Description : Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct
Last Answer : D. Both A and B are correct
Description : Glucagon release from pancreas is stimulated by: A. High blood glucose level B. Insulin C. Somatostatin D. Adrenaline
Last Answer : D. Adrenaline
Description : Sulfonylurea hypoglycaemics act by: A. Reducing intestinal absorption of glucose B. Increasing insulin secretion from pancreas C. Reversing down-regulation of insulin receptors D. Both ‘B’ and ‘C’ are correct
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : The 1st phase of insulin release from pancreatic β cells is augmented by: A. Glibenclamide B. Metformin C. Nateglinide D. Both 'A' and 'C'
Last Answer : C. Nateglinide
Description : Glucose entry into the cells of the following organ/ tissue is highly dependent on the presence of insulin: A. Brain B. Liver C. Adipose tissue D. Kidney tubules
Last Answer : C. Adipose tissue
Description : Action of Insulin does not include the following: A. Facilitation of glucose transport into cells B. Facilitation of glycogen synthesis by liver C. Facilitation of neoglucogenesis by liver D. Inhibition of lipolysis in adipose tissue
Last Answer : . Facilitation of neoglucogenesis by liver
Description : The sites for gluconeogenesis are (A) Liver and kidney (B) Skin and pancreas (C) Lung and brain (D) Intestine and lens of eye
Last Answer : Answer : A
Description : Glucagon: a. is secreted by beta-islet cell of pancreas b. is a polypeptide hormone c. has a positive cardiac inotropic effect d. causes gluconeogenesis in the liver e. causes glycogenolysis in the liver
Last Answer : is a polypeptide hormone
Description : Select the correct statement. (a) Glucocorticoids stimulate gluconeogenesis. (b) Glucagon is associated with hypoglycemia. (c) Insulin acts on pancreatic cells and adipocytes. (d) Insulin is associated with hyperglycemia
Last Answer : (a) Glucocorticoids stimulate gluconeogenesis.
Description : Guargum limits post-prandial glycaemia by: A. Inhibiting intestinal brush border α-glucosidases B. Slowing carbohydrate absorption from intestine C. Releasing incretins from the intestine D. Promoting uptake of glucose into skeletal muscles
Last Answer : B. Slowing carbohydrate absorption from intestin
Description : Which one of the following statements is incorrect? (A) Insulin increases glucose phosphorylation (B) Insulin increases glycolysis (C) Insulin augments HMP shunt (D) Insulin promotes gluconeogenesis
Last Answer : Answer : D
Description : Insulin increases (A) Glycogenesis (B) Gluconeogenesis (C) Lipolysis (D) Blood glucose
Description : Insulin decreases (A) Glycogenesis (B) Glyolysis (C) Gluconeogenesis (D) Tubular reabsorption of glucose
Last Answer : Answer : C
Description : The synthesis of glucose from pyruvate by gluconeogenesis (A) Requires the participation of biotin (B) Occurs exclusively in the cytosol (C) Is inhibited by elevated level of insulin (D) Requires oxidation/reduction of FAD
Last Answer : A
Description : A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic ... in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis
Last Answer : Answer: a, c One of the earliest consequence of a surgical procedure is the rise in levels of circulating cortisol that occur in response to a sudden outpouring of ACTH ... hepatic glucose production, and, with other hormones (epinephrine and glucocorticoids), gluconeogenesis is maintained
Description : he following is true of nifedipine except: A. It can aggravate urine voiding difficulty in elderly males with prostatic hypertrophy B. It promotes Na+ retention by a renal tubular action to ... release from pancreas D. At high doses it can paradoxically increase the frequency of angina pectori
Last Answer : B. It promotes Na+ retention by a renal tubular action to cause ankle oedema as side effect
Description : Human insulins are obtained by the following sources/methods except: A. Cadaver pancreas B. Proinsulin recombinant bacterial C. Precursor yeast recombinant D. Enzyme modification of pork insulin
Last Answer : . Cadaver pancreas
Description : Choose the correct statement about long acting calcium channel blocking drugs as antihypertensives: A. They are the most effective drugs in suppressing hypertensive left ventricular hypertrophy B. They ... more than β blockers D. They have no beneficial effect in hypertensive/diabetic nephropath
Last Answer : B. They are as effective as diuretics or β blockers in reducing cardiovascular/total mortality
Description : Potassium therapy tends to counteract the cardiac toxicity of digitalis by: A. Reducing the affinity of sarcolemal Na+ K+ATPase for digitalis B. Suppressing ectopic automaticity enhanced by digitalis C. Promoting A-V conduction D. Both 'A' and 'B' are correct
Last Answer : D. Both 'A' and 'B' are correct
Description : The preferred drug for suppressing febrile convulsions is: A. Intramuscular phenobarbitone B. Intravenous phenytoin C. Rectal diazepam D. Oral sodium valproate
Last Answer : C. Rectal diazepam
Description : Dantrolene sodium reduces skeletal muscle tone by: A. Reducing acetylcholine release from motor nerve endings B. Suppressing spinal polysynaptic reflexes C. Inhibiting the generation of muscle action potential D. Reducing Ca2+ release from sarcoplasmic reticulum in the muscle fibre
Last Answer : D. Reducing Ca2+ release from sarcoplasmic reticulum in the muscle fibre
Description : The process of breakdown of glycogen to glucose in the liver and pyruvate and lacate in the muscle is known as (A) Glyogenesis (B) Glycogenolysis (C) Gluconeogenesis (D) Cellular degradation
Last Answer : Answer : B
Description : Blood glucose level can be raised by gluconeogenesis only by liver, why?
