Description : The process of breakdown of glycogen to glucose in the liver and pyruvate and lacate in the muscle is known as (A) Glyogenesis (B) Glycogenolysis (C) Gluconeogenesis (D) Cellular degradation
Last Answer : Answer : B
Description : The synthesis of glucose from pyruvate by gluconeogenesis (A) Requires the participation of biotin (B) Occurs exclusively in the cytosol (C) Is inhibited by elevated level of insulin (D) Requires oxidation/reduction of FAD
Last Answer : A
Description : Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct
Last Answer : D. Both A and B are correct
Description : Metformin acts by: A. Releasing insulin from pancreas B. Suppressing gluconeogenesis and glucose output from liver
Last Answer : B. Suppressing gluconeogenesis and glucose output from liver
Description : Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt
Last Answer : Answer : C
Description : Insulin increases (A) Glycogenesis (B) Gluconeogenesis (C) Lipolysis (D) Blood glucose
Last Answer : Answer : A
Description : Glucagon (A) Increases protein synthesis (B) Inhibits lipolysis in adipocytes (C) Increases gluconeogenesis in liver (D) Stimulates muscle glycogenolysis
Description : Gluconeogenesis does not occur in (A) Brain (B) Kidneys (C) Muscles (D) Liver
Description : The sites for gluconeogenesis are (A) Liver and kidney (B) Skin and pancreas (C) Lung and brain (D) Intestine and lens of eye
Description : Gluconeogenesis is increased in the following condition: (A) Diabetes insipidus (B) Diabetes Mellitus (C) Hypothyroidism (D) Liver diseases
Last Answer : B
Description : Which one of the following statements is incorrect? (A) Insulin increases glucose phosphorylation (B) Insulin increases glycolysis (C) Insulin augments HMP shunt (D) Insulin promotes gluconeogenesis
Last Answer : Answer : D
Description : Insulin decreases (A) Glycogenesis (B) Glyolysis (C) Gluconeogenesis (D) Tubular reabsorption of glucose
Description : Growth hormone causes hyperglycemia. It is a result of (A) Decreased peripheral utilization of glucose (B) Decreased hepatic production via gluconeogenesis (C) Increased glycolysis in muscle (D) Decrersed lipolysis
Description : The glycerol for fatty acid esterification in adipocytes is (A) For the most part, derived from glucose (B) Obtained primarily from phosphorylation of glycerol by glycerol kinase (C) Formed from gluconeogenesis (D) Formed from glycogenolysis ENZYMES 153
Description : Ketosis reflects (A) Increased hepatic glucose liberation (B) Increased fatty acid oxidation (C) Increased carbohydrate utilisation (D) Incresed gluconeogenesis
Description : Phlorizin inhibits (A) Renal tubular reabsorption of glucose (B) Glycolysis (C) Gluconeogenesis (D) Glycogenolysis
Description : Which of the following reactions is unique to gluconeogenesis? (A) Lactate Pyruvate (B) Phosphoenol pyruvate pyruvate (C) Oxaloacetate phosphoenol pyruvate (D) Glucose-6-phosphate Fructose-6-phosphate
Last Answer : C
Description : Synthesis of Glucose from amino acids is termed as (A) Glycolysis (B) Gluconeogenesis (C) Glycogenesis (D) Lipogenesis
Description : The 4 rate limiting enzymes of gluconeogenesis are (A) Glucokinase, Pyruvate carboxylae phosphoenol pyruvate carboxykinase and glucose-6-phosphatase (B) Pyruvate carboxylase, phosphoenol ... fructokinase, pyruvate carboxylase, phosphoenol pyruvate carboxykinase and fructose 1, 6 diphosphatase
Description : The conversion of alanine to glucose is termed (A) Glycolysis (B) Oxidative decarboxylation (C) Specific dynamic action (D) Gluconeogenesis
Last Answer : D
Description : Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate
Description : Non-protein nitrogenous substances in blood are raised in (A) Starvation (B) Liver damage (C) Renal failure (D) All of these
Description : The following is true about gluconeogenesis: a. it occurs in liver b. it occurs in kidney c. it occurs in adipose tissue d. it is inhibited by glucagon
Last Answer : it occurs in liver
Description : Glucagon: a. is secreted by beta-islet cell of pancreas b. is a polypeptide hormone c. has a positive cardiac inotropic effect d. causes gluconeogenesis in the liver e. causes glycogenolysis in the liver
Last Answer : is a polypeptide hormone
Description : A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic ... in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis
Last Answer : Answer: a, c One of the earliest consequence of a surgical procedure is the rise in levels of circulating cortisol that occur in response to a sudden outpouring of ACTH ... hepatic glucose production, and, with other hormones (epinephrine and glucocorticoids), gluconeogenesis is maintained
Description : The hormonal alterations that follow operation and injury favor accelerated gluconeogenesis. This new glucose is consumed by which of the following tissues? A. Central nervous system. B. Skeletal muscle. C. Bone. D. Kidney. E. Tissue in the healing wound.
