Human have probably been using mind – affecting drugs since time immemorial. The root cause of addiction of man to drugs, smoking and drinking has been due to his inability to make mental adjustments with stresses and strains, drudgery and extreme misery in daily life. As a temporary measure, to combat these adverse situations and to have a certain degree of mental relaxation, humans have been making an extensive use of stimulants, depressants and hallucinogens. Stimulants generally speed up body process, and depressants slow them. Hallucinogens can alter a person’s thoughts, feelings, and perception. In preventing drug abuse, the role of parents could be: (i) Communicate openly with the children, listen to their problems patiently and teach them how to handle the problems. (ii) Take interest in children’s activities and their friends circle. (iii) Set an example for children by not taking drugs or alcohol. (iv) Keep track of prescribed drugs in home. (v) Learn as much as possible about drugs.