What is a protein kinase?

What is a protein kinase?
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1 Answer

Answer :

The Cell Cycle Clock: Cyclins and Cyclin-Dependent Kinases
•Two types of regulatory proteins are involved in cell cycle control: cyclins and cyclin-dependent kinases (Cdks)
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Related questions

List two specific cancer treatments, and tell how each treatment works.

Description : List two specific cancer treatments, and tell how each treatment works.

Last Answer : Chemotherapy: Medication usually formulated chemically, and radiation where radiation is directed in certain doses via electromagnetic waves

What are growth factors?

Description : What are growth factors?

Last Answer : •Some external signals are growth factors, proteins released by certain cells that stimulate other cells to divide

What happens if all the chromosome kinetochores are not attached to spindle fibers? When this occurs, which checkpoint is not passed?

Description : What happens if all the chromosome kinetochores are not attached to spindle fibers? When this occurs, which checkpoint is not passed?

Last Answer : •If the cell does not receive the go-ahead signal, it will exit the cycle, not proceeding onto the S phase

What does MPF trigger? What are some specific activities that it triggers?

Description : What does MPF trigger? What are some specific activities that it triggers?

Last Answer : •MPF (maturation-promoting factor) is a cyclin-Cdk complex that triggers a cell’s passage past the G2 checkpoint into the M phase

The activity of cyclin-dependent kinases (CDks) rises and falls. Why?

Description : The activity of cyclin-dependent kinases (CDks) rises and falls. Why?

Last Answer : •The activity of cyclins and Cdks fluctuates during the cell cycle, molecularly, it either receives a message to go ahead or not to go ahead.

What is the Go phase? Describe this phase.

Description : What is the Go phase? Describe this phase.

Last Answer : •If the cell does not receive the go-ahead signal, it will exit the cycle, switching into a nondividing state called the G0 phase

What is a cell cycle checkpoint?

Description : What is a cell cycle checkpoint?

Last Answer : The sequential events of the cell cycle are directed by a distinct cell cycle control system, which is similar to a clock The cell cycle control system is regulated by both internal and ... The clock has specific checkpoints where the cell cycle stops until a go-ahead signal is received

What are the components of the mitotic spindle?

Description : What are the components of the mitotic spindle?

Last Answer : •The mitotic spindle is an apparatus of microtubules that controls chromosome movement during mitosis •During prophase, assembly of spindle microtubules begins in the centrosome, the microtubule organizing center

What is a kinetochore?

Description : What is a kinetochore?

Last Answer : •During prometaphase spindle microtubules appear and are kinetochores (somewhat track like) where sister chromatids travel along them to the centriole (astor, opposite pole) region. .

In animal cells, the assembly of spindle microtubules starts at the centrosome. What is another name for the centrosome?

Description : In animal cells, the assembly of spindle microtubules starts at the centrosome. What is another name for the centrosome?

Last Answer : •During prophase, assembly of spindle microtubules begins in the centrosome, the microtubule organizing center

What are the components of the mitotic spindle? What is the source of these components?

Description : What are the components of the mitotic spindle? What is the source of these components?

Last Answer : •The mitotic spindle is an apparatus of microtubules that controls chromosome movement during mitosis

What occurs in meiosis? How is the chromosome number of daughter cells different?

Description : What occurs in meiosis? How is the chromosome number of daughter cells different?

Last Answer : •Gametes are produced by a variation of cell division called meiosis •Meiosis yields nonidentical daughter cells that have only one set of chromosomes, half as many as the parent cell

What is mitosis?

Description : What is mitosis?

Last Answer : •Eukaryotic cell division consists of Mitosis, the division of the nucleus.

Think carefully, now. How many DNA molecules are in each of your somatic cells?

Description : Think carefully, now. How many DNA molecules are in each of your somatic cells?

Last Answer : •In preparation for cell division, DNA is replicated and the chromosomes condense •Each duplicated chromosome has two sister chromatids, which separate during cell division, but a single DNA MOLECULE

Define chromatin.

Description : Define chromatin.

Last Answer : •Eukaryotic chromosomes consist of chromatin, a complex of DNA and protein that condenses during cell division

How many chromosomes in a human gamete?

Description : How many chromosomes in a human gamete?

Last Answer : 23

Name the two types of gametes.

Description : Name the two types of gametes.

Last Answer : •Sperm and eggs

What is a gamete?

Description : What is a gamete?

Last Answer : •Gametes (reproductive cells: sperm and eggs) have half as many chromosomes as somatic cells

Name two types of somatic cells in your body.

