Description : Which one of the following pairs is incorrectly matched? (a) Glucagon – Beta cells (source) (b) Somatostatin – Delta cells (source) (c) Corpus luteum – Relaxin (secretion) (d) Insulin – Diabetes mellitus (disease
Last Answer : (a) Glucagon – Beta cells (source)
Description : The absorption of glucose in the digestive tract (A) Occurs in the small intestine (B) Is stimulated by the hormone Glucagon (C) Occurs more rapidly than the absorption of any other sugar (D) Is impaired in cases of diabetes mellitus
Last Answer : A
Description : A 16 year old male with a day history of malaise, weakness and vomiting. He was diagnosed with Insulin dependent diabetes mellitus 3 years prviously. Which ONE of the following supports a diagnosis of ... serum glucose 14 mmol/l 4) Decreased appetite in the past few days 5) Shallow respirations
Last Answer : Answers-2 a-An unusual but recognised feature particularly in children. However does not support a diagnosis of DKA. b-Suggests metabolic acidosis. c-'Normoglycaemic DKA' can occur and a glucose ... anorexia. e-Respiratory compensation leads to rapid deep (Kussmaul's) breathing. (Dr Mike Mulcahy)
Description : Which of the following clinical characteristics is associated with Type 2 diabetes (previously referred to as non-insulin-dependent diabetes mellitus [NIDDM])? a) Can control blood glucose ... islet cell antibodies Individuals with Type 2 diabetes do not demonstrate islet cell antibodies.
Last Answer : a) Can control blood glucose through diet and exercise Oral hypoglycemic agents may improve blood glucose levels if dietary modification and exercise are unsuccessful.
Description : Which of the following statements is NOT true about diabetes mellitus? A) Type II diabetes is much more common than type I. B) Insulin injections are required in both type I and type II ... -sugar diet. E) Symptoms of diabetes include excessive thirst, frequent urination, and glucose in the urine.
Last Answer : B) Insulin injections are required in both type I and type II diabetes.
Description : The following feature disfavours use of oral hypoglycaemics in diabetes mellitus: A. Age at onset of disease over 40 years B. Insulin requirement more than 40 U/day C. Fasting blood sugar level between 100–200 mg/dl D. Associated obesity
Last Answer : B. Insulin requirement more than 40 U/day
Description : The primary stimulus for insulin secretion is increased. (A) Blood level of epinephrine (B) Blood level of glucagon (C) Blood level of glucose (D) Water intake
Last Answer : Answer : C
Description : Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above
Last Answer : D. All of the above
Description : Bence Jones proteins may be excreted in urine of patients suffering from (A) Tuberculosis (B) Diabetes mellitus (C) Multiple myeloma (D) Hyperthyroidism
Description : Which of the following represents the action of insulin? (a) Increases blood glucose level by stimulating glucagon production. (b) Decreases blood glucose levels by forming glycogen. (c) ... promoting cellular uptake of glucose. (d) Increases blood glucose levels by hydrolysis of glycogen.
Last Answer : (b) Decreases blood glucose levels by forming glycogen
Description : Which is NOT a correct association of tissues and hormones or functions? A) adipose tissue--leptin to regulate a feeling of fullness B) thymus--use of iodine to make thyroxine for ... insulin for regulation of blood glucose levels E) pancreas--glucagon for regulation of blood glucose levels
Last Answer : B) thymus--use of iodine to make thyroxine for regulation of body growth
Description : Which hormone will decrease blood glucose levels? A) thyroxin B) aldosterone C) cortisol D) insulin E) glucagon
Last Answer : D) insulin
Description : Glucagon release from pancreas is stimulated by: A. High blood glucose level B. Insulin C. Somatostatin D. Adrenaline
Last Answer : D. Adrenaline
Description : Adrenaline raises blood glucose level by the following actions except: A. Inducing hepatic glycogenolysis B. Inhibiting insulin secretion from pancreatic β cells C. Augmenting glucagon secretion from pancreatic α cells D. Inhibiting peripheral glucose utilization
Last Answer : D. Inhibiting peripheral glucose utilization
Description : An 16-year-old man presents with polyuria and polydipsia. Which of the following may confirm the diagnosis of diabetes mellitus? 1) A random plasma glucose of >7.5 mmol/L 2) A finding of 3+ ketonuria 3) An HbA1c of 7.0% 4) A fasting plasma glucose of 7.5 mmol/L 5) An abnormal glucose tolerance test
Last Answer : Answers-4 The diagnosis is usually relatively easy to confirm in a symptomatic subject. A random glucose of >11.1 mmol/L or a fasting glucose of >7.0 mmol/L would be regarded as ... haemoglobin (HbA1c) is also highly suggestive but not diagnostic. A glucose tolerance test is rarely needed.
