Description : Aminotransferases usually require the following for their activity : (A) Niacinamide (B)Vitamin B12 (C) Pyridoxal phosphate (D) Thiamine
Last Answer : (C) Pyridoxal phosphate
Description : Nicotinic action of acetylcholine is blocked by the drug (A) Atropine (B) Carvedilol (C) Neostigmine ( D ) d-Tubocurarine
Last Answer : ( D ) d-Tubocurarine
Description : Magenta tongue is found in the deficiency of the vitamin (A) Riboflavin (B) Thiamin (C) Nicotinic acid (D) Pyridoxine
Last Answer : Answer : A
Last Answer : (A) Riboflavin
Description : Coenzyme A contains the vitamin: (A) Riboflavin (B) Pantothenic acid (C) Pyridoxine (D) Thiamine
Last Answer : Answer : B
Description : Pernicious anaemia in humans is caused by the deficiency of (a) Pyridoxine (Vitamin B6) (b) Cyanocobalamin (Vitamin B12) (c) Thiamine (Vitamin B1) (d) Pantothenic acid (Vitamin B5)
Last Answer : Ans:(b)
Description : In thiazides following substituent is essential for diuretic activity : (A) Chloro group at position 6 (B) Methyl group at position 2 (C) Sulphamoyl group at position 7 (D) Hydrophobic group at position 3
Last Answer : (C) Sulphamoyl group at position 7
Description : Which ot the following vitamin is involved in coenzyme function in transaminations? (A) Nicotinamide (B) Pyridoxine (C) Thiamine (D) Riboflavin
Description : The sulphur containing vitamins among the following B Vitamin is (A) Thiamine (B) Riboflavin (C) Niacin (D) Pyridoxine
Description : The following vitamin is involved in coenzyme function in transaminations: (A) Nicotinamide (B) Pyridoxine (C) Thiamine (D) Riboflavin
Description : The sulphur-containing vitamins among the following B-Vitamin is (A) Thiamine (B) Riboflavin (C) Niacin (D) Pyridoxine
Description : Defeciency of following vitamin decreases hemoglobin production ? A. Biotin B. Thiamine C. Niacin D. Pyridoxine (Answer) E. None of these
Last Answer : D. Pyridoxine (Answer)
Description : Which ot the following vitamin is involved in coenzyme function in tansaminations? (A) Nicotinamide (B) Pyridoxine (C) Thiamine (D) Riboflavin
Last Answer : B) Pyridoxine
Description : The enzyme -ketoglutarate dehydrogenase in the citric acid cycle requires (A) Lipoate (B) Folate (C) Pyridoxine (D) Inositol
Description : Increased carbohydrate consumption increases the dietary requirement for (A) Thiamine (B) Riboflavine (C) Pyridoxine (D) Folic acid
Description : Convulsive episodes occur when there is a severe deficiency of: (A) Pyridoxine (B) Folic acid (C) Thiamine (D) Riboflavin
Description : Convulsive episodes occur when there is a severe deficiency of (A) Pyridoxine (B) Folic acid (C) Thiamine (D) Riboflavin
Last Answer : (A) Pyridoxine
Description : A patient of megaloblastic anaemia was treated with oral folic acid 5 mg daily. After 2 weeks he reported back with cognitive deficit, sensory disturbance, depressed knee jerk, while ... therapy has unmasked pyridoxine deficiency D. Patient has folate reductase abnormality in the nervous system
Last Answer : D. Patient has folate reductase abnormality in the nervous system
Description : Gammaxine is an antimetabolite of (A) Thiamine (B) Riboflavin (C) Pyridoxin (D) Inositol
Last Answer : Answer : D
Description : Gammaxane is an antimetabolite of (A) Thiamine (B) Riboflavin (C) Pyridoxin (D) Inositol
Description : In nail polish, following polymer is used as a film-former : (A) Nitrocellulose (B) Polylactic acid (C) Hydroxypropyl methylcellulose (D) Cellulose acetate phthalate
Last Answer : (A) Nitrocellulose
Description : Artemisinin contains the following group in its structure : (A) an endoperoxide (B) an exoperoxide (C) an epoxide (D) an acid hydrazide
Last Answer : (A) an endoperoxide
Description : Amitryptyline is synthesized from the following starting material : (A) Phthalic anhydride (B) Terephthalic acid (C) Phthalamic acid (D) Phthalimide
Last Answer : (B) Terephthalic acid
Description : Identify the one rational combination which has clinical benefit : (A) Norfloxacin – Metronidazole (B) Alprazolam - Paracetamol (C) Cisapride – Omeprazole (D)Amoxycillin - Clavulanic acid
Last Answer : (D)Amoxycillin - Clavulanic acid
Description : The rate limiting step in cholesterol biosynthesis is one of the followings : (A) LDL-receptor concentration (B) VLDL secretion (C) Mevalonic acid formation (D) Co-enzyme A formation
Last Answer : (C) Mevalonic acid formation
Description : Alkaloids are NOT precipitated by (A) Mayer's reagent (B) Dragendroff Reagent (C) Picric acid (D) Millon's reagent
Last Answer : (D) Millon's reagent