Description : Name two types of somatic cells in your body.

Last Answer : Brain and liver

How many chromosomes are in a human somatic cell?

Description : How many chromosomes are in a human somatic cell?

Last Answer : •Somatic cells (nonreproductive cells) have two sets of chromosomes

What is the meaning of genome?

Description : What is the meaning of genome?

Last Answer : •All the DNA in a cell constitutes the cell’s genome Compare your genome to that of a prokaryotic cell. •A genome can consist of a single DNA molecule (common in prokaryotic cells) or a number of DNA molecules (common in eukaryotic cells)

What is meant by the cell cycle?

Description : What is meant by the cell cycle?

Last Answer : •The continuity of life is based on the reproduction of cells, or cell division

During mechanism of action of insulin, protein kinase C is activated by

Description : During mechanism of action of insulin, protein kinase C is activated by

Last Answer : During mechanism of action of insulin, protein kinase C is activated by A. `PIP_2` B. `IP_3` C. `DG ` D. `Ca^(2+)`

Activated phospholipase C acts on (A) Phosphatidyl inositol-4, 5-biphosphate (B) Inositol-1, 4, 5-triphosphate (C) Protein kinase C (D) Pl-3 kinase

Description : Activated phospholipase C acts on (A) Phosphatidyl inositol-4, 5-biphosphate (B) Inositol-1, 4, 5-triphosphate (C) Protein kinase C (D) Pl-3 kinase

Last Answer : Answer : A

The protein IRS-1 is phosphorylated by (A) Protein kinase A (B) Protein kinase C (C) Tyrosine kinase activity of insulin receptor (D) Tyrosine kinase activity of IGF-1 receptor

Description : The protein IRS-1 is phosphorylated by (A) Protein kinase A (B) Protein kinase C (C) Tyrosine kinase activity of insulin receptor (D) Tyrosine kinase activity of IGF-1 receptor

Last Answer : Answer : B

Vasoconstrictor effect of ADH is mediated by (A) cAMP (B) cGMP (C) Protein kinase C (D) Angiotensin II

Description : Vasoconstrictor effect of ADH is mediated by (A) cAMP (B) cGMP (C) Protein kinase C (D) Angiotensin II

Last Answer : Answer : C

All the following statements about epidermal growth factor are true except (A) It is a protein (B) It possess quaternary structure (C) Its receptor is made up of a single polypeptide chain (D) Its receptor possesses tyrosine kinase domain

Description : All the following statements about epidermal growth factor are true except (A) It is a protein (B) It possess quaternary structure (C) Its receptor is made up of a single polypeptide chain (D) Its receptor possesses tyrosine kinase domain

Last Answer : Answer : B

Protein kinase C is activated by (A) Cyclic AMP (B) Cyclic GMP (C) Diacyl glycerol (D) Inositol triphosphate

Description : Protein kinase C is activated by (A) Cyclic AMP (B) Cyclic GMP (C) Diacyl glycerol (D) Inositol triphosphate

Last Answer : Answer : C

Insulin decreases the activity of (A) cAMP dependent protein kinase (B) HMG CoA-reductas (C) Phosphodiesterase (D) Acetyl CoA-carboxylase

Description : Insulin decreases the activity of (A) cAMP dependent protein kinase (B) HMG CoA-reductas (C) Phosphodiesterase (D) Acetyl CoA-carboxylase

Last Answer : Answer : A

Cyclic AMP binds to (A) Catalytic subunits of protein kinase (B) Regulatory subunits of protein kinase (C) Catalytic subunits of phosphorylase kinase (D) Regulatory subunits of phosphorylase kinase

Description : Cyclic AMP binds to (A) Catalytic subunits of protein kinase (B) Regulatory subunits of protein kinase (C) Catalytic subunits of phosphorylase kinase (D) Regulatory subunits of phosphorylase kinase

Last Answer : Answer : B

Covalent modification of an enzyme generally requires a (A) Hormone (B) cAMP (C) Protein kinase (D) All of these

Description : Covalent modification of an enzyme generally requires a (A) Hormone (B) cAMP (C) Protein kinase (D) All of these

Last Answer : Answer : D

Adipose tissue lacks (A) Hormone-sensitive lipase (B) Glycerol kinase (C) cAMP-dependent protein kinase (D) Glycerol-3-phosphate dehydrogenase

Description : Adipose tissue lacks (A) Hormone-sensitive lipase (B) Glycerol kinase (C) cAMP-dependent protein kinase (D) Glycerol-3-phosphate dehydrogenase

