Description : The only azole antifungal drug which has some activity against moulds like Aspergillus is: A. Itraconazole B. Fluconazole C. Miconazole D. Ketoconazole
Last Answer : A. Itraconazole
Description : Fluconazole differs from ketoconazole in that: A. It is not active by the oral route B. It is a more potent inhibitor of drug metabolism C. It is not effective in cryptococcal meningitis D. It is unlikely to produce anti-androgenic side effects
Last Answer : D. It is unlikely to produce anti-androgenic side effects
Description : Select the antifungal drug which is administered only by the oral route: A. Amphotericin B B. Ketoconazole C. Griseofulvin D. Tolnaftate
Last Answer : C. Griseofulvin
Description : The following drugs are effective in systemic mycosis except: A. Terbinafine B. Itraconazole C. Ketoconazole D. Fluconazol
Last Answer : A. Terbinafine
Description : The following is applicable to itraconazole except: A. It has largely replaced ketoconazole for treatment of systemic mycosis B. It does not inhibit human steroid hormone synthesis C. It is ... the treatment of fungal meningitis D. It can interact with terfenadine to produce ventricular arrhythmias
Last Answer : C. It is preferred for the treatment of fungal meningitis
Description : Fluconazole offers the following advantage(s) over ketoconazole: A. It is longer acting B. Its absorption from stomach is not dependent on gastric acidity C. It produces fewer side effects D. All of the above
Last Answer : D. All of the above
Description : Which antifungal agent is effective in both dermatophytosis as well as systemic mycosis: A. Amphotericin B B. Griseofulvin C. Clotrimazole D. Ketoconazole
Last Answer : D. Ketoconazole
Description : Choose the drug that can be used orally for intestinal amoebiasis, intravaginally for trichomonas vaginitis and topically for dermatophytosis: A. Quiniodochlor B. Furazolidone C. Ornidazole D. Hamycin
Last Answer : A. Quiniodochlor
Description : Antifungal drugs, such as_ __, inhibit proper formation of a. Miconazole; A Plasma Membrane b. Griseofulvin; Dna c. Ketoconazole; A Cell Wall d. Tiucytosine; A Rnicrotubule
Last Answer : d. Tiucytosine; A Rnicrotubule
Description : What is true about use of amphotericin B in kala azar: A. It is currently the drug of choice B. It is more effective than ketoconazole C. It is indicated only in cases not responding to sodium stibogluconate D. Both 'B' and 'C' are correct
Last Answer : D. Both 'B' and 'C' are correct
Description : The drug of choice for Kala azar is: A. Pentamidine B. Amphotericin B C. Sodium stibogluconate D. Ketoconazole
Last Answer : C. Sodium stibogluconat
Description : Select the drug that is fungicidal and acts by inhibiting fungal squalene epoxidase enzyme: A. Ketoconazole B. Terbinafine C. Tolnaftate D. Hamycin
Last Answer : B. Terbinafine
Description : The drug of choice for monilial diarrhoea is: A. Flucytosine B. Nystatin C. Natamycin D. Ketoconazole
Last Answer : B. Nystatin
Description : The following prokinetic drug has been implicated in causing serious ventricular arrhythmias, particularly in patients concurrently receiving erythromycin or ketoconazole: A. Domperidone B. Cisapride C. Mosapride D. Metoclopramide
Last Answer : B. Cisapride
Description : Fluconazole is more effective than intraconazole in the following systemic fungal disease: A. Pulmonary histoplasmosis B. Cryptococcal meningitis C. Nonmeningeal blastomycosis D. Disseminated sporotrichosis
Last Answer : B. Cryptococcal meningitis
Description : The following are topical antifungal drugs except: A. Ciclopirox olamine B. Tolnaftate C. Crotamiton D. Terbinafine
Last Answer : C. Crotamiton
Description : The most probable mechanism of action of imidazole antifungal drugs is: A. They bind to ergosterol in fungal cell membrane and make it leaky B. They interfere with ergosterol synthesis by fungi C. They interfere with fungal mitosis D. They block oxidative phosphorylation in fungi
