Description : The most important mechanism of concurrent acquisition of multidrug resistance among bacteria is: A. Mutation B. Conjugation C. Transduction D. Transformation
Last Answer : B. Conjugation
Description : The most important mechanism of bacterial resistance to an aminoglycoside antibiotic is (a) Plasmid mediated acquisition of aminoglycoside conjugating enzyme (b) Mutational acquisition of aminoglycoside ... affinity of ribosomal protein for the antibiotic (d) Mutational loss of porin channels
Last Answer : Ans: A
Description : Widespread and prolonged used of an antibiotic leads to emergence of drug resistant strains because antibiotics (a) Induce mutation in the bacteria (b) Promote conjugation among bacteria (c) Allow resistant strains to propagate preferentially (d) All of the above
Last Answer : Ans: C
Description : Penicillin resistance in staphylococci is acquired due to A.conjugation B.mutation C.transformation D.transduction
Last Answer : D.transduction
Description : Penicillin resistance in staphylococci is acquired due to A- conjugation B- mutation C- transformation D- transduction
Last Answer : transduction
Description : Which of the following is the cause for drug resistance in tuberculosis? A- Mutation B- Transduction C- Transformation D- Conjugation
Last Answer : Mutation
Description : The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is (a) Decreased permeability into the bacterial cell (b) Acquisition of a plasmid encoded ... bacterial ribosome for chloramphenicol (d) Switching over from ribosomal to mitochondrial protein synthesis
Last Answer : Ans: B
Description : The term used for acquisition of naked DNA from its environment and its incorporation in their genome by a bacterium is A.transformation B.lysogenic conversion C.conjugation D.transduction
Last Answer : A.transformation
Description : The term used for acquisition of naked DNA from its environment and its incorporation in theirgenome by a bacterium is A- transformation B- lysogenic conversion C- conjugation D- .transduction
Last Answer : transformation
Description : The term used for acquisition of naked DNA from its environment and its incorporation in their A- transformation B- lysogenic conversion C- conjugation D- transduction
Description : The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is (a) They chelate Ca2+ ions and alter permeability of bacterial cell membrane (b) They bind to 30S ribosomes ... peptide chain in the bacteria (d) They interfere with DNA mediated RNA synthesis in bacteria
Description : Which one of the following drugs is most likely to be effective against multidrug – resistant strains of M tuberculosis, including those resistant to streptomycin? (a) Amikacin (b) Clarithromycin (c) Gentamicin (d) Meropenem (e) Spectinomycin
Description : Which of the following is NOT a type of horizontal gene transfer between bacterial cells? a. transformation b. conjugation c. transduction d. translation
Last Answer : d. translation
Description : Which one of the following is NOT an example of genetic recombination? a. Conjugation b. Binary fission c. Transduction d. Transformation
Last Answer : c. Transduction
Description : Which of the following is NOT a mode of genetic exchange within a bacterial population? a) conjugation b) transduction c) transformation d) translation
Last Answer : ANSWER: D -- TRANSLATION
Description : Penicillins interfere with bacterial cell wall synthesis by (a) Inhibiting synthesis of N-acetyl muramic acid pentapeptide (b) Inhibiting conjugation between N-acetyl muramic acid and N-acetyl ... link the peptidoglycan residues (d) Counterfeiting for D-alanine in the bacterial cell wall
Description : The primary mechanism underlying the resistance of gram-positive organisms to macrolide antibiotics is (a) Methylation of binding sites on the 50S ribosomal subunit (b) Formation of ... ) Formation of drug-inactivating acetyltranferases (e) Decreased drug permeability of the cytoplasmic membrane
Description : The most common mechanism of development of resistance to fluoroquinolones is: A. Chromosomal mutation altering affinity of target site B. Plasmid transfer C. Acquisition of drug destroying enzyme D. Acquisition of alternative metabolic pathway
Last Answer : A. Chromosomal mutation altering affinity of target site
Description : All of the following factors may increase the risk of nephrotoxicity from gentamicin therapy except (a) age over 70 years (b) prolonged courses of gentamicin therapy (c) concurrent amphotericin B therapy (d) trough gentamicin levels below 2 mg/ml (e) concurrent cisplatin therapy
Last Answer : Ans: D
Description : Widespread and prolonged use of an antibiotic leads to emergence of drug resistant strains because antibiotics: A. Induce mutation in the bacteria B. Promote conjugation among bacteria C. Allow resistant strains to propagate preferentially D. All of the above
Last Answer : C. Allow resistant strains to propagate preferentially
Description : Which statement is correct for bacterial transduction? (a) Transfer of some genes from one bacteria to another bacteria through virus. (b) Transfer of genes from one bacteria to another bacteria ... its DNA directly from mother cell. (d) Bacteria obtained DNA from other external source.
Last Answer : (a) Transfer of some genes from one bacteria to another bacteria through virus.
