Artemisinin contains the following group in its structure :
(A) an endoperoxide (B) an exoperoxide
(C) an epoxide (D) an acid hydrazide

1 Answer

Answer :

(A) an endoperoxide

Related questions

Description : Identify the drug which is NOT used in the treatment of malaria caused by Plasmodium falciparum : (A.) Artemisinin (B) Primaquine (C) Quinine (D) Mefloquine

Last Answer : (B) Primaquine

Description : An isosteric replacement for carboxylic acid group is (A) pyrrole (B) isoxazole (C) phenol (D) tetrazole

Last Answer : (D)tetrazole

Description : One mg of Lycopodium spores used in quantitative microscopy contains an average of (A) 94,000 spores (B) 92,000 spores (C) 90,000 spores (D) 91,000 spores

Last Answer : (A) 94,000 spores

Description : The following protein/polypeptide has a quaternary structure : (A) cc-Chymotrypsin (B) Hemoglobin (C) Insulin (D) Myoglobin

Last Answer : (B) Hemoglobin

Description : In thiazides following substituent is essential for diuretic activity : (A) Chloro group at position 6 (B) Methyl group at position 2 (C) Sulphamoyl group at position 7 (D) Hydrophobic group at position 3

Last Answer : (C) Sulphamoyl group at position 7

Description : In nail polish, following polymer is used as a film-former : (A) Nitrocellulose (B) Polylactic acid (C) Hydroxypropyl methylcellulose (D) Cellulose acetate phthalate

Last Answer : (A) Nitrocellulose

Description : Amitryptyline is synthesized from the following starting material : (A) Phthalic anhydride (B) Terephthalic acid (C) Phthalamic acid (D) Phthalimide

Last Answer : (B) Terephthalic acid

Description : Identify the one rational combination which has clinical benefit : (A) Norfloxacin – Metronidazole (B) Alprazolam - Paracetamol (C) Cisapride – Omeprazole (D)Amoxycillin - Clavulanic acid

Last Answer : (D)Amoxycillin - Clavulanic acid

Description : The rate limiting step in cholesterol biosynthesis is one of the followings : (A) LDL-receptor concentration (B) VLDL secretion (C) Mevalonic acid formation (D) Co-enzyme A formation

Last Answer : (C) Mevalonic acid formation

Description : Alkaloids are NOT precipitated by (A) Mayer's reagent (B) Dragendroff Reagent (C) Picric acid (D) Millon's reagent

Last Answer : (D) Millon's reagent

Description : Choose the right combination: (A) Quinine', antimalarial, isoquinoline alkaloid (B) Reserpine, -antihypertensive, indole alkaloid (C) Quantitative microscopy, stomatal number, myrrh (D) Palmitic acid, salicylic acid , fatty acids

Last Answer : (B) Reserpine, -antihypertensive, indole alkaloid

Description : Thioglycolic acid-like compounds have applications in following type of cosmetic formulations : (A) Depilatory preparations (B) Epilatory preparations (C) Vanishing creams (D) Skin tan preparations

Last Answer : (A) Depilatory preparations

Description : Which one of the followings is a plasminogen activator? (A) Tranexamic acid (B) Streptokinase (C) Aminocaproic acid (D) None of the above

Last Answer : (B) Streptokinase

Description : The vitamin essential in tissue culture medium is (A) Pyridoxine (B) Thiamine (C) Nicotinic acid (D) Inositol

Last Answer : (B) Thiamine

Description : Epoxy resin is a polymer containing two or more groups of the bellow fig. is called epoxide group or ethoxyline group. It is a (A) Polyamide & an elastomer (B) Good adhesive (C) Surface coating agent (D) Both (B) and (C)

Last Answer : (D) Both (B) and (C)

Description : Purity of water can be assessed by determining one of its following properties instrumentally : (A) pH (B) Refractivity (C) Viscosity (D) Conductivity

Last Answer : (D)Conductivity

Description : X-ray crystallographic analysis of an optically active compound determines its (A) Optical rotatory dispersive power (B) Absolute configuration (C) Relative configuration (D) Optical purity

Last Answer : (B) Absolute configuration

Description : Gingkgo biloba is used for its (A) Expectorant activity (B) Lipid lowering activity (C) PAF antagonistic activity (D)Antidepressant activity

Last Answer : (C) PAF antagonistic activity

Description : In which of the following techniques the sample is kept below triple point? (A) Lyophilization (B) Spray drying (C) Spray congealing (D) Centrifugation

Last Answer : (A) Lyophilization

Description : Which one of the following is NOT an ex-officio member of Pharmacy Council of India? (A) The Director General of Health Services (B) The Director of Central Drugs Laboratory (C) The Drugs Controller General of India (D) The Director of Pharmacopoeia Laboratory

Last Answer : (D) The Director of Pharmacopoeia Laboratory

Description : It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 hr and Vd of 5 L. The dose required in a sustained release product will be (A) 600 mg (B) 300 mg (C) 30 mg (D) 60 mg

Last Answer : (B) 300 mg

Description : The Volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be (A)10 L (B) 100 L (C) 1.0 L (D) 0.10 L

Last Answer : (A)10 L

Description : How many mL of a 1:500 w/v stock solution should be used to make 5 liters of 1:2000 w/v solution? (A) 750 mL (B) 1000 mL (c) 1250 mL (D) 1500 mL

Last Answer : (c) 1250 mL

Description : Class 100 area is referred to (A) Manufacturing area (B) Aseptic area (C) Clean room (D) Ware house

