Description : Hyoscine differs from atropine in that it: A. Exerts depressant effects on the CNS at relatively low doses B. Exerts more potent effects on the heart than on the eye C. Is longer acting D. Has weaker antimotion sickness activity
Last Answer : A. Exerts depressant effects on the CNS at relatively low doses
Description : The quarternary analogues of belladonna alkaloids are preferred over the natural alkaloids for antisecretory/ antispasmodic indications because: A. They have additional nicotinic receptor blocking activity B. They are ... of CNS and ocular effects D. Dose to dose they are more potent than atropine
Last Answer : C. They are devoid of CNS and ocular effects
Description : The most effective antimotion sickness drug suitable for short brisk journies is: A. Promethazine theoclate B. Cinnarizine C. Prochlorperazine D. Hyoscine
Last Answer : D. Hyoscine
Description : Ranitidine differs from cimetidine in the following respect: A. It is less potent B. It is shorter acting C. It does not have antiandrogenic action D. It produces more CNS side effect
Last Answer : C. It does not have antiandrogenic action
Description : Glycopyrrolate is the preferred antimuscannic drug for use before and during surgery because (a) It is potent and fast acting (b) It has no central action (c) It has antisecretory and vagolytic actions (d) All of the above
Last Answer : Ans: D
Description : Pyridostigmine differs from neostigmine in that (a) More potent orally (b) Longer acting (c) Less muscarinic side effects (d) All of the above
Last Answer : Ans: B
Description : Pyridostigmine differs from neostigmine in that: A. It is more potent orally B. It is longer acting C. It produces less muscarinic side effects D. It does not have any direct action on NM receptors
Last Answer : B. It is longer acting
Description : A patient has been taking digoxin for several years for chronic heart failure is about to receive atropine for another condition. A common effect of digoxin (at therapeutic blood levels) that can ... Increased atrial contractility (c) Increased PR interval on the ECG (d) Headaches (e) Tachycardia
Last Answer : Ans: C
Description : Low doses of adrenaline dilate the following vascular bed (a) Cutaneous (b) Mucosal (c) Renal (d) Skeletal muscle
Description : Dexamethasone differs from prednisolone in that it is: A. Longer acting B. More potent C. More selective D. All of the above
Last Answer : D. All of the above
Description : The ‘amine’ ergot alkaloid differs from ‘amino acid’ ergot alkaloid in that it has: A. High oral bioavailability B. Better CNS penetrability C. Weaker oxytocic action D. Strong anti-5-HT action
Last Answer : A. High oral bioavailability
Description : Atropine is contraindicated in (a) Cyclic AMP (b) Inositol trisphosphate (c) Diacyl glycerols (d) G protein
Description : The most suitable mydratic for a patient of corneal ulcer is (a) Atropine sulfate (b) Homatropine (c) Cyclopentolate (d) Tropicamide
Last Answer : Ans: A
Description : Which of the following mydriatics has the fastest and briefest action ? (a) Atropine (b) Homatropine (c) Tropicamide (d) Cyclopentolate
Description : Atropine does not exert relaxant/ antispasmodic effect on the following muscle (a) Intestinal (b) Ureteric (c) Bronchial (d) Layngeal
Description : A 70-year-old man has severe urinary hesitancy associated with benign prostatic hyperplasia. He has tried alpha blockers with little relief. His physician recommends a drug that blocks 5a - reductase in ... prescription for (a) Atropine (b) Clonidine (c) Hydralazine (d) Neostigmine (e) Propranolol
Description : Which one of the following can be blocked by atropine? (a) Decreased blood pressure caused by hexamethonium (b) Increased blood pressure caused by nicotine (c) Increased skeleton muscle ... by neostigmine (d) Tachycardia caused by exercise (e) Tachycardia caused by infusion of acetylcholine
Last Answer : Ans: E
Description : Atropine overdose may cause which one of the following (a) Gastrointestinal smooth muscle crampine (b) Increased cardiac rate (c) Increased gastric secretion (d) Pupillary constriction (e) Urinary frequency
Description : The following is not a feature of second generation antihistaminics: A. Nonimpairment of psychomotor performance B. High antimotion sickness activity C. Absence of anticholinergic/anti5 -HTa ctions D. Additional mechanisms of antiallergic action
Last Answer : B. High antimotion sickness activity
Description : A drug that is useful in glaucoma and high-altitude sickness is (a) Acetazolamide (b) Amiloride (c) Demeclocycline (d) Desmopressin (e) Ethacrynic acid
Description : Accepted therapeutic indications for the use of antimuscarinic drugs include all of the following except (a) Hypertension (b) Motion sickness (c) Parkinson’s disease (d) Postoperative bladder spasm (e) Traveler’s diarrhea
Description : Select the correct statement about flumazenil: A. It is a CNS stimulant used as an antidote for benzodiazepine poisoning B. It is a CNS depressant but blocks the action of diazepam C. It has ... of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines
Last Answer : D. It has no CNS effect of its own but blocks the depressant effect of diazepam as well as stimulant effect of beta carbolines
Description : Dobutamine differs from dopamine in that (a) It does not activate peripheral dopaminergic receptors (b) It does not activate adrenergic ß receptors (c) It causes pronounced tachycardia (d) It has good blood-brain barrier penetrability
