The thiazolidinediones are mainly used as: A. Sole drug in type 1 diabetes mellitus B. Sole drug in type 2 diabetes mellitus C. Addon drug to a sulfonylurea and/or a biguanide in type 2 diabetes mellitus D. Addon drug to insulin in type 1 diabetes mellitus (p. 250) 18.33 1 8 . 3 3 C 18.34 1 8 . 3 4 B 18.35 1 8 . 3 5 D 18.36 1 8 . 3 6 C

The thiazolidinediones are mainly used as:
A. Sole drug in type 1 diabetes mellitus
B. Sole drug in type 2 diabetes mellitus
C. Addon drug to a sulfonylurea and/or a
biguanide in type 2 diabetes mellitus
D. Addon drug to insulin in type 1 diabetes
mellitus (p. 250)
18.33 1 8 . 3 3 C 18.34 1 8 . 3 4 B 18.35 1 8 . 3 5 D 18.36 1 8 . 3 6 C
by

1 Answer

Answer :

C. Addon drug to a sulfonylurea and/or a
biguanide in type 2 diabetes mellitus
by

Related questions

Which of the following is not a sulfonylurea but acts by analogous mechanism to bring about quick and brief insulin release that is useful for normalizing meal time glycaemic excursions in type 2 diabetes mellitus: A. Glimepiride B. Miglitol C. Repaglinide D. Rosiglitazone

Description : Which of the following is not a sulfonylurea but acts by analogous mechanism to bring about quick and brief insulin release that is useful for normalizing meal time glycaemic excursions in type 2 diabetes mellitus: A. Glimepiride B. Miglitol C. Repaglinide D. Rosiglitazone

Last Answer : C. Repaglinide

Which of the following is not a specific indication for the more expensive monocomponent/human insulins: A. Insulin resistance B. Pregnant diabetic C. Sulfonylurea maintained diabetic posted for surgery D. Type 1 diabetes mellitus

Description : Which of the following is not a specific indication for the more expensive monocomponent/human insulins: A. Insulin resistance B. Pregnant diabetic C. Sulfonylurea maintained diabetic posted for surgery D. Type 1 diabetes mellitus

Last Answer : D. Type 1 diabetes mellitus

The major limitation of the thiazolidinediones in the treatment of type 2 diabetes mellitus is: A. Frequent hypoglycaemic episodes B. Hyperinsulinemia C. Lactic acidosis D. Low hypoglycaemic efficacy in moderate to severe cases

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Last Answer : D. Low hypoglycaemic efficacy in moderate to severe cases

The present status of oral hypoglycaemics in diabetes mellitus is: A. They are the first choice drug in all cases B. They should be prescribed only if the patient refuses insulin injections C. They are used only in type I diabetes mellitus D. They are used first in most uncomplicated mild to moderate type 2 diabetics

Description : The present status of oral hypoglycaemics in diabetes mellitus is: A. They are the first choice drug in all cases B. They should be prescribed only if the patient refuses insulin injections C. ... I diabetes mellitus D. They are used first in most uncomplicated mild to moderate type 2 diabetics

Last Answer : D. They are used first in most uncomplicated mild to moderate type 2 diabetics

1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50'. What number is missing? -Riddles

Description : 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50'. What number is missing? -Riddles

Last Answer : 22

In a patient of diabetes mellitus maintained on insulin therapy, administration of the following drug can vitiate glycaemia control: A. Prednisolone B. Prazosin C. Paracetamol D. Phenytoin

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Choose the correct statement(s) about pioglitazone: A. It acts as an agonist on nuclear paroxisome proliferator receptor γ B. It enhances transcription of insulin responsive genes C. It lowers blood sugar in type 2 diabetes mellitus without causing hyperinsulinemia D. All of the above

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Last Answer : D. All of the above

Insulin therapy is required for the following category/ categories of type 2 diabetes mellitus patients: A. Patients with ketoacidosis B. Patients undergoing surgery C. Pregnant diabetic D. All of the above

Description : Insulin therapy is required for the following category/ categories of type 2 diabetes mellitus patients: A. Patients with ketoacidosis B. Patients undergoing surgery C. Pregnant diabetic D. All of the above

Last Answer : D. All of the above

Insulin therapy is required for the following category/ categories of type 2 diabetes mellitus patients: A. Patients with ketoacidosis B. Patients undergoing surgery C. Pregnant diabetic D. All of the above

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Last Answer : D. All of the above

The following feature disfavours use of oral hypoglycaemics in diabetes mellitus: A. Age at onset of disease over 40 years B. Insulin requirement more than 40 U/day C. Fasting blood sugar level between 100–200 mg/dl D. Associated obesity

