The most probable mechanism of action of imidazole antifungal drugs is: A. They bind to ergosterol in fungal cell membrane and make it leaky B. They interfere with ergosterol synthesis by fungi C. They interfere with fungal mitosis D. They block oxidative phosphorylation in fungi

The most probable mechanism of action of imidazole
antifungal drugs is:
A. They bind to ergosterol in fungal cell membrane and make it leaky
B. They interfere with ergosterol synthesis by
fungi
C. They interfere with fungal mitosis
D. They block oxidative phosphorylation in
fungi
by

1 Answer

Answer :

B. They interfere with ergosterol synthesis by
fungi
by

Related questions

By which of the following means antifungal chemotherapeutic agents may affect fungi? A- Interfere with nuclear division by preventing the aggregation of microtubules needed for mitosis B- Interfere with normal nucleic acid synthesisInterfere with ergosterol biosynthesis and thus alter the structure of the cytoplasmic C- membrane as well as the function of several membrane-bound enzymes like thoseinvolved in nutrient transport and chitin synthesis D- all of these

Description : By which of the following means antifungal chemotherapeutic agents may affect fungi? A- Interfere with nuclear division by preventing the aggregation of microtubules needed for mitosis B- ... membrane-bound enzymes like thoseinvolved in nutrient transport and chitin synthesis D- all of these

Last Answer : all of these

The most important mechanism by which tetracycline antibiotics exert antimicrobial action is: A. They chelate Ca2+ ions and alter permeability of bacterial cell membrane B. They bind to 30S ribosomes and inhibit bacterial protein synthesis C. They bind to 50S ribosomes and interfere with translocation of the growing peptide chain in the bacteria D. They interfere with DNA mediated RNA synthesis in bacteria

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Last Answer : B. They bind to 30S ribosomes and inhibit bacterial protein synthesis

The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is (a) They chelate Ca2+ ions and alter permeability of bacterial cell membrane (b) They bind to 30S ribosomes and inhibit bacterial protein synthesis (c) They bind to 50S ribosomes and interfere with translocation of the growing peptide chain in the bacteria (d) They interfere with DNA mediated RNA synthesis in bacteria

Description : The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is (a) They chelate Ca2+ ions and alter permeability of bacterial cell membrane (b) They bind to 30S ribosomes ... peptide chain in the bacteria (d) They interfere with DNA mediated RNA synthesis in bacteria

Last Answer : Ans: B

The polyene antibiotics act by: A. Inhibiting fungal cytochrome P450 enzyme B. Binding to ergosterol and creating micropores in fungal cell membrane C. Inhibiting fungal DNA synthesis D. Disorienting microtubules in fungal cells

Description : The polyene antibiotics act by: A. Inhibiting fungal cytochrome P450 enzyme B. Binding to ergosterol and creating micropores in fungal cell membrane C. Inhibiting fungal DNA synthesis D. Disorienting microtubules in fungal cells

Last Answer : B. Binding to ergosterol and creating micropores in fungal cell membrane

All of the following statements about the enzymic complex that carries out the synthesis of ATP during oxidative phosphorylation are correct except (A) It is located on the matrix side of the inner mitochondrial membrane (B) It is inhibited by oligomycin (C) It can exhibit ATPase activity (D) It can bind molecular O2

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Last Answer : D

Leishmania donovani is susceptible to certain antifungal drugs because both fungi and Leishmania: A. Utilise purine salvage pathway B. Utilise similar glycolytic mechanisms C. Have similar topoisomerase II enzyme D. Have ergosterol in their cell membranes

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Last Answer : D. Have ergosterol in their cell membranes

Aminoglycoside antibiotics exert the following action(s) on sensitive bacteria: A. Induce synthesis of defective proteins B. Make bacterial cell membrane more leaky C. Augment their own carrier mediated entry into the bacteria D. All of the above

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The imidazole drugs are of value for treating a. Viral diseases. b. Protozoal diseases and bacterial diseases. c. Bacterial diseases. d. Fungal diseases.

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Last Answer : d. Fungal diseases

Bactericidal action of aminoglycoside antibiotics is due to: A. Inhibition of bacterial protein synthesis B. Alteration of bacterial cell membrane permeability C. Damage to bacterial cell wall D. Inhibition of bacterial oxidative metabolism

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The organophosphates produce irreversible inhibition of cholinesterase because: A. They bind to an allosteric site of the enzyme resulting in unfavourable conformation of esteratic site to bind acetylcholine B. Regeneration time of the phosphorylated enzyme is longer than the turnover time of the enzyme molecules C. Phosphorylation results in rapid degradation of enzyme molecules D. They are neither metabolized nor excreted from the body

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Last Answer : C. Loss of intracellular microtubules and inhibition of glucose uptake in the worm

The most probable mechanism of anticonvulsant action of phenytoin is: A. Facilitation of GABAergic inhibitory transmission B. Hyperpolarization of neurones C. Interaction with Ca2+ channels to promote Ca2+ influx D. Prolongation of voltage sensitive neuronal Na+ channel inactivation

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ntithyroid drugs exert the following action: A. Inhibit thyroxine synthesis B. Block the action of thyroxine on pituitary C. Block the action of TSH on thyroid D. Block the action of thyroxine on peripheral tissues

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Last Answer : A. Inhibit thyroxine synthesis