Description : Drugs that block the a receptor on effector cells at adrenergic nerve endings (a) Antagonize the effects of isoproterenol on the heart rate (b) Antagonize some of the effects of epinephrine on ... the effects of epinephrine on adenylyl cyclase (d) Cause mydriasis (e) Decreases blood glucose levels
Description : In a patient given a cardiac glycoside, important effects of the drug on the heart include which of the following? (a) Decreased atrioventricular conduction velocity (b) Decreased ejection time (c) Increased ectopic automaticity (d) Increased ectopic automaticity (e) All of the above
Description : Nitroglycerin, either directly or through reflexes, results in which one of the following effects (a) Decreased heart rate (b) Decreased venous capacitance (c) Increased afterload (d) Increased cardiac force (e) Increased diastolic intramyocardial fiber tension
Description : Desmopressin is preferred over arginine vasopressin in the treatment of diabetes insipidus for the following reasons except: A. It is a more potent antidiuretic B. It is a selective vasopressin V1 receptor agonist C. It has little vasoconstrictor activity D. It is longer acting
Last Answer : B. It is a selective vasopressin V1 receptor agonist
Description : Out of two anticholinesterases, drug X' is a tertiary amine while drug Y' is a quarternary ammonium compound. Then: A. Drug X' is likely to be more potent than Y' B. Drug X' will be more ... a miotic C. Drug Y' will be completely metabolized in the body D. Drug Y' will produce CNS effects
Last Answer : B. Drug ‘X’ will be more suitable to be used as a miotic
Description : The progestin used in combined oral contraceptive pill is a 19-nortestosterone derivative because: A. They have potent antiovulatory action of their own B. They do not produce any metabolic effects C. They produce fewer side effects D. They are longer acting
Last Answer : A. They have potent antiovulatory action of their own
Description : Choose the correct statement about codeine: A. It has a lower oral: parenteral activity ratio than morphine B. It is devoid of abuse liability C. It is a weaker analgesic than morphine D. It is a more potent antitussive than morphine
Last Answer : C. It is a weaker analgesic than morphine
Description : A 7-years-old boy has a significant bedwetting problem. A long-acting indirect sympathomimetic agent sometimes used by the oral route for this and other indications is (a) Dobutamine (b) Ephedrine (c) Epinephrine (d) Isoproterenol (e) Phenylephrine
Description : A direct-acting cholinomimetic that is lipid-soluble and often used in the treatment of glaucoma is (a) Acetylcholine (b) Bethanechol (c) Physostigmine (d) Pilocarpine (e) Neostigmine
Description : Betaxolol differs from timolol in that it: A. Is a β1 selective blocker B. Is more efficacious in glaucoma C. Produces less ocular side effects D. Is longer acting
Last Answer : A. Is a β1 selective blocker
Description : The mydriatic incapable of producing cycloplegia sufficient for refraction testing in children is: A. Atropine B. Hyoscine C. Homatropine D. Cyclopentolate
Last Answer : C. Homatropine
Description : In case of hill journey, antimotion sickness drugs are best administered at: A. Twelve hours before commencing journey B. One hour before commencing journey C. Immediately after commencing journey D. At the first feeling of motion sickness
Last Answer : B. One hour before commencing journey
Description : 'Diffusion hypoxia’ is likely to occur only after use of nitrous oxide because it: A. Is a respiratory depressant B. Has low blood solubility and is used in high concentration C. Is a very potent anaesthetic D. Interferes with diffusion of oxygen into the tissues
Last Answer : B. Has low blood solubility and is used in high concentration
Description : Enalapril differs from captopril in the following features except: A. It is dose to dose more potent B. Its oral absorption is not affected by food in stomach C. It acts more rapidly D. It has longer duration of action
Last Answer : D. Lisinopri
Description : riiodothyronine differs from thyroxine in that: A. It is more avidly bound to plasma proteins B. It has a shorter plasma half life C. It is less potent D. It has a longer latency of action
Last Answer : B. It has a shorter plasma half life
Description : 17.2 Triiodothyronine differs from thyroxine in that: A. It is more avidly bound to plasma proteins B. It has a shorter plasma half life C. It is less potent D. It has a longer latency of action (
Description : The ß-adrenergic blocker which possesses both ß1 selectivity as well as intrinsic sympathomimetic activity is (a) Alprenolol (b) Atenolol (c) Acebutolol (d) Metoprolol
Description : a2–adrenergic receptors are associated with following except (a) Increase in phospholipase C activity (b) Increase in potassium channel conductance (c) Decrease in calcium channel conductance (d) Increase in adenylyl cyclase activity
Description : Which of the following is not a CNS depressant but increases the tendency to fall asleep at night: A. Pyridoxine B. Diphenhydramine C. Melatonin D. Ethanol
Last Answer : C. Melatonin
Description : Ephedrine is similar to adrenaline in the following feature (a) Potency (b) Inability to penetrate blood-brain barrier (c) Duration of action (d) Producing both a and ß adrenergic effects
Description : Recognized adverse effects of quinidine include which one of the following? (a) Cinchonism (b) Constipation (c) Lupus erythematosus (d) Increase in digoxin clearance (e) Precipitation of hyperthyroidism