Among the following, the most sensitive indicator of glomerular function is (A) Serum urea (B) Serum creatinine (C) Urea clearance (D) Creatinine clearance

Among the following, the most sensitive indicator of glomerular function is (A) Serum urea (B) Serum creatinine (C) Urea clearance (D) Creatinine clearance
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Among the following, a test of Glomerular function is (A) Urea clearance (B) PSP excretion test (C) PAH clearance (D) Hippuric acid excretion test

Description : Among the following, a test of Glomerular function is (A) Urea clearance (B) PSP excretion test (C) PAH clearance (D) Hippuric acid excretion test

Last Answer : Answer : D

Creatinine EDTA clearance is a test to measure (A) Renal plasma flow (B) Filtration fraction (C) Glomerular filtration rate (D) Tubular function

Description : Creatinine EDTA clearance is a test to measure (A) Renal plasma flow (B) Filtration fraction (C) Glomerular filtration rate (D) Tubular function

Last Answer : Answer : C

Glomerular filtration rate can be measured by (A) Endogenous creatinine clearance (B) Para-aminohippurate test (C) Addis test (D) Mosenthal test

Description : Glomerular filtration rate can be measured by (A) Endogenous creatinine clearance (B) Para-aminohippurate test (C) Addis test (D) Mosenthal test

Last Answer : Answer : A

A simple way to assess tubular function is to withhold food and water for 12 hours and, then, measure (A) Serum urea (B) Serum creatinine (C) Urine output in one hour (D) Specific gravity of urine

Description : A simple way to assess tubular function is to withhold food and water for 12 hours and, then, measure (A) Serum urea (B) Serum creatinine (C) Urine output in one hour (D) Specific gravity of urine

Last Answer : Answer : D

A 15-year-old girl was seen by her family physician because of increasing lethargy. She had a recent history of the "flu". Biochemistry tests show that she has renal impairement. serum sodium 140 mmol/L (137 - 144) serum potassium 4.2 mmol/L (3.5 - 4.9) serum urea 28 mol/L (2.5 - 7.5) serum creatinine 280 µmol/L (60 - 110) Her condition does not improve after several weeks on corticosteroid therapy, so a renal biopsy is performed. The biopsy demonstrates the presence of segmental sclerosis of 3 of 10 glomeruli identified in the biopsy specimen. Immunofluorescence studies and electron microscopy do not reveal evidence for immune deposits. What is the most appropriate advice to give regarding her condition? 1) She has an underlying malignancy 2) She may require a renal transplant in 10 years

Description : A 15-year-old girl was seen by her family physician because of increasing lethargy. She had a recent history of the "flu". Biochemistry tests show that she has renal impairement. ... will likely develop a restrictive lung disease 5) She will probably improve with additional corticosteroid therapy

Last Answer : Answers-2 The findings point to focal segmental glomerulosclerosis (FSGS), which leads to chronic renal failure in half of cases. The lack of resolution with corticosteroid therapy and the progression to chronic renal failure is what sets FSGS apart from minimal change disease.

Urea clearance test is used to determine the (A) Glomerular filtration rate (B) Renal plasma flow (C) Ability of kidney to concentrate the urine (D) Measurement of tubular mass

Description : Urea clearance test is used to determine the (A) Glomerular filtration rate (B) Renal plasma flow (C) Ability of kidney to concentrate the urine (D) Measurement of tubular mass

Last Answer : Answer : A

Among the following, a test of tubular function is (A) Creatinine clearance (B) Inulin clearance (C) PAH clearance (D) PSP excretion test

Description : Among the following, a test of tubular function is (A) Creatinine clearance (B) Inulin clearance (C) PAH clearance (D) PSP excretion test

Last Answer : Answer : D

Rank the following laboratory tests and procedures in terms of their relative value to a 65-year-old woman who is to undergo elective resection of a sigmoid cancer. A. Carcinoembryonic antigen (CEA). B. Blood urea nitrogen (BUN). C. Electrocardiogram (ECG). D. Hemoglobin concentration (Hgb). E. Serum creatinine (Cr). F. Arterial blood oxygen tension (PaO 2) on room air. G. Serum sodium concentration (Na+).