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Sulfonylurea hypoglycaemics act by: A. Reducing intestinal absorption of glucose B. Increasing insulin secretion from pancreas C. Reversing down-regulation of insulin receptors D. Both ‘B’ and ‘C’ are correct

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Choose the correct statement about nateglinide: A. It is a long acting oral hypoglycaemic drug B. Taken just before a meal, it limits postprandial hyperglycaemia in type 2 diabetes mellitus C. It lowers blood glucose in both type 1 and type 2 diabetes mellitus D. It acts by opening K+ channels in myocytes and adipocytes

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Which of the following is not likely to be the cause of failure of antimicrobial therapy of an acute infection: A. Improper selection of drug and dose B. Acquisition of resistance during treatment C. Failure to drain the pus D. Uncontrolled diabetes mellitus

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Which of the following drugs can precipitate hypoglycaemia if given to a diabetic controlled with a sulfonylurea drug: A. Phenobarbitone B. Chloramphenicol C. Rifampicin D. Oral contraceptive

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25,?,45,58,73,90,109 a) 33 b) 34 c) 35 d) 38 e) 36

Description : 25,?,45,58,73,90,109 a) 33 b) 34 c) 35 d) 38 e) 36

Last Answer : The series is 3×5+10=25,4×6+10=34,5×7+10=45,6×8+10=58,7×9+10=73,8× 10+10=90,9×11+10=109 Hence missing term=34 Answer: b)

EAN of [Ni(CO)4] complex is? a) 36 b) 33 c) 35 d) 34

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Insert the missing number: 16/32, 15 /33, 17/31, 14/34, ? (A) 19/35 (B) 19/30 (C) 18/35 (D) 18/30

Description : Insert the missing number: 16/32, 15 /33, 17/31, 14/34, ? (A) 19/35 (B) 19/30 (C) 18/35 (D) 18/30

Last Answer : Answer: D 16/32 then 15/33 means -1/+1, 17/31 means +2/-2, 14/34 means -3/+3 next +4/-4 i.e 18/30

Which of the following clinical characteristics is associated with Type 2 diabetes (previously referred to as non-insulin-dependent diabetes mellitus [NIDDM])? a) Can control blood glucose through diet and exercise Oral hypoglycemic agents may improve blood glucose levels if dietary modification and exercise are unsuccessful.

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Which of the following clinical characteristics is associated with Type 1 diabetes (previously referred to as insulin-dependent diabetes mellitus [IDDM])? a) Presence of islet cell antibodies Individuals with Type 1 diabetes often have islet cell antibodies.

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Which of the following statements is NOT true about diabetes mellitus? A) Type II diabetes is much more common than type I. B) Insulin injections are required in both type I and type II diabetes. C) Type I diabetes occurs as a result of destruction of the insulin-producing cells. D) One method of treating type II diabetes is exercise and a low-fat, low-sugar diet. E) Symptoms of diabetes include excessive thirst, frequent urination, and glucose in the urine.

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Prolonged lithium therapy can cause: A. Diabetes mellitus B. Goiter C. Parkinsonism D. Gout

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The duration of action of insulin-zinc suspension (lente insulin) is: A. 2–4 hours B. 8–10 hours C. 20–24 hours D. 30–36 hours

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Which of the following conditions may be detectable by growth monitoring? 1) Hyperthyroidism 2) Hypothyroidism 3) Pseudohypoparathyroidism 4) XYY Syndrome 5) Insulin dependent diabetes mellitus

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Last Answer : Answers-2

A 16 year old male with a day history of malaise, weakness and vomiting. He was diagnosed with Insulin dependent diabetes mellitus 3 years prviously. Which ONE of the following supports a diagnosis of diabetic ketoacidosis: 1) Abdominal pain at onset 2) A serum bicarbonate of 10 mmol/l 3) A serum glucose 14 mmol/l 4) Decreased appetite in the past few days 5) Shallow respirations

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Chlorpropamide is not a preferred sulfonylurea because: A. Hypoglycaemic reaction is more common with it B. Incidence of alcohol intolerance reaction is higher with it C. It can produce cholestatic jaundice D. All of the above

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Last Answer : D. All of the above

The second generation sulfonylurea hypoglycaemics differ from the first generation ones in that they: A. Are more potent B. Are longer acting C. Do not lower blood sugar in nondiabetic subjects D. Are less prone to cause hypoglycaemic reaction

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Dorzolamide is a: A. Topically applied ocular carbonic anhydrase inhibitor B. Second generation sulfonylurea hypoglycaemic C. Topical sulfonamide antibacterial D. Luminal amoebicide

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Dorzolamide is a: A. Topically applied ocular carbonic anhydrase inhibitor B. Second generation sulfonylurea hypoglycaemic C. Topical sulfonamide antibacterial D. Luminal amoebicide

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Last Answer : A. Topically applied ocular carbonic anhydrase inhibitor

