Select the diuretic that can cause gynaecomastia, hirsutism and menstrual disturbance as a side effect on long-term use: A. Amiloride B. Spironolactone C. Metolazone D. Acetazolamide

Select the diuretic that can cause gynaecomastia,
hirsutism and menstrual disturbance as a side effect
on long-term use:
A. Amiloride
B. Spironolactone
C. Metolazone
D. Acetazolamide
by

1 Answer

Answer :

B. Spironolactone
by

Related questions

The following is not itself an efficacious diuretic, and is used only as an adjuvant/corrective to other diuretics: A. Acetazolamide B. Metolazone C. Spironolactone D. Indapamide

Description : The following is not itself an efficacious diuretic, and is used only as an adjuvant/corrective to other diuretics: A. Acetazolamide B. Metolazone C. Spironolactone D. Indapamide

Last Answer : C. Spironolactone

A 55-year-old patient with severe posthepatitis cirrhosis is started on a diuretic for another condition. Two days later he is found in a coma. The drug most likely to cause coma in a patient with cirrhosis is (a) Acetazolamide (b) Amiloride (c) Furosemide (d) Hydrochlorothiazide (e) Spironolactone

Description : A 55-year-old patient with severe posthepatitis cirrhosis is started on a diuretic for another condition. Two days later he is found in a coma. The drug most likely to cause coma in a patient with cirrhosis is (a) Acetazolamide (b) Amiloride (c) Furosemide (d) Hydrochlorothiazide (e) Spironolactone

Last Answer : Ans: A

A patient of liver cirrhosis with ascitis was treated with hydrochlorothiazide 50 mg twice daily. He responded initially, but over a couple of months the diuretic action gradually diminished and ascitis again appeared. Select the measure to reinduce diuresis: A. Increase hydrochlorothiazide dose to 100 mg twice daily B. Add acetazolamide 250 mg twice daily C. Add spironolactone 50 mg thrice daily D. Substitute hydrochlorothiazide by spironolactone 50 mg 6 hourly

Description : A patient of liver cirrhosis with ascitis was treated with hydrochlorothiazide 50 mg twice daily. He responded initially, but over a couple of months the diuretic action gradually diminished ... Add spironolactone 50 mg thrice daily D. Substitute hydrochlorothiazide by spironolactone 50 mg 6 hourly

Last Answer : C. Add spironolactone 50 mg thrice daily

The preferred diuretic for mobilizing edema fluid in CHF is: A. Hydrochlorothiazide B. Furosemide C. Metolazone D. Amiloride

Description : The preferred diuretic for mobilizing edema fluid in CHF is: A. Hydrochlorothiazide B. Furosemide C. Metolazone D. Amiloride

Last Answer : B. Furosemide

At equinatriuretic doses which diuretic causes the maximum K+ loss: A. Furosemide B. Hydrochlorothiazide C. Acetazolamide D. Amiloride

Description : At equinatriuretic doses which diuretic causes the maximum K+ loss: A. Furosemide B. Hydrochlorothiazide C. Acetazolamide D. Amiloride

Last Answer : C. Acetazolamide

Which of the following has a ‘self limiting diuretic’ (action of the drug itself causing changes which limit further diuresis) action: A. Indapamide B. Spironolactone C. Xipamide D. Acetazolamide

Description : Which of the following has a ‘self limiting diuretic’ (action of the drug itself causing changes which limit further diuresis) action: A. Indapamide B. Spironolactone C. Xipamide D. Acetazolamide

Last Answer : D. Acetazolamide

The following diuretic abolishes the corticomedullary osmotic gradient in the kidney: A. Acetazolamide B. Furosemide C. Hydrochlorothiazide D. Spironolactone

Description : The following diuretic abolishes the corticomedullary osmotic gradient in the kidney: A. Acetazolamide B. Furosemide C. Hydrochlorothiazide D. Spironolactone

Last Answer : B. Furosemide

Select the diuretic which is similar in efficacy and pattern of electrolyte excretion to furosemide, but is 40 times more potent dose to dose: A. Piretanide B. Bumetanide C. Xipamide D. Metolazone

Description : Select the diuretic which is similar in efficacy and pattern of electrolyte excretion to furosemide, but is 40 times more potent dose to dose: A. Piretanide B. Bumetanide C. Xipamide D. Metolazone

Last Answer : B. Bumetanide

A diuretic which is an aldosterone antagonist is (A) Spironolactone (B) Ethacrynic acid (C) Acetazolamide (D) Chlorothiazide