Description : Rank the following laboratory tests and procedures in terms of their relative value to a 65-year-old woman who is to undergo elective resection of a sigmoid cancer. A. Carcinoembryonic antigen (CEA). B. ... Arterial blood oxygen tension (PaO 2) on room air. G. Serum sodium concentration (Na+).

Last Answer : Answer: CDFEBAG DISCUSSION: The most important test by far is the electrocardiogram, with its capacity to indicate signs of occult heart disease. The second most important evaluation is the hemoglobin ... for resection of the colon is always normal and would be of least value among these tests

The following findings are normal in pregnancy: a. elevated erythrocyte sedimentation rate (ESR) b. raised serum urea c. raised serum creatinine d. elevated white blood cell count

Description : The following findings are normal in pregnancy: a. elevated erythrocyte sedimentation rate (ESR) b. raised serum urea c. raised serum creatinine d. elevated white blood cell count

Last Answer : elevated white blood cell count

The normal values for creatinine clearance varies from (A) 20–40 ml/min (B) 40–60 ml/min (C) 70–85 ml/min (D) 95–105 ml/min

Description : The normal values for creatinine clearance varies from (A) 20–40 ml/min (B) 40–60 ml/min (C) 70–85 ml/min (D) 95–105 ml/min

Last Answer : Answer : D

Creatinine clearance is deceased in (A) Acute tubular necrosis (B) Acute glomerulonephritis (C) Hypertension (D) Myopathies

Description : Creatinine clearance is deceased in (A) Acute tubular necrosis (B) Acute glomerulonephritis (C) Hypertension (D) Myopathies

Last Answer : Answer : D

Average creatinine clearance in an adult man is about (A) 54 ml/min (B) 75 ml/min (C) 110 ml/min (D) 130 ml/min

Description : Average creatinine clearance in an adult man is about (A) 54 ml/min (B) 75 ml/min (C) 110 ml/min (D) 130 ml/min

Last Answer : Answer : C

Para-amino hippurate excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal plasma flow

Description : Para-amino hippurate excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal plasma flow

Last Answer : Answer : D

Phenolsulphonephthalein excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal blood low

Description : Phenolsulphonephthalein excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal blood low

Last Answer : Answer : D

Normal range of serum creatinine is (A) 0.6–1.5 mg/dl (B) 9–11 mg/dl (C) 20–45 mg/dl (D) 60–100 mg/dl

Description : Normal range of serum creatinine is (A) 0.6–1.5 mg/dl (B) 9–11 mg/dl (C) 20–45 mg/dl (D) 60–100 mg/dl

Last Answer : Answer : A

Organic compound of small molecular size is (A) Urea (B) Uric acid (C) Creatinine (D) Phosphates

Description : Organic compound of small molecular size is (A) Urea (B) Uric acid (C) Creatinine (D) Phosphates

Last Answer : Answer : A

When NH3 is perfused through a dog’s liver ______ is formed, while ______ is formed in the birds liver. (A) Urea, Uric acid (B) Urea, allantoin (C) Uric acid, creatinine (D) Uric acid, Urea

Description : When NH3 is perfused through a dog’s liver ______ is formed, while ______ is formed in the birds liver. (A) Urea, Uric acid (B) Urea, allantoin (C) Uric acid, creatinine (D) Uric acid, Urea

Last Answer : Answer : A

Gout is characterized by increased plasma levels of (A) Urea (B) Uric acid (C) Creatine (D) Creatinine

Description : Gout is characterized by increased plasma levels of (A) Urea (B) Uric acid (C) Creatine (D) Creatinine

Last Answer : Answer : B

Mechanism by which NH3 is removed from the kidneys is (A) Urea formation (B) Uric acid formation (C) Creatinine formation (D) None of these