Last Answer : B. They interfere with ergosterol synthesis by fungi
Description : Indicate the antifungal antibiotic which is used intravenously for systemic mycosis: A. Griseofulvin B. Nystatin C. Amphotericin B D. Hamycin
Last Answer : C. Amphotericin
Description : The distinctive feature of terbinafine is: A. It is highly effective in histoplasmosis B. It can be used topically as well as orally for dermatophytosis C. It inhibits Mucor and Aspergillus as well D. Applied intravaginally it cures both candida as well as trichomonas vaginitis
Last Answer : B. It can be used topically as well as orally for dermatophytosis
Description : Features of clindamycin include the following: A. It is primarily active against aerobic gram negative bacilli B. It can be used topically to treat infected acne vulgaris C. It is not absorbed orally D. It is used to treat pseudomembranous enterocolitis
Last Answer : B. It can be used topically to treat infected acne vulgaris
Description : The following antihypertensive is used topically to treat alopacia areata: A. Hydralazine B. Prazosin C. Minoxidil D. Indapamide
Last Answer : C. Minoxidil
Description : Select the correct statement about tibolone: A. It is an antiestrogen used for palliative treatment of carcinoma breast B. It is an estrogenic + progestational steroid used for hormone replacement ... for male pattern baldness D. It is a nonsteroidal estrogen used topically for senile vaginitis
Last Answer : B. It is an estrogenic + progestational steroid used for hormone replacement therapy in postmenopausal women
Description : Dorzolamide is a: A. Topically applied ocular carbonic anhydrase inhibitor B. Second generation sulfonylurea hypoglycaemic C. Topical sulfonamide antibacterial D. Luminal amoebicide
Last Answer : A. Topically applied ocular carbonic anhydrase inhibitor
Description : Which of the following is a prodrug of adrenaline used topically in glaucoma: A. Brimonidine B. Dipivefrine C. Phenylpropanolamine D. Dorzolamide
Last Answer : B. Dipivefrine
Description : The following statement is true about ketoconazole except: A. It is less toxic than amphotericin B B. It produces a slower response than amphotericin B in systemic mycosis C. Given orally it is the first line treatment for vaginal candidiasis D. It is not effective in fungal meningitis
Last Answer : C. Given orally it is the first line treatment for vaginal candidiasis
Description : Adverse effects of ketoconazole include the following except: A. Gynaecomastia B. Oligozoospermia C. Kidney damage D. Menstrual irregularities
Last Answer : C. Kidney damage
Description : Circulating testosterone levels in men are elevated during treatment with: A. Danazol B. Finasteride C. Flutamide D. Ketoconazole
Last Answer : C. Flutamide
Description : The following second generation anti-histaminic is not likely to produce ventricular arrhythmias when administered along with ketoconazole: A. Mizolastine B. Ebastine C. Terfenadine D. Astemizole
Last Answer : A. Mizolastine
Description : Irrespective of the etiology of a corneal ulcer, the drug always indicated is: a. Corticosteroid b. Atropine c. Antibiotics d. Antifungal
Last Answer : ANSWER: B
Description : To be used as a topically applied ocular beta blocker a drug should have the following properties except: A. Strong local anaesthetic activity B. High lipophilicity C. High ocular capture D. Low systemic activity
Last Answer : A. Strong local anaesthetic activity
Description : Which drug is used to cure Glaucoma? (1) Fexofenadine (2) Ketoconazole (3) Latanoprost (4) Ibuprofen
Last Answer : (3) Latanoprost Explanation: Latanoprost, sold under the brand name Xalatan, is a medication used to treat increased pressure inside the eye. This includes ocular hypertension and open angle glaucoma.