Last Answer : Answer : B

One of the following enzymes does not change glycogen synthase a to b. (A) Glycogen synthase kinases 3, 4, 5 (B) Ca2+ calmodulin phosphorylase kinase (C) Ca2+ calmodulin dependent protein kinase (D) Glycogen phosphorylase a

Description : One of the following enzymes does not change glycogen synthase a to b. (A) Glycogen synthase kinases 3, 4, 5 (B) Ca2+ calmodulin phosphorylase kinase (C) Ca2+ calmodulin dependent protein kinase (D) Glycogen phosphorylase a

Last Answer : D

The best understood intracellular messenger is cyclic AMP (cAMP). Which of the following statement(s) concerning this intracellular messenger is/are correct? a. Intracellular cyclic AMP is constantly degraded by a specific enzyme, cAMP phosphodiesterase b. Most of the actions of cAMP are mediated by activation of protein kinase A c. Intracellular levels of cAMP are relatively stable and change solely in response to activation of adenylate cyclase d. cAMP is the only cyclic nucleotide active as an intracellular messenger

Description : The best understood intracellular messenger is cyclic AMP (cAMP). Which of the following statement(s) concerning this intracellular messenger is/are correct? a. Intracellular cyclic AMP is constantly ... of adenylate cyclase d. cAMP is the only cyclic nucleotide active as an intracellular messenger

Last Answer : Answer: a, b The prototypic intracellular messenger is cAMP. To function as a mediator, the concentration of cAMP must change rapidly. In resting cells, cAMP is continuously being degraded by ... produce cGMP. Intracellular calcium ions also serve as second messengers in a large number of cells

Which of the following statement(s) is/are true concerning cell membrane receptors? a. The largest family of cell surface receptors are the G-protein-linked receptors b. Activities of the G-protein involve binding and hydrolysis of ATP c. The G protein receptor generates an intracellular messenger commonly through the use adenylate cyclase d. Tyrosine kinase receptors are considered G-protein-linked receptors

Description : Which of the following statement(s) is/are true concerning cell membrane receptors? a. The largest family of cell surface receptors are the G-protein-linked receptors b. Activities of the ... through the use adenylate cyclase d. Tyrosine kinase receptors are considered G-protein-linked receptors

Last Answer : Answer: a, c All water-soluble regulatory molecules bind to the cell surface receptor proteins. Binding of the appropriate ligand evokes an intracellular signal which usually regulates ... are adenylate cyclase, which converts ATP to cAMP, and the polyphosphoinositide-specific phospholipase C

With regard to membrane receptors for hormones: a. they are often glycoproteins b. they are important for hormones made up of steroid c. those for insulin exhibit an intrinsic protein kinase activity d. glucagon uses calcium as a second messenger

Description : With regard to membrane receptors for hormones: a. they are often glycoproteins b. they are important for hormones made up of steroid c. those for insulin exhibit an intrinsic protein kinase activity d. glucagon uses calcium as a second messenger

Last Answer : they are often glycoproteins

The antiviral action of amantadine is exerted through: A. Interaction with the viral M2 protein B. Interaction with a virus directed thymidine kinase C. Inhibition of a viral protease enzyme D. Inhibition of viral RNA mediated DNA synthesi

Description : The antiviral action of amantadine is exerted through: A. Interaction with the viral M2 protein B. Interaction with a virus directed thymidine kinase C. Inhibition of a viral protease enzyme D. Inhibition of viral RNA mediated DNA synthesi

Last Answer : A. Interaction with the viral M2 protein

The insulin receptor is a: A. Ion channel regulating receptor B. Tyrosine protein kinase receptor C. G-protein coupled receptor D. None of the above

Description : The insulin receptor is a: A. Ion channel regulating receptor B. Tyrosine protein kinase receptor C. G-protein coupled receptor D. None of the above

Last Answer : B. Tyrosine protein kinase receptor

Agonist induced autophosphorylation, internalization and down regulation is a distinctive feature of: A. G-protein coupled receptors B. Intrinsic ion channel containing receptors C. Tyrosine protein kinase receptors D. Receptors regulating gene expression

Description : Agonist induced autophosphorylation, internalization and down regulation is a distinctive feature of: A. G-protein coupled receptors B. Intrinsic ion channel containing receptors C. Tyrosine protein kinase receptors D. Receptors regulating gene expression

Last Answer : C. Tyrosine protein kinase receptors

The following receptor type has 7 helical membrane spanning amino acid segments with 3 extracellular and 3 intracellular loops: A. Tyrosine protein kinase receptor B. Gene expression regulating receptor C. Intrinsic ion channel containing receptor D. G protein coupled receptor

