Megaloblastic anaemia developing under the following condition is due entirely to folate deficiency not associated with vitamin B12 deficiency: A. Malnutrition B. Blind loop syndrome C. Phenytoin therapy D. Pregnancy

Megaloblastic anaemia developing under the following
condition is due entirely to folate deficiency not
associated with vitamin B12 deficiency:
A. Malnutrition
B. Blind loop syndrome
C. Phenytoin therapy
D. Pregnancy
by

1 Answer

Answer :

C. Phenytoin therapy
by

Related questions

A patient of megaloblastic anaemia was treated with oral folic acid 5 mg daily. After 2 weeks he reported back with cognitive deficit, sensory disturbance, depressed knee jerk, while blood picture and haemoglobin level were improved. What could be the most likely explanation: A. Folic acid was not adequately absorbed resulting in partial response B. Folate therapy has precipitated vitamin B12 deficiency in the neural tissue C. Folate therapy has unmasked pyridoxine deficiency D. Patient has folate reductase abnormality in the nervous system

Description : A patient of megaloblastic anaemia was treated with oral folic acid 5 mg daily. After 2 weeks he reported back with cognitive deficit, sensory disturbance, depressed knee jerk, while ... therapy has unmasked pyridoxine deficiency D. Patient has folate reductase abnormality in the nervous system

Last Answer : D. Patient has folate reductase abnormality in the nervous system

Megaloblastic anaemia occurs in: A. Vitamin B12 but not folic acid deficiency B. Folic acid but not Vitamin B12 deficiency C. Either Vitamin B12 or folic acid deficiency D. Only combined Vitamin B12 + folic acid deficiency

Description : Megaloblastic anaemia occurs in: A. Vitamin B12 but not folic acid deficiency B. Folic acid but not Vitamin B12 deficiency C. Either Vitamin B12 or folic acid deficiency D. Only combined Vitamin B12 + folic acid deficiency

Last Answer : C. Either Vitamin B12 or folic acid deficiency

Diphyllobothrium latum causes megaloblastic anaemia due to deficiency of vitamin B A. A12 B. B12 C. C D. D

Description : Diphyllobothrium latum causes megaloblastic anaemia due to deficiency of vitamin B A. A12 B. B12 C. C D. D

Last Answer : B12

The following is not a valid indication for parenteral iron therapy: A. Inadequate response to oral iron due to patient noncompliance B. Anaemia during pregnancy C. Severe anaemia associated with chronic bleeding D. Anaemia in a patient of active rheumatoid arthritis

Description : The following is not a valid indication for parenteral iron therapy: A. Inadequate response to oral iron due to patient noncompliance B. Anaemia during pregnancy C. Severe anaemia associated with chronic bleeding D. Anaemia in a patient of active rheumatoid arthritis

Last Answer : B. Anaemia during pregnancy

The metabolic reaction requiring vitamin B12 but not folate is: A. Conversion of malonic acid to succinic acid B. Conversion of homocysteine to methionine C. Conversion of serine to glycine D. Thymidylate synthesis

Description : The metabolic reaction requiring vitamin B12 but not folate is: A. Conversion of malonic acid to succinic acid B. Conversion of homocysteine to methionine C. Conversion of serine to glycine D. Thymidylate synthesis

Last Answer : A. Conversion of malonic acid to succinic acid

An epileptic woman controlled by phenytoin therapy conceives. Which of the following measures is most appropriate: A. Medical termination of pregnancy B. Withdraw phenytoin therapy C. Gradually reduce phenytoin dose to the lowest effective level D. Substitute phenytoin with a combination of carbamazepine and sodium valproate

Description : An epileptic woman controlled by phenytoin therapy conceives. Which of the following measures is most appropriate: A. Medical termination of pregnancy B. Withdraw phenytoin therapy C. ... lowest effective level D. Substitute phenytoin with a combination of carbamazepine and sodium valproate

Last Answer : C. Gradually reduce phenytoin dose to the lowest effective level

Sulfadoxine-pyrimethamine combination is used as clinical curative but is not recommended for prophylaxis of malaria because of: A. Risk of megaloblastic anaemia due to pyrimethamine B. Risk of severe dermatological reactions to sulfadoxine C. Need for daily administration of the d