Antithyroid drugs exert the following action: A. Inhibit thyroxine synthesis B. Block the action of thyroxine on pituitary C. Block the action of TSH on thyroid D. Block the action of thyroxine on peripheral tissues

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The following are topical antifungal drugs except: A. Ciclopirox olamine B. Tolnaftate C. Crotamiton D. Terbinafine

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Last Answer : C. Crotamiton

An uncoupler of oxidative phosphorylation such as dinitrophenol (A) Inhibits electron transport and ATP synthesis (B) Allow electron transport to proceed without ATP synthesis (C) Inhibits electron transport without impairment of ATP synthesis (D) Specially inhibits cytochrome b

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Last Answer : B

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The following statements are true of oral anticoagulants except: A. They interfere with an early step in the synthesis of clotting factors B. Irrespective of the dose administered, their anticoagulant effect has a latency of onset of 1-3 days C. Their dose is adjusted by repeated measurement of prothrombin time D. They are contraindicated during pregnancy

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Last Answer : (a) reversible protein phosphorylation as a biological regulation mechanism

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The primary action by which entacapone and tolcapone enhance the therapeutic effect of levodopa-carbidopa in parkinsonism is: A. Inhibition of levodopa methylation in the liver B. Inhibition of dopamine methylation in the brain C. Inhibition of oxidative deamination of dopamine in the brain D. Facilitation of active transport of levodopa across brain capillaries

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Last Answer : A. Inhibition of levodopa methylation in the liver

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Which antifungal agent is effective in both dermatophytosis as well as systemic mycosis: A. Amphotericin B B. Griseofulvin C. Clotrimazole D. Ketoconazole

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Why is oxygen needed for oxidative phosphorylation? -Biology

Description : Why is oxygen needed for oxidative phosphorylation? -Biology

Last Answer : answer:

What is oxidative phosphorylation? -Biology

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Last Answer : answer:

Site of Krebs cycle and oxidative phosphorylation. -Biology

Description : Site of Krebs cycle and oxidative phosphorylation. -Biology

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An oxidative phosphorylation is the formation of

Description : An oxidative phosphorylation is the formation of

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The chemical inhibiting oxidative phosphorylation, Adependent on the transport of adenine nucleotides across the inner mitochondrial membrane is (A) Oligomycin (B) Atractyloside (C) Dinitrophenol (D) Pentachlorophenol

Description : The chemical inhibiting oxidative phosphorylation, Adependent on the transport of adenine nucleotides across the inner mitochondrial membrane is (A) Oligomycin (B) Atractyloside (C) Dinitrophenol (D) Pentachlorophenol

Last Answer : Answer : B

An uncoupler of oxidative phosphorylation is (A) Carboxin (B) Atractyloside (C) Amobarbital (D) Dinitrocresol

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Last Answer : Answer : D

The number of ATP produced in the oxidation of 1 molecule of NADPH in oxidative phosphorylation is (A) Zero (B) 2 (C) 3 (D) 4

Description : The number of ATP produced in the oxidation of 1 molecule of NADPH in oxidative phosphorylation is (A) Zero (B) 2 (C) 3 (D) 4

Last Answer : Answer : A

Chemiosmotic theory for oxidative phosphorylation has been proposed by (A) Chance and Williams (B) Pauling and Corey (C) S. Waugh (D) P. Mitchell

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Last Answer : Answer : D

In non shivering thermogenesis (A) Glucose is oxidized to lactate (B) Fatty acids uncouple oxidative phosphorylation (C) Ethanol is formed (D) ATP is burned for heat production

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Tissues form lactic acid from glucose. This phenomenon is termed as (A) Aerobic glycolysis (B) Oxidation (C) Oxidative phosphorylation (D) Anaerobic glycolysis

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Oxidative phosphorylation is production of (a) ATP in photosynthesis (b) NADPH in photosynthesis (c) ATP in respiration (d) NADH in respiration

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Last Answer : (c) ATP in respiration

Oxidative phosphorylation is (a) formation of ATP by transfer of phosphate group from a substrate to ADP (b) oxidation of phosphate group in ATP (c) addition of phosphate group to ATP (d) formation of ATP by energy released from electrons removed during substrate oxidation.

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Which of these statements is incorrect? (a) Enzymes of TCA cycle are present in mitochondrial matrix. (b) Glycolysis occurs in cytosol. (c) Glycolysis operates as long as it is supplied with NAD that can pick up hydrogen atoms. (d) Oxidative phosphorylation takes place in outer mitochondrial membrane

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The chemiosmotic coupling hypothesis of oxidative phosphorylation proposes that adenosine triphosphate (ATP) is formed because (a) a proton gradient forms across the inner membrane(b) there is a change in the permeability of the inner mitochondrial membrane toward adenosine diphosphate (ADP) (c) high energy bonds are formed in mitochondrial proteins (d) ADP is pumped out of the matrix into the intermembrane space.

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Read the following four statements (A – D). (A) Both photophosphorylation and oxidative phosphorylation involve uphill transport of protons across the membrane. (B) In dicot stems, a new cambium originates from cells of pericycle at the time of secondary growth. (C) Stamens in flowers of Gloriosa and Petunia are polyandrous.(D) Symbiotic nitrogen fixers occur in free-living state also in soil.

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Last Answer : (A) Both photophosphorylation and oxidative phosphorylation involve uphill transport of protons across the membrane.