Description : Mechanism by which NH3 is removed from the kidneys is (A) Urea formation (B) Uric acid formation (C) Creatinine formation (D) None of these

Last Answer : Answer : D

NH3 is removed from brain mainly by (A) Creatinine formation (B) Uric acid production (C) Urea formation (D) Glutamine formation

Description : NH3 is removed from brain mainly by (A) Creatinine formation (B) Uric acid production (C) Urea formation (D) Glutamine formation

Last Answer : Answer : D

In humans, NH3 is detoxified in liver as (A) Creatinine (B) Uric acid (C) Urea (D) Uronic acid

Description : In humans, NH3 is detoxified in liver as (A) Creatinine (B) Uric acid (C) Urea (D) Uronic acid

Last Answer : Answer : C

NH3 is detoxified in brain chiefly as (A) Urea (B) Uric acid (C) Creatinine (D) Glutamine

Description : NH3 is detoxified in brain chiefly as (A) Urea (B) Uric acid (C) Creatinine (D) Glutamine

Last Answer : Answer : D

Non-protein nitrogenous substances in blood include all of the following except (A) Urea (B) Uric acid (C) Creatinine (D) Inositol

Description : Non-protein nitrogenous substances in blood include all of the following except (A) Urea (B) Uric acid (C) Creatinine (D) Inositol

Last Answer : Answer : C

Which of the following statement(s) concerning laboratory studies used in monitoring a patient with intravenous heparinization is/are correct? a. The platelet count should be followed because of the risk of heparin-associated thrombocytopenia b. The prothrombin time should be observed if prolonged treatment is necessary c. The activated partial thromboplastin time (aPTT) should be maintained at approximately 1.5 times normal d. The serum creatinine should be measured daily to allow adjustments in dose based on renal function

Description : Which of the following statement(s) concerning laboratory studies used in monitoring a patient with intravenous heparinization is/are correct? a. The platelet count should be followed because of the ... serum creatinine should be measured daily to allow adjustments in dose based on renal function

Last Answer : Answer: a, c In monitoring the effect of heparin, an activated partial thromboplastin time (aPTT) of 1.5 control or a thrombin clotting time (TCT) of 2 times control reflects adequate ... system. Therefore the dose of heparin need not be adjusted in cases of liver or renal dysfunction

Inulin clearance is a measure of (A) Glomerular filtration rate (B) Tubular secretion flow (C) Tubular reabsorption rate (D) Renal plasma flow

Description : Inulin clearance is a measure of (A) Glomerular filtration rate (B) Tubular secretion flow (C) Tubular reabsorption rate (D) Renal plasma flow

Last Answer : Answer : B

Measurement of insulin clearance test is a measure of (A) Glomerular filtration rate (B) Filtration factor (C) Renal plasma flow (D) Tubular secretory mass

Description : Measurement of insulin clearance test is a measure of (A) Glomerular filtration rate (B) Filtration factor (C) Renal plasma flow (D) Tubular secretory mass

Last Answer : Answer : A

Creatinine clearance?

Description : Creatinine clearance?

Last Answer : DefinitionThe creatinine clearance test compares the level of creatinine in urine with the creatinine level in the blood. (Creatinine is a breakdown product of creatine, which is an important part of muscle. ... urine and blood samples, and looks at how much urine you collected in 24 hours.The clear

60-year-old patient with creatinine clearance 50 ml/min has to be treated with gentamicin. His daily dose of gentamicin should be reduced to the following percentage of the usual adult dose: A. 70% B. 50% C. 40% D. 30%

Description : 60-year-old patient with creatinine clearance 50 ml/min has to be treated with gentamicin. His daily dose of gentamicin should be reduced to the following percentage of the usual adult dose: A. 70% B. 50% C. 40% D. 30%

Last Answer : B. 50%

A 60-year-old patient with creatinine clearance 50 ml/min has to be treated with gentamicin. His daily dose of gentamicin should be reduced to the following percentage of the usual adult dose: A. 70% B. 50% C. 40% D. 30%

