Description : A drug administered by inhalation of powder as a prophylactic for asthma is (a) Ephedrine (b) Disodium cromolyn (c) Isoproterenol (d) Ocytriphylline (e) Epinephrine
Last Answer : Ans: B
Description : Which of the following is a direct bronchodilator that is most often used in asthma by the oral route? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Last Answer : Ans: A
Description : Which of the following is a nonselective but very potent and efficacious bonchodilator that is not active by the oral route? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Last Answer : Ans: C
Description : Which of the following has overdose toxicity that includes insomnia, arrhythmias, and convulsions? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Description : Which of the following is a prophylactic agent that appears to stabilize mast cells? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Description : To be a useful inhaled glucocorticoid the drug should have (a) High oral bioavailability (b) Low oral bioavailability (c) Additional bronchodilator activity (d) Prodrug character
Description : Which of the following is a very longacting ß2 – selective agonist that is used for asthma prophylaxis? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Salmeterol
Last Answer : Ans: E
Description : In the emergency department, the preferred first-line therapy for asthma exacerbation is (a) Theophylline (b) A ß-agonist (c) A corticosteroid (d) Cromolyn sodium (e) An antihistamine
Description : In the emergency department, the preferred first-line therapy for asthma exacerbation is (a) Theophyline (b) A ß-agonist (c) A corticosteroid (d) Cromolyn sodium (e) An antihistamine
Description : In an asthma patient treated with systemic corticosteroids, bronchodilator drugs (a) Are not needed (b) Are contraindicated (c) May be used on ‘as and when required’ basis (d) Are ineffective
Description : In patients of bronchial asthma inhaled corticosteroids achieve the following except (a) Reduce the need for bronchodilator medication (b) Control an attack of refractory asthma (c) Reduce bronchial hyperreactivity (d) Reverse diminished responsiveness to sympathomimetic bronchodilators
Description : Drugs used in asthma that often cause tachycardia and tremor include (a) Beclomethasone (b) Cromolyn sodium (c) Ipratropium (d) Metaproterenol (e) All of the above
Last Answer : Ans: D
Description : A drug lacking vasodilator properties that is useful in angina is (a) Isosorbide dinitrate (b) Metoprolol (c) NIfedipine (d) Nitroglycerin (e) Verapamil
Description : Which of the following drugs is neither bronchodilator nor anti-inflammatory, but has antihistaminic and mast cell stabilizing activity ? (a) Sodium cromoglycate (b) Ketotifen (c) Beclomethasone dipropionate (d) Mepyramine maleate
Description : Which one of the following drugs is most suitable for management of essential tremor in a patient who has pulmonary disease? (a) Diazepam (b) Levodopa (c) Metoprolol (d) Propranolol (e) Terbutaline
Description : If therapy with multiple drugs causes induction of drug metabolism in your asthma patient, it will (a) Result in increased smooth endoplasmic reticulum (b) Result in increased rough endoplasmic reticulum ... soluble cytoplasmic fraction (d) Require 3-4 months to reach completion (e) Be irreversible
Description : Select the correct statement about salmeterol. (a) It is a long acting selective ß2 agonist bronchodilator (b) It is a bronchodilator with anti-inflammatory property (c) It is a ß blocker that can be safely given to asthmatics (d) It is an antihistaminic with mast cells stabilizing property
Description : Relative to fexofenadine, diphenhydramine is more likely to (a) Be used for treatment of asthma (b) Be used for treatment of gastroesophageal reflux disease (c) Cause cardiac arrhythmias in ... ) Have efficacy in the prevention of motion sickness (e) Increase the serum concentration of warfarin
Description : Which of the following agents and dosage regimens is the best choice of treatment for an asthma patient with rheumatoid arthritis who is considered sensitive to aspirin (experiences bronchospasm with use)? ... once a week (d) Azathioprine, 75 mg daily (e) Cyclophosphamide, 100 mg daily
Description : Budesonide is a (a) Nonsteroidal anti-inflammatory drug (b) High ceiling diuretic (c) Inhaled corticosteroid for asthma (d) Contraceptive
Description : A 10 year old child suffers from exercise induced asthma: Which is the most suitable first line drug for regular prophylactic therapy ? (a) Oral salbutamol (b) Oral theophylline (c) Inhaled sodium cromoglycate (d) Inhaled beclomethasone dipropionate
Description : The National Institutes of Health (NIH) guidelines for the treatment of asthma recommended institution of routine inhaled corticosteroids when patients are classified as having greater than or equal to which ... (a) Mild intermittent (b) Mild persistent (c) Moderate persistent (d) Severe persistent
Description : Delicious chilgoza seeds, commercially important products such as turpentine and resin and the drug ephedrine, useful in asthma and other respiratory ailments, are all obtained from plants that are (a) Ferns (b) Algae (c) Monocotyledons and dicotyledons (d) Gymnosperms
Last Answer : Ans:(d)
