Description : Which antifungal agent is effective in both dermatophytosis as well as systemic mycosis: A. Amphotericin B B. Griseofulvin C. Clotrimazole D. Ketoconazole
Last Answer : D. Ketoconazole
Description : Select the antifungal drug which is administered only by the oral route: A. Amphotericin B B. Ketoconazole C. Griseofulvin D. Tolnaftate
Last Answer : C. Griseofulvin
Description : The following statement is true about ketoconazole except: A. It is less toxic than amphotericin B B. It produces a slower response than amphotericin B in systemic mycosis C. Given orally it is the first line treatment for vaginal candidiasis D. It is not effective in fungal meningitis
Last Answer : C. Given orally it is the first line treatment for vaginal candidiasis
Description : Which one of the following pairs is incorrectly matched as to antibiotic and use? a. Penicillin-gram-positive bacteria b. Nystatin-fungi c. Tetracycline-viruses d. Griseofulvin-fungi
Last Answer : c. Tetracycline-viruses
Description : A 55-year-old renal transplant patient has been hospitalized in a Surgical Intensive Care Unit, receiving a prolonged course of antibiotics following an attack of acute cholecystitis. The ... suggest a dosage reduction in immunosuppressive agents until the infection can be adequately controlled
Last Answer : Answer: a, d Infections due to fungal pathogens have become increasingly common during the past decade, frequently occurring in patients undergoing prolonged hospitalization in the Surgical ... agents should be discontinued until evidence of infection is absolutely controlled or is eradicated
Description : The following drugs are effective in systemic mycosis except: A. Terbinafine B. Itraconazole C. Ketoconazole D. Fluconazol
Last Answer : A. Terbinafine
Description : The following is applicable to itraconazole except: A. It has largely replaced ketoconazole for treatment of systemic mycosis B. It does not inhibit human steroid hormone synthesis C. It is ... the treatment of fungal meningitis D. It can interact with terfenadine to produce ventricular arrhythmias
Last Answer : C. It is preferred for the treatment of fungal meningitis
Description : Prolonged oral therapy with the following antibiotic can damage intestinal villi resulting in steatorrhoea and loose motions: A. Ampicillin B. Tetracycline C. Neomycin D. Nystatin
Last Answer : C. Neomycin
Description : Antifungal drugs, such as_ __, inhibit proper formation of a. Miconazole; A Plasma Membrane b. Griseofulvin; Dna c. Ketoconazole; A Cell Wall d. Tiucytosine; A Rnicrotubule
Last Answer : d. Tiucytosine; A Rnicrotubule
Description : Regarding the recently introduced lipid formulation of amphotericin B, which one of the following statements is accurate? (a) Affinity of amphotericin B for these lipids is greater than ... (e) They have wider spectrums of antifungal activity than conventional formulations of amphotericin B
Last Answer : Ans: D
Description : Choose the drug that can be used orally for intestinal amoebiasis, intravaginally for trichomonas vaginitis and topically for dermatophytosis: A. Quiniodochlor B. Furazolidone C. Ornidazole D. Hamycin
Last Answer : A. Quiniodochlor
Description : Select the drug that is fungicidal and acts by inhibiting fungal squalene epoxidase enzyme: A. Ketoconazole B. Terbinafine C. Tolnaftate D. Hamycin
Last Answer : B. Terbinafine
Description : Indicate the attribute that is common to both polymyxin B and bacitracin: A. Both are active against gram negative bacteria B. Both are too toxic for systemic use C. Both act by inhibiting bacterial cell wall synthesis D. Both a
Last Answer : B. Both are too toxic for systemic use
Description : How would you treat Denture Stomatitis A. Tetracycline B. Systemic penicillin C. Nystatin
Last Answer : C. Nystatin
Description : Griseofulvin is indicated in: A. All types of tinea infection B. Onychomycosis C. Pityriasis versicolor D. Both ‘B’ and ‘C
Last Answer : B. Onychomycosis
Description : Prolonged oral therapy with the following antibiotic can damage intestinal villi resulting in statorrhoea and loose motions (a) Ampicillin (b) Tetracycline (c) Neomycin (d) Nystatin
Last Answer : Ans: C
