Description : H1 antihistaminics are beneficial in: A. All types of allergic disorders B. Certain type I allergic reactions only C. Certain type IV allergic reactions only D. Bronchial asthma
Last Answer : B. Certain type I allergic reactions only
Description : While prescribing the conventional H1 antihistaminics the patient should be advised to avoid (a) Driving motor vehicles (b) Consuming processed cheese (c) Strenuous physical exertion (d) All of the above
Last Answer : Ans: A
Description : Fall in blood pressure caused by larger doses of histamine is blocked by (a) H1 antihistaminics alone (b) H2 ANTAgonists alone (c) Combination of H1 and H2 antagonists (d) None of the above
Last Answer : Ans: C
Description : The symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cell (e) Decreased prostaglandin production
Description : In patients of bronchial asthma inhaled corticosteroids achieve the following except (a) Reduce the need for bronchodilator medication (b) Control an attack of refractory asthma (c) Reduce bronchial hyperreactivity (d) Reverse diminished responsiveness to sympathomimetic bronchodilators
Last Answer : Ans: B
Description : The most consistent, pronounced and sustained relief of symptoms in chronic bronchial asthma is afforded by (a) ß2 sympathomimetics (b) Anticholinergics (c) Sodium cromoglycate (d) Corticosteroids
Last Answer : Ans: D
Description : In a patient of bronchial asthma, inhaled salbutamol produces the following effect(s). (a) Inhibits antigen-antibody reaction in the lungs (b) Causes bronchodilatation (c) Reduces bronchial hyperreactivity (d) Both (b) and (c)
Description : The Symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cells (e) Decreased prostaglandin production
Description : Select the H1 antihistaminic which is used topically in the nose for allergic rhinitis (a) Deep intra-abdominal operation (b) Trachial intubation (c) Tetanus (d) Diagonosis of myasthenia gravis
Description : The following class(es) of drugs are clinically beneficial in bronchial asthma: A. Histamine H1 receptor antagonists B. Platelet activating factor (PAF) antagonists C. Leukotriene ( cys LT1) receptor antagonists D. All of the above
Last Answer : C. Leukotriene ( cys LT1) receptor antagonists
Description : Antitussives act by (a) Liquifying bronchial secretions (b) Raising the threshold of cough centre (c) Reducing cough inducing impulses from the lungs (d) Both (b) and (c)
Description : Bromhexine acts by (a) Inhibiting cough center (b) Irritating gastric mucosa and reflexly increasing bronchial secretion (c) Depolymerizing mucopolysaccharides present (d) Desensitizing stretch receptors in the lungs
Description : Smooth muscle relaxation is due to stimulation of which type of histamine receptors (a) H1 (b) H2 (c) H3 (d) All of the above
Description : The most important receptor involved in cytotoxic drug induced vomiting is (a) Histamine H1 receptor (b) Serotonin 5-HT3 receptor (c) Dopamine D2 receptor (d) Opioid µ receptor
Description : The capacity of an antihistaminic to produce sedation depends on the following except (a) Relative affinity for central versus peripheral H1 receptors (b) Ability to penetrate blood-brain barrier (c) Individual susceptibility (d) Ratio of H1 : H2 blockade produced by the drug
Description : Which of the following is a selective H1 receptor agoinist ? (a) 4-methyl histamine (b) Impromidine (c) 2-Thiazolyl ethylamine (d) Mepyramine
Description : The following allergic drug reaction is caused by circulating antibodies: A. Serum sickness B. Anaphylactic shock C. Systemic lupus erythematosus D. Angioedema
Last Answer : A. Serum sickness
Description : The National Institutes of Health (NIH) guidelines for the treatment of asthma recommended institution of routine inhaled corticosteroids when patients are classified as having greater than or equal to which ... (a) Mild intermittent (b) Mild persistent (c) Moderate persistent (d) Severe persistent
Description : Benefit afforded by certain H1 antihistaminics in the following condition is not based on antagonism of histamine: A. Dermographism B. Insect bite C. Common cold D. Seasonal hay fever
Last Answer : C. Common cold
Description : Acute exacerbations of asthma can be triggered by all of the following except (a) Bacterial or viral pneumonia (b) Hypersensitivity reaction to penicillin (c) Discontinuation of asthma medication (d) Hot, dry weather (e) Stressful emotional events
Description : Relative to fexofenadine, diphenhydramine is more likely to (a) Be used for treatment of asthma (b) Be used for treatment of gastroesophageal reflux disease (c) Cause cardiac arrhythmias in ... ) Have efficacy in the prevention of motion sickness (e) Increase the serum concentration of warfarin
Description : A drug useful in the treatment of asthma but lacking bronchodilator action, is (a) Cromolyn (b) Ephedrine (c) Isoproterenol (d) Metaproterenol (e) Metoprolol
Description : Which of the following is a very longacting ß2 – selective agonist that is used for asthma prophylaxis? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Salmeterol
Last Answer : Ans: E
Description : Acute exacerbations of asthma can be triggered by all of the following except (a) Bacterial of viral pneumonia (b) Hypertsensitivity reaction to penicillin (c) Discontinuation of asthma medication (d) Hot, dry weather (e) Stressful emotional events