Last Answer : (a) Transfer of some genes from one bacteria to another bacteria through virus
Description : The most important mechanism of bacterial resistance to an aminoglycoside antibiotic is: A. Plasmid mediated acquisition of aminoglycoside conjugating enzyme B. Mutational acquisition of aminoglycoside ... affinity of ribosomal protein for the antibiotic D. Mutational loss of porin channels
Last Answer : A. Plasmid mediated acquisition of aminoglycoside conjugating enzyme
Description : What is break point concentration of an antibiotic ? (a) Concentration at which the antibiotic lyses the bacteria (b) Concentration of the antibiotic which demarks between sensitive ... which overcomes bacterial resistance (d) Concentration at which a bacteriostatic antibiotic becomes bactericidal
Description : The mechanism of antibacterial action of tetracycline involves (a) Binding to a component of the 50S ribosomal subunit (b) Inhibition of translocase activity (c) Blockade of binding of ... (d) Selective inhibition of ribosomal peptidyl transferases (e) Inhibition of DNA-dependent RNA polymerase
Description : Which of the following transport bacterial DNA to other bacteria via bacteriophages? A- Conjugation B- Transduction C- Transformation D- Translation
Last Answer : Transduction
Description : What is the most important reason for restricted clinical use of chloramphenicol ? (a) Its narrow spectrum of activity (b) Emergence of chloramphenicol resistance (c) Its potential to cause bone marrow depression (d) Its potential to cause superinfections
Description : Important microbiological features of ciprofloxacin include the following except (a) Long postantibiotic effect (b) Marked suppression of intestinal anaerobes (c) MBC values close to MIC values (d) Slow development of resistance
Description : Cefotaxime has the following properties except (a) It is highly active against aerobic gram negative bacteria (b) It is the most active cephalosporin against Pseudomonas aeruginosa (c) It produces an active metabolite (d) It has achieved high cure rates in serious hospital acquired infections
Description : Clavulanic acid is combined with amoxicillin because (a) It kills bacteria that are not killed by-moxicillin (b) It reduces renal clearance of amoxicillin (c) It counteracts the adverse effects of amoxicillin (d) It inhibits beta lactamases that destroy amoxicillin
Description : Gram negative organisms are largely insensitive to benzyl penicillin because (a) They produce large quantities of penicillinase (b) They do not utilize D-alanine whose incorporation in the cell wall is ... lipoprotein-peptidoglycan multiplayer cell wall of gram-negative bacteria (d) Both (a) and (b)
Description : Which fluoroquinolone has markedly enhanced activity against gram positive bacteria and anaerobes ? (a) Pefloxacin (b) Ciprofloxacin (c) Sparfloxacin (d) Norfloxacin
Description : Superinfections are more common with (a) Use of narrow spectrum antibiotics (b) Short courses of antibiotics (c) Use of antibiotics that are completely absorbed from the small intestines (d) Use of antibiotic combinations covering both gram positive and gram negative bacteria
Description : Transfer of genetic information from one bacterium to another in the transduction process is through (a) bacteriophages released from the donor bacterial strain (b) another bacterium ... physical contact between donor and recipient strains (d) conjugation between opposite strain bacterium.
Last Answer : (a) bacteriophages released from the donor bacterial strain
Description : F factor plasmids play a major role in A.conjugation B.replication C.transduction D.trasnscription
Last Answer : A.conjugation
Last Answer : conjugation
Description : Select the fourth generation cephalosporin among the following (a) Cefpirome (b) Ceftizoxime (c) Ceftazidime (d) Cefuroxime
Description : The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is: A. Decreased permeability into the bacterial cell B. Acquisition of a plasmid encoded ... the bacterial ribosome for chloramphenicol D. Switching over from ribosomal to mitochondrial protein synthesi
Last Answer : B. Acquisition of a plasmid encoded for chloramphenicol acetyl transferas
Description : Can anyone help me understand antibiotic resistance?
Last Answer : Sorry there are a few grammar issues in the above but I can’t edit it anymore.
Description : Does misusing Polysporin create antibiotic resistance?
Last Answer : Define “misusing”.
Description : The aminoglycoside antibiotic which is distinguished by its resistance to bacterial aminoglycoside inactivating enzymes is (a) Kanamycin (b) Sisomicin (c) Amikacin (d) Tobramycin
Description : Which of the following organisms is notorious for developing antimicrobial resistance rapidly ? (a) Streptococcus pyogenes (b) Meningococcus (c) Treponema pallidum (d) Escherichia coli
Description : Beta - lactamase production by strains of Haemophilus influenzae, Moraxella catarrhalis, and Neissera gonorrhoeae confers resistance against penicillin G.which one of the following antibiotics is most likely to be ... ? (a) Ampicillin (b) Ceftriaxone (c) Clindamycin (d) Gentamicin (e) Piperacillin
Description : In a patient with culture-positive enterococcal endocarditis who has failed to respond to vancomycin because of resistance, the treatment most likely to be effective is (a) Clarithromycin (b) Erythromycin (c) Linezolid (d) Minocycline (e) Ticarcillin
Description : This drug has activity against many strains of Pseudomomas aeruginosa. However, when it is used alone, resistance has emerged during the course of treatment. The drug should not be used in ... with tazobactam (a) Amoxicillin (b) Aztreonam (c) Imipenem (d) Piperacillin (e) Vancomycin
Description : The most important reason for highly restricted use of penicillin G injections in present day therapeutics is its (a) Narrow spectrum of activity (b) Potential to cause hypersensitivity reaction (c) Short duration of action (d) Neurotoxicity
Description : Which one of the following statements about one daily dosing with aminoglycosides is false ? (a) It is convenient for outpatient therapy (b) Adjustment of dosage is less important in renal ... often less toxic than conventional (multiple)dosing regimens (e) Under-dosing is less of a problem
Description : What is transduction/transformation? -Biology
Last Answer : answer:
Description : Recombination of virus genomes occurs A- by transduction B- by transcription C- simultaneous infection of a host cell by two viruses with homologous chromosomes D- by transformation
Last Answer : simultaneous infection of a host cell by two viruses with homologous chromosomes