Description : The drug of choice for monilial diarrhoea is: A. Flucytosine B. Nystatin C. Natamycin D. Ketoconazole
Last Answer : B. Nystatin
Description : ttt of foliculitis after shaving the bread a- oral steroid b- topical steroid c -oral antibiotics may be there was topical antifungal but no topical antibiotic choice
Last Answer : c -oral antibiotics
Description : The following are topical antifungal drugs except: A. Ciclopirox olamine B. Tolnaftate C. Crotamiton D. Terbinafine
Last Answer : C. Crotamiton
Description : The only azole antifungal drug which has some activity against moulds like Aspergillus is: A. Itraconazole B. Fluconazole C. Miconazole D. Ketoconazole
Last Answer : A. Itraconazole
Description : Choose the azole antifungal drug which is used only topically: A. Ketoconazole B. Fluconazole C. Itraconazole D. Econazole
Last Answer : D. Econazole
Description : The most probable mechanism of action of imidazole antifungal drugs is: A. They bind to ergosterol in fungal cell membrane and make it leaky B. They interfere with ergosterol synthesis by fungi C. They interfere with fungal mitosis D. They block oxidative phosphorylation in fungi
Last Answer : B. They interfere with ergosterol synthesis by fungi
Description : What is true about use of amphotericin B in kala azar: A. It is currently the drug of choice B. It is more effective than ketoconazole C. It is indicated only in cases not responding to sodium stibogluconate D. Both 'B' and 'C' are correct
Last Answer : D. Both 'B' and 'C' are correct
Description : The drug of choice for Kala azar is: A. Pentamidine B. Amphotericin B C. Sodium stibogluconate D. Ketoconazole
Last Answer : C. Sodium stibogluconat
Description : The newer lipid formulations of amphotericin B differ from the conventional formulation in the following respects except: A. They are more efficacious B. They produce milder acute reaction C. They are less nephrotoxic D. They produce milder anaemia
Last Answer : A. They are more efficacious
Description : The most important toxicity of amphotericin B is: A. Nephrotoxicity B. Neurotoxicity C. Hepatotoxicity D. Bone marrow depression
Last Answer : A. Nephrotoxicity
Description : Amphotericin B is not effective in the following fungal disease: A. Cryptococcosis B. Histoplasmosis C. Blastomycosis D. Dermatophytosis
Last Answer : D. Dermatophytosis
Description : In addition to fungi, amphotericin B is active against the following pathogen: A. Anaerobic bacteria B. Giardia C. Leishmania D. Rickettsiae
Last Answer : C. Leishmania
Description : Which of the following statement(s) is/are true concerning the role of antibiotics in wound care? a. Systemic antibiotics are indicated for all open wounds b. Bacterial resistance can occur with ... of tissue on quantitative analysis d. Silver sulfadiazine is useful only for the management of burns
Last Answer : Answer: c The role of antibiotics in wound care is controversial. All open wounds are colonized with bacteria. Only when surrounding tissue is invaded (cellulitis) are systemic antibiotics clearly ... of relevant drug-resistant plasmids in bacteria, and its low cost make it a good choice
Description : Two central incisors on a radiograph are showing with what looks like eye drop radiolucency. You decided to start endodontic treatment on these teeth but when you tried to open access to the root ... and start a permanent restoration. B. Start systemic antibiotic C. Try to ream and file canals
Last Answer : C. Try to ream and file canals
Description : A female patient comes to you complaining of persistent pain in a heavily restored central incisor; you suspect pulpitis and you have been told that she is in transit leaving by plane ... B. Pulp extirpation and obturate with Ledermix dressings C. Prescribe analgesics and systemic antibiotic
Last Answer : B. Pulp extirpation and obturate with Ledermix dressings
Description : All of the following should be considered for systemic antibiotic except: A. Extraction of tooth with acute dento alveolar abscess B. Necrotic ulcerative gingivitis (ANUG) unless it is acute. C. ... of 38 or 48 with acute pericoronitis D. Full mouth extraction for a patient with perio disease
Last Answer : B. Necrotic ulcerative gingivitis (ANUG) unless it is acute.