Description : The following drug adverse effect is specially noted in men compared to women: A. Tardive dyskinesia due to neuroleptics B. Levodopa induced abnormal movements C. Ampicillin induced loose motions D. Ketoconazole induced loss of libido
Last Answer : D. Ketoconazole induced loss of libido
Description : Choose the correct statement about topotecan: A. It is a DNA topoisomerase I inhibitor which causes single strand DNA breaks B. It is a cell cycle specific anticancer drug C. It is a COMT-inhibitor used in advanced parkinsonism D. Both 'A' and 'B' are correc
Last Answer : D. Both 'A' and 'B' are correct
Description : Choose the most effective drug for mild intestinal amoebiasis and asymptomatic cyst passers: A. Metronidazole B. Emetine C. Quiniodochlor D. Diloxanide furoate
Last Answer : D. Diloxanide furoate
Description : Choose the correct statement(s) about metronidazole: A. It is a first line drug for amoebic dysentery as well as amoebic liver abscess B. It affords the most rapid symptom relief in amoebic dysentery C. It is the most effective drug in eradicating amoebic cysts from the colon D. All of the above
Last Answer : A. It is a first line drug for amoebic dysentery as well as amoebic liver abscess
Description : Choose the antimalarial drug effective against multidrug resistant P. falciparum, which rapidly terminates an attack of malarial fever, but has a short duration of action, so that recrudescence is common: A. Proguanil B. Mefloquine C. Amodiaquine D. Artemisinin
Last Answer : D. Artemisinin
Description : Choose the drug whose single oral dose affords clinical cure of uncomplicated malaria caused by chloroquine sensitive/resistant P.falciparum as well as P. vivax: A. Quinine B. Mefloquine C. Artesunate D. Proguanil
Last Answer : B. Mefloquine
Description : Choose the correct statement about famciclovir: A. It is active against acyclovir resistant strains of herpes simplex virus B. It does not need conversion to an active metabolite C. It is used orally to treat genital herpes simplex D. It is the drug of choice for cytomegalovirus retinitis
Last Answer : C. It is used orally to treat genital herpes simplex
Description : Choose the correct statement about rifampin: A. It is the most active drug on slow growing tubercle bacilli B. Its antitubercular efficacy is lower than that of isoniazid C. It is active against many atypical mycobacteria D. It does not effectively cross blood-CSF barrier
Last Answer : C. It is active against many atypical mycobacteria
Description : Choose the correct statement in relation to treatment of urinary tract infection (UTI): A. Majority of UTIs are caused by gram positive bacteria B. Smaller doses of the antimicrobial agent ... drug gets concentrated in urine D. Most acute UTIs are treated with a combination antimicrobial regimen
Last Answer : B. Smaller doses of the antimicrobial agent suffice for lower UTI
Description : Choose the antiulcer drug that inhibits gastric acid secretion, stimulates gastric mucus and bicarbonate secretion and has cytoprotective action on gastric mucosa: A. Misoprostol B. Sucralfate C. Carbenoxolone sodium D. Colloidal bismuth subcitrate
Last Answer : A. Misoprostol
Description : Choose the drug which blocks basal as well as stimulated gastric acid secretion without affecting cholinergic, histaminergic or gastrin receptors: A. Famotidine B. Loxatidine C. Omeprazole D. Pirenzepine
Last Answer : C. Omeprazole
Description : Choose the drug which alters surface receptors on platelet membrane to inhibit aggregation, release reaction and to improve platelet survival in extracorporeal circulation: A. Dipyridamole B. Ticlopidine C. Aspirin D. Heparin
Last Answer : B. Ticlopidine
Description : Choose the most suitable antihypertensive drug for a 45-year-old male company executive who has a travelling job. His blood pressure is 160/100 mm Hg, and he is a diabetic ... → rebound hypertension. Hydrochlorothiazide: May worsen diabetes; more likely to produce weakness, fatigue and impotenc
Last Answer : B. Enalapril
Description : Choose the correct statement about trimetazidine: A. It is a novel calcium channel blocker B. It improves tissue perfusion by modifying rheological property of blood C. It is an antianginal drug which acts by nonhaemodynamic mechanisms D. Both 'A' and 'B' are correct
Last Answer : C. It is an antianginal drug which acts by nonhaemodynamic mechanisms
Description : Choose the antiarrhythmic drug which prolongs action potential, can aggravate atrioventricular block but not heart failure, and has broad spectrum utility in acute as well as chronic, and ventricular as well as supraventricular arrhythmias: A. Quinidine B. Amiodarone C. Mexiletine D. Diltiazem
Last Answer : B. Amiodarone