Description : Receptors perform the following function/functions: A. Ligand recognition B. Signal transduction C. Both ligand recognition and signal transduction D. Disposal of agonists and antagonists

Last Answer : D. Disposal of agonists and antagonists

Agonist induced autophosphorylation, internalization and down regulation is a distinctive feature of: A. G-protein coupled receptors B. Intrinsic ion channel containing receptors C. Tyrosine protein kinase receptors D. Receptors regulating gene expression

Description : Agonist induced autophosphorylation, internalization and down regulation is a distinctive feature of: A. G-protein coupled receptors B. Intrinsic ion channel containing receptors C. Tyrosine protein kinase receptors D. Receptors regulating gene expression

Last Answer : C. Tyrosine protein kinase receptors

The following receptor type has 7 helical membrane spanning amino acid segments with 3 extracellular and 3 intracellular loops: A. Tyrosine protein kinase receptor B. Gene expression regulating receptor C. Intrinsic ion channel containing receptor D. G protein coupled receptor

Description : The following receptor type has 7 helical membrane spanning amino acid segments with 3 extracellular and 3 intracellular loops: A. Tyrosine protein kinase receptor B. Gene expression regulating receptor C. Intrinsic ion channel containing receptor D. G protein coupled receptor

Last Answer : D. G protein coupled receptor

Pyruvate kinase deficiency?

Description : Pyruvate kinase deficiency?

Last Answer : DefinitionPyruvate kinase deficiency is an inherited lack of the enzyme pyruvate kinase, which is used by red blood cells. Without this enzyme, red blood cells break down too easily, resulting in ... However, certain populations, such as the Amish, are somewhat more likely to develop the conditi

cAMD is destroyed by (A) Adenylate cyclase (B) Phosphodiesterase (C) Synthetase phosphatase (D) Synthetase kinase

Description : cAMD is destroyed by (A) Adenylate cyclase (B) Phosphodiesterase (C) Synthetase phosphatase (D) Synthetase kinase

Last Answer : Answer : B

Adenosine kinase can salvage (A) Adenosine (B) Adenosine and deoxyadenosine (C) Adenosine and guanosine (D) Adenine and adenosine

Description : Adenosine kinase can salvage (A) Adenosine (B) Adenosine and deoxyadenosine (C) Adenosine and guanosine (D) Adenine and adenosine

Last Answer : Answer : B

Deoxycytidine kinase can salvage (A) Adenosine (B) Adenosine and deoxyadenosine (C) Adenosine and guanosine (D) Adenine and adenosine

Description : Deoxycytidine kinase can salvage (A) Adenosine (B) Adenosine and deoxyadenosine (C) Adenosine and guanosine (D) Adenine and adenosine

Last Answer : Answer : D

An enzyme of pyrimidine nucleotides biosynthesis regulated at the genetic level by apparently coordinate repression and derepression is (A) Carbamoyl phosphate synthetase (B) Dihydroorotate dehydrogenase (C) Thymidine kinase (D) Deoxycytidine kinase

Description : An enzyme of pyrimidine nucleotides biosynthesis regulated at the genetic level by apparently coordinate repression and derepression is (A) Carbamoyl phosphate synthetase (B) Dihydroorotate dehydrogenase (C) Thymidine kinase (D) Deoxycytidine kinase

Last Answer : Answer : A

Phosphorylation of adenosine to AMP is catalysed by (A) Adenosine kinase (B) Deoxycytidine kinase (C) Adenylosuccinase (D) Adenylosuccinate synthetase

Description : Phosphorylation of adenosine to AMP is catalysed by (A) Adenosine kinase (B) Deoxycytidine kinase (C) Adenylosuccinase (D) Adenylosuccinate synthetase

Last Answer : Answer : A

Activation of IRS-1, PI-3 kinase and GRB2 is brought about by (A) Glucagon (B) Insulin (C) Prolactin (D) IGF-2

Description : Activation of IRS-1, PI-3 kinase and GRB2 is brought about by (A) Glucagon (B) Insulin (C) Prolactin (D) IGF-2

Last Answer : Answer : B

Binding of insulin to its receptor activates (A) Adenylate cyclase (B) Guanylate cyclase (C) Phospholipase C (D) Tyrosine kinase

Description : Binding of insulin to its receptor activates (A) Adenylate cyclase (B) Guanylate cyclase (C) Phospholipase C (D) Tyrosine kinase

Last Answer : Answer : D