Bronchodilators are useful in cough (a) Only when cough is non-productive (b) Only when cough is associated with thick sticky secretions (c) Only when reflex bronchoconstriction is associated (d) Irrespective of nature of cough or associated features Ans: C 51 The common and dose related side effect of salbutamol is (a) Rise in blood pressure (b) Muscle tremor (c) Hyperglycaemia (d) Central nervous system stimulation

Bronchodilators are useful in cough (a) Only when cough is non-productive (b) Only when cough is associated with thick sticky secretions (c) Only when reflex bronchoconstriction is associated (d) Irrespective of nature of cough or associated features Ans: C  51 The common and dose related side effect of salbutamol is (a) Rise in blood pressure (b) Muscle tremor (c) Hyperglycaemia (d) Central nervous system stimulation
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Bronchodilators are useful in cough: A. Only when cough is nonproductive B. Only when cough is associated with thick sticky secretions C. Only when reflex bronchoconstriction is associated D. Irrespective of nature of cough or associated features

Description : Bronchodilators are useful in cough: A. Only when cough is nonproductive B. Only when cough is associated with thick sticky secretions C. Only when reflex bronchoconstriction is associated D. Irrespective of nature of cough or associated features

Last Answer : C. Only when reflex bronchoconstriction is associated

The most prominent and dose related side effect of salbutamol is: A. Rise in blood pressure B. Muscle tremor C. Hyperglycaemia D. Central nervous system stimulation

Description : The most prominent and dose related side effect of salbutamol is: A. Rise in blood pressure B. Muscle tremor C. Hyperglycaemia D. Central nervous system stimulation

Last Answer : B. Muscle tremor

__________ is the common and dose related side effect of salbutamol. a) Decrease in blood pressure b) Muscle tremor c) Central nervous system stimulation d) Hyperglycaemia

Description : __________ is the common and dose related side effect of salbutamol. a) Decrease in blood pressure b) Muscle tremor c) Central nervous system stimulation d) Hyperglycaemia

Last Answer : c) Central nervous system stimulation 

Antitussives act by (a) Liquifying bronchial secretions (b) Raising the threshold of cough centre (c) Reducing cough inducing impulses from the lungs (d) Both (b) and (c)

Description : Antitussives act by (a) Liquifying bronchial secretions (b) Raising the threshold of cough centre (c) Reducing cough inducing impulses from the lungs (d) Both (b) and (c)

Last Answer : Ans: D

In a patient of bronchial asthma, inhaled salbutamol produces the following effect(s). (a) Inhibits antigen-antibody reaction in the lungs (b) Causes bronchodilatation (c) Reduces bronchial hyperreactivity (d) Both (b) and (c)

Description : In a patient of bronchial asthma, inhaled salbutamol produces the following effect(s). (a) Inhibits antigen-antibody reaction in the lungs (b) Causes bronchodilatation (c) Reduces bronchial hyperreactivity (d) Both (b) and (c)

Last Answer : Ans: B

In patients of bronchial asthma inhaled corticosteroids achieve the following except (a) Reduce the need for bronchodilator medication (b) Control an attack of refractory asthma (c) Reduce bronchial hyperreactivity (d) Reverse diminished responsiveness to sympathomimetic bronchodilators

Description : In patients of bronchial asthma inhaled corticosteroids achieve the following except (a) Reduce the need for bronchodilator medication (b) Control an attack of refractory asthma (c) Reduce bronchial hyperreactivity (d) Reverse diminished responsiveness to sympathomimetic bronchodilators

Last Answer : Ans: B

Smooth muscle relaxation is due to stimulation of which type of histamine receptors (a) H1 (b) H2 (c) H3 (d) All of the above

Description : Smooth muscle relaxation is due to stimulation of which type of histamine receptors (a) H1 (b) H2 (c) H3 (d) All of the above

Last Answer : Ans: B

Caffeine is more powerful than theophylline in exerting the following action (a) Bronchodilatation (b) Cardiac stimulation (c) Diuresis (d) Augmentation of skeletal muscle contractility