Description : A diuretic which is an aldosterone antagonist is (A) Spironolactone (B) Ethacrynic acid (C) Acetazolamide (D) Chlorothiazide

Last Answer : Answer : A

Following potassium sparing diuretic is a mineralocorticoid receptor antagonist (a) Amiloride (b) Triamterene (c) Spironolactone (d) All of the above

Description : Following potassium sparing diuretic is a mineralocorticoid receptor antagonist (a) Amiloride (b) Triamterene (c) Spironolactone (d) All of the above

Last Answer : Ans: C

Following potassium sparing diuretic inhibits action of aldosterone (a) Amiloride (b) Triamterene (c) Spironolactone (d) All of the above

Description : Following potassium sparing diuretic inhibits action of aldosterone (a) Amiloride (b) Triamterene (c) Spironolactone (d) All of the above

Last Answer : Ans: C

Spironolactone can be usefully combined with the following diuretics except: A. Furosemide B. Amiloride C. Hydrochlorothiazide D. Chlorthalidone

Description : Spironolactone can be usefully combined with the following diuretics except: A. Furosemide B. Amiloride C. Hydrochlorothiazide D. Chlorthalidone

Last Answer : B. Amiloride

Adverse effects of ketoconazole include the following except: A. Gynaecomastia B. Oligozoospermia C. Kidney damage D. Menstrual irregularities

Description : Adverse effects of ketoconazole include the following except: A. Gynaecomastia B. Oligozoospermia C. Kidney damage D. Menstrual irregularities

Last Answer : C. Kidney damage

The most appropriate measure to overcome diminished responsiveness to furosemide after its longterm use is: A. Switching over to parenteral administration of furosemide B. Addition of a thiazide diuretic C. Addition of acetazolamide D. Potassium supplementation

Description : The most appropriate measure to overcome diminished responsiveness to furosemide after its longterm use is: A. Switching over to parenteral administration of furosemide B. Addition of a thiazide diuretic C. Addition of acetazolamide D. Potassium supplementation

Last Answer : B. Addition of a thiazide diuretic

The following diuretic acts on the luminal membrane of distal tubule and collecting ducts to inhibit electrogenic Na+ reabsorption so that K+ excretion is diminished and bicarbonate excretion is enhanced: A. Xipamide B. Isosorbide C. Triamterene D. Spironolactone

Description : The following diuretic acts on the luminal membrane of distal tubule and collecting ducts to inhibit electrogenic Na+ reabsorption so that K+ excretion is diminished and bicarbonate excretion is enhanced: A. Xipamide B. Isosorbide C. Triamterene D. Spironolactone

Last Answer : C. Triamterene

Long-term hydralazine therapy is likely to cause: A. Gynaecomastia B. Thrombocytopenia C. Haemolytic anaemia D. Lupus erythematosus

Description : Long-term hydralazine therapy is likely to cause: A. Gynaecomastia B. Thrombocytopenia C. Haemolytic anaemia D. Lupus erythematosus

Last Answer : D. Lupus erythematosus

Gynaecomastia can occur as a side effect of: A. Bromocriptine B. Cimetidine C. Famotidine D. Levodopa

Description : Gynaecomastia can occur as a side effect of: A. Bromocriptine B. Cimetidine C. Famotidine D. Levodopa

Last Answer : B. Cimetidine

Select the diuretic that is most effective in acute congestive glaucoma: A. Indapamide B. Amiloride C. Mannitol D. Furosemide

Description : Select the diuretic that is most effective in acute congestive glaucoma: A. Indapamide B. Amiloride C. Mannitol D. Furosemide

Last Answer : C. Mannitol

Select the diuretic that is most effective in acute congestive glaucoma: A. Indapamide B. Amiloride C. Mannitol D. Furosemide

Description : Select the diuretic that is most effective in acute congestive glaucoma: A. Indapamide B. Amiloride C. Mannitol D. Furosemide

Last Answer : C. Mannitol

The following adverse effect can occur even long after withdrawal of the offending drug: A. Paradoxical tachycardia B. Tardive dyskinesia C. Malignant hyperthermia D. Gynaecomastia

Description : The following adverse effect can occur even long after withdrawal of the offending drug: A. Paradoxical tachycardia B. Tardive dyskinesia C. Malignant hyperthermia D. Gynaecomastia

Last Answer : B. Tardive dyskinesia

A drug that is useful in glaucoma and high-altitude sickness is (a) Acetazolamide (b) Amiloride (c) Demeclocycline (d) Desmopressin (e) Ethacrynic acid

