : A friend has very severe hypertension and asks about a drug her doctor wishes to prescribe. Her physician has explained that this drug is associated with tachycardia and fluid retention (which may be marked ... has described? (a) Captopril (b) Guanethidine (c) Minoxidil (d) Prazosin (e) Propranolol
Last Answer : Ans: C
Description : A visitor from another city comes to your office complaining of incessant cough. He has diabetes and hypertension and has recently started taking a different antihypertensive medication. The most likely cause of his cough is (a) Enalapril (b) Losartan (c) Minoxidil (d) Propranolol (e) Verapamil
Last Answer : Ans: A
Description : Which of the following combinations of drugs, when used together, reduce both preload and afterload? (a) Nitroglycerin and isosorbide dinitrate (b) Hydralazine and isosorbide dinitrate (c) Captopril and methyldopa (d) Prazosin and angiotension II (e) Hydralazine and methyldopa
Last Answer : Ans: B
Description : Prazosin is an effective antihypertensive while nonselective a adrenergic blockers are not because (a) It is the only orally active a blocker (b) It improves plasma lipid profile (c) It does not concurrently enhance noradrenaline release (d) It improves urine flow in males with prostatic hypertrophy
Description : The following is not itself an efficacious diuretic, and is used only as an adjuvant/corrective to other diuretics: A. Acetazolamide B. Metolazone C. Spironolactone D. Indapamide
Last Answer : C. Spironolactone
Description : Which of the following has a ‘self limiting diuretic’ (action of the drug itself causing changes which limit further diuresis) action: A. Indapamide B. Spironolactone C. Xipamide D. Acetazolamide
Last Answer : D. Acetazolamide
Description : Select the diuretic which is orally active, efficacious in acidosis as well as alkalosis, causes diuresis even in renal failure and has additional carbonic anhydrase inhibitory action: A. Mannitol B. Benzthiazide C. Indapamide D. Furosemide
Last Answer : D. Furosemide
Description : Select the vasodilator that is administered only by slow intravenous infusion and dilates both resistance as well as capacitance vessels: A. Minoxidil B. Diazoxide C. Sodium nitroprusside D. Glyceryl trinitrate
Last Answer : C. Sodium nitroprusside
Description : The following vasodilator(s) act(s) by opening K+ channels in the vascular smooth muscle: A. Dipyridamole B. Minoxidil C. Diazoxide D. Both ‘B’ and ‘C’
Last Answer : D. Both ‘B’ and ‘C
Description : Select the drug which is a potassium channel opener as well as nitric oxide donor: A. Diazoxide B. Sodium nitroprusside C. Minoxidil D. Nicorandil
Last Answer : D. Nicorandil
Description : Choose the drug that can be used orally for intestinal amoebiasis, intravaginally for trichomonas vaginitis and topically for dermatophytosis: A. Quiniodochlor B. Furazolidone C. Ornidazole D. Hamycin
Last Answer : A. Quiniodochlor
Description : The distinctive feature of terbinafine is: A. It is highly effective in histoplasmosis B. It can be used topically as well as orally for dermatophytosis C. It inhibits Mucor and Aspergillus as well D. Applied intravaginally it cures both candida as well as trichomonas vaginitis
Last Answer : B. It can be used topically as well as orally for dermatophytosis
Description : Choose the azole antifungal drug which is used only topically: A. Ketoconazole B. Fluconazole C. Itraconazole D. Econazole
Last Answer : D. Econazole
Description : Select the correct statement about tibolone: A. It is an antiestrogen used for palliative treatment of carcinoma breast B. It is an estrogenic + progestational steroid used for hormone replacement ... for male pattern baldness D. It is a nonsteroidal estrogen used topically for senile vaginitis
Last Answer : B. It is an estrogenic + progestational steroid used for hormone replacement therapy in postmenopausal women
Description : Dorzolamide is a: A. Topically applied ocular carbonic anhydrase inhibitor B. Second generation sulfonylurea hypoglycaemic C. Topical sulfonamide antibacterial D. Luminal amoebicide
Last Answer : A. Topically applied ocular carbonic anhydrase inhibitor
Description : Which of the following is a prodrug of adrenaline used topically in glaucoma: A. Brimonidine B. Dipivefrine C. Phenylpropanolamine D. Dorzolamide
Last Answer : B. Dipivefrine
Description : Rebound hypertension on sudden stoppage of medication is most likely to occur with: A. Hydrochlorothiazide B. Prazosin C. Clonidine D. Lisinopri
Last Answer : C. Clonidine