Description : A patient of diabetes mellitus excreted glucose in urine even when he was kept in a carhbohydrate-free diet. It is because
Last Answer : A patient of diabetes mellitus excreted glucose in urine even when he was kept in a ... muscles are discharged in blood stream from liver
Description : Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers ... 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes
Last Answer : B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus
Description : Which of the following is not a specific indication for the more expensive monocomponent/human insulins: A. Insulin resistance B. Pregnant diabetic C. Sulfonylurea maintained diabetic posted for surgery D. Type 1 diabetes mellitus
Last Answer : D. Type 1 diabetes mellitus
Description : Diabetes insipidus is caused by deficient secretion of (A) Insulin (B) Glucagon (C) Vasopressin (D) Oxytocin
Description : Hypoglycaemic coma can occur (A) In untreated diabetes mellitus (B) In starvation (C) After overdose of oral hypoglycaemic drugs (D) After overdose of insulin
Last Answer : Answer : D
Description : Diabetes mellitus can occur due to all of the following except (A) Deficient insulin secretion (B) Tumour of β−cells (C) Decrease in number of insulin receptors (D) Formation of insulin antibodies
Last Answer : Answer : B
Description : The rate of HMP shunt reactions is (A) Increased by Insulin (B) Increased in diabetes mellitus (C) Increased by glucagons (D) Increased in starvation
Last Answer : Answer : A
Description : Obesity generally reflects excess intake of energy and is often associated with the development of (A) Nervousness (B) Non-insulin dependent diabetes mellitus (C) Hepatitis (D) Colon cancer
Description : Intensive insulin therapy: A. Prevents the aggressive development of atherosclerosis in diabetic patients. B. Is not associated with unawareness of hypoglycemia. C. Improves peripheral neuropathy. D. ... . E. Is indicated in all patients with non-insulin-dependent diabetes mellitus (NIDDM).
Last Answer : Answer: C DISCUSSION: Intensive insulin therapy is indicated in patients with IDDM who can actively participate in their own management and the attainment of the goals set for ... or prevents progression of these complications; however, better glucose control may improve peripheral neuropathy
Description : Which of the following conditions may be detectable by growth monitoring? 1) Hyperthyroidism 2) Hypothyroidism 3) Pseudohypoparathyroidism 4) XYY Syndrome 5) Insulin dependent diabetes mellitus
Last Answer : Answers-2
Description : The following occur in untreated insulin dependent diabetes mellitus: a. diuresis b. decreased plasma amino acid c. increased plasma fatty acid d. ketonuria
Last Answer : ketonuria
Description : Which one of the following pairs correctly matches a hormone with a disease resulting from its deficiency? (a) Luteinising - Failure of ovulation hormone (b) Insulin - Diabetes insipidus (c) Thyroxine - Tetany (d) Parathyroid - Diabetes mellitus hormone
Last Answer : (a) Luteinising - Failure of ovulation hormone
Description : Match the following hormones with their respective disease. (A) Insulin (i) Addison's disease (B) Thyroxin (ii) Diabetes insipidus (C) Corticoids (iii)Acromegaly (D) Growth hormone (iv) Goitre (v) Diabetes mellitus Select the correct option ... (iii) (c) (ii) (iv) (iii) (i) (d) (v) (iv) (i) (iii)
Last Answer : (d) (v) (iv) (i) (iii
Description : Which of the following clinical characteristics is associated with Type 1 diabetes (previously referred to as insulin-dependent diabetes mellitus [IDDM])? a) Presence of islet cell antibodies ... Requirement for oral hypoglycemic agents Individuals with Type 1 diabetes need insulin to preserve life.
Last Answer : a) Presence of islet cell antibodies Individuals with Type 1 diabetes often have islet cell antibodies.
