The Na+-Cl– symport in the early distal convoluted
tubule of the kidney is inhibited by:
A. Thiazides
B. Metolazone
C. Xipamide
D. All of the above

1 Answer

Answer :

D. All of the above

Related questions

Description : The following diuretic acts on the luminal membrane of distal tubule and collecting ducts to inhibit electrogenic Na+ reabsorption so that K+ excretion is diminished and bicarbonate excretion is enhanced: A. Xipamide B. Isosorbide C. Triamterene D. Spironolactone

Last Answer : C. Triamterene

Description : Amiloride inhibits K+ excretion in the distal tubules and collecting ducts by blocking: A. Electrogenic K+ channels B. Electrogenic Na+ channels C. Nonelectrogenic Na+-Cl– symport D. H+K+ATPase

Last Answer : B. Electrogenic Na+ channels

Description : The Na+ retaining action of aldosterone is exerted on the: A. Proximal convoluted tubule B. Ascending limb of loop of Henle C. Cortical diluting segment D. Distal convoluted tubul

Last Answer : D. Distal convoluted tubule

Description : Secretion of K+ in the late distal tubule and collecting ducts of kidney depends on: A. Intracellular K+ content B. Unabsorbed Na+ load presented to the distal segment C. Aldosterone level D. All of the above

Last Answer : D. All of the above

Description : Select the diuretic which is similar in efficacy and pattern of electrolyte excretion to furosemide, but is 40 times more potent dose to dose: A. Piretanide B. Bumetanide C. Xipamide D. Metolazone

Last Answer : B. Bumetanide

Description : Assertion `:-` Antidiuretic hormone, increases the water permeability of distal convoluted tubule. Reason `:-` In the absence of ADH, water re-absorpt

Last Answer : Assertion `:-` Antidiuretic hormone, increases the water permeability of distal convoluted tubule. Reason ... . If both Assertion & Reason are false.

Description : Which of the following causes an increase in sodium reabsorption in the distal convoluted tubule

Last Answer : Which of the following causes an increase in sodium reabsorption in the distal convoluted tubule ... levels D. Decrease in antidiuretic hormone levels

Description : The final concentration of the fluid to produce a markedly hypertonic urine takes place in (a) Loop of Henle (b) Distal convoluted tubule (c) Collecting tubule (d) Both (b) and (c)

Last Answer : Ans:(c)

Description : The fluid reaching the distal convoluted tubule from the ascending limb of Henle's loop is (a) isotonic in respect of plasma (b) hypotonic in respect of plasma (c) hypertonic in respect of plasma (d) variable

Last Answer : Ans:(a)

Description : Anti-diuretic diuretic hormone (ADH) a. is synthesized by the posterior lobe of the pituitary gland b. is released by neurosecretion c. its secretion is increased by a low plasma osmolarity d. increases the permeability of the distal convoluted tubule

Last Answer : is released by neurosecretion

Description : Which of the following causes an increase in sodium reabsorption in the distal convoluted tubule? (a) Increase in aldosterone levels (b) Increase in antidiuretic hormone levels (c) Decrease in aldosterone levels (d) Decrease in antidiuretic hormone levels

Last Answer : (a) Increase in aldosterone levels

Description : Reabsorption of useful substances from glomerular filtrate occurs in (a) collecting tube (b) loop of Henle (c) proximal convoluted tubule (d) distal convoluted tubule.

Last Answer : (c) proximal convoluted tubule

Description : Which one of the following statements in regard to the excretion by the human kidneys is correct? (a) Descending limb of loop of Henle is impermeable to water. (b) Distal convoluted tubule is ... reabsorbed by the renal tubules. (d) Ascending limb of loop of Henle is impermeable to electrolytes.

Last Answer : (c) Nearly 99 per cent of the glomerular filtrate is reabsorbed by the renal tubules.

Description : Which one of the following correctly explains the function of a specific part of the human nephron? (a) Podocytes : create minute spaces (slit pores) for the filtration of blood into the ... blood capillaries (d) Afferent arteriole : carries the blood away from the glomerulus towards renal vein.

Last Answer : (a) Podocytes : create minute spaces (slit pores) for the filtration of blood into the Bowman’s capsule

Description : The maximum amount of electrolytes and water (70 – 80 percent) from the glomerular filtrate is reabsorbed in which part of the nephron? (a) Ascending limb of loop of Henle (b) Distal convoluted tubule (c) Proximal convoluted tubule (d) Descending limb of loop of Henle

Last Answer : (c) Proximal convoluted tubule

Description : The part of nephron involved in active reabsorption of sodium is (a) distal convoluted tubule (b) proximal convoluted tubule (c) Bowman’s capsule (d) descending limb of Henle’s loop.