Description : A drug that is useful in glaucoma and high-altitude sickness is (a) Acetazolamide (b) Amiloride (c) Demeclocycline (d) Desmopressin (e) Ethacrynic acid

Last Answer : Ans: A

Which of the following diuretics would be most useful in a patient with cerebral edema? (a) Acetazolamide (b) Amiloride (c) Ethacrynic acid (d) Furosemide (e) Mannitol

Description : Which of the following diuretics would be most useful in a patient with cerebral edema? (a) Acetazolamide (b) Amiloride (c) Ethacrynic acid (d) Furosemide (e) Mannitol

Last Answer : Ans: E

Which of the following therapies would be most useful in the management of severe hypercalcemia? (a) Amiloride plus saline infusion (b) Furosemide plus saline infusion (c) Hydrochlorothiazide plus saline infusion (d) Mannitol plus saline infusion (e) Spironolactone plus saline infusion

Description : Which of the following therapies would be most useful in the management of severe hypercalcemia? (a) Amiloride plus saline infusion (b) Furosemide plus saline infusion (c) Hydrochlorothiazide plus saline infusion (d) Mannitol plus saline infusion (e) Spironolactone plus saline infusion

Last Answer : Ans: B

The following adverse effect(s) of phenytoin is/are related to high plasma drug concentration: A. Ataxia B. Hirsutism C. Gum hyperplasia D. All of the above

Description : The following adverse effect(s) of phenytoin is/are related to high plasma drug concentration: A. Ataxia B. Hirsutism C. Gum hyperplasia D. All of the above

Last Answer : A. Ataxia

Parenteral testosterone therapy in a boy can cause the following adverse effects except: A. Gynaecomastia B. Acne C. Cholestatic jaundice D. Precocious puberty

Description : Parenteral testosterone therapy in a boy can cause the following adverse effects except: A. Gynaecomastia B. Acne C. Cholestatic jaundice D. Precocious puberty

Last Answer : C. Cholestatic jaundice

16.10 Hyperprolactinemia can cause the following except: A. Amenorrhoea B. Gynaecomastia C. Multiple ovulation D. Depressed fertility

Description : 16.10 Hyperprolactinemia can cause the following except: A. Amenorrhoea B. Gynaecomastia C. Multiple ovulation D. Depressed fertility

Last Answer : . Multiple ovulation

Select the drug that can help restore cardiac performance as well as prolong survival in CHF patients: A. Spironolactone B. Furosemide C. Dobutamine D. Metoprolol

Description : Select the drug that can help restore cardiac performance as well as prolong survival in CHF patients: A. Spironolactone B. Furosemide C. Dobutamine D. Metoprolol

Last Answer : D. Metoprolol

Individual drugs of thiazide and related class of diuretics differ markedly from each other in the following respect? A. Diuretic efficacy B. Diuretic potency C. Side effects D. Propensity to cause hyperkalemia

Description : Individual drugs of thiazide and related class of diuretics differ markedly from each other in the following respect? A. Diuretic efficacy B. Diuretic potency C. Side effects D. Propensity to cause hyperkalemia

Last Answer : B. Diuretic potency

The following drug is used for short-term control of emergency heart failure, but not for long-term treatment of congestive heart failure: A. Digoxin B. Ramipril C. Dobutamine D. Spironolactone

Description : The following drug is used for short-term control of emergency heart failure, but not for long-term treatment of congestive heart failure: A. Digoxin B. Ramipril C. Dobutamine D. Spironolactone

Last Answer : C. Dobutamine

Triamterene differs from spironolactone in that: A. It has greater natriuretic action B. Its K+ retaining action is not dependent on presence of aldosterone C. It acts from the luminal membrane side of the distal tubular cells D. Both ‘B’ and ‘C’ are correct

Description : Triamterene differs from spironolactone in that: A. It has greater natriuretic action B. Its K+ retaining action is not dependent on presence of aldosterone C. It acts from the luminal membrane side of the distal tubular cells D. Both ‘B’ and ‘C’ are correct

Last Answer : D. Both ‘B’ and ‘C’ are correct

Amiloride has the following effect on urinary cation excretion: A. Decreases both K+ and H+ ion excretion B. Decreases K+ excretion but increases H+ ion excretion C. Increases K+ but decreases Na+ excretion D. Decreases both Na+ and K+ excretion

Description : Amiloride has the following effect on urinary cation excretion: A. Decreases both K+ and H+ ion excretion B. Decreases K+ excretion but increases H+ ion excretion C. Increases K+ but decreases Na+ excretion D. Decreases both Na+ and K+ excretion

Last Answer : A. Decreases both K+ and H+ ion excretion

Of the following diuretic medications, which conserves potassium? a) Spironolactone (Aldactone) Aldactone is known as a potassium-sparing diuretic. b) Furosemide (Lasix) Lasix causes loss of potassium from the body. c) Chlorothiazide (Diuril) Diuril causes mild hypokalemia. d) Chlorthalidone (Hygroton) Hygroton causes mild hypokalemia.