Description : Sulfadoxine-pyrimethamine combination is used as clinical curative but is not recommended for prophylaxis of malaria because of: A. Risk of megaloblastic anaemia due to pyrimethamine B. Risk of severe dermatological reactions to sulfadoxine C. Need for daily administration of the d

Last Answer : B. Risk of severe dermatological reactions to sulfadoxine

A 60-year-old patient presented with anorexia, weakness, paresthesia and mental changes. His tongue was red, tendon reflexes were diminished, haemoglobin was 6 g% with large red cells and neutrophils had hypersegmented nuclei. Endoscopy revealed atrophic gastritis. Deficiency of which factor is likely to be responsible for his condition: A. Folic acid B. Vitamin B12 C. Pyridoxine D. Riboflavin

Description : A 60-year-old patient presented with anorexia, weakness, paresthesia and mental changes. His tongue was red, tendon reflexes were diminished, haemoglobin was 6 g% with large red cells and neutrophils had ... be responsible for his condition: A. Folic acid B. Vitamin B12 C. Pyridoxine D. Riboflavin

Last Answer : B. Vitamin B12

A deficiency of folate leads to (A) Megaloblastic anemia (B) Aplastic anemia (C) Pernicious anemia (D) Hypochromic microcytic anemia

Description : A deficiency of folate leads to (A) Megaloblastic anemia (B) Aplastic anemia (C) Pernicious anemia (D) Hypochromic microcytic anemia

Last Answer : Answer : A

A deficiency of folate leads to (A) Megaloblastic anemia (B) Aplastic anemia (C) Pernicious anemia (D) Hypochromic microcytic anemia

Description : A deficiency of folate leads to (A) Megaloblastic anemia (B) Aplastic anemia (C) Pernicious anemia (D) Hypochromic microcytic anemia

Last Answer : Answer : B

Folate deficiency causes (A) Microcytic anemia (B) Hemolytic anemia (C) Iron deficiency anemia (D) Megaloblastic anemia

Description : Folate deficiency causes (A) Microcytic anemia (B) Hemolytic anemia (C) Iron deficiency anemia (D) Megaloblastic anemia

Last Answer : Answer : D

Folate deficiency causes (A) Microcytic anemia (B) Hemolytic anemia (C) Iron deficiency anemia (D) Megaloblastic anemia

Description : Folate deficiency causes (A) Microcytic anemia (B) Hemolytic anemia (C) Iron deficiency anemia (D) Megaloblastic anemia

Last Answer : (D) Megaloblastic anemia

Choose the correct statement about iron therapy: A. Haemoglobin response to intramuscular iron is faster than with oral iron therapy B. Iron must be given orally except in pernicious anaemia C. Prophylactic iron therapy must be given during pregnancy D. Infants on breastfeeding do not require medicinal iron

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Last Answer : C. Prophylactic iron therapy must be given during pregnancy

Recombinant human erythropoietin is indicated for: A. Megaloblastic anaemia B. Haemolytic anaemia C. Anaemia in patients of thalassemia D. Anaemia in chronic renal failure patients

Description : Recombinant human erythropoietin is indicated for: A. Megaloblastic anaemia B. Haemolytic anaemia C. Anaemia in patients of thalassemia D. Anaemia in chronic renal failure patients

Last Answer : D. Anaemia in chronic renal failure patients

A patient of iron deficiency anaemia has been put on iron therapy. What should be the rate of rise in haemoglobin level of blood so that response is considered adequate: A. 0.05 – 0.1 g% per week B. 0.1 – 0.2 g% per week C. 0.5 – 1.0 g% per week D. More than 1.0 g% per week

Description : A patient of iron deficiency anaemia has been put on iron therapy. What should be the rate of rise in haemoglobin level of blood so that response is considered adequate: A. 0.05 – 0.1 g% per week B. 0.1 – 0.2 g% per week C. 0.5 – 1.0 g% per week D. More than 1.0 g% per week

Last Answer : C. 0.5 – 1.0 g% per week

The deficiency of Vitamin B12 leads to (A) Pernicious anaemia (B) Megablastic anaemia (C) Both (A) and (B) (D) None of these

Description : The deficiency of Vitamin B12 leads to (A) Pernicious anaemia (B) Megablastic anaemia (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

Pernicious anaemia in humans is caused by the deficiency of (a) Pyridoxine (Vitamin B6) (b) Cyanocobalamin (Vitamin B12) (c) Thiamine (Vitamin B1) (d) Pantothenic acid (Vitamin B5)