Description : Caffeine is more powerful than theophylline in exerting the following action (a) Bronchodilatation (b) Cardiac stimulation (c) Diuresis (d) Augmentation of skeletal muscle contractility

Last Answer : Ans: D

A 10 year old child suffers from exercise induced asthma: Which is the most suitable first line drug for regular prophylactic therapy ? (a) Oral salbutamol (b) Oral theophylline (c) Inhaled sodium cromoglycate (d) Inhaled beclomethasone dipropionate

Description : A 10 year old child suffers from exercise induced asthma: Which is the most suitable first line drug for regular prophylactic therapy ? (a) Oral salbutamol (b) Oral theophylline (c) Inhaled sodium cromoglycate (d) Inhaled beclomethasone dipropionate

Last Answer : Ans: C

Which one of the following drugs is most suitable for management of essential tremor in a patient who has pulmonary disease? (a) Diazepam (b) Levodopa (c) Metoprolol (d) Propranolol (e) Terbutaline

Description : Which one of the following drugs is most suitable for management of essential tremor in a patient who has pulmonary disease? (a) Diazepam (b) Levodopa (c) Metoprolol (d) Propranolol (e) Terbutaline

Last Answer : Ans: C

Terbutaline has a preference for stimulation of which of the following receptors? (a) Alpha (b) Gamma (c) Beta 1 (d) Beta 2 (e) Dopaminergic

Description : Terbutaline has a preference for stimulation of which of the following receptors? (a) Alpha (b) Gamma (c) Beta 1 (d) Beta 2 (e) Dopaminergic

Last Answer : Ans: D

Reflex bronchoconstriction is most likely to occur with the following form of inhaled antiasthma medication: A. Metered dose spray of drug in solution B. Dry powder rotacap C. Nebuliser D. Nebuliser with spacer

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Last Answer : B. Dry powder rotacap

Bromhexine acts by (a) Inhibiting cough center (b) Irritating gastric mucosa and reflexly increasing bronchial secretion (c) Depolymerizing mucopolysaccharides present (d) Desensitizing stretch receptors in the lungs

Description : Bromhexine acts by (a) Inhibiting cough center (b) Irritating gastric mucosa and reflexly increasing bronchial secretion (c) Depolymerizing mucopolysaccharides present (d) Desensitizing stretch receptors in the lungs

Last Answer : Ans: C

Inhaled ipratropium bromide has the following advantages except: A. It does not alter respiratory secretions B. It does not depress airway mucociliary clearance C. It has faster onset of bronchodilator action than inhaled salbutamol D. It only rarely produces systemic side effects

Description : Inhaled ipratropium bromide has the following advantages except: A. It does not alter respiratory secretions B. It does not depress airway mucociliary clearance C. It has faster onset of bronchodilator action than inhaled salbutamol D. It only rarely produces systemic side effects

Last Answer : C. It has faster onset of bronchodilator action than inhaled salbutamol

Inhaled ipratropium bromide has the following advantages except: A. It does not alter respiratory secretions B. It does not depress airway mucociliary clearance C. It has faster onset of bronchodilator action than inhaled salbutamol D. It only rarely produces systemic side effects

Description : Inhaled ipratropium bromide has the following advantages except: A. It does not alter respiratory secretions B. It does not depress airway mucociliary clearance C. It has faster onset of bronchodilator action than inhaled salbutamol D. It only rarely produces systemic side effects

Last Answer : C. It has faster onset of bronchodilator action than inhaled salbutamol

Relatively higher dose of theophylline is required to attain therapeutics plasma concentration in (a) Smokers (b) Congestive heart failure patients (c) Those receiving erythromycin (d) Those receiving cimetidine

Description : Relatively higher dose of theophylline is required to attain therapeutics plasma concentration in (a) Smokers (b) Congestive heart failure patients (c) Those receiving erythromycin (d) Those receiving cimetidine

Last Answer : Ans: A

The capacity of an antihistaminic to produce sedation depends on the following except (a) Relative affinity for central versus peripheral H1 receptors (b) Ability to penetrate blood-brain barrier (c) Individual susceptibility (d) Ratio of H1 : H2 blockade produced by the drug