Description : The following drug has been found to improve urine flow in elderly males with benign prostatic hypertrophy: A. Nifedipine B. Prazosin C. Disopyramide D. Imipramine
Last Answer : B. Prazosin
Description : In a patient of diabetes mellitus maintained on insulin therapy, administration of the following drug can vitiate glycaemia control: A. Prednisolone B. Prazosin C. Paracetamol D. Phenytoin
Last Answer : A. Prednisolone
Description : Select the drug which can improve urinary flow rate in benign prostatic hypertrophy without affecting prostate size: A. Amphetamine B. Prazosin C. Finasteride D. Goserelin
Description : The following is a selective α2 adrenoceptor antagonist: A. Prazosin B. Phentolamine C. Yohimbine D. Clonidine
Last Answer : C. Yohimbine
Description : The following is a selective α 2 adrenoceptor antagonist: A. Prazosin B. Phentolamine C. Yohimbine D. Clonidine
Description : A semiconscious patient of haemorrhagic cerebral stroke has been brought to the emergency. His blood pressure is 240/120 mmHg. Select the procedure to lower his blood pressure as ... injection of hydralazine C. Intravenous infusion of sodium nitroprusside D. Intravenous injection of clonidin
Last Answer : C. Intravenous infusion of sodium nitroprussid
Description : Long-term hydralazine therapy is likely to cause: A. Gynaecomastia B. Thrombocytopenia C. Haemolytic anaemia D. Lupus erythematosus
Last Answer : D. Lupus erythematosus
Description : Thiazide diuretics do not potentiate the antihypertensive action of one of the following drugs: A. Metoprolol B. Nifedipine C. Hydralazine D. Captopril
Last Answer : B. Nifedipine
Description : Which of the following drugs is a potassium channel opener: A. Nicorandil B. Hydralazine C. Glibenclamide D. Amiloride
Last Answer : D. Amiloride
Description : Which vasodilator is most suitable for a patient of CHF who is symptomatic even at rest and has a central venous pressure of 25 mm Hg and cardiac index 1.8 L/min/m2 : A. Glyceryl trinitrate B. Enalapril C. Hydralazine D. Nifedipine
Last Answer : B. Enalapril
Description : The following type of vasodilator is not beneficial in CHF due to systolic dysfunction: A. Calcium channel blocker B. Angiotensin converting enzyme inhibitor C. Nitrate D. Hydralazine
Last Answer : A. Calcium channel blocker
Description : Drug cumulation is the basis of organ toxicity of the following drug when used for prolonged periods: A. Prednisolone B. Chloroquine C. Aspirin D. Hydralazine
Last Answer : B. Chloroquine
Description : A drug which produces qualitatively different actions when administered through different routes is: A. Phenytoin sodium B. Hydralazine C. Magnesium sulfate D. Nitroglycerine
Last Answer : C. Magnesium sulfate
Description : A woman in the 28th week of pregnancy has developed pregnancy induced hypertension with a blood pressure reading of 150/100 mm Hg. Select the most appropriate antihypertensive drug for her: A. Furosemide B. Methyldopa C. Propranolol D. Captopril
Last Answer : B. Methyldopa
Description : Select the correct statement about combining antihypertensive drugs: A. Antihypertensive combinations should always be preferred over single drugs B. Combinations of antihypertensives with similar ... should be combined D. A diuretic must be included whenever antihypertensives are combined
Last Answer : C. Antihypertensives which act on different regulatory systems maintaining blood pressure should be combined
Description : The principles of antihypertensive drug usage enunciated in JNC VI and WHO-ISH guidelines include the following except: A. Therapy for grade I and II hypertension should be initiated with a single drug ... initially fails to lower BP, it should be replaced by a drug/combination from another class
Last Answer : C. All subjects with BP higher than 140/90 mmHg should be put on antihypertensive medication immediately
Description : Methyldopa differs from clonidine in the following respect: A. It is less likely to cause rebound hypertension on sudden discontinuation B. It does not reduce plasma renin activity C. It has a central as well as peripheral site of antihypertensive action D. It does not produce central side effect
Last Answer : A. It is less likely to cause rebound hypertension on sudden discontinuation
Description : n the treatment of hypertension the beta adrenergic blockers have the following advantage: A. They have minimal effect on work capacity, sleep quality and libido B. They do not cause ... high ceiling antihypertensive efficacy D. They can be used in combination with any other antihypertensive drug
Last Answer : B. They do not cause postural hypotension