Last Answer : (b) proximal convoluted tubule

Description : Which one of the four parts mentioned below does not constitute a part of single uriniferous tubule? (a) Distal convoluted tubule (b) Collecting duct (c) Bowman’s capsule (d) Loop of Henle

Last Answer : (b) Collecting duct

Description : Choose the correct statement about thiazide diuretics: A. They act in the proximal convoluted tubule B. They are uricosuric C. They augment corticomedullary osmotic gradient D. They induce diuresis in acidosis as well as alkalosis

Last Answer : D. They induce diuresis in acidosis as well as alkalosis

Description : Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop ... C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion

Last Answer : A. Preventing prostaglandin mediated intrarenal haemodynamic actions

Description : In the human kidney: a. renal plasma flow is normally 660 ml/minute b. blood flow in the cortex is greater than that in the medulla c. resorption of ions and water ... the distal convoluted tubules d. anti-diuretic hormone increases water resorption mainly in the distal convoluted tubules

Last Answer : blood flow in the cortex is greater than that in the medulla

Description : Thiazide diuretics enhance K+ elimination in urine primarily by: A. Inhibiting proximal tubular K+ reabsorption B. Inhibiting Na+ K+-2Cl- cotransport in the ascending limb of loop of Henle C ... in the distal tubular fluid to exchange with interstitial K+ D. Potentiating the action of aldosterone

Last Answer : C. Increasing the availability of Na+ in the distal tubular fluid to exchange with interstitial K

Description : The substance which is reabsorbed as well as excreted by the kidney tubule is (a) H+ (b) K+ (c) Na+ (d) Creatinine

Last Answer : Ans:(b)

Description : Which of the following has a ‘self limiting diuretic’ (action of the drug itself causing changes which limit further diuresis) action: A. Indapamide B. Spironolactone C. Xipamide D. Acetazolamide

Last Answer : D. Acetazolamide

Description : The most important reason for the thiazides being only moderately efficacious diuretics is: A. About 9/10th of glomerular filtrate is reabsorbed proximal to their site of action B. Compensatory ... these drugs C. They decrease glomerular filtration D. They have relatively flat dose response curve

Last Answer : A. About 9/10th of glomerular filtrate is reabsorbed proximal to their site of action

Description : Cyclic nucleotides exert the following action on salt transport across intestinal mucosal cells: A. Both cyclic AMP and cyclic GMP enhance Cland HCO3 - secretion B. Cyclic AMP enhances but cyclic GMP ... Cl- reabsorption D. Both cyclic AMP and cyclic GMP enhance Na+ and Cl- reabsorption

Last Answer : A. Both cyclic AMP and cyclic GMP enhance Cland HCO3 – secreti

Description : Furosemide acts by inhibiting the following in the renal tubular cell: A. Na+-K+-2Cl– cotransporter B. Na+-Cl– symporter C. Na+-H+ antiporter D. Na+ K+ ATPase

Last Answer : A. Na+-K+-2Cl– cotransporter

Description : Select the diuretic that can cause gynaecomastia, hirsutism and menstrual disturbance as a side effect on long-term use: A. Amiloride B. Spironolactone C. Metolazone D. Acetazolamide

Last Answer : B. Spironolactone

Description : The following is not itself an efficacious diuretic, and is used only as an adjuvant/corrective to other diuretics: A. Acetazolamide B. Metolazone C. Spironolactone D. Indapamide

Last Answer : C. Spironolactone

Description : The preferred diuretic for mobilizing edema fluid in CHF is: A. Hydrochlorothiazide B. Furosemide C. Metolazone D. Amiloride

Last Answer : B. Furosemide

Description : Assertion `:-` Proximal convoluted tubule is lined by brush-bordered cuboidal epithelium. Reason `:-` PCT is main site of selective reabsorption of us

Last Answer : Assertion `:-` Proximal convoluted tubule is lined by brush-bordered cuboidal epithelium. Reason `:-` ... D. If both Assertion & Reason are false.