Description : The capacity of an antihistaminic to produce sedation depends on the following except (a) Relative affinity for central versus peripheral H1 receptors (b) Ability to penetrate blood-brain barrier (c) Individual susceptibility (d) Ratio of H1 : H2 blockade produced by the drug

Last Answer : Ans: D

Chronic Bronchitis is characterized by I. the distruction of central and peripheral portions of the acinus II. an increased number of mucous glands and goblet cells III. edema and inflammation of the bronchioles (a) only I is correct (b) only III is correct (c) I and II are correct (d) II and III are correct (e) I, II and III are correct

Description : Chronic Bronchitis is characterized by I. the distruction of central and peripheral portions of the acinus II. an increased number of mucous glands and goblet cells III. edema and inflammation of the bronchioles (a) only ... II are correct (d) II and III are correct (e) I, II and III are correct

Last Answer : Ans: C

Histamine (a) May be released from mast cells by a number of therapeutic agents (b) Causes sedation (c) Decreases the force of contraction of ventricular muscle (d) Can cause strong contractions of the gravid human uterus

Description : Histamine (a) May be released from mast cells by a number of therapeutic agents (b) Causes sedation (c) Decreases the force of contraction of ventricular muscle (d) Can cause strong contractions of the gravid human uterus

Last Answer : Ans: D

The smooth muscle stimulating action of 5-HT is most marked in the (a) Bronchi (b) Intestines (c) Ureter (d) Billary tract

Description : The smooth muscle stimulating action of 5-HT is most marked in the (a) Bronchi (b) Intestines (c) Ureter (d) Billary tract

Last Answer : Ans: B

Which of the following will result from blockade of H2 receptors? (a) Decreased camp in cardiac muscle (b) Increased camp in cardiac muscle (c) Decreased IP3 in gastric mucosa (d) Increased IP3 in gastric mucosa (e) Increased IP3 in smooth muscle

Description : Which of the following will result from blockade of H2 receptors? (a) Decreased camp in cardiac muscle (b) Increased camp in cardiac muscle (c) Decreased IP3 in gastric mucosa (d) Increased IP3 in gastric mucosa (e) Increased IP3 in smooth muscle

Last Answer : Ans: A

A drug useful in the treatment of asthma but lacking bronchodilator action, is (a) Cromolyn (b) Ephedrine (c) Isoproterenol (d) Metaproterenol (e) Metoprolol

Description : A drug useful in the treatment of asthma but lacking bronchodilator action, is (a) Cromolyn (b) Ephedrine (c) Isoproterenol (d) Metaproterenol (e) Metoprolol

Last Answer : Ans: A

To be a useful inhaled glucocorticoid the drug should have (a) High oral bioavailability (b) Low oral bioavailability (c) Additional bronchodilator activity (d) Prodrug character

Description : To be a useful inhaled glucocorticoid the drug should have (a) High oral bioavailability (b) Low oral bioavailability (c) Additional bronchodilator activity (d) Prodrug character

Last Answer : Ans: B

Which of the following is most useful in the treatment of hyperprolactinemia ? (a) Bromocriptine (b) Cimetidine (c) Ergotamine (d) Ketanserin (e) LSD

Description : Which of the following is most useful in the treatment of hyperprolactinemia ? (a) Bromocriptine (b) Cimetidine (c) Ergotamine (d) Ketanserin (e) LSD

Last Answer : Ans: A

Which of the following is seen at low (analgesic) doses of aspirin: A. Respiratory stimulation B. Increased occult blood loss in stools C. Increased cardiac output D. Hyperglycaemia

Description :  Which of the following is seen at low (analgesic) doses of aspirin: A. Respiratory stimulation B. Increased occult blood loss in stools C. Increased cardiac output D. Hyperglycaemia

Last Answer : B. Increased occult blood loss in stools

The side effect of a drug which has been used as a therapeutic effect in another condition is: A. Constipation caused by codeine B. Cough caused by captopril C. Uterine stimulation caused by quinine D. Diarrhoea caused by ampicillin

