Description : if you suspect atrial flutter : Consider digoxin if not already in use because it frequently increases the conduction ratio and decreases the ventricular rate. , Avoid adrenergic and ... to the muscle decrease blood supply to the muscle the heart trying to beat fast ______________________________
Last Answer : decrease O2 supply to the muscle
Description : Smooth muscle relaxation is due to stimulation of which type of histamine receptors (a) H1 (b) H2 (c) H3 (d) All of the above
Last Answer : Ans: B
Description : The symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cell (e) Decreased prostaglandin production
Last Answer : Ans: A
Description : Select the correct statement about salmeterol. (a) It is a long acting selective ß2 agonist bronchodilator (b) It is a bronchodilator with anti-inflammatory property (c) It is a ß blocker that can be safely given to asthmatics (d) It is an antihistaminic with mast cells stabilizing property
Description : Which of the following is a prophylactic agent that appears to stabilize mast cells? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Description : The Symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cells (e) Decreased prostaglandin production
Description : The capacity of an antihistaminic to produce sedation depends on the following except (a) Relative affinity for central versus peripheral H1 receptors (b) Ability to penetrate blood-brain barrier (c) Individual susceptibility (d) Ratio of H1 : H2 blockade produced by the drug
Last Answer : Ans: D
Description : Which of the following drugs is neither bronchodilator nor anti-inflammatory, but has antihistaminic and mast cell stabilizing activity ? (a) Sodium cromoglycate (b) Ketotifen (c) Beclomethasone dipropionate (d) Mepyramine maleate
Description : Erythromycin should not be given to patient being treated with terfenadine because (a) Erythromycin induces the metabolism of terfenadine (b) Dangerous ventricular arrhythmias can occur ... inhibits metabolism of erythromycin (d) Terfenadine antagonizes the antimicrobal action of erythromycin
Description : The most important receptor involved in cytotoxic drug induced vomiting is (a) Histamine H1 receptor (b) Serotonin 5-HT3 receptor (c) Dopamine D2 receptor (d) Opioid µ receptor
Description : Tachyphylaxis to many actions on repeated injection is a feature of the following autocoid (a) Histamine (b) 5-Hydroxytryptamine (c) Bradykinin (d) Angiotensin
Description : Histamine is involved as a mediator in the following pathological conditon (a) Cocaine (b) Dibucaine (c) Lidocaine (d) Procaine
Description : Fall in blood pressure caused by larger doses of histamine is blocked by (a) H1 antihistaminics alone (b) H2 ANTAgonists alone (c) Combination of H1 and H2 antagonists (d) None of the above
Last Answer : Ans: C
Description : Which of the following is a selective H1 receptor agoinist ? (a) 4-methyl histamine (b) Impromidine (c) 2-Thiazolyl ethylamine (d) Mepyramine
Description : Answer: b, c, d Eosinophils constitute 1% to 3% of the leukocyte population of the bloodstream. They also reside in tissues and they exhibit phagocytic capabilities. They are less ... the cycle of events that result in recruitment and activation of inflammatory cells at sites of inflammation
Last Answer : Cellular injury from oxidants may be manifest by which of the following? a. Cell membrane lipid peroxidation b. DNA strand breaks c. Cytoskeletal disassembly d. ATP depletion
Description : Methylxanthine drugs such as aminophylline cause which one of the following? (a) Vasoconstriction in many vascular beds (b) Decrease in the amount of cAMP in mast cells (c) Bronchodilation (d) Activation of the enzyme phosphodiesterase (e) Sedation
Description : Which of the following agents and dosage regimens is the best choice of treatment for an asthma patient with rheumatoid arthritis who is considered sensitive to aspirin (experiences bronchospasm with use)? ... once a week (d) Azathioprine, 75 mg daily (e) Cyclophosphamide, 100 mg daily
Description : Which of the following body substances causes increased gastric secretion, dilation of capillaries, and constriction of the bronchial smooth muscle? a) Histamine When cells are damaged, ... Prostaglandin Prostaglandins are unsaturated fatty acids that have a wide assortment of biologic activity.