Description : Removal of proximal convoluted tubule from the nephron will be result in

Last Answer : Removal of proximal convoluted tubule from the nephron will be result in A. More concentrated urine B. ... C. No urine formation D. More diluted urine

Description : Removal of proximal convoluted tubule from the nephron will be result in

Last Answer : Removal of proximal convoluted tubule from the nephron will be result in A. No urine formation B. ... D. No change in quality and quantity of urine

Description : In a normal nephron: a. the descending loop of Henle is impermeable to water b. anti-diuretic hormone (ADH) increases the permeability of collecting ducts to water c. all the filtered ... in the proximal tubule d. nearly all the filtered protein is reabsorbed in the proximal convoluted tubule

Last Answer : nearly all the filtered protein is reabsorbed in the proximal convoluted tubule

Description : Match the items given in column I with those in column II and select the correct option given below. Column I Column II (Function) (Part of excretory system) A. Ultrafiltration (i) Henle's loop B. Concentration (ii) Ureter of urine C. ... (ii) (iii) (c) (v) (iv) (i) (ii) (d) (v) (iv) (i) (iii)

Last Answer : (b) (iv) (i) (ii) (iii)

Description : Brush border is characteristic of (a) neck of nephron (b) collecting tube (c) proximal convoluted tubule (d) all of these.

Last Answer : (c) proximal convoluted tubule

Description : Removal of proximal convoluted tubule from the nephron will result in (a) no change in quality and quantity of urine (b) no urine formation (c) more diluted urine (d) more concentrated urine.

Last Answer : (c) more diluted urine

Description : Cuboidal epithelium with brush border of microvilli is found in (a) lining of intestine (b) ducts of salivary glands (c) proximal convoluted tubule of nephron (d) Eustachian tube

Last Answer : c) proximal convoluted tubule of nephron

Description : What structure is between the proximal and distal convoluted tubules?

Last Answer : Need answer

Description : Furosemide inhibits reabsorption of sodium and chloride in (A) Proximal convoluted tubules (B) Loop of Henle (C) Distal convoluted tubules (D) Collecting ducts

Last Answer : Answer : B

Description : Antidiuretic hormone (A) Is secreted by hypothalamus (B) Secretion is increased when osmolality of plasma decreases (C) Increases obligatory reabsorption of water (D) Acts on distal convoluted tubules and collecting ducts

Last Answer : Answer : D

Description : Obligatory reabsorption of water (A) Is about 50% of the total tubular reabsorption of water (B) Is increased by antidiuretic hormone (C) Occurs in distal convoluted tubules (D) Is secondary to reabsorption of solutes

Last Answer : Answer : D

Description : Aldosterone increases reabsorption of sodium in (A) Proximal convoluted tubules (B) Ascending limb of loop of Henle (C) Descending limb of loop of Henle (D) Distal convoluted tubules

Last Answer : Answer : D

Description : Proximal and distal convoluted tubules are parts of (a) seminiferous tubules (b) nephron (c) oviduct (d) vas deferens

Last Answer : (b) nephron

Description : Inhibition of carbonic anhydrase results in (a) Abolition of NaHCO3 reabsorption in proximal tubule (b) Enhanced of NaHCO3 reabsorption in proximal tubule (c) Enhanced NAHCO3 secretion in distal tubule (d) None of the above

Last Answer : Ans: A

Description : The primary site of action of thiazide diuretics is: A. Proximal tubule B. Ascending limb of loop of Henle C. Cortical diluting segment D. Collecting ducts

Last Answer : C. Cortical diluting segment

Description : Triamterene differs from spironolactone in that: A. It has greater natriuretic action B. Its K+ retaining action is not dependent on presence of aldosterone C. It acts from the luminal membrane side of the distal tubular cells D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

Description : True statements about aldosterone include: a. secretion is mainly under the control of adrenocorticotrophic (ACTH) hormone secretion b. increases hepatic gluconeogenesis c. its secretion is stimulated by angiotensin d. in the kidney, mainly acts on the proximal convoluted tubules

Last Answer : its secretion is stimulated by angiotensin

Description : Assertion `:-` Angiotensin II is a powerful vasconstrictor Reason `:-` Aldosterone causes reabsorption of `Na^(+)` and water from distal parts of the

Last Answer : Assertion `:-` Angiotensin II is a powerful vasconstrictor Reason `:-` Aldosterone causes reabsorption of ... D. If both Assertion & Reason are false.

Description : Mammalian cells are not inhibited by low concentrations of tetracyclines that inhibit sensitive microorganisms because: A. Host cells lack active transport mechanism for tetracyclines B. Host cells actively pump out ... host cells has low affinity for tetracyclines D. Both A' and C' are correct

Last Answer : D. Both ‘A’ and ‘C’ are correct