Description : The prognosis of teeth with apical resorption is : A. Poor B. Good if apex can be sealed C. Dependant upon periapical surgery D. Contingent upon systemic antibiotic therapy combined with treatment of the canal
Last Answer : B. Good if apex can be sealed
Description : Fluconazole is more effective than intraconazole in the following systemic fungal disease: A. Pulmonary histoplasmosis B. Cryptococcal meningitis C. Nonmeningeal blastomycosis D. Disseminated sporotrichosis
Last Answer : B. Cryptococcal meningitis
Description : Teicoplanin has the following feature(s): A. Antimicrobial activity and indications similar to vancomycin B. Long elimination half-life C. Efficacy in systemic infections by oral route D. Both ‘A’ and ‘B’ are correct
Last Answer : D. Both ‘A’ and ‘B’ are correct
Description : What is the most important reason for the restricted use of systemic chloramphenicol: A. Emergence of chloramphenicol resistance B. Its potential to cause bone marrow depression C. Its potential to cause superinfections D. Its potential to inhibit the metabolism of many drugs
Last Answer : B. Its potential to cause bone marrow depression
Description : The following quinolone antimicrobial agent is not useful in systemic infections: A. Lomefloxacin B. Ofloxacin C. Nalidixic acid D. Pefloxacin
Last Answer : C. Nalidixic acid
Description : The therapeutic effect of sulfasalazine in ulcerative colitis is exerted by: A. Inhibitory action of the unabsorbed drug on the abnormal colonic flora B. Breakdown of the drug in ... locally C. Release of sulfapyridine having antibacterial property D. Systemic immunomodulatory action of the drug
Last Answer : B. Breakdown of the drug in colon to release 5-aminosalicylic acid which suppresses inflammation locally
Description : Choose the correct statement about magaldrate: A. It is a mixture of magnesium and aluminium hydroxides B. It has a rapid as well as sustained acid neutralizing action C. Its acid neutralizing capacity is 2 m Eq/g D. It causes systemic alkalosis
Last Answer : B. It has a rapid as well as sustained acid neutralizing action
Description : The following is true of procainamide except: A. It generates an active metabolite in the body B. Its plasma half-life is longer than that of quinidine C. On long-term use, it ... erythematosus like illness D. It is effective in many cases of ventricular extrasystoles, not responding to lignocaine
Last Answer : A. Disopyramide
Description : Angiotensin converting enzyme inhibitors reduce the following haemodynamic parameters in congestive heart failure except: A. Systemic vascular resistance B. Right atrial pressure C. Cardiac output D. Heart rate × pressure product
Last Answer : C. Cardiac output
Description : Morphine affords symptomatic relief of dyspnoea in acute left ventricular failure by the following mechanisms except: A. Bronchodilatation B. Depression of respiratory centre C. Reduction in cardiac preload D. Shift of blood from pulmonary to systemic circuit
Last Answer : A. Bronchodilatation
Description : Oxethazaine is used for anaesthetizing gastric mucosa because: A. It is not absorbed from the gastrointestinal tract B. It remains largely unionized in acidic medium C. It is highly ionized in acidic medium D. It produces no systemic effects even at high doses
Last Answer : B. It remains largely unionized in acidic medium
Description : Adrenaline added to local anaesthetic solution for infiltration anaesthesia affords the following except: A. Prolongs the duration of local anaesthesia B. Makes the injection less painful C. Provides a more bloodless field for surgery D. Reduces systemic toxicity of the local anaesthetic
Last Answer : B. Makes the injection less painful
Description : After chronic systemic therapy, withdrawal of corticosteroids should be gradual because: A. Corticosteroids produce psychological dependence B. Abrupt withdrawal may reactivate the underlying disease C. Abrupt withdrawal produces rebound hypertension D. All of the above are correct
Last Answer : B. Abrupt withdrawal may reactivate the underlying disea
Description : In an asthma patient treated with systemic corticosteroids, bronchodilator drugs: A. Are not needed B. Are contraindicated C. May be used on ‘as and when required’ basis D. Are ineffective
Last Answer : C. May be used on ‘as and when required’ basis
Description : Adrenaline is inactive orally because it is: A. Not absorbed from the gastrointestinal tract B. Destroyed by gastric acid C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation D. Taken up by adrenergic nerve endings of the intestinal wall, liver and lungs
Last Answer : C. Completely metabolized in the intestinal mucosa and liver before reaching systemic circulation
Description : Inhaled ipratropium bromide has the following advantages except: A. It does not alter respiratory secretions B. It does not depress airway mucociliary clearance C. It has faster onset of bronchodilator action than inhaled salbutamol D. It only rarely produces systemic side effects
Last Answer : C. It has faster onset of bronchodilator action than inhaled salbutamol
Description : The following allergic drug reaction is caused by circulating antibodies: A. Serum sickness B. Anaphylactic shock C. Systemic lupus erythematosus D. Angioedema
Last Answer : A. Serum sickness