Description : Which of the following is a direct bronchodilator that is most often used in asthma by the oral route? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Description : Which xanthine derivative has no function in asthma ? (a) Theophylline (b) Pentoxyphyllin (c) Enprofylin (d) None of the above
Description : All the following are employed in inhalation therapy of asthma except (a) Beclomethasone (b) Budesonide (c) Dexamethasone (d) Triamcinolone
Description : In an asthma patient treated with systemic corticosteroids, bronchodilator drugs (a) Are not needed (b) Are contraindicated (c) May be used on ‘as and when required’ basis (d) Are ineffective
Description : Budesonide is a (a) Nonsteroidal anti-inflammatory drug (b) High ceiling diuretic (c) Inhaled corticosteroid for asthma (d) Contraceptive
Description : A 10 year old child suffers from exercise induced asthma: Which is the most suitable first line drug for regular prophylactic therapy ? (a) Oral salbutamol (b) Oral theophylline (c) Inhaled sodium cromoglycate (d) Inhaled beclomethasone dipropionate
Description : Which of the following tests is used at home to assess therapy and determine if a patient with asthma should seek emergency care? (a) Forced expiratory volume in one second (FEV1) (b) Forced vital capacity ... ) Total lung capacity (TLC) (d) Peak expiratory flow rate (PEFR) (e) Residual volume (RV)
Description : The primary goals of asthma therapy include all of the following except (a) maintain normal activity levels (b) maintain control of symptoms (c) avoid adverse effects of asthma medications (d) prevent acute exacerbations and chronic symptoms (e) prevent destruction of lung tissue
Description : In the emergency department, the preferred first-line therapy for asthma exacerbation is (a) Theophylline (b) A ß-agonist (c) A corticosteroid (d) Cromolyn sodium (e) An antihistamine
Description : Isoxuprine is used to treat (a) Asthma (b) Severe hypotension (c) Nasal congestion (d) Premature labor (e) Hypertension
Description : Which of the following may precipitate an asthma attack? (a) Respiratory acidosis (b) Viran and bacterial infections (c) Respiratory alkalosis (d) Cranberry jiuce (e) Chocolate or Coca Cola
Description : A drug administered by inhalation of powder as a prophylactic for asthma is (a) Ephedrine (b) Disodium cromolyn (c) Isoproterenol (d) Ocytriphylline (e) Epinephrine
Description : Which of the following agents and dosage regimens is the best choice of treatment for an asthma patient with rheumatoid arthritis who is considered sensitive to aspirin (experiences bronchospasm with use)? ... once a week (d) Azathioprine, 75 mg daily (e) Cyclophosphamide, 100 mg daily
Description : In the emergency department, the preferred first-line therapy for asthma exacerbation is (a) Theophyline (b) A ß-agonist (c) A corticosteroid (d) Cromolyn sodium (e) An antihistamine
Description : If therapy with multiple drugs causes induction of drug metabolism in your asthma patient, it will (a) Result in increased smooth endoplasmic reticulum (b) Result in increased rough endoplasmic reticulum ... soluble cytoplasmic fraction (d) Require 3-4 months to reach completion (e) Be irreversible
Description : Which of the following terms best describes the antagonism of leukotriene's bronchoconstrictor effect (mediated at leukotriene receptors) by terbutaline (acting a adrenoceptors) in a patient with ... ) Partial agonist (c) Physiologic antagonist (d) Chemical antagonist (e) Noncompetitive antagonist
Description : The nurse anticipates that the immunosuppressed patient is at greatest risk for which type of shock? a) Septic Septic shock is associated with immunosuppression, extremes of age, ... disease of the heart. d) Anaphylactic Anaphylactic shock is associated with hypersensitivity reactions.
Last Answer : a) Septic Septic shock is associated with immunosuppression, extremes of age, malnourishment, chronic illness, and invasive procedures.
Description : Sodium cromoglycate has a role in the treatment of the following conditions except: A. Chronic bronchial asthma B. Chronic urticaria C. Chronic allergic rhinitis D. Chronic allergic conjunctivitis
Last Answer : B. Chronic urticaria
Description : The conventional H1 antihistaminics possess the following additional properties except: A. Local anaesthetic B. Vasopressor C. Antiarrhythmic D. Catecholamine potentiating
Last Answer : B. Vasopressor
Description : Fall in blood pressure caused by larger doses of histamine is blocked by: A. H1 antihistaminics alone B. H2 antagonists alone C. Combination of H1 and H2 antagonists D. None of the above
Last Answer : C. Combination of H1 and H2 antagonists
Description : The second generation H1 antihistaminics have the following advantages except: A. Lack of anticholinergic side effects B. Lack of alcohol potentiating potential C. Recipient can drive motor vehicles D. Good antipruritic action
Last Answer : D. Good antipruritic action
Description : Which of the following is the only life saving measure in case of anaphylactic shock: A. Intravenous hydrocortisone hemisuccinate B. Intravenous chlorpheniramine maleate C. Intramuscular adrenaline hydrochloride D. Intravenous glucose-saline
Last Answer : C. Intramuscular adrenaline hydrochloride