Description : Of the following diuretic medications, which conserves potassium? a) Spironolactone (Aldactone) Aldactone is known as a potassium-sparing diuretic. b) Furosemide (Lasix) Lasix causes loss of ... (Diuril) Diuril causes mild hypokalemia. d) Chlorthalidone (Hygroton) Hygroton causes mild hypokalemia.

Last Answer : a) Spironolactone (Aldactone) Aldactone is known as a potassium-sparing diuretic.

The Na+-Cl– symport in the early distal convoluted tubule of the kidney is inhibited by: A. Thiazides B. Metolazone C. Xipamide D. All of the above

Description : The Na+-Cl– symport in the early distal convoluted tubule of the kidney is inhibited by: A. Thiazides B. Metolazone C. Xipamide D. All of the above

Last Answer : D. All of the above

Select the diuretic which is orally active, efficacious in acidosis as well as alkalosis, causes diuresis even in renal failure and has additional carbonic anhydrase inhibitory action: A. Mannitol B. Benzthiazide C. Indapamide D. Furosemide

Description : Select the diuretic which is orally active, efficacious in acidosis as well as alkalosis, causes diuresis even in renal failure and has additional carbonic anhydrase inhibitory action: A. Mannitol B. Benzthiazide C. Indapamide D. Furosemide

Last Answer : D. Furosemide

Select the correct statement about combining antihypertensive drugs: A. Antihypertensive combinations should always be preferred over single drugs B. Combinations of antihypertensives with similar pattern of haemodynamic action are superior to those with dissimilar pattern C. Antihypertensives which act on different regulatory systems maintaining blood pressure should be combined D. A diuretic must be included whenever antihypertensives are combined

Description : Select the correct statement about combining antihypertensive drugs: A. Antihypertensive combinations should always be preferred over single drugs B. Combinations of antihypertensives with similar ... should be combined D. A diuretic must be included whenever antihypertensives are combined

Last Answer : C. Antihypertensives which act on different regulatory systems maintaining blood pressure should be combined

16.13 Gynaecomastia can be treated with: A. Chlorpromazine B. Cimetidine C. Bromocriptine D. Metoclopramide

Description : 16.13 Gynaecomastia can be treated with: A. Chlorpromazine B. Cimetidine C. Bromocriptine D. Metoclopramide

Last Answer : C. Bromocriptine

Which aminoglycoside antibiotic causes more hearing loss than vestibular disturbance as toxic effect: A. Streptomycin B. Gentamicin C. Kanamycin D. Sisomicin

Description : Which aminoglycoside antibiotic causes more hearing loss than vestibular disturbance as toxic effect: A. Streptomycin B. Gentamicin C. Kanamycin D. Sisomicin

Last Answer : C. Kanamycin

Combined tablets of thiazide or high ceiling diuretics with potassium chloride are not recommended because: A. Potassium absorbed while diuresis is occurring is largely excreted out B. Potassium administered concurrently diminishes the diuretic action C. Potassium chloride in tablet formulation is likely to cause gut ulceration D. Both ‘A’ and ‘C’ are correct

Description : Combined tablets of thiazide or high ceiling diuretics with potassium chloride are not recommended because: A. Potassium absorbed while diuresis is occurring is largely excreted out B. Potassium administered concurrently ... is likely to cause gut ulceration D. Both A' and C' are correct

Last Answer : D. Both ‘A’ and ‘C’ are correct

he current therapeutic indication of acetazolamide is: A. Congestive heart failure B. Renal insufficiency C. Cirrhosis of liver D. Glaucoma

Description : he current therapeutic indication of acetazolamide is: A. Congestive heart failure B. Renal insufficiency C. Cirrhosis of liver D. Glaucoma

Last Answer : D. Glaucoma

The following is a competitive type of enzyme inhibitor: A. Acetazolamide B. Disulfiram C. Physostigmine D. Theophylline

Description : The following is a competitive type of enzyme inhibitor: A. Acetazolamide B. Disulfiram C. Physostigmine D. Theophylline

Last Answer : C. Physostigmine

Choose the correct statement about amiloride: A. It antagonises the action of aldosterone B. It can be used to treat lithium induced diabetes insipidus C. It increases calcium loss in urine D. It is dose to dose less potent than triamterene