Description : Pernicious anaemia in humans is caused by the deficiency of (a) Pyridoxine (Vitamin B6) (b) Cyanocobalamin (Vitamin B12) (c) Thiamine (Vitamin B1) (d) Pantothenic acid (Vitamin B5)

Last Answer : Ans:(b)

Which vitamin deficiency causes the disease, Pernicious anaemia? (1) Vitamin B5 (2) Vitamin B12 (3) Vitamin B6 (4) Vitamin C

Description : Which vitamin deficiency causes the disease, Pernicious anaemia? (1) Vitamin B5 (2) Vitamin B12 (3) Vitamin B6 (4) Vitamin C

Last Answer : (2) Vitamin B12 Explanation: Pernicious anemia is one of many types of the larger family of megaloblastic anemias. It is caused by loss of gastric parietal cells which are responsible, in ... secretion of intrinsic factor, a protein essential for subsequent absorption of vitamin B12 in the ileum.

Which vitamin deficiency causes the disease, Pernicious anaemia ? (1) Vitamin B5 (2) Vitamin B12 (3) Vitamin B6 (4) Vitamin C

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Last Answer : Vitamin B12

Iron deficiency causes (A) Normocytic anaemia (B) Microcytic anaemia (C) Megaloblastic anaemia (D) Pernicious anaemia

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In a patient of diabetes mellitus maintained on insulin therapy, administration of the following drug can vitiate glycaemia control: A. Prednisolone B. Prazosin C. Paracetamol D. Phenytoin

Description : In a patient of diabetes mellitus maintained on insulin therapy, administration of the following drug can vitiate glycaemia control: A. Prednisolone B. Prazosin C. Paracetamol D. Phenytoin

Last Answer : A. Prednisolone

Cobalt forms an integral part of the vitamin: (A) B1 (B) B6 (C) B12 (D) Folate

Description : Cobalt forms an integral part of the vitamin: (A) B1 (B) B6 (C) B12 (D) Folate

Last Answer : Answer : C

A hypochromic microcytic anemia with increased iron stores in the bone marrow may be (A) Iron responsive (B) Pyridoxine responsive (C) Vitamin B12 responsive (D) Folate responsive

Description : A hypochromic microcytic anemia with increased iron stores in the bone marrow may be (A) Iron responsive (B) Pyridoxine responsive (C) Vitamin B12 responsive (D) Folate responsive

Last Answer : Answer : B

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Angular stomatitis is due to (A) Ariboflavinosis (B) Deficiency of Vitamin C (C) Deficiency of Vitamin B1 (D) Deficiency of folate

Description : Angular stomatitis is due to (A) Ariboflavinosis (B) Deficiency of Vitamin C (C) Deficiency of Vitamin B1 (D) Deficiency of folate

Last Answer : Answer : A

Angular stomatosis is due to (A) Ariboflavinoses (B) Deficiency of Vitamin C (C) Deficiency of Vitamin B1 (D) Deficiency of folate

Description : Angular stomatosis is due to (A) Ariboflavinoses (B) Deficiency of Vitamin C (C) Deficiency of Vitamin B1 (D) Deficiency of folate

Last Answer : Answer : B

The following drug can cause rickets in children by interfering with vitamin D action: A. Tetracycline B. Digoxin C. Phenytoin D. Ciprofloxacin

Description : The following drug can cause rickets in children by interfering with vitamin D action: A. Tetracycline B. Digoxin C. Phenytoin D. Ciprofloxacin

Last Answer : C. Phenytoin

Which of the following is true? Hypochromic anaemia is not due to iron deficiency except (A) Serum ‘Fe’ is high (B) Normal/low transferrin (C) Stainable iron in bone marrow (D) Iron therapy is affective

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A 19 year-old female is referred following a visit to the dentist where marked erosion of her teeth was noted. She was entirely asymptomatic and her only medication was the oral contraceptive pill. On examination her blood pressure was 110/70 mmHg and her body mass index was 21.5 kg/m2 (18 - 25). Investigations sodium 135 mmol/l potassium 2.1 mmol/l bicarbonate 42 mmol/l urea 2.6 mol/L corrected calcium 2.08 mmol/ alkaline phosphatase 201 iu/l (50-110) What is the most likely diagnosis? 1) Bulimia nervosa 2) Conn's syndrome 3) Laxative abuse 4) Pregnancy 5) Primary hypoparathyroidism