Description : The present status of oral hypoglycaemics in diabetes mellitus is: A. They are the first choice drug in all cases B. They should be prescribed only if the patient refuses insulin injections C. ... I diabetes mellitus D. They are used first in most uncomplicated mild to moderate type 2 diabetics
Last Answer : D. They are used first in most uncomplicated mild to moderate type 2 diabetics
Description : The thiazolidinediones are mainly used as: A. Sole drug in type 1 diabetes mellitus B. Sole drug in type 2 diabetes mellitus C. Addon drug to a sulfonylurea and/or a biguanide in type 2 diabetes mellitus D. Addon drug to insulin in type 1 ... 18.34 1 8 . 3 4 B 18.35 1 8 . 3 5 D 18.36 1 8 . 3 6 C
Last Answer : C. Addon drug to a sulfonylurea and/or a biguanide in type 2 diabetes mellitus
Description : Which of the following is not a sulfonylurea but acts by analogous mechanism to bring about quick and brief insulin release that is useful for normalizing meal time glycaemic excursions in type 2 diabetes mellitus: A. Glimepiride B. Miglitol C. Repaglinide D. Rosiglitazone
Last Answer : C. Repaglinide
Description : Insulin therapy is required for the following category/ categories of type 2 diabetes mellitus patients: A. Patients with ketoacidosis B. Patients undergoing surgery C. Pregnant diabetic D. All of the above
Description : In a patient of diabetes mellitus maintained on insulin therapy, administration of the following drug can vitiate glycaemia control: A. Prednisolone B. Prazosin C. Paracetamol D. Phenytoin
Last Answer : A. Prednisolone
Description : Which of the following statements is correct? (A) Thyroxine inhibits utilization of glucose (B) Insulin increases utilization of glucose (C) Glucagon promotes muscle glycogenolysis (D) Insulin inhibits lipogenesis from carbohydrates
Description : The harmone acting directly on intestinal mucosa and stimulating glucose absorption is (A) Insulin (B) Glucagon (C) Thyroxine (D) Vasopressin
Description : Which of the following hormone increases the absorption of glucose from G.I.T? (A) Insulin (B) Throid hormones (C) Glucagon (D) FSH
Description : A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic ... in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis
Last Answer : Answer: a, c One of the earliest consequence of a surgical procedure is the rise in levels of circulating cortisol that occur in response to a sudden outpouring of ACTH ... hepatic glucose production, and, with other hormones (epinephrine and glucocorticoids), gluconeogenesis is maintained
Description : Hepatic abnormalities have been noted in adults since the beginning of hyperalimentation. Which of the following statements are true? A. Hepatic steatosis appears to be associated with an overload ... insulin-glucagon ratio are thought to be causative of hepatic steatosis in experimental animals.
Last Answer : Answer: AD DISCUSSION: The most common metabolic complication of TPN in adults is hepatic steatosis. Unlike the hepatic abnormalities in children, which may progress to cholestasis, liver damage, ... glucagon, which is elicited by certain amino acids, results in the mobilization of hepatic lipid
Description : Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and utilisation. (a) Insulin (b) Glucagon (c) Secretin (d) Gastrin
Last Answer : (a) Insulin
Description : Glucose tolerance is decreased in (A) Diabetes mellitus (B) Hypopituitarisme (C) Addison’s disease (D) Hypothyroidism
Description : Glucose tolerance is increased in (A) Diabetes mellitus (B) Adrenalectomy (C) Acromegaly (D) Thyrotoxicosis
Last Answer : B
Description : Renal threshold for glucose is decreased in (A) Diabetes mellitus (B) Insulinoma (C) Renal glycosuria (D) Alimentary glycosuria
Last Answer : C
Description : Which of the following symptoms is NOT characteristic of diabetes mellitus? A) cells unable to take up glucose B) increased breakdown of fats and protein C) frequent urination D) sugar in the urine E) bronzing of the skin
Last Answer : E) bronzing of the skin
Description : Restriction of salt intake is generally recommended in (A) Diabetes mellitus (B) Hypertension (C) Cirrhosis of liver (D) Peptic ulcer
Description : This pancreatic hormone increases the blood-sugar level: (A) Insulin (B) Glucagon (C) Pancreozymin (D) Pancreatic polypeptide
Description : Which hormone causes dilation of blood vessels, increased oxygen consumption and glucogenesis? (a) Glucagon (b) ACTH (c) Insulin (d) Adrenaline
Last Answer : (d) Adrenaline
Description : Given below is an incomplete table on hormones, their source glands and one major effect of each human body. Identify the option representing correct grouping of hormone its gland and ... hormone (b) Placenta Insulin Vasopressin (c) Ovary Insulin Calcitonin (d) Placenta Glucagon Calcitonin
Last Answer : (a) Ovary Glucagon Growth hormone