Last Answer : a) Histamine When cells are damaged, histamine is released.
Description : Caffeine is more powerful than theophylline in exerting the following action (a) Bronchodilatation (b) Cardiac stimulation (c) Diuresis (d) Augmentation of skeletal muscle contractility
Description : Bronchodilators are useful in cough (a) Only when cough is non-productive (b) Only when cough is associated with thick sticky secretions (c) Only when reflex bronchoconstriction is associated (d) ... Rise in blood pressure (b) Muscle tremor (c) Hyperglycaemia (d) Central nervous system stimulation
Description : The smooth muscle stimulating action of 5-HT is most marked in the (a) Bronchi (b) Intestines (c) Ureter (d) Billary tract
Description : Which of the following will result from blockade of H2 receptors? (a) Decreased camp in cardiac muscle (b) Increased camp in cardiac muscle (c) Decreased IP3 in gastric mucosa (d) Increased IP3 in gastric mucosa (e) Increased IP3 in smooth muscle
Description : Select the correct statement with respect to disorders of muscles in humans. (a) Failure of neuromuscular transmission in myasthenia gravis can prevent normal swallowing. (b) Accumulation of ... of vitamin D causes osteoporosis. (d) Rapid contractions of skeletal muscles cause muscle dystrophy
Last Answer : (a) Failure of neuromuscular transmission in myasthenia gravis can prevent normal swallowing.
Description : Chronic Bronchitis is characterized by I. the distruction of central and peripheral portions of the acinus II. an increased number of mucous glands and goblet cells III. edema and inflammation of the bronchioles (a) only ... II are correct (d) II and III are correct (e) I, II and III are correct
Description : n human adult females oxytocin (a) stimulates pituitary to secrete vasopressin (b) causes strong uterine contractions during parturition (c) is secreted by anterior pituitary (d) stimulates growth of mammary glands.
Last Answer : (b) causes strong uterine contractions during parturition
Description : Histamine is synthesised in (A) Brain (B) Mast cells (C) Basophils (D) All of these
Last Answer : Answer : D
Description : A mast cell (or mastocyte) is a resident cells of several types of tissues and contains many granules rich in_______. a) Acetylcholine b) Nicotine c) Epinephrine d) Histamine e) Histadine
Description : In mammals, histamine is secreted by (a) lymphocytes (b) mast cells (c) fibroblasts (d) histiocytes.
Last Answer : b) mast cells
Description : Mast cells of connective tissue contain (a) vasopressin and relaxin (b) heparin and histamine (c) heparin and calcitonin (d) serotonin and melanin.
Last Answer : (b) heparin and histamine
Description : Mast cells secrete (a) haemoglobin (b) hippurin (c) myoglobin (d) histamine
Last Answer : (d) histamine.