Description : Choose the right combination: (A) Quinine', antimalarial, isoquinoline alkaloid (B) Reserpine, -antihypertensive, indole alkaloid (C) Quantitative microscopy, stomatal number, myrrh (D) Palmitic acid, salicylic acid , fatty acids
Last Answer : (B) Reserpine, -antihypertensive, indole alkaloid
Description : Thioglycolic acid-like compounds have applications in following type of cosmetic formulations : (A) Depilatory preparations (B) Epilatory preparations (C) Vanishing creams (D) Skin tan preparations
Last Answer : (A) Depilatory preparations
Description : An isosteric replacement for carboxylic acid group is (A) pyrrole (B) isoxazole (C) phenol (D) tetrazole
Last Answer : (D)tetrazole
Description : Which one of the followings is a plasminogen activator? (A) Tranexamic acid (B) Streptokinase (C) Aminocaproic acid (D) None of the above
Last Answer : (B) Streptokinase
Description : Transketolase activity is affected in (A) Bitoin deficiency (B) Pyridoxine deficiency (C) PABA deficiency (D) Thiamine deficiency
Description : Transketolase activity is affected in (A) Biotin deficiency (B) Pyridoxine deficiency (C) PABA deficiency (D) Thiamine deficiency
Last Answer : B
Last Answer : D) Thiamine deficiency
Description : Which group of three of the following five statements (1-5) contain all three correct statements regarding beri-beri? 1. A crippling disease prevalent among the native population of sub-Saharan Africa. 2. A deficiency disease caused by lack ... and 5 (b) 1, 2 and 4 (c) 1, 3 and 5 (d) 2, 3 and 5
Last Answer : a) 2, 4 and 5
Description : In which of the following techniques the sample is kept below triple point? (A) Lyophilization (B) Spray drying (C) Spray congealing (D) Centrifugation
Last Answer : (A) Lyophilization
Description : Which one of the following is NOT an ex-officio member of Pharmacy Council of India? (A) The Director General of Health Services (B) The Director of Central Drugs Laboratory (C) The Drugs Controller General of India (D) The Director of Pharmacopoeia Laboratory
Last Answer : (D) The Director of Pharmacopoeia Laboratory
Description : It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 hr and Vd of 5 L. The dose required in a sustained release product will be (A) 600 mg (B) 300 mg (C) 30 mg (D) 60 mg
Last Answer : (B) 300 mg
Description : The Volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be (A)10 L (B) 100 L (C) 1.0 L (D) 0.10 L
Last Answer : (A)10 L
Description : How many mL of a 1:500 w/v stock solution should be used to make 5 liters of 1:2000 w/v solution? (A) 750 mL (B) 1000 mL (c) 1250 mL (D) 1500 mL
Last Answer : (c) 1250 mL
Description : Class 100 area is referred to (A) Manufacturing area (B) Aseptic area (C) Clean room (D) Ware house
Last Answer : (B) Aseptic area
Description : Geriatric population should be included in the following Phase of clinical trials (A) Phase I (B) Phase II (C) Phase III (D) Phase
Last Answer : (B) Phase II
Description : A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram hr/mL, respectively. The absolute availability of the drug through oral administration is : (A) 125% (B) 250 % (C) 12.5% (D) 1.25%
Last Answer : (C) 12.5%
Description : Rabies vaccine (living) is prepared using (A) Sheep blood (B) Mice lymph (C) Horse plasma (D) Fertile eggs
Last Answer : (D) Fertile eggs
Description : Drugs in suspensions and semi-solid formulations always degrade by (A) first order kinetics (B)second order kinetics (C) zero order kinetics (D) non-linear kinetics
Last Answer : (C) zero order kinetics
Description : The following protein/polypeptide has a quaternary structure : (A) cc-Chymotrypsin (B) Hemoglobin (C) Insulin (D) Myoglobin
Last Answer : (B) Hemoglobin
Description : Many xenobiotics are oxidized by cytochrome P450 in order to (A) increase their biological activity (B) increase their disposition in lipophilic compartments of the body (C) increase their aqueous solubility (D) all of the above
Last Answer : (D) all of the above
Description : The temperature condition for storage of drug products under cold temperature is given as : (A) temperature between 8°C and 25°C (B) temperature below 20 C (C) temperature at 0°C (D) temperature between 2c C and S: C
Last Answer : (D) temperature between 2c C and S: C
Description : Drugs following one compartment open model pharmacokinetics eliminate (A) bi-exponentially (B) tri-exponentially (C) non-exponentially (D) mono-exponentially
Last Answer : (D) mono-exponentially
Description : Coulter counter is used in determination of (A) particle surface area (B) particle size (C) particle volume (D)all of A, B, C
Last Answer : (D)all of A, B, C