Description : The side effect of a drug which has been used as a therapeutic effect in another condition is: A. Constipation caused by codeine B. Cough caused by captopril C. Uterine stimulation caused by quinine D. Diarrhoea caused by ampicillin

Last Answer : A. Constipation caused by codeine

The side effect of a drug which has been used as a therapeutic effect in another condition is: A. Constipation caused by codeine B. Cough caused by captopril C. Uterine stimulation caused by quinine D. Diarrhoea caused by ampicillin

Description : The side effect of a drug which has been used as a therapeutic effect in another condition is: A. Constipation caused by codeine B. Cough caused by captopril C. Uterine stimulation caused by quinine D. Diarrhoea caused by ampicillin

Last Answer : A. Constipation caused by codeine

The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case

Description : The antiparkinsonian action of central anticholinergics has the following features except: A. They control tremor more than rigidity B. They produce a low ceiling therapeutic effect C. They are effective in neuroleptic drug induced parkinsonism D. They are the preferred drugs in advanced case

Last Answer : D. They are the preferred drugs in advanced cases

Fall in blood pressure caused by larger doses of histamine is blocked by (a) H1 antihistaminics alone (b) H2 ANTAgonists alone (c) Combination of H1 and H2 antagonists (d) None of the above

Description : Fall in blood pressure caused by larger doses of histamine is blocked by (a) H1 antihistaminics alone (b) H2 ANTAgonists alone (c) Combination of H1 and H2 antagonists (d) None of the above

Last Answer : Ans: C

Pyridostigmine differs from neostigmine in that (a) More potent orally (b) Longer acting (c) Less muscarinic side effects (d) All of the above

Description : Pyridostigmine differs from neostigmine in that (a) More potent orally (b) Longer acting (c) Less muscarinic side effects (d) All of the above

Last Answer : Ans: B

Intravenous injection of quinine produces: A. Rise in blood pressure B. Neuromuscular block C. Hyperglycaemia D. Hypoglycaemia

Description : Intravenous injection of quinine produces: A. Rise in blood pressure B. Neuromuscular block C. Hyperglycaemia D. Hypoglycaemia

Last Answer : D. Hypoglycaemia

Which of the following terms best describes the antagonism of leukotriene’s bronchoconstrictor effect (mediated at leukotriene receptors) by terbutaline (acting a adrenoceptors) in a patient with asthma? (a) Pharmacologic antagonist (b) Partial agonist (c) Physiologic antagonist (d) Chemical antagonist (e) Noncompetitive antagonist

Description : Which of the following terms best describes the antagonism of leukotriene's bronchoconstrictor effect (mediated at leukotriene receptors) by terbutaline (acting a adrenoceptors) in a patient with ... ) Partial agonist (c) Physiologic antagonist (d) Chemical antagonist (e) Noncompetitive antagonist

Last Answer : Ans: C

Choose the correct statement about cysteinyl leukotrienes (LT-C4/D4): A. They produce long lasting bronchoconstriction B. They produce sustained rise in blood pressure C. They are responsible for attracting and sequestrating neutrophils at the site of inflammation D. Their production is inhibited by rofecoxib

Description : Choose the correct statement about cysteinyl leukotrienes (LT-C4/D4): A. They produce long lasting bronchoconstriction B. They produce sustained rise in blood pressure C. They are responsible ... and sequestrating neutrophils at the site of inflammation D. Their production is inhibited by rofecoxib

Last Answer : A. They produce long lasting bronchoconstriction

Intransasal spray of budesonide is indicated in (a) Common cold (b) Acute vasomotor rhinitis (c) Perennial vasomotor rhinitis (d) Epistaxis

Description : Intransasal spray of budesonide is indicated in (a) Common cold (b) Acute vasomotor rhinitis (c) Perennial vasomotor rhinitis (d) Epistaxis

Last Answer : Ans: C

Atropine does not antagonise the following feature of anticholinesterase poisoning: A. Hypotension B. Central excitation C. Muscle paralysis D. Bronchoconstriction