Description : A 19 year-old female is referred following a visit to the dentist where marked erosion of her teeth was noted. She was entirely asymptomatic and her only medication was the oral contraceptive pill ... ) Bulimia nervosa 2) Conn's syndrome 3) Laxative abuse 4) Pregnancy 5) Primary hypoparathyroidism

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A patient of chronic renal failure maintained on intermittent haemodialysis has anaemia not responding to iron therapy. Which of the following additional drug is indicated: A. Epoetin B. Cyanocobalamin C. Folic acid D. Pyridoxine

Description : A patient of chronic renal failure maintained on intermittent haemodialysis has anaemia not responding to iron therapy. Which of the following additional drug is indicated: A. Epoetin B. Cyanocobalamin C. Folic acid D. Pyridoxine

Last Answer : A. Epoetin

Long-term hydralazine therapy is likely to cause: A. Gynaecomastia B. Thrombocytopenia C. Haemolytic anaemia D. Lupus erythematosus

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Megaloblastic anemia is caused by the deficiency of (A) Folic acid (B) Vitamin B6 (C) Iron (D) Protein

Description : Megaloblastic anemia is caused by the deficiency of (A) Folic acid (B) Vitamin B6 (C) Iron (D) Protein

Last Answer : Answer : A

Megaloblastic anemia is caused by the deficiency of (A) Folic acid (B) Vitamin B6 (C) Iron (D) Protein

Description : Megaloblastic anemia is caused by the deficiency of (A) Folic acid (B) Vitamin B6 (C) Iron (D) Protein

Last Answer : Answer : A

Deficiency of Vitamin A causes (A) Xeropthalmia (B) Hypoprothrombinemia (C) Megaloblastic anemia (D) Pernicious anemia

Description : Deficiency of Vitamin A causes (A) Xeropthalmia (B) Hypoprothrombinemia (C) Megaloblastic anemia (D) Pernicious anemia

Last Answer : Answer : A

Deficiency of Vitamin A causes (A) Xeropthalmia (B) Hypoprothrombinemia (C) Megaloblastic anemia (D) Pernicious anemia

Description : Deficiency of Vitamin A causes (A) Xeropthalmia (B) Hypoprothrombinemia (C) Megaloblastic anemia (D) Pernicious anemia

Last Answer : (A) Xeropthalmia

A hypochromic microcytic anaemia which increases Fe, store in the bone marrow may be (A) Folic acid responsive (B) Vitamin B12 responsive (C) Pyridoxine responsive (D) Vitamin C responsive

Description : A hypochromic microcytic anaemia which increases Fe, store in the bone marrow may be (A) Folic acid responsive (B) Vitamin B12 responsive (C) Pyridoxine responsive (D) Vitamin C responsive

Last Answer : Answer : D

A hypochromic necrocytic anaemia with increase Fe stores in the bone marrow may be (A) Folic acid responsive (B) Vitamin B12 responsive (C) Pyridoxine responsive (D) Vitamin C responsive

Description : A hypochromic necrocytic anaemia with increase Fe stores in the bone marrow may be (A) Folic acid responsive (B) Vitamin B12 responsive (C) Pyridoxine responsive (D) Vitamin C responsive

Last Answer : Answer : C

Which one of the following pairs is not correctly matched? (a) Vitamin C - Scurvy (b) Vitamin B2 - Pellagra (c) Vitamin B12 - Pernicious anaemia (d) Vitamin B6 - Beri-beri

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Last Answer : (d) Vitamin B6 - Beri-beri

Which one of the following pairs is not correctly matched? (a) Vitamin B12 - Pernicious anaemia (b) Vitamin B6 - Convulsions (c) Vitamin B1 - Beri-beri (d) Vitamin B2 - Pellagra

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Last Answer : (d) Vitamin B2 - Pellagra

Select the oral iron preparation which does not impart metallic taste and has good oral tolerability despite high iron content but whose efficacy in treating iron deficiency anaemia has been questioned: A. Iron hydroxy polymaltose B. Ferrous succinate C. Ferrous fumarate D. Ferrous gluconate

Description : Select the oral iron preparation which does not impart metallic taste and has good oral tolerability despite high iron content but whose efficacy in treating iron deficiency anaemia has been questioned: A. Iron hydroxy polymaltose B. Ferrous succinate C. Ferrous fumarate D. Ferrous gluconate

Last Answer : A. Iron hydroxy polymaltose

Iron therapy is ineffective in which of the following conditions: (A) Chronic blood loss (B) Inadequate Fe intake (C) Hypochromic anaemia of pregnancy (D) Thalassaemia minor

Description : Iron therapy is ineffective in which of the following conditions: (A) Chronic blood loss (B) Inadequate Fe intake (C) Hypochromic anaemia of pregnancy (D) Thalassaemia minor

Last Answer : Answer : D

Following is the condition which might result due to deficiency of Calcium: C A. Hypercalcemia B. Anaemia C. Ricketts D. Cancer

Description : Following is the condition which might result due to deficiency of Calcium:  C A. Hypercalcemia B. Anaemia C. Ricketts D. Cancer

Last Answer : Ricketts

Isonicotinic acid hydrazide given in the treatment of tuberculosis may lead to a deficiency of (A) Vitamin A (B) Pyridoxin (C) Folate (D) Inositol

Description : Isonicotinic acid hydrazide given in the treatment of tuberculosis may lead to a deficiency of (A) Vitamin A (B) Pyridoxin (C) Folate (D) Inositol

Last Answer : Answer : B

Isonicotinic acid hydrazide given in the treatment of tuberculosis may lead to a deficiency of (A) Vitamin A (B) Pyridoxin (C) Folate (D) Inositol

Description : Isonicotinic acid hydrazide given in the treatment of tuberculosis may lead to a deficiency of (A) Vitamin A (B) Pyridoxin (C) Folate (D) Inositol

Last Answer : Answer : D

Hydroxocobalamin differs from cyanocobalamin in that: A. It is more protein bound and better retained B. It is beneficial in tobacco amblyopia C. It benefits haematological but not neurological manifestations of vit B12 deficiency D. Both ‘A’ and ‘B’ are correct

Description : Hydroxocobalamin differs from cyanocobalamin in that: A. It is more protein bound and better retained B. It is beneficial in tobacco amblyopia C. It benefits haematological but not neurological manifestations of vit B12 deficiency D. Both ‘A’ and ‘B’ are correct

Last Answer : C. It benefits haematological but not neurological manifestations of vit B12 deficiency

Features of methylcobalamin include the following: A. It is an active coenzyme form of vit B12 B. It is required for the synthesis of S-adenosyl methionine C. It is specifically indicated for correcting neurological defects of vit B12 deficiency D. All of the above

Description : Features of methylcobalamin include the following: A. It is an active coenzyme form of vit B12 B. It is required for the synthesis of S-adenosyl methionine C. It is specifically indicated for correcting neurological defects of vit B12 deficiency D. All of the above

Last Answer : D. All of the above

Gastyrectomy leads to megaloblastic anaemia within a few (A) Days (B) Weeks (C) Months (D) Years

Description : Gastyrectomy leads to megaloblastic anaemia within a few (A) Days (B) Weeks (C) Months (D) Years

Last Answer : Answer : D

Lesch-Nyhan syndrome, the sex linked, recessive absence of HGPRTase, may lead to (A) Compulsive self destructive behaviour with elevated levels of urate in serum (B) Hypouricemia due to liver damage (C) Failure to thrive and megaloblastic anemia (D) Protein intolerance and hepatic encephalopathy

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Last Answer : Answer : A

Disease caused due to deficiency of vitamin B12

Description : Disease caused due to deficiency of vitamin B12

Last Answer : Ans. Pernicious anaemia

The disease Beni Beni is caused due to the deficiency of which of the following? (1) Vitamin B2 (2) Vitamin B1 (3) Vitamin B12 (4) Vitamin E

Description : The disease Beni Beni is caused due to the deficiency of which of the following? (1) Vitamin B2 (2) Vitamin B1 (3) Vitamin B12 (4) Vitamin E

Last Answer : (2) Vitamin B1 Explanation: Beriberi is a disease caused by a vitamin B1 (thiamine) deficiency. There are two types of the disease: wet beriberi and dry beriberi. Wet beriberi affects the heart ... -beri damages the nerves and can lead to a loss of muscle strength and eventually, muscle paralysis.