Description : Which of the following is most useful in the treatment of hyperprolactinemia ? (a) Bromocriptine (b) Cimetidine (c) Ergotamine (d) Ketanserin (e) LSD
Description : Acute exacerbations of asthma can be triggered by all of the following except (a) Bacterial or viral pneumonia (b) Hypersensitivity reaction to penicillin (c) Discontinuation of asthma medication (d) Hot, dry weather (e) Stressful emotional events
Description : The symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cell (e) Decreased prostaglandin production
Description : Acute exacerbations of asthma can be triggered by all of the following except (a) Bacterial of viral pneumonia (b) Hypertsensitivity reaction to penicillin (c) Discontinuation of asthma medication (d) Hot, dry weather (e) Stressful emotional events
Description : Which of the following tests is used at home to assess therapy and determine if a patient with asthma should seek emergency care? (a) Forced expiratory volume in one second (FEV1) (b) Forced vital capacity ... ) Total lung capacity (TLC) (d) Peak expiratory flow rate (PEFR) (e) Residual volume (RV)
Description : The primary goals of asthma therapy include all of the following except (a) maintain normal activity levels (b) maintain control of symptoms (c) avoid adverse effects of asthma medications (d) prevent acute exacerbations and chronic symptoms (e) prevent destruction of lung tissue
Description : Isoxuprine is used to treat (a) Asthma (b) Severe hypotension (c) Nasal congestion (d) Premature labor (e) Hypertension
Description : Which of the following may precipitate an asthma attack? (a) Respiratory acidosis (b) Viran and bacterial infections (c) Respiratory alkalosis (d) Cranberry jiuce (e) Chocolate or Coca Cola
Description : The Symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cells (e) Decreased prostaglandin production
Description : Which of the following terms best describes the antagonism of leukotriene's bronchoconstrictor effect (mediated at leukotriene receptors) by terbutaline (acting a adrenoceptors) in a patient with ... ) Partial agonist (c) Physiologic antagonist (d) Chemical antagonist (e) Noncompetitive antagonist
Description : Which xanthine derivative has no function in asthma ? (a) Theophylline (b) Pentoxyphyllin (c) Enprofylin (d) None of the above
Description : All the following are employed in inhalation therapy of asthma except (a) Beclomethasone (b) Budesonide (c) Dexamethasone (d) Triamcinolone
Description : The most consistent, pronounced and sustained relief of symptoms in chronic bronchial asthma is afforded by (a) ß2 sympathomimetics (b) Anticholinergics (c) Sodium cromoglycate (d) Corticosteroids
Description : In a patient of bronchial asthma, inhaled salbutamol produces the following effect(s). (a) Inhibits antigen-antibody reaction in the lungs (b) Causes bronchodilatation (c) Reduces bronchial hyperreactivity (d) Both (b) and (c)
Description : H1 antihistaminics are beneficial in (a) All types of allergic disorders (b) Certain type I allergic reactions only (c) Anaphylactic shock(d) Bronchial asthma
Description : A 7-years-old boy has a significant bedwetting problem. A long-acting indirect sympathomimetic agent sometimes used by the oral route for this and other indications is (a) Dobutamine (b) Ephedrine (c) Epinephrine (d) Isoproterenol (e) Phenylephrine
Description : Bronchodilators are useful in cough (a) Only when cough is non-productive (b) Only when cough is associated with thick sticky secretions (c) Only when reflex bronchoconstriction is associated (d) ... Rise in blood pressure (b) Muscle tremor (c) Hyperglycaemia (d) Central nervous system stimulation
Description : A patient undergoing cancer chemotherapy is vomiting frequently. A drug that might help in this situation is (a) Bromocriptine (b) Cimetidine (c) Ketanserin (d) Loratadine (e) Ondansetron
Description : What is symport ? (a) Counter transport (b) Contransport (c) Carrier mediated diffusion (d) Solvent drug
Description : The antiasthma drug which cannot be administered by inhalation is (a) Theophylline (b) Ipratropium bromide (c) Budesonide (d) Terbutaline
Description : The most important receptor involved in cytotoxic drug induced vomiting is (a) Histamine H1 receptor (b) Serotonin 5-HT3 receptor (c) Dopamine D2 receptor (d) Opioid µ receptor
Description : The capacity of an antihistaminic to produce sedation depends on the following except (a) Relative affinity for central versus peripheral H1 receptors (b) Ability to penetrate blood-brain barrier (c) Individual susceptibility (d) Ratio of H1 : H2 blockade produced by the drug
Description : Methylxanthines exert the following action (s) at cellular/molecular level (a) Intracellular release of Ca2+ (b) Antagonism of adenosine (c) Inhibition of phosphodiesterase (d) All of the above
Description : Caffeine is more powerful than theophylline in exerting the following action (a) Bronchodilatation (b) Cardiac stimulation (c) Diuresis (d) Augmentation of skeletal muscle contractility
Description : The smooth muscle stimulating action of 5-HT is most marked in the (a) Bronchi (b) Intestines (c) Ureter (d) Billary tract
Description : The action of 5-Hydroxy tryptamine mediated by the 5-HT3 receptor is (a) Vasoconstriction (b) Bradycardia (c) EDRF release (d) Platelet aggregation