Description : Atropine does not antagonise the following feature of anticholinesterase poisoning: A. Hypotension B. Central excitation C. Muscle paralysis D. Bronchoconstriction

Last Answer : C. Muscle paralysis

Atropine does not antagonise the following feature of anticholinesterase poisoning: A. Hypotension B. Central excitation C. Muscle paralysis D. Bronchoconstriction

Description : Atropine does not antagonise the following feature of anticholinesterase poisoning: A. Hypotension B. Central excitation C. Muscle paralysis D. Bronchoconstriction

Last Answer : C. Muscle paralysis

The pain sensation a. arises from stimulation of free nerve endings b. is transmitted to the central nervous system by unmyelinated C fibres c. is transmitted to the brain via the spinothalamic tracts d. all above

Description : The pain sensation a. arises from stimulation of free nerve endings b. is transmitted to the central nervous system by unmyelinated C fibres c. is transmitted to the brain via the spinothalamic tracts d. all above

Last Answer : all above

The pain sensation a. arises from stimulation of free nerve endings b. is transmitted to the central nervous system by unmyelinated C fibres c. is transmitted to the brain via the spinothalamic tracts d. is reduced by local anaesthetics through reduction of the potassium influx into the nerve fibres

Description : The pain sensation a. arises from stimulation of free nerve endings b. is transmitted to the central nervous system by unmyelinated C fibres c. is transmitted to the brain via the ... d. is reduced by local anaesthetics through reduction of the potassium influx into the nerve fibres

Last Answer : is transmitted to the brain via the spinothalamic tracts

Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Description : Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Last Answer : C. It is less liable to cause abrupt first dose hypotension

H1 antihistaminics are beneficial in (a) All types of allergic disorders (b) Certain type I allergic reactions only (c) Anaphylactic shock(d) Bronchial asthma

Description : H1 antihistaminics are beneficial in (a) All types of allergic disorders (b) Certain type I allergic reactions only (c) Anaphylactic shock(d) Bronchial asthma

Last Answer : Ans: B

Which controls reflex action? Options: A) Sympathetic nervous system B) Central nervous system C) Parasympathetic nervous system D) Sensory nerves

Description : Which controls reflex action? Options: A) Sympathetic nervous system B) Central nervous system C) Parasympathetic nervous system D) Sensory nerves

Last Answer : C) Parasympathetic nervous system

The following statements are true of oral anticoagulants except: A. They interfere with an early step in the synthesis of clotting factors B. Irrespective of the dose administered, their anticoagulant effect has a latency of onset of 1-3 days C. Their dose is adjusted by repeated measurement of prothrombin time D. They are contraindicated during pregnancy

Description : The following statements are true of oral anticoagulants except: A. They interfere with an early step in the synthesis of clotting factors B. Irrespective of the dose administered, their ... dose is adjusted by repeated measurement of prothrombin time D. They are contraindicated during pregnancy

Last Answer : A. They interfere with an early step in the synthesis of clotting factors

The tubular and dorsal nervous system of chordates is related to the cephalization in these animals and to bilateral symmetry. The presence of neural integrating centers with concentration of neurons in the brains and the spinal cord (central nervous system, CNS) allowed the increase of the interaction complexity between these animals and the environment. Receptor (afferent conduction) and efferent (motor, regulatory and behavioral reactions) functions come out more sophisticated in chordates due to the presence of more well-developed neural networks. These features have been preserved by evolution as they provide adaptive advantage to their owners.

Description : The tubular and dorsal nervous system of chordates is related to the cephalization in these animals and to bilateral symmetry. The presence of neural integrating centers with concentration of ... These features have been preserved by evolution as they provide adaptive advantage to their owners.

Last Answer : How can the tubular-dorsal nervous system in chordates be compared to the nervous pattern present in invertebrates?

A 17-year-old patient involved in an automobile accident is paralyzed with multiple peripheral extremity injuries. Nutritional support is instituted with a transnasal feeding catheter. Which of the following statement(s) is/are true concerning the patient’s management? a. Feeding into the stomach results in stimulation of the biliary/pancreatic axis which is probably trophic for small bowel b. Gastric secretions will dilute the feedings increasing the risk of diarrhea c. The major risk in this patient is tracheobronchial aspiration d. Placement of the feeding catheter through the pylorus into the first portion of the duodenum reduces the risk of regurgitation and aspiration

Description : A 17-year-old patient involved in an automobile accident is paralyzed with multiple peripheral extremity injuries. Nutritional support is instituted with a transnasal feeding catheter. Which of the ... pylorus into the first portion of the duodenum reduces the risk of regurgitation and aspiration

Last Answer : Answer: a, c, d The use of transnasal feeding catheters for intragastric feeding or for duodenal intubation are popular adjuncts for providing nutritional support by the enteral route. The ... the fourth portion of the duodenum reduces the risk of regurgitation and aspiration of feeding formulas

An Afro-Carribean male aged 48 years presents with gradual onset of exertional dyspnoea, non productive cough, malaise, weight loss and polyarthralgia. Schirmers test indicates a dry eye. X-ray of the hand shows punched out osteopenic lesions. Which of the following investigation is unlikely to be helpful in establishing the diagnosis of this condition: 1) Serum calcium 2) Serum phosphorus 3) Urea and electrolytes 4) Thallium Scan 5) Quantitative Immunoglobulins.

Description : An Afro-Carribean male aged 48 years presents with gradual onset of exertional dyspnoea, non productive cough, malaise, weight loss and polyarthralgia. Schirmers test indicates a dry eye. X-ray ... 2) Serum phosphorus 3) Urea and electrolytes 4) Thallium Scan 5) Quantitative Immunoglobulins.

Last Answer : Answers-4 This condition is sarcoidosis. Serum calcium, Serum phosphorus, Chem7 and Chem 20 and Quantitative Immunoglobulins are all used in establishing the diagnosis. Gallium scan is helpful in ... areas of poor perfusion. It is particularly used in cardiology to detect areas of ischaemia.

Antiinflammatory dose of aspirin given to diabetics is prone to cause: A. Hyperglycaemia B. Hypoglycaemia C. Ketoacidosis D. Alkalosis

Description :  Antiinflammatory dose of aspirin given to diabetics is prone to cause: A. Hyperglycaemia B. Hypoglycaemia C. Ketoacidosis D. Alkalosis

Last Answer : B. Hypoglycaemia

Acute exacerbations of asthma can be triggered by all of the following except (a) Bacterial or viral pneumonia (b) Hypersensitivity reaction to penicillin (c) Discontinuation of asthma medication (d) Hot, dry weather (e) Stressful emotional events

Description : Acute exacerbations of asthma can be triggered by all of the following except (a) Bacterial or viral pneumonia (b) Hypersensitivity reaction to penicillin (c) Discontinuation of asthma medication (d) Hot, dry weather (e) Stressful emotional events

Last Answer : Ans: D

The symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) Inceased vascular permeability of bronchial tissue (d) Decreased calcium influx into the mast cell (e) Decreased prostaglandin production

Description : The symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cell (e) Decreased prostaglandin production

Last Answer : Ans: A

Bacteria that make either a fementative or respiratory set of enzymes are known as (a) Obligate anacerobes (b) Obligate aerobes (c) Microacerophiles (d) Facultative organisms

Description : Bacteria that make either a fementative or respiratory set of enzymes are known as (a) Obligate anacerobes (b) Obligate aerobes (c) Microacerophiles (d) Facultative organisms

Last Answer : Ans: D

Relative to fexofenadine, diphenhydramine is more likely to (a) Be used for treatment of asthma (b) Be used for treatment of gastroesophageal reflux disease (c) Cause cardiac arrhythmias in overdose (d) Have efficacy in the prevention of motion sickness (e) Increase the serum concentration of warfarin

Description : Relative to fexofenadine, diphenhydramine is more likely to (a) Be used for treatment of asthma (b) Be used for treatment of gastroesophageal reflux disease (c) Cause cardiac arrhythmias in ... ) Have efficacy in the prevention of motion sickness (e) Increase the serum concentration of warfarin

Last Answer : Ans: D