Last Answer : (B) Aseptic area

Description : Geriatric population should be included in the following Phase of clinical trials (A) Phase I (B) Phase II (C) Phase III (D) Phase

Last Answer : (B) Phase II

Description : A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram hr/mL, respectively. The absolute availability of the drug through oral administration is : (A) 125% (B) 250 % (C) 12.5% (D) 1.25%

Last Answer : (C) 12.5%

Description : Rabies vaccine (living) is prepared using (A) Sheep blood (B) Mice lymph (C) Horse plasma (D) Fertile eggs

Last Answer : (D) Fertile eggs

Description : Drugs in suspensions and semi-solid formulations always degrade by (A) first order kinetics (B)second order kinetics (C) zero order kinetics (D) non-linear kinetics

Last Answer : (C) zero order kinetics

Description : Many xenobiotics are oxidized by cytochrome P450 in order to (A) increase their biological activity (B) increase their disposition in lipophilic compartments of the body (C) increase their aqueous solubility (D) all of the above

Last Answer : (D) all of the above

Description : The temperature condition for storage of drug products under cold temperature is given as : (A) temperature between 8°C and 25°C (B) temperature below 20 C (C) temperature at 0°C (D) temperature between 2c C and S: C

Last Answer : (D) temperature between 2c C and S: C

Description : Drugs following one compartment open model pharmacokinetics eliminate (A) bi-exponentially (B) tri-exponentially (C) non-exponentially (D) mono-exponentially

Last Answer : (D) mono-exponentially

Description : Coulter counter is used in determination of (A) particle surface area (B) particle size (C) particle volume (D)all of A, B, C

Last Answer : (D)all of A, B, C

Description : Oxidative phosphorylation involves (A) Electron transport system (B) Substrate level phosphorylation (C) Reaction catalyzed by succinic thiokinase in TCA cycle (D) None of the above

Last Answer : (A) Electron transport system

Description : In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their (A) volatility (B) solubility (C)thermal conductivity (D) polarizability

Last Answer : (D) polarizability

Description : Glass transition temperature is detected through (A) X-Ray diffractometery (B) Solution calorimetery (C) Differential scanning calorimetery (D) Thermogravimetric analysis

Last Answer : (C) Differential scanning calorimetery

Description : In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than (A) 350 nm (B) 200 nm (C) 300 nm (D) 250 nm

Last Answer : (A) 350 nm

Description : Streptomycin can NOT be given orally for treatment of tuberculosis because (A) it gets degraded in the GIT (B) it causes severe diarrhoea (C) it causes metallic taste in the mouth (D) it is not absorbed from the GIT

Last Answer : (D) it is not absorbed from the GIT

Description : One of the following statements is NOT true : (A) Accuracy expresses the correctness of measurement (B) Precision represents reproducibility of measurement (C) High degree of precision implies high degree of accuracy also (D) High degree of accuracy implies high degree of precesion also

Last Answer : (C) High degree of precision implies high degree of accuracy also

Description : Indicate the HPLC detector that is most sensitive to change in temperature : (A) PDA detector (B) Refractive Index detector (C) Electrochemical detector (D) Fluorescence detector

Last Answer : (B) Refractive Index detector

Description : Cyclophosphamide as anticancer agent acts as (A) alkylating agent before metabolism (B)alkylating agent after metabolism (C) phosphorylating agent after metabolism (D) DNA intercalating agent

Last Answer : (B)alkylating agent after metabolism

Description : A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is (A) Fluvastatin (B) Cerivastatin (C) Lovastatin (D) Somatostatin

Last Answer : (C) Lovastatin

Description : Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system : (A) Pyrimidine (B)Benzimidazole (C) Benzothiazole (D) Oxindole

Last Answer : (B)Benzimidazole

Description : Selective serotonin reuptake inhibitor is (A) Imipramine (B) Iproniazide (C) Fluoxetin (D)Naphazoline

Last Answer : (C) Fluoxetin

Description : Barbiturates with substitution at the following position possess acceptable hypnotic activity : (A) 1,3-Disubstitution (B) 5,5-Disubstitution (C) 1,5-Disubstitution (D) 3,3-Disubstitution

Last Answer : (B) 5,5-Disubstitution

Description : Chemical nomenclature of procaine is (A) 2-Diethylaminoethyl 4-aminobenzoate (B) N,N-Diethyl 4-aminobenzoate (C) 4-Aminobenzamidoethyl amine (D) 4-Amino-2-diethylaminoethyl benzoate

Last Answer : Ans. A & D

Description : Nicotinic action of acetylcholine is blocked by the drug (A) Atropine (B) Carvedilol (C) Neostigmine ( D ) d-Tubocurarine

Last Answer : ( D ) d-Tubocurarine

Description : The common structural feature amongst the three categories of anticonvulsant drugs barbiturates, succinimides and hydantoins is (A) ureide (B) imidazolidinone (C) dihydropyrimidine (D) tetrahydropyrimidine

Last Answer : (A) ureide

Description : Stevens Johnson sjmdrome is the most common adverse effect associated with one of the following category of drugs : (A) Sulphonamides (B) Macrolides (C) Penicillins (D) Tetracyclines

Last Answer : (A) Sulphonamides

Description : Ganciclovir is mainly used for the treatment of infection caused by (A) Cytomegalovirus (B) Candida albicans (C) Herpes zoster virus (D) Hepatitis B virus

Last Answer : Ans. A & C

Description : Which one of the following drugs is withdrawn from the market due to torsade de pointes? (A) Chlorpromazine (B) Astemizole (C) Haloperidol (D) Domperidone

Last Answer : (B) Astemizole