Hypoglycaemic coma can occur (A) In untreated diabetes mellitus (B) In starvation (C) After overdose of oral hypoglycaemic drugs (D) After overdose of insulin

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Last Answer : Answer : D

Diabetes mellitus can occur due to all of the following except (A) Deficient insulin secretion (B) Tumour of β−cells (C) Decrease in number of insulin receptors (D) Formation of insulin antibodies

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The rate of HMP shunt reactions is (A) Increased by Insulin (B) Increased in diabetes mellitus (C) Increased by glucagons (D) Increased in starvation

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Obesity generally reflects excess intake of energy and is often associated with the development of (A) Nervousness (B) Non-insulin dependent diabetes mellitus (C) Hepatitis (D) Colon cancer

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Last Answer : Answer : B

Intensive insulin therapy: A. Prevents the aggressive development of atherosclerosis in diabetic patients. B. Is not associated with unawareness of hypoglycemia. C. Improves peripheral neuropathy. D. Improves established retinopathy and nephropathy. E. Is indicated in all patients with non–insulin-dependent diabetes mellitus (NIDDM).

Description : Intensive insulin therapy: A. Prevents the aggressive development of atherosclerosis in diabetic patients. B. Is not associated with unawareness of hypoglycemia. C. Improves peripheral neuropathy. D. ... . E. Is indicated in all patients with non-insulin-dependent diabetes mellitus (NIDDM).

Last Answer : Answer: C DISCUSSION: Intensive insulin therapy is indicated in patients with IDDM who can actively participate in their own management and the attainment of the goals set for ... or prevents progression of these complications; however, better glucose control may improve peripheral neuropathy

A man suffering from diabetes mellitus drinks water more frequently as he has to eliminate from the blood extra (1) glucose (2) insulin (4) glucagon (4) salt

Description : A man suffering from diabetes mellitus drinks water more frequently as he has to eliminate from the blood extra (1) glucose (2) insulin (4) glucagon (4) salt

Last Answer : (1) glucose Explanation: The diabetic person has higher sugar in blood. Glucose is a form of sugar.

The following occur in untreated insulin dependent diabetes mellitus: a. diuresis b. decreased plasma amino acid c. increased plasma fatty acid d. ketonuria

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Last Answer : ketonuria

Which one of the following pairs correctly matches a hormone with a disease resulting from its deficiency? (a) Luteinising - Failure of ovulation hormone (b) Insulin - Diabetes insipidus (c) Thyroxine - Tetany (d) Parathyroid - Diabetes mellitus hormone

Description : Which one of the following pairs correctly matches a hormone with a disease resulting from its deficiency? (a) Luteinising - Failure of ovulation hormone (b) Insulin - Diabetes insipidus (c) Thyroxine - Tetany (d) Parathyroid - Diabetes mellitus hormone

Last Answer : (a) Luteinising - Failure of ovulation hormone

Which one of the following pairs is incorrectly matched? (a) Glucagon – Beta cells (source) (b) Somatostatin – Delta cells (source) (c) Corpus luteum – Relaxin (secretion) (d) Insulin – Diabetes mellitus (disease

Description : Which one of the following pairs is incorrectly matched? (a) Glucagon – Beta cells (source) (b) Somatostatin – Delta cells (source) (c) Corpus luteum – Relaxin (secretion) (d) Insulin – Diabetes mellitus (disease

Last Answer : (a) Glucagon – Beta cells (source)

Match the following hormones with their respective disease. (A) Insulin (i) Addison’s disease (B) Thyroxin (ii) Diabetes insipidus (C) Corticoids (iii)Acromegaly (D) Growth hormone (iv) Goitre (v) Diabetes mellitus Select the correct option. (A) (B) (C) (D) (a) (ii) (iv) (i) (iii) (b) (v) (i) (ii) (iii) (c) (ii) (iv) (iii) (i) (d) (v) (iv) (i) (iii)

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Last Answer : (d) (v) (iv) (i) (iii

In diabetic patients, round the clock tight control of hyperglycaemia achieved by multiple daily insulin injections or insulin pumps: A. Prevents macrovascular disease more effectively B. Is recommended in all type 2 diabetes patients C. Is associated with higher incidence of hypoglycaemic reactions D. Both A and C are correct

Description : In diabetic patients, round the clock tight control of hyperglycaemia achieved by multiple daily insulin injections or insulin pumps: A. Prevents macrovascular disease more effectively B. Is recommended ... Is associated with higher incidence of hypoglycaemic reactions D. Both A and C are correct

Last Answer : D. Both A and C are correct

40 39 32 37 16 ? -8 a) 35 b) 36 c) 33 d) 32 e) 40

Description : 40 39 32 37 16 ? -8 a) 35 b) 36 c) 33 d) 32 e) 40

Last Answer : The series is + (1^2 - 2), – (2^2 + 3), + (3^2 - 4), –(4^2 + 5), ..... Answer: a)