Last Answer : Answer: ADE DISCUSSION: Glucose is produced in increased amounts to satisfy the fuel requirements of the healing wound. In addition, nerve tissue and the renal medulla also utilize this substrate. Skeletal muscle primarily utilizes fatty acids, and bone utilizes mineral substrate
Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin
Description : Lipogenesis in body starts when (a) Glucose combines with glycerol (b) Glycogen depots of muscle and liver are occupied (c) Glycogen depots of muscle and liver are scanty (d) Blood sugar level is high
Last Answer : (b) Glycogen depots of muscle and liver are occupied
Description : In the normal resting state of human most of the blood glucose burnt as fuel is consumed by (A) Liver (B) Brain (C) Adipose tissue (D) Muscles
Description : In the normal resting state of humans, most of the blood glucose burned as fuel is consumed by (A) Liver (B) Adipose tissue (C) Muscle (D) Brain
Description : At low blood glucose concentration, brain but not liver will take up glucose. It is due to the (A) Low Km of hexokinase (B) Low Km of glucokinase (C) Specificity of glucokinase (D) Blood brain barrier
Description : The normal resting state of humans, most of the blood glucose burnt as “fuel” is consumed by (A) Liver (B) Brain (C) Kidneys (D) Adipose tissue
Description : The blood sugar raising action of the hormones of suprarenal cortex is due to (A) Gluconeogenesis (B) Glycogenolysis (C) Glucagon-like activity (D) Due to inhibition of glomerular filtration
Description : The hydrolysis of Glucose-6-phosphate is catalysed by a specific phosphatase which is found only in (A) Liver, intestines and kidneys (B) Brain, spleen and adrenals (C) Striated muscle (D) Plasma
Description : Conversion of glucose to glucose-6- phosphate in human liver is by (A) Hexokinase only (B) Glucokinase only (C) Hexokinase and glucokinase (D) Glucose-6-phosphate dehydrogenase
Description : An essential agent for converting glucose to glycogen in liver is (A) Latic acid (B) GTP (C) UTP (D) Pyruvic acid
Description : Which of the following organ prefers fructose to glucose (A) Liver (B) Testes (C) Pancreas (D) Heart
Description : Hyper insulinism can cause coma since (A) The chief nutrient for the brain is glucose (B) The chief nutrient for the heart is glucose (C) The glucostatic role of the liver is damaged (D) The kidneys are damaged
Description : Insulin is required for the active uptake of glucose by most of the cells except (A) Muscle cells (B) Renal tubular cells (C) Adipocytes (D) Liver cells
Description : Glucose-1-phosphate liberated from glycogen cannot be converted into free glucose in (A) Liver (B) Kidneys (C) Muscles (D) Brain
Description : Galactose is readily converted to glucose in (A) Liver (B) Intestine (C) Kidney (D) Adipose tissue
Description : The number of ATP molecules required to convert 2 molecules of lactate into glucose in mammalian liver is (A) 2 (B) 4 (C) 5 (D) 6
Description : The enzyme glucose 6-phosphatase is present in (A) Liver (B) Muscle (C) Adipose tissue (D) Brain
Description : Von Gierke’s disease is characterized by the deficiency of (A) Glucose-6-phosphatase (B) α -1→ 4 Glucosidase (C) 1→ 6 Glucosidase (D) Liver phosphorylase
Description : The enzyme glucose-6-phosphatase which catalyses the conversion of glucose 6-phosphate to glucose is not found in (A) Liver (B) Muscle (C) Intestine (D) Kidney
Description : The hydrolysis of glucose-6-PO4 is catalyzed by a phosphatase that is not found in which of the following? (A) Liver (B) Kidney (C) Muscle (D) Small intestine
Description : Impaired galactose tolerance test suggests (A) Defect in glucose utilisation (B) Liver cell injury (C) Renal defect (D) Muscle injury
Description : An essential for converting Glucose to Glycogen in Liver is (A) Lactic acid (B) GTP (C) CTP (D) UTP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 19
Description : The hydrolysis of Glucose-6-P is catalysed by a phosphatase that is not formed in which of the following? (A) Liver (B) Kidney (C) Muscle (D) Small intestine
Description : Cori’s cycle transfers (A) Glucose from muscles to liver (B) Lactate from muscles to liver (C) Lactate from liver to muscles (D) Pyruvate from liver to muscles