Description : ________ bind to_________ on microbial invaders. a. Toll-like receptors; PAM Ps b. Mast cells; histamine c. Toll-like receptors; complement d. Macrophages; defensins
Last Answer : a. Toll-like receptors; PAM Ps
Description : The drug that can directly release histamine from mast cells without involving antigen-antibody reaction is: A. Aspirin B. Procaine C. Morphine D. Sulfadiazine
Last Answer : C. Morphine
Description : In a patient of bronchial asthma, inhaled salbutamol produces the following effect(s). (a) Inhibits antigen-antibody reaction in the lungs (b) Causes bronchodilatation (c) Reduces bronchial hyperreactivity (d) Both (b) and (c)
Description : If therapy with multiple drugs causes induction of drug metabolism in your asthma patient, it will (a) Result in increased smooth endoplasmic reticulum (b) Result in increased rough endoplasmic reticulum ... soluble cytoplasmic fraction (d) Require 3-4 months to reach completion (e) Be irreversible
Description : Relative to fexofenadine, diphenhydramine is more likely to (a) Be used for treatment of asthma (b) Be used for treatment of gastroesophageal reflux disease (c) Cause cardiac arrhythmias in ... ) Have efficacy in the prevention of motion sickness (e) Increase the serum concentration of warfarin
Description : In an asthma patient treated with systemic corticosteroids, bronchodilator drugs (a) Are not needed (b) Are contraindicated (c) May be used on ‘as and when required’ basis (d) Are ineffective
Description : Which of the following may precipitate an asthma attack? (a) Respiratory acidosis (b) Viran and bacterial infections (c) Respiratory alkalosis (d) Cranberry jiuce (e) Chocolate or Coca Cola
Description : Which of the following are not determinants of a postoperative cardiac complication? A. Myocardial infarct 4 months previously. B. Clinical evidence of congestive heart failure in a patient with 8.5 gm ... on electrocardiogram. D. A harsh aortic systolic murmur. E. Age over 70 years.
Last Answer : Answer: B DISCUSSION: Clinical evidence of congestive heart failure in a patient with 8.5 gm. per dl. hemoglobin concentration is a misleading sign. Evidence of congestive ... or ventricular contractions on the electrocardiogram are less strong determinants of a postoperative cardiac complication
Description : Premature ventricular contractions are considered precursors of ventricular tachycardia when they a) occur at a rate of more than six per minute. When PVCs occur at a rate of more than six per minute they ... paired with a normal beat. A PVC that is paired with a normal beat is termed bigeminy.
Last Answer : a) occur at a rate of more than six per minute. When PVCs occur at a rate of more than six per minute they indicate increasing ventricular irritability and are considered forerunners of ventricular tachycardia (VT).
Description : During the course of a cellular hypersensitivity a. Antibodies react with antigens in tissues. b. Serotonin and histamine are released by cells. c. Immune complexes form on blood vessel surfaces. d. A skin thickening called an induration may form.
Last Answer : b. Serotonin and histamine are released by cells.
Description : When the nurse observes an ECG tracing on a cardiac monitor with a pattern in lead II and observes a bizarre, abnormal shape to the QRS complex, the nurse has likely ... Ventricular fibrillation is a rapid but disorganized ventricular rhythm that causes ineffective quivering of the ventricles.
Last Answer : a) Ventricular bigeminy Ventricular bigeminy is a rhythm in which every other complex is a PVC.
Description : Following is an example of preformed and not lipid derived mast cell mediator of inflammatory process (a) LTC4 (b) PGD2 (c) PAF (d) Histamine
Description : Acute exacerbations of asthma can be triggered by all of the following except (a) Bacterial or viral pneumonia (b) Hypersensitivity reaction to penicillin (c) Discontinuation of asthma medication (d) Hot, dry weather (e) Stressful emotional events
Description : Bacteria that make either a fementative or respiratory set of enzymes are known as (a) Obligate anacerobes (b) Obligate aerobes (c) Microacerophiles (d) Facultative organisms
Description : A drug useful in the treatment of asthma but lacking bronchodilator action, is (a) Cromolyn (b) Ephedrine (c) Isoproterenol (d) Metaproterenol (e) Metoprolol
Description : Which one of the following drugs is most suitable for management of essential tremor in a patient who has pulmonary disease? (a) Diazepam (b) Levodopa (c) Metoprolol (d) Propranolol (e) Terbutaline
Description : Which of the following is a very longacting ß2 – selective agonist that is used for asthma prophylaxis? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Salmeterol
Last Answer : Ans: E
Description : Which of the following has overdose toxicity that includes insomnia, arrhythmias, and convulsions? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Description : Acute exacerbations of asthma can be triggered by all of the following except (a) Bacterial of viral pneumonia (b) Hypertsensitivity reaction to penicillin (c) Discontinuation of asthma medication (d) Hot, dry weather (e) Stressful emotional events