Description : Choose the correct statement about amiloride: A. It antagonises the action of aldosterone B. It can be used to treat lithium induced diabetes insipidus C. It increases calcium loss in urine D. It is dose to dose less potent than triamterene

Last Answer : B. It can be used to treat lithium induced diabetes insipidus

Amiloride inhibits K+ excretion in the distal tubules and collecting ducts by blocking: A. Electrogenic K+ channels B. Electrogenic Na+ channels C. Nonelectrogenic Na+-Cl– symport D. H+K+ATPase

Description : Amiloride inhibits K+ excretion in the distal tubules and collecting ducts by blocking: A. Electrogenic K+ channels B. Electrogenic Na+ channels C. Nonelectrogenic Na+-Cl– symport D. H+K+ATPase

Last Answer : B. Electrogenic Na+ channels

Aldosterone increases Na+ reabsorption and K+ excretion in the renal collecting duct cells by: A. Inducing synthesis of Na+K+ATPase B. Inducing synthesis of amiloride sensitive Na+ channels C. Translocating Na+ channels from cytosolic site to luminal membrane D. All of the above

Description : Aldosterone increases Na+ reabsorption and K+ excretion in the renal collecting duct cells by: A. Inducing synthesis of Na+K+ATPase B. Inducing synthesis of amiloride sensitive Na+ channels C. Translocating Na+ channels from cytosolic site to luminal membrane D. All of the above

Last Answer : D. All of the above

Which of the following drugs is a potassium channel opener: A. Nicorandil B. Hydralazine C. Glibenclamide D. Amiloride

Description : Which of the following drugs is a potassium channel opener: A. Nicorandil B. Hydralazine C. Glibenclamide D. Amiloride

Last Answer : D. Amiloride

The following apply to use of spironolactone in CHF except: A. It is indicated only in NYHA class III/IV cases as additional drug to conventional therapy B. It affords prognostic benefit in severe heart failure over and above that afforded by ACE inhibitors C. It helps overcome refractoriness to diuretics D. It affords rapid symptomatic relief

Description : The following apply to use of spironolactone in CHF except: A. It is indicated only in NYHA class III/IV cases as additional drug to conventional therapy B. It affords prognostic benefit in ... by ACE inhibitors C. It helps overcome refractoriness to diuretics D. It affords rapid symptomatic relief

Last Answer : D. It affords rapid symptomatic relief

The following drug can relieve symptoms of CHF but does not retard disease progression or prolong survival: A. Digoxin B. Carvedilol C. Spironolactone D. Ramipril

Description : The following drug can relieve symptoms of CHF but does not retard disease progression or prolong survival: A. Digoxin B. Carvedilol C. Spironolactone D. Ramipril

Last Answer : A. Digoxin

Concurrent administration of aspirin interacts unfavourably with the following drugs except: A. Furosemide B. Spironolactone C. Codeine D. Methotrexate

Description : Concurrent administration of aspirin interacts unfavourably with the following drugs except: A. Furosemide B. Spironolactone C. Codeine D. Methotrexate

Last Answer : C. Codeine

The most common and important undesirable effect of injectable contraceptive depot medroxyprogesterone acetate is: A. Nausea and vomiting B. Disruption of cyclic menstrual bleeding C. Venous thrombosis D. Hypertension

Description : The most common and important undesirable effect of injectable contraceptive depot medroxyprogesterone acetate is: A. Nausea and vomiting B. Disruption of cyclic menstrual bleeding C. Venous thrombosis D. Hypertension

Last Answer : B. Disruption of cyclic menstrual bleeding

75. At the start of thyroid replacement post-total thyroidectomy, the nurse must monitor for side effects. Which side effects would the nurse expect to assess? 1. Hypertension 2. Tremors 3. Hirsutism 4. Insomnia 5. Tachycardia 6. Hyperglycemia

Description : 75. At the start of thyroid replacement post-total thyroidectomy, the nurse must monitor for side effects. Which side effects would the nurse expect to assess? 1. Hypertension 2. Tremors 3. Hirsutism 4. Insomnia 5. Tachycardia 6. Hyperglycemia

Last Answer : A. 3, 4, 5, and 6

The characteristic toxicity of ethambutol is: A. Hepatitis B. Visual defects C. Vestibular disturbance D. Renal damage

Description : The characteristic toxicity of ethambutol is: A. Hepatitis B. Visual defects C. Vestibular disturbance D. Renal damage

Last Answer : B. Visual defects