The sum of the ages of the 4 members of Sinha family is 172 years. 8 years ago the ages of the 4 members Nishu, Vicky, Mrs.Sinha and Sinha were in the ratio of 2:3:7:8. After how many years would Nishu be as old as the present age of his mother? a) 33 years b) 35 years c) 36 years d) 37 years e) None of these

Description : The sum of the ages of the 4 members of Sinha family is 172 years. 8 years ago the ages of the 4 members Nishu, Vicky, Mrs.Sinha and Sinha were in the ratio of 2:3:7:8. After how many years would Nishu be ... present age of his mother? a) 33 years b) 35 years c) 36 years d) 37 years e) None of these

Last Answer : Answer: B Let their ages 8 years ago be 2x, 3x, 7x, and 8x. Their ages now 2x+8, 3x+8, 7x+8, 8x+8. According to the question, =2x+8+3x+8+7x+8+8x+8=172 20x+32=172 =>x=140/20=7 Present age of Nishu=2×7+8=22 years Present age of mother=7×7+8=57 years Hence, required years (57-22)=35 years

How much distance was traveled by first train of India? (a) 33 km (b) 36 km (c) 34 km (d) 46 km

Description : How much distance was traveled by first train of India? (a) 33 km (b) 36 km (c) 34 km (d) 46 km

Last Answer : (c) 34 km

Find the root value of 36.1 / 102.4 (1) 61 / 34 (2) 19 / 31 (3) 19 / 32 (4) 19 / 33

Description : Find the root value of 36.1 / 102.4 (1) 61 / 34 (2) 19 / 31 (3) 19 / 32 (4) 19 / 33

Last Answer : (3) 19 / 32

My brother is 3 years elder to me. My father was 28 years of age when my sister was born while my mother was 26 years of age when I was born. If my sister was 4 years of age when my brother was born, then what was the age my father when my brother was born? a) 35 years b) 34 years c) 33 years d) 32 years e) 30 years

Description : My brother is 3 years elder to me. My father was 28 years of age when my sister was born while my mother was 26 years of age when I was born. If my sister was 4 years of age when my brother was born, ... father when my brother was born? a) 35 years b) 34 years c) 33 years d) 32 years e) 30 years

Last Answer : Let my age = x Then My brother's age = x + 3 My mother's age = x + 26 My sister's age = (x + 3) + 4 = x + 7 My Father's age = (x + 7) + 28 = x + 35 => age my father when my brother was born = x + 35 – (x + 3) = 32. Answer: d)

If 20 kg of coarse aggregate is sieved through 80 mm, 40 mm, 20 mm, 10 mm, 4.75 mm, 2.36 mm, 1.18 mm, 600 micron, 300 micron and 150 micron standard sieves and the weights retained are 0 kg, 2 kg, 8 kg, 6 kg, 4 kg respectively, the fineness modulus of the aggregate, is (A) 7.30 (B) 7.35 (C) 7.40 (D) 7.45

Description : If 20 kg of coarse aggregate is sieved through 80 mm, 40 mm, 20 mm, 10 mm, 4.75 mm, 2.36 mm, 1.18 mm, 600 micron, 300 micron and 150 micron standard sieves and the weights retained are 0 kg, 2 kg, 8 kg, ... , the fineness modulus of the aggregate, is (A) 7.30 (B) 7.35 (C) 7.40 (D) 7.45

Last Answer : Answer: Option C

18 years old female weighting 52Kg and 163cm tall. On dental examination erosion of teeth on the most of her lingual surfaces is clearly showing. Dietary history revealed a daily rate of 5000 to 7000 Kcal/day. What is the most probable diagnosis? A. Alcoholism B. Drug abuse C. Bulimia D. Excessive smoking E. Diabetic mellitus type I

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Last Answer : C. Bulimia

The odd numbers from 1 to 45 which are exactly divisible by 3 are arranged in an ascending order. The number at 6 th position is (A) 18 (B) 24 (C) 33 (D) 36

Description : The odd numbers from 1 to 45 which are exactly divisible by 3 are arranged in an ascending order. The number at 6 th position is (A) 18 (B) 24 (C) 33 (D) 36

Last Answer : Answer: C

Select the drug which tends to reverse insulin resistance by increasing cellular glucose transporters: A. Glibenclamide B. Rosiglitazone C. Acarbose D. Prednisolone

Description : Select the drug which tends to reverse insulin resistance by increasing cellular glucose transporters: A. Glibenclamide B. Rosiglitazone C. Acarbose D. Prednisolone

Last Answer : B. Rosiglitazone