Last Answer : Glucose-6-phosphatase is present only in liver.
Description : he following antidiabetic drug inhibits intestinal brush border α-glucosidase enzymes: A. Acarbose B. Pioglitazone C. Metformin D. Guargum
Last Answer : A. Acarbose
Description : Metformin causes little lowering of blood sugar level in: A. Nondiabetics B. Obese diabetics C. Type 2 diabetics D. Diabetics not responding to sulfonylureas
Last Answer : A. Nondiabetics
Description : Metformin is preferred over phenformin because: A. It is more potent B. It is less liable to cause lactic acidosis C. It does not interfere with vitamin B12 absorption D. It is not contraindicated in patients with kidney disease
Last Answer : B. It is less liable to cause lactic acidosis
Description : Insulin like growth hormones are produced by (A) Hypophysis (B) Liver (C) Pancreas (D) Thyroid
Description : Which organ of human body secretes Insulin? (1) Pancreas (2) Kidney (3) Gall bladder (4) Liver
Last Answer : (1) Pancreas Explanation: Insulin is a hormone secreted by the pancreas that is important for metabolism and utilization of energy from the ingested nutrients - especially glucose. It keeps our ... ). The pancreas is a glandular organ in the digestive system and endocrine system of vertebrates.
Description : Which of the following organs of the body produces insulin? a) liver b) stomach c) pancreas d) small intestine
Last Answer : ANSWER: C -- PANCREAS
Last Answer : Pancreas
Description : Which is NOT a correct association of tissues and hormones or functions? A) adipose tissue--leptin to regulate a feeling of fullness B) thymus--use of iodine to make thyroxine for ... insulin for regulation of blood glucose levels E) pancreas--glucagon for regulation of blood glucose levels
Last Answer : B) thymus--use of iodine to make thyroxine for regulation of body growth
Description : Which of the following statements is TRUE of insulin? Is it: a) secreted by the pancreas b) a protein c) involved in the metabolism of glucose d) all of the above
Last Answer : ANSWER: D -- ALL OF THE ABOVE
Description : Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above
Last Answer : D. All of the above
Description : Which of the following is not a sulfonylurea but acts by analogous mechanism to bring about quick and brief insulin release that is useful for normalizing meal time glycaemic excursions in type 2 diabetes mellitus: A. Glimepiride B. Miglitol C. Repaglinide D. Rosiglitazone
Last Answer : C. Repaglinide
Description : Long-term thiazide therapy can cause hyperglycaemia by: A. Reducing insulin release B. Interfering with glucose utilization in tissues C. Increasing sympathetic activity D. Increasing corticosteroid secretion
Last Answer : A. Reducing insulin release
Description : Diazoxide is an effective hypotensive, but is not used in the long-term treatment of hypertension because: A. It impairs glucose tolerance by inhibiting insulin release B. It inhibits uric acid ... causes marked Na+ and water retention leading to development of tolerance D. All of the above
Description : Select the drug which tends to reverse insulin resistance by increasing cellular glucose transporters: A. Glibenclamide B. Rosiglitazone C. Acarbose D. Prednisolone
Last Answer : B. Rosiglitazone
Description : Which of the following is true of acarbose: A. It reduces absorption of glucose from intestines B. It produces hypoglycaemia in normal as well as diabetic subjects C. It limits postprandial hyperglycaemia in diabetics D. It raises circulating insulin levels
Last Answer : C. It limits postprandial hyperglycaemia in diabetics
Description : Choose the correct statement(s) about actions of insulin: A. It favours translocation of glucose transporters from intracellular site to the plasma membrane B. It enhances transcription of lipoprotein ... vascular endothelium C. It increases production of the enzyme glucokinase D. All of the above
Description : Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization
Last Answer : D. Inhibiting peripheral glucose utilization
Description : Which of the following organ prefers fructose to glucose (A) Liver (B) Testes (C) Pancreas (D) Heart
Description : Choose the correct statement about methenamine (hexamine): A. It acts by getting converted to mandelic acid in the urinary tract B. It releases formaldehyde in acidic urine which inturn kills ... acute urinary tract infections D. It is the preferred urinary antiseptic in patients with liver disease
Last Answer : B. It releases formaldehyde in acidic urine which inturn kills bacteria
Description : Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers ... 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes
Last Answer : B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus
Description : In patients of hepatic cirrhosis: A. The extent of change in pharmacokinetics of drugs can be predicted from the values of liver function tests B. High doses of furosemide can be safely used C. Metformin is the preferred oral hypoglycaemic D. Disposition of atenolol is not significantly affected
Last Answer : D. Disposition of atenolol is not significantly affected
Description : The hypothalamic-releasing hormones directly control the A) adrenal cortex. B) thyroid. C) anterior pituitary. D) posterior pituitary. E) pancreas.
Last Answer : C) anterior pituitary.
Description : Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and utilisation. (a) Insulin (b) Glucagon (c) Secretin (d) Gastrin
Last Answer : (a) Insulin
Description : Angiotensin III is equipotent to angiotensin II in: A. Releasing aldosterone from adrenal cortex B. Promoting Na+ and water reabsorption by direct intrarenal action C. Causing vasoconstriction D. Contracting intestinal smooth muscle
Last Answer : A. Releasing aldosterone from adrenal cortex
Description : Angiotensin II causes rise in blood pressure by: A. Direct vasoconstriction B. Releasing adrenaline from adrenal medulla C. Increasing central sympathetic tone D. All of the above