Description : A 60-year-old patient with creatinine clearance 50 ml/min has to be treated with gentamicin. His daily dose of gentamicin should be reduced to the following percentage of the usual adult dose: A. 70% B. 50% C. 40% D. 30%

Last Answer : B. 50%

In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil

Description : In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil

Last Answer : B. Digoxin

In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil

Description : In patients with renal insufficiency the clearance of the following drug is reduced parallel to the reduction in creatinine clearance: A. Propranolol B. Digoxin C. Lignocaine D. Verapamil

Last Answer : B. Digoxin

A 75-year-old man had been receiving gentamicin (an aminoglycoside antibiotic) to treat an urinary tract infection. After three months of therapy patient's serum creatinine levels were 10 mg/dL ( normal 0.5-1.2) and serum gentamicin concentrations obtained just before the last dose were 9 mg/dL (normal < 2). Which of the following is the most likely adverse drug reaction the patient was suffering from? a) Type II allergic reaction b)Type III allergic reaction c) Pseudo allergic reaction d) Overdose toxicity

Description : A 75-year-old man had been receiving gentamicin (an aminoglycoside antibiotic) to treat an urinary tract infection. After three months of therapy patient's serum creatinine levels were 10 mg/ ... Type II allergic reaction b)Type III allergic reaction c) Pseudo allergic reaction d) Overdose toxicity

Last Answer : d) Overdose toxicity 

In early stages of myocardial ischemia the most sensitive indicator is the measurement of the activity of (A) CPK (B) SGPT (C) SGOT (D) LDH

Description : In early stages of myocardial ischemia the most sensitive indicator is the measurement of the activity of (A) CPK (B) SGPT (C) SGOT (D) LDH

Last Answer : Answer : A

Essential amino acids have been advocated as standard therapy for renal failure. Which of the following statements are true? A. Increased survival from acute renal failure has been reported with both essential and nonessential amino acid therapy of patients in renal failure. B. Essential amino acids retard the rise of blood urea nitrogen (BUN) secondary to decreased urea appearance. C. Essential amino acids and hypertonic dextrose are a convenient form of therapy for hyperkalemia. D. Essential amino acids decrease BUN and creatinine to the same degree as solutions containing excessive nonessential amino acids.

Description : Essential amino acids have been advocated as standard therapy for renal failure. Which of the following statements are true? A. Increased survival from acute renal failure has been reported ... BUN and creatinine to the same degree as solutions containing excessive nonessential amino acids.

Last Answer : Answer: BC DISCUSSION: Essential amino acids and hypertonic dextrose, as opposed to hypertonic dextrose alone, was reported by Abel and co-workers to be associated with a decreased mortality rate ... renal failure have not been carried out in sufficient numbers to yield answers to this question

The abnormal constituent of urine is – (1) urea (2) creatinine (3) albumin (4) sodium

Description : The abnormal constituent of urine is – (1) urea (2) creatinine (3) albumin (4) sodium

Last Answer : (3) albumin Explanation: The tests employed to detect commonly present abnormal constituents are proteins, glucose, ketone bodies, bile pigments, bile salts and blood. The liver synthesizes a type of ... easily get trapped in the kidney's filter and finally they are reabsorbed in the blood stream.

Which one of the following is an abnormal constituent of urine? (1) Creatinine (2) Urea (3) Uric acid (4) Ketone bodies

Description : Which one of the following is an abnormal constituent of urine? (1) Creatinine (2) Urea (3) Uric acid (4) Ketone bodies

Last Answer : (4) Ketone bodies Explanation: Ketone bodies are three watersoluble compounds that are produced as byproducts when fatty acids are broken down for energy in the liver. Two of the three are ... exceeds the rate of utilization, their concentration in blood increases, this is known as ketonemia.

The abnormal constituent of urine is (1) urea (2) creatinine (3) albumin (4) sodium

Description : The abnormal constituent of urine is (1) urea (2) creatinine (3) albumin (4) sodium

Last Answer : albumin

Which one of the following is an abnormal constituent of urine ? (1) Creatinine (2) Urea (3) Uric acid (4)Ketone bodies

Description : Which one of the following is an abnormal constituent of urine ? (1) Creatinine (2) Urea (3) Uric acid (4)Ketone bodies

Last Answer : Ketone bodies

Filtration fraction can be calculated from (A) Standard urea clearance and PSP excretion (B) Maximum urea clearance and PSP excretion (C) Maximum urea clearance and PAH clearance (D) Inulin clearance and PAH clearance

Description : Filtration fraction can be calculated from (A) Standard urea clearance and PSP excretion (B) Maximum urea clearance and PSP excretion (C) Maximum urea clearance and PAH clearance (D) Inulin clearance and PAH clearance

Last Answer : Answer : A

Urea clearance is the (A) Amount of urea excreted per minute (B) Amount of urea present in 100 ml of urine (C) Volume of blood cleared of urea in one minute (D) Amount of urea filtered by glomeruli in one minute

Description : Urea clearance is the (A) Amount of urea excreted per minute (B) Amount of urea present in 100 ml of urine (C) Volume of blood cleared of urea in one minute (D) Amount of urea filtered by glomeruli in one minute

Last Answer : Answer : A

Urea clearance is lowered in (A) Acute nephritis (B) Pneumonia (C) Early stage of nephritic syndrome (D) Benign hypertension

Description : Urea clearance is lowered in (A) Acute nephritis (B) Pneumonia (C) Early stage of nephritic syndrome (D) Benign hypertension

Last Answer : Answer : A

The average normal value for standard urea clearance is (A) 20 ml (B) 30 ml (C) 40 ml (D) 54 ml

Description : The average normal value for standard urea clearance is (A) 20 ml (B) 30 ml (C) 40 ml (D) 54 ml

Last Answer : Answer : D

Average maximum urea clearance is (A) 30 ml (B) 50 ml (C) 75 ml (D) 90 ml

Description : Average maximum urea clearance is (A) 30 ml (B) 50 ml (C) 75 ml (D) 90 ml

Last Answer : Answer : C

The formula to calculate maximum urea clearance is U V× B , where U denotes (A) Concentration of urea in urine in gm/24hr (B) Concentration of urea in urine in mg/100 ml (C) Concentration of urea in blood in mg/100 ml (D) Volume of urine in ml/mt

Description : The formula to calculate maximum urea clearance is U V× B , where U denotes (A) Concentration of urea in urine in gm/24hr (B) Concentration of urea in urine in mg/100 ml (C) Concentration of urea in blood in mg/100 ml (D) Volume of urine in ml/mt

Last Answer : Answer : B

Maximum urea clearance is (A) 54 ml/min (B) 75 ml/min (C) 110 ml/min (D) 130 ml/min

Description : Maximum urea clearance is (A) 54 ml/min (B) 75 ml/min (C) 110 ml/min (D) 130 ml/min

Last Answer : Answer : B

Standard urea clearance is (A) 54 ml/min (B) 75 ml/min (C) 110 ml/min (D) 130 ml/min

Description : Standard urea clearance is (A) 54 ml/min (B) 75 ml/min (C) 110 ml/min (D) 130 ml/min

Last Answer : Answer : A

Measurement of inulin renal clearance is a measure for (A) Effective renal blood flow (B) Renal drug excretion rate (C) Active renal secretion (D) Glomerular filtration rate

Description : Measurement of inulin renal clearance is a measure for (A) Effective renal blood flow (B) Renal drug excretion rate (C) Active renal secretion (D) Glomerular filtration rate

Last Answer : (D) Glomerular filtration rate

If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation

Description : If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation

Last Answer : A. More than the glomerular filtration rate

If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation

Description : If a drug undergoes net tubular secretion, its renal clearance will be: A. More than the glomerular filtration rate B. Equal to the glomerular filtration rate C. Less than the glomerular filtration rate D. Equal to the rate of urine formation

Last